CLUSTAL W(1.81) multiple sequence alignment ENSMUSP00000033263/1-642 ---------------------------------MGIPL-----------------TWMLL ENSRNOP00000021027/1-644 ---------------------------------MGQLLSL---------------TWLLL ENSP00000379442/1-689 MRHIMTRLTLPFWLQDTRHQRQREKFKGPTRLSFGQVLSRPEVAGRAERMGQPSLTWMLM ENSCPOP00000013620/1-593 ------------------------------------------------------------ XP_004855890.1/1-647 ---------------------------------MGRPLSR---------------SWMLV ENSMUSP00000033263/1-642 -VMMVTSWFTLAEASN-STEARRCSECHNNATCTVDGVVTTCSCQTGFTGDGLVCEDMDE ENSRNOP00000021027/1-644 -VMVVTPWFTVAGAND-SPEARRCSECHDNATCVLDGVVTTCSCQAGFTGDGLVCEDIDE ENSP00000379442/1-689 --VVVASWFITTAATD-TSEARWCSECHSNATCTEDEAVTTCTCQEGFTGDGLTCVDLDE ENSCPOP00000013620/1-593 ----------------------RCSDCHSNATCLEDGVITTCTCQDGFSGDGILCTDVDE XP_004855890.1/1-647 AVVVVTSWSLTAAANEPSSEARRCSECHSNATCIEDGVVTTCSCRDGFSGNGLECVDVDE **:**.**** * .:***:*: **:*:*: * *:** ENSMUSP00000033263/1-642 CATPWTHNCS-NSSCVNTPGSFKCSCQDGFRLTPELSCTDVDECSEQGLSNCHALATCVN ENSRNOP00000021027/1-644 CATPWTHNCS-NSICMNTLGSYECSCQDGFRLTPGLGCIDVNECTEQGLSNCHSLATCVN ENSP00000379442/1-689 CAIPGAHNCSANSSCVNTPGSFSCVCPEGFRLSPGLGCTDVDECAEPGLSHCHALATCVN ENSCPOP00000013620/1-593 CAIPGASNCSANSSCVNTLGSYTCACADGFLLRPGLGCIDVDECAEPGLNHCHALATCVN XP_004855890.1/1-647 CATPEAHNCSVGSGCVNTLGSYTCVCPDGFLLTPGLGCTDVDECSEPGLSGCHPLASCVN ** * : *** .* *:** **: * * :** * * *.* **:**:* **. **.**:*** ENSMUSP00000033263/1-642 TEGDYLCVCPEGFTGDGWYCECSPGSCEPGLDCLPQGPDGKLVCQDPCNTYETLTEYWRS ENSRNOP00000021027/1-644 TEGSYSCVCPKGYRGDGWYCECSPGSCEPGLDCLPQGPSGKLVCQDPCNVYETLTEYWRS ENSP00000379442/1-689 VVGSYLCVCPAGYRGDGWHCECSPGSCGPGLDCVPEGD--ALVCADPCQAHRTLDEYWRS ENSCPOP00000013620/1-593 VDGNYSCVCPQGYVGSGLQCECTPGSCGLGLECLPEGQGGALVCVDPCHAYQTLDEYWRS XP_004855890.1/1-647 LDGNYSCVCPEGYAGDGRHCECSPGSCGRGLDCVPAGEHGALVCADPCQAYRTLDQYWRS *.* **** *: *.* ***:**** **:*:* * *** ***:.:.** :**** ENSMUSP00000033263/1-642 TEYGVGYSCDAGLHGWYRFTGQGGVRMAETCVPVLRCNTAAPMWLNGSHPSSSEGIVSRT ENSRNOP00000021027/1-644 TDYGAGYSCDSDMHGWYRFTGQGGVRMAETCVPVLRCNTAAPMWLNGSHPSSREGIVSRT ENSP00000379442/1-689 TEYGEGYACDTDLRGWYRFVGQGGARMAETCVPVLRCNTAAPMWLNGTHPSSDEGIVSRK ENSCPOP00000013620/1-593 AEYGAGFSCDLELRGWYRFVGQSGVRMANTCVPTQRCNTAAPLWLNGTHPSNNEGIVSRK XP_004855890.1/1-647 AEYGAGYSCDSDLRGWYRFVGQGGVRMADTCVPVQRCSTAAPLWLNGTHPSNDEGIVSRT ::** *::** ::*****.**.*.***:****. **.****:****:***. ******. ENSMUSP00000033263/1-642 ACAHWSDQCCRWSTEIQVKACPGGFYIYNLTAPPECNLAYCTDPSSVEGTCEECRVDEDC ENSRNOP00000021027/1-644 ACAHWSDHCCLWSTEIQVKACPGGFYVYNLTEPPECNLAYCTDPSSVEGTCEECGVDEDC ENSP00000379442/1-689 ACAHWSGHCCLWDASVQVKACAGGYYVYNLTAPPECHLAYCTDPSSVEGTCEECSIDEDC ENSCPOP00000013620/1-593 ACAHWSGHCCRWETQVHVKACPGGYYVYNLTAPPECHLAYCTDPTSVEGTCEECSVDEDC XP_004855890.1/1-647 ACAHWSGHCCRWDTRVQLKACAGGYYVYNLTAPPECHLAYCTDPTSVEGTCEECGVDEDC ******.:** *.: :::***.