CLUSTAL W(1.81) multiple sequence alignment ENSP00000263650/1-879 ------------------------MKEEAFLRRRFSLCPPSSTPQKVDPRKLTRNLLLSG ENSMUSP00000020411/1-898 MALSILSEQFCIRRPRQKPPSTHTMKEEAFLRRRFSLCPPASTPQKTDPRKVPRNLLLGC ENSRNOP00000028119/1-898 MALSILSEQFCIRRPRQKPPSTHTMKEEAFLRRRFSLCPPASTPQKTDPRKLPRNLLLGC ENSCPOP00000013549/1-880 ------------------------MKEEVFLRRRFSLCPPTSTPQKTDPRKLTRHLLLGC XP_004852188.1/1-883 ------------------------MKEEVFLRRRFSLCPPASTPQKTDPRKLTRHLLLGC ****.***********:*****.****:.*:***. ENSP00000263650/1-879 DNELYPLSPGKDMEPNGPSLPRDEGPPTPSSATKVPPAEYRLCNGSDKECVSPTARVTKK ENSMUSP00000020411/1-898 ENELGPITPGRDMESNGPSQPRDEEPQTPGSATKVPLAEYRLCNGSDKECTSPTTRVSKK ENSRNOP00000028119/1-898 ENELGPITPGRDMESNGPSQPRDEEPLTPGSATKVPLAEYRLCNGSDKECTSPTTRVSKK ENSCPOP00000013549/1-880 ENELGPVGPGKDMEPHSPSLPKEEEPPTPGSA-KMPPAEYRLCNGSEKESMSPTARVSKK XP_004852188.1/1-883 ENELCPVSPGKDMEPHGPLLPREEEPPTPGSATKVPPAEYRLCNGSDKECVSPTARVSKK :*** *: **:***.:.* *::* * **.** *:* *********:**. ***:**:** ENSP00000263650/1-879 ETLKAQKENYRQEKKRATRQLLSALTDPSVVIMADSLKIRGTLKSWTKLWCVLKPGVLLI ENSMUSP00000020411/1-898 DALKAQKENYRQEKKRATKQLFSALTDPSVVIMADSLKIRGTLKSWTKLWCVLKPGVLLI ENSRNOP00000028119/1-898 DTLKAQKENYRQEKKRATKQLFSALTDPSVVIMADSLKIRGTLKSWTKLWCVLKPGVLLI ENSCPOP00000013549/1-880 ETLKAQKENYRQEKKRATKQLFSALTDPSVVIMADSLKIRGTLKSWTKLWCVLKPGVLLI XP_004852188.1/1-883 ETLKAQKENYRQEKKRATKQLFSALTDPSVVIMADSLKIRGTLKSWTKLWCVLKPGVLLI ::****************:**:************************************** ENSP00000263650/1-879 YKTPKVGQWVGTVLLHCCELIERPSKKDGFCFKLFHPLDQSVWAVKGPKGESVGSITQPL ENSMUSP00000020411/1-898 YKTPKVGQWVGTVLLHCCELIERPSKKDGFCFKLFHPLDQSVWAVKGPKGESVGSITQPL ENSRNOP00000028119/1-898 YKTPKVGQWVGTVLLHCCELIERPSKKDGFCFKLFHPLDQSVWAVKGPKGETVGSITQPL ENSCPOP00000013549/1-880 YKTPKVGQWVGTVLLHCCELIERPSKKDGFCFKLFHPLDQSVWAVKGPKGESVGSITQPL XP_004852188.1/1-883 YKTPKVGQWVGTVLLHCCELIERPSKKDGFCFKLFHPLDQSIWAMKGPKGESVGSITQPL *****************************************:**:******:******** ENSP00000263650/1-879 PSSYLIFRAASESDGRCWLDALELALRCSSLLRLGTCKPGRDGEP--GTSPDASPSSLCG ENSMUSP00000020411/1-898 PSSYLIFRAASESDGRCWLDALELALRCSSLLRLSTCKQGRDGEQ--GSSPDASPSSLYG ENSRNOP00000028119/1-898 PSSYLIFRAASESDGRCWLDALELALRCSSLLRLSTCKQGRDGEQ--GSSPDASPSSLYG ENSCPOP00000013549/1-880 PSSYLIFRAASESDGRCWLDALELALRCSSLLRLSSCKQGRDGEP--GSSPDASPSSVYG XP_004852188.1/1-883 PSSYLIFRAASESDGRCWLDALELALRCSSLLRLSSCKQSRDGEPEPGSSPDGSPSSVYG **********************************.:** .**** *:***.