CLUSTAL W(1.81) multiple sequence alignment ENSMUSP00000080489/1-1050 MGSAEDAVKEKLLWNVKKEVKQIMEEAVTRKFVHEDSSHIIALCGAVEACLLHQLRRRAA ENSRNOP00000032080/1-1005 MGSAEDAVKEKLLWNVKKEVKQIMEEAVTRKFVHEDSSHIIALCGAVEACLLHQLRRRAA ENSP00000268989/1-1051 MGSAEDAVKEKLLWNVKKEVKQIMEEAVTRKFVHEDSSHIIALCGAVEACLLHQLRRRAA XP_004857236.1/1-1051 MGSAENAVKEKLLWNVKKEVKQIMEEAVTRKFVHEDSSHIIALCGAVEACLLHQLKRRAA ENSCPOP00000013369/1-1039 ------------MLSICPQVKQIMEEAVTRKFVHEDSSHIIALCGAVEACLLHQLKRRAA : .: :************************************:**** ENSMUSP00000080489/1-1050 GFLRSDKMAALFTKVGKTCPVAEDICHKVQELQQQAEGRKPSGGSQEALRKQGSTGGKAP ENSRNOP00000032080/1-1005 GFLRSDKMAALFTKVGKTCPVAGDICHKVQELQQQAEGRRPSGGSQEALRKQGSSSGKTT ENSP00000268989/1-1051 GFLRSDKMAALFTKVGKTCPVAGEICHKVQELQQQAEGRKPSGVSQEALRRQGSASGKAP XP_004857236.1/1-1051 GFLRSDKMAALFTKVGKTCPVAGEICHKVQELQQQVEGRTPSGASQEALRRQGSTSGKAP ENSCPOP00000013369/1-1039 GFLRSDKMAALFTKVGKTCPVAGEICHKVQELQQQVEGRKPSGGNQEALRRQGSASGKAS ********************** :***********.*** *** .*****:***:.**:. ENSMUSP00000080489/1-1050 ALSPQALKHIWVRTALMEKVLDRVVQYLAENCSKYYEKEALLADPVFGPILACLLVGPCA ENSRNOP00000032080/1-1005 ALSPQALKHIWVRTALMEKVLDRVVQYLAENCSKYYEKEALLADPVFGPILACLLVGPCA ENSP00000268989/1-1051 ALSPQALKHVWVRTALIEKVLDKVVQYLAENCSKYYEKEALLADPVFGPILASLLVGPCA XP_004857236.1/1-1051 ALSPQALKHIWVRTALIEKVLDRVVQYLAENCSKFYEKEALLADPVFGPILASLLVGPCA ENSCPOP00000013369/1-1039 ALSPQALKHIWVRTALIEKVLDRVVQYLAENCSKFYEKEALLADPVFGPILASLLVGPCA *********:******:*****:***********:*****************.******* ENSMUSP00000080489/1-1050 LEYTKLKTADHYWTDPSADELVQRHRIRGPPNRQDSPAKRPALGIRKRHSSGSASEDRLA ENSRNOP00000032080/1-1005 LEYTKLKTADHYWTDPSADELVQRHRIRGPPNRQDSPAKRPALGIRKRHSSGSASEDRLA ENSP00000268989/1-1051 LEYTKLKTADHYWTDPSADELVQRHRIRGPPTRQDSPAKRPALGIRKRHSSGSASEDRLA XP_004857236.1/1-1051 LEYTKLKTADHYWTDPSADELVQRHRIRGPPNRQDSPAKRPALGIQKRHSSGSASEDRLA ENSCPOP00000013369/1-1039 LEYTKLKTADHYWTDPSADELVQRHRIRGPPNRQDSPAKRPALGIRKRHSSGSASEDRLA *******************************.*************:************** ENSMUSP00000080489/1-1050 ACAREYVESLHQNSRTRLLYGKNNVLVQPKEDMEAVPGYLSLHQSAENLTLKWTPNQLMN ENSRNOP00000032080/1-1005 ACAREYVESLHQNSRTRLLYGKNNVLVQPKEDMEAVPGYLSLHQSAENLTLKWTPNQLMN ENSP00000268989/1-1051 ACARECVESLHQNSRTRLLYGKNHVLVQPKEDMEAVPGYLSLHQSAESLTLKWTPNQLMN XP_004857236.1/1-1051 ACARDYVESLHQNSRMRLLYGKNNVLVQPKEDMEAVPGYLSLHQSAESLTLKWTPNQLMN ENSCPOP00000013369/1-1039 AWAREYVESLHQNSRTRLLYGKNNVLVQPKEDMEAVPGYLSLHQSAESLTLKWTPNQLMN * **: ********* *******:***********************.************ ENSMUSP00000080489/1-1050 GTLGDSELEKSVYWDYALVVPFSQIVCIHCHQQKSGGTLVLVSQDGIQRPPLHFPQGGHL ENSRNOP00000032080/1-1005 GTLGDSELEKSVYWDYALVVPFSQIVCVHCHQQKSGGTLVLVSQDGIQRPPLHFPQGGHL ENSP00000268989/1-1051 GTLGDSELEKSVYWDYALVVPFSQVVCIHCHQQKSGGTLVLVSQDGIQRPPLHFPQGGHL XP_004857236.1/1-1051 GTLGDSELEKSVYWDYALLVPFSQIVCIHCHQQKSGGTLVLVSQDGIQRPPLHFPQGGHL ENSCPOP00000013369/1-1039 GTLGDSELEKSVYWDYALVVPFSQIVCIHCHQQKNGGTLVLVSQDGIQRPPLHFPQGGHL ******************:*****:**:******.