**:*:**** ****:*******:********* :**** ENSMUSP00000033263/1-642 ISDNGRWRCQCKQDSNITDVSQLEYRLECGANDIKMSLRKCQLQSLGFMNVFMYLNDRQC ENSRNOP00000021027/1-644 VSDNGRWRCQCKQDFNITDVSLLEHRLECEANEIKISLSKCQLQSLGFMKVFMYLNDRQC ENSP00000379442/1-689 KSNNGRWHCQCKQDFNITDISLLEHRLECGANDMKVSLGKCQLKSLGFDKVFMYLSDSRC ENSCPOP00000013620/1-593 ISDNGRWHCRCKEDTNVTDVSLLERRLECGVNDMKLSLSKCHLQNLGFKKVFMYLHDSRC XP_004855890.1/1-647 IANNGRWHCQCKQDSNITDVSLLERRLECGASDIKVSLSKCHLKNLGFKKVFMYLRDSRC ::****:*:**:* *:**:* ** **** ..::*:** **:*:.*** :***** * :* ENSMUSP00000033263/1-642 SGFSESDERDWMSIVTPARNGPCGTVLRRNETHATYSNTLYLANAIIIRDIIIRMNFECS ENSRNOP00000021027/1-644 SGFSERGERDWMSIVTPARDGPCGTVLRRNETHATYSNTLYLASEIIIRDINIRINFECS ENSP00000379442/1-689 SGFNDRDNRDWVSVVTPARDGPCGTVLTRNETHATYSNTLYLADEIIIRDLNIKINFACS ENSCPOP00000013620/1-593 SGFMERGERDWMSVVTPARHGPCGTVLTTNETHATYSNTLYLANEIIIRDFNIKFNFECS XP_004855890.1/1-647 FGFMEKGERDWMSVVTPAQDGPCGTVLTRNETHATYSNTLYLANEMIIRDINIKINFECS ** : .:***:*:****:.******* **************. :****: *::** ** ENSMUSP00000033263/1-642 YPLDMKVSLKTSLQPMVSALNISLGGTGKFTVRMALFQSPTYTQPHQGPSVMLSTEAFLY ENSRNOP00000021027/1-644 YPLDMKVSLKTSLQPMVSALNISLGGTGKFTVQMALFQNPTYTQPYQGPSVMLSTEAFLY ENSP00000379442/1-689 YPLDMKVSLKTALQPMVSALNIRVGGTGMFTVRMALFQTPSYTQPYQGSSVTLSTEAFLY ENSCPOP00000013620/1-593 YPLDMKVSLQTSLRPIVSSLNISVGGTGMFTVRMALFQSPAYTQPYQGSSVTLSTEAFLY XP_004855890.1/1-647 YPLDMKVSLKTSLQPVVSSLNISVGGTGLFTVRMALFQSPAYTQPYQGPSVTLSTEAFLY *********:*:*:*:**:*** :**** ***:*****.*:****:**.** ******** ENSMUSP00000033263/1-642 VGTMLDGGDLSRFVLLMTNCYATPSSNSTDPVKYFIIQDSCPRTEDTTIQVTENGESSQA ENSRNOP00000021027/1-644 VGTMLDGGDLSRFVLLMTNCYATPSSNSTDPVKYFIIQDRCPHTEDTTIQVTENGESSQA ENSP00000379442/1-689 VGTMLDGGDLSRFALLMTNCYATPSSNATDPLKYFIIQDRCPHTRDSTIQVVENGESSQG ENSCPOP00000013620/1-593 VGTMLDGGDLSRFVLLMTNCYATPSSNASDPMKYFIIQDRCPRSSDSTIQVMENGESTVG XP_004855890.1/1-647 VGTMLDGGDLSRFALLMTNCYATPSGNATDPTKYFIIQDRCPSTSDSTIQVVENGESPQG *************.***********.*::** ******* ** : *:**** *****. . ENSMUSP00000033263/1-642 RFSVQMFRFAGNYDLVYLHCEVYLCDSTSEQCKPTCSGTRFRSGNFIDQTRVLNLGPITR ENSRNOP00000021027/1-644 RFSIQMFRFAGNSDLVYLHCEVYLCDTMSEQCKPTCSGTRYRSGNFIDQTRVLNLGPITR ENSP00000379442/1-689 RFSVQMFRFAGNYDLVYLHCEVYLCDTMNEKCKPTCSGTRFRSGSVIDQSRVLNLGPITR ENSCPOP00000013620/1-593 RFSVQMFRFAGNYDLVYLHCEVYLCDRVNENCKPTCSGTRVRSGGSIDQSRVLNLGPITR XP_004855890.1/1-647 RFSVQMFRFTGNYDLVYLHCEVYLCDLVNEKCKPSCTGARLRSGGFIDQSRVLNLGPITR ***:*****:** ************* .*:***:*:*:* ***. ***:********** ENSMUSP00000033263/1-642 QGVQASVSKAASSNLRLLSIWLLLFPSATLIFMVQ ENSRNOP00000021027/1-644 QGVQASVSKAASSNLGFLSIWLLLFLSATLTLMVH ENSP00000379442/1-689 KGVQATVSRAFSS-LGLLKVWLPLLLSATLTLTFQ ENSCPOP00000013620/1-593 EGVQAAVSKATSSSL-------------------- XP_004855890.1/1-647 RGVQATVSRAASSSLGLLKIWLPVLLSVTLTVTFQ .****:**:* ** *