****: * ENSP00000263650/1-879 LPASATVHPDQDLFPLNGSSL----ENDAFSDKSERENPEESDTETQDHSRKT-ESGSDQ ENSMUSP00000020411/1-898 LPTSATI-PDQDLFPLNGSAL----ENDAFSDKSERENAEDSDAETQDHSRKTNESGSDL ENSRNOP00000028119/1-898 LPTSATI-PDQDLFPLNGSAL----ENDAFSDKSERENADDSDAETQDHSRKTNESGSDL ENSCPOP00000013549/1-880 LPASVAVPPDQDLFPLNGSSLENHLENDGFSDKSERENAEDSDAETQDHSRKTNESGSDQ XP_004852188.1/1-883 LPASVAIHPDQDLFPLNGSSLENHLENDGFSDKSERENAEDSDAETQDLSRKTNESGSDQ **:*.:: ***********:* ***.*********.::**:**** **** ***** ENSP00000263650/1-879 SETPGAPVRRGTTYVEQVQEELGELGEASQVETVSEENKSLMWTLLKQLRPGMDLSRVVL ENSMUSP00000020411/1-898 LDSPGGP-WRGTTYVEQVQEELGELDETSQVETVSEENKSLMWVLLRQLRPGMDLSRVVL ENSRNOP00000028119/1-898 LDSPGGP-RRGTTYVEQVQEELGELDETSQVETVSEENKSLMWVLLRQLRPGMDLSRVVL ENSCPOP00000013549/1-880 SEGPGGP-RRGTTYVEQVQEELGEQGEVSQVETVSEENKNLMWTLLRQLRPGMDLSRVVL XP_004852188.1/1-883 SEGPGGP-RKGTSYVEQVQEELAELGEVSQVETVSEENKNLMWVLLRQLRPGMDLSRVVL : **.* :**:*********.* .*.***********.***.**:************* ENSP00000263650/1-879 PTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRMKLVLRWYLSGFYKKPKGIKKPYN ENSMUSP00000020411/1-898 PTFVLEPRSFLGKLSDYYYHGDLLSRAAAEDDPYCRMKLVLRWYLSGFYKKPKGIKKPYN ENSRNOP00000028119/1-898 PTFVLEPRSFLSKLSDYYYHGDLLSRAAAEDDPYCRIKLVLRWYLSGFYKKPKGIKKPYN ENSCPOP00000013549/1-880 PTFVLEPRSFLNKLSDYYYHADLLSRAAMEDSAYGRIKLVLRWYLSGFYKKPKGIKKPYN XP_004852188.1/1-883 PTFVLEPRSFLNKLSDYYYHADLLSRAAVEDSAYGRIKLVLRWYLSGFYKKPKGIKKPYN ***********.********.******* *:..* *:*********************** ENSP00000263650/1-879 PILGETFRCCWFHPQTDSRTFYIAEQVSHHPPVSAFHVSNRKDGFCISGSITAKSRFYGN ENSMUSP00000020411/1-898 PILGETFRCRWLHPQTNSHTFYIAEQVSHHPPVSAFYVSNRKDGFCMSGSITAKSKFYGN ENSRNOP00000028119/1-898 PILGETFRCCWLHPQTNSHTFYIAEQVSHHPPVSAFYVSNRKDGFCMSGSITAKSKFYGN ENSCPOP00000013549/1-880 PILGETFRCCWLHPQTNSRTFYIAEQVSHHPPVSAFHVSNRKDGFCMSGSITAKSRFYGN XP_004852188.1/1-883 PILGETFRCCWLHPQTNSHTFYIAEQVSHHPPVSAFHISNRKDGFCMSGSITAKSRFYGN ********* *:****:*:*****************::********:********:**** ENSP00000263650/1-879 SLSALLDGKATLTFLNRAEDYTLTMPYAHCKGILYGTMTLELGGKVTIECAKNNFQAQLE ENSMUSP00000020411/1-898 SLSALLDGKAKLTFLNRKEEYTLTMPYAHCRGILYGTMTMELGGKVNIECEKNNLQAELD ENSRNOP00000028119/1-898 SLSALLDGKAKLTFLNRKEEYTLTMPYAHCRGLLYGTMTMELGGKVTIQCEKNNLQAELD ENSCPOP00000013549/1-880 SLSALLDGKATLTFLNRAEDYTLTMPYAHCRGLLYGTMTLELGGKVTIACEKNNLQVELD XP_004852188.1/1-883 SLSALLDGKATLTFLNRAEDYTLTMPYAHCRGLLYGTMTLELGGKVTIACEKNNLQVELD **********.****** *:**********:*:******:******.