************************* ENSMUSP00000080489/1-1050 LSFLSCLENGLLPRGQLEPPLWTQQGKGKVFPKLRKRSSIRSIDVEELGVGRATDYVFRI ENSRNOP00000032080/1-1005 LSFLSCLENGLLPRGQLEPPLWTQQGKGKVFPKLRKRSSIRSIDAEELGVGRATDYVFRI ENSP00000268989/1-1051 LSFLSCLENGLLPRGQLEPPLWTQQGKGKVFPKLRKRSSIRSVDMEEMGTGRATDYVFRI XP_004857236.1/1-1051 LSFLSCLENGLLPRGQLEPPLWTQQGKGKVFPKLRKRSSMQSVDVEELGMGQATDYVFRI ENSCPOP00000013369/1-1039 LSFLSCLENGLLPRGQLEPPLWTQQGKGKVFPKLRKRSSMRSVDVEELGMGRATDYVFRI ***************************************::*:* **:* *:******** ENSMUSP00000080489/1-1050 IYPGHRHEHITINYHHLAASRAASVDDDEEEEDKLHAMLSMICSRNLTAPNPMKDAGDMI ENSRNOP00000032080/1-1005 IYPGHRHEH---------------------------------------------NAGDMI ENSP00000268989/1-1051 IYPGHRHEHITINYHHLAASRAASVDDDEEEEDKLHAMLSMICSRNLTAPNPMKDAGDMI XP_004857236.1/1-1051 IYPGHKHEHITINYHHLAASRAASVDDDEEEEDKLHAMLSMICSRNLTAPNPMKDAGDMI ENSCPOP00000013369/1-1039 IYPGHKHEHITINYHHLAASRAASVDDDEEEEDKLHAMLSMICSRNLTAPNPMKDAGDMI *****:*** :***** ENSMUSP00000080489/1-1050 EMQGFGPSLTAWHLEPLCSQGSSCLSCSSSSSPYATPSHCSCIPDRLPLRLLCESMKRQI ENSRNOP00000032080/1-1005 EMQGFGPSLTAWHLEPLCSQGSSCLSCPSSSSPYAPPSHCSCTPDRLPLRLLCESMKRQI ENSP00000268989/1-1051 EMQGFGPSLPAWHLEPLCSQGSSCLSCSSSSSPHATPSHCSCIPDRLPLRLLCESMKRQI XP_004857236.1/1-1051 EMQGFGPGLAAWHLEPLCSQGSSCLSCSSRSSPYATPSHCSCIPDRLPLRLLCESMKRQI ENSCPOP00000013369/1-1039 EMQGFGPGLAAWHLEPLCSQGSSCLSCSSCSSPYATSSHCSCILDRLPLRLLCESMKRQI *******.*.*****************.* ***:*..***** **************** ENSMUSP00000080489/1-1050 VSRAFYGWLAYCRHLSTVRTHLSALVHHNIIPPDRPPGASGGLTKDVWSKYQKDEKNYKE ENSRNOP00000032080/1-1005 VSRAFYGWLAYCRHLSTVRTHLSALVHHNIIPPDRPPGASGGLTKDVWSKYQKDKKNYKE ENSP00000268989/1-1051 VSRAFYGWLAHCRHLSTVRTHLSALVHHSVIPPDRPPGASAGLTKDVWSKYQKDKKNYKE XP_004857236.1/1-1051 VSRAFYGWLAYCRHLSTVRTHLSALVHHNIIPPDRPPGASGGLTKDVWSKYQKDKKNYKE ENSCPOP00000013369/1-1039 VSRAFYGWLAYCRHLSTVRTHLSALVRHNIIPPDQPPGASRGLTKDVWSKYQKDKKNYKE **********:***************:*.:****:***** *************:***** ENSMUSP00000080489/1-1050 LELLRQVYYGGVEHEIRKDVWPFLLGHYKFGMSKKEMEQVDTAVAARYQQVLAEWKACEV ENSRNOP00000032080/1-1005 LELLRQVYYGGVEHEIRKDVWPFLLGHYKFGMSKKEMEQVDAAVAARYQQVLAEWKACEV ENSP00000268989/1-1051 LELLRQVYYGGIEHEIRKDVWPFLLGHYKFGMSKKEMEQVDAVVAARYQQVLAEWKACEV XP_004857236.1/1-1051 LELLRQVYYGGVEHEIRKNVWPFLLGHYKFGMNKKEMEQVDAAVATRYQQVLAEWKACEV ENSCPOP00000013369/1-1039 LELLRRVYYGGVEHEIRKDIWPFLLGHYKFGMNKKEMEQVDAAVAARYQQVLTEWKACEV *****:*****:******::************.********:.**:******:******* ENSMUSP00000080489/1-1050 VVRQREREAHPATLTKFSSGSSIDSHVQRLVHRDSTISNDVFISVDDLEPSGPQDLEDSK ENSRNOP00000032080/1-1005 VVRQREREAHPATLTKFSSGSSIDSHVQRLVHRDSTISNDVFISVDDLEPPGPQDPEDSK ENSP00000268989/1-1051 VVRQREREAHPATRTKFSSGSSIDSHVQRLIHRDSTISNDVFISVDDLEPPEPQDPEDSR XP_004857236.1/1-1051 VVRQREQEAHPSTFTKFSSGSSIDSHVQHLIHRDSTISNDVFISVDDLETPGPQASEDAR