* * ***:*.:*: ENSP00000263650/1-879 FKLKPFFGGSTSINQISGKITSGEEVLASLSGHWDRDVFIKEEGSGSSALFWTPSGEVRR ENSMUSP00000020411/1-898 FKLKPFFGSSANINQISGKIMSGEEVLARLTGHWDRDVFIKEESSGGTELFWTPSEEVRR ENSRNOP00000028119/1-898 FKLKPFFGSSTSINQISGKITSGEEVLARLTGHWDRDVFIKEEASGGTKLFWTPSEEVRR ENSCPOP00000013549/1-880 FKLKPFFGGSTNINQISGKIMSGEEVLARLTGHWDRDVFIKEEGSGNSELFWTPSEEVRT XP_004852188.1/1-883 FKLKPFFGGSTHINQISGKIMSGEEVLARLTGHWDRDVFIKEEGSGNSELFWTPSKEVQA ********.*: ******** ******* *:************.**.: ****** **: ENSP00000263650/1-879 QRLRQHTVPLEEQTELESERLWQHVTRAISKGDQHRATQEKFALEEAQRQRARERQESLM ENSMUSP00000020411/1-898 QRLKRHTVLLEEQSELESERLWQHVTRAIREGDQHKATQEKSVLEEAQRQRAREHQQSLT ENSRNOP00000028119/1-898 QRLKRHTVLLEEQSELESERLWQHVTRAIHEGDQHKATQEKSVLEEAQRQRAREHQQSLT ENSCPOP00000013549/1-880 QRLKRHTVLFEEQTELESERLWQHVTKAILEGDQHKATQEKFTLEEAQRQRSRERQQNLT XP_004852188.1/1-883 QRLKRHTVLFEEQTELESERLWQHVTRAILEGDQHKATQEKFILEEAQRQRSRERQQNLT ***::*** :***:************:** :****:***** ********:**:*:.* ENSP00000263650/1-879 PWKPQLFHLDPITQEWHYRYEDHSPWDPLKDIAQFEQDGILRTLQQEAVARQTTFLGSPG ENSMUSP00000020411/1-898 PWKPQLFLLDPLTQEWRYRYEDLSPWDPLKDIAQYEQDGILHTLQRETMSGQTTFLGSPD ENSRNOP00000028119/1-898 PWKPQLFTLDPLTQEWRYQYEDYSPWDPLKDIAQYEQDGILHTLQRETMSGQTAFLGSPE ENSCPOP00000013549/1-880 PWKPQLFCLDPLTQEWHYRYENHSPWDPLKDIAQFEQDGVLHTLQRETMARQTTFLGSPG XP_004852188.1/1-883 PWKPQLFHLDPLTQEWRYRYENHRPWDPLKDIAQFEQDGVLHTLERETMAHQTTFLGSPG ******* ***:****:*:**: **********:****:*:**::*::: **:***** ENSP00000263650/1-879 PRHERSGPDQRLRKASDQPSGHSQATESSGSTPESCPELSDEEQDGDFVPGGESPCPRCR ENSMUSP00000020411/1-898 SRHKRPSSDRRLRKASDQPSGHSQVTESSGSTPESCPDLSDE----DFVPGGESPCPRCR ENSRNOP00000028119/1-898 SRHKRPSSDRRLRKASDQPSGHSQVTESSGSTPESCPDLSDE----DFVPGNESPCPRCR ENSCPOP00000013549/1-880 SRHERPGPDRRLRKASDQPSGHSQVTESSGSTPESCPELSDE--DGDFVPGSESPCPRCR XP_004852188.1/1-883 SGHKRPGPDRRLRKASDQPSGHSQVTESSGSTPESCPELSDE--DGDFVPGSDSPCPRCR . *:*...*:**************.************:**** *****.:******* ENSP00000263650/1-879 KEARRLQALHEAILSIREAQQELHRHLSAMLSSTARAAQAPTPGLLQSPRSWFLLCVFLA ENSMUSP00000020411/1-898 REVHRLKMLQEAVLSIQEAQQELHRHLSTMLSSTVRAGQAPAPSLLQNPRSWFLLCIFLT ENSRNOP00000028119/1-898 REVHRLRMLQEAVLSIQEAQQELHRHLSAMLRSTVRAGQAPAPGLLQNPRSWFLLCIFLT ENSCPOP00000013549/1-880 REVHRLQALQEAVLSIKEAQQELHRHLSAMLSCAVQARQAPPPGLLHSPRSWFLLCVFLA XP_004852188.1/1-883 REVHRLQALQEAVLSIQEAQQELHRHLSAMLSCAVRTRQAPPSGLLHRPHSWFLLCVFLA :*.:**: *:**:***:***********:** .:.:: ***...**: *:******:**: ENSP00000263650/1-879 CQLFINHILK ENSMUSP00000020411/1-898 CQLFINYILK ENSRNOP00000028119/1-898 CQLFINYILK ENSCPOP00000013549/1-880 CQLLINYVLK XP_004852188.1/1-883 CQLLINYALK ***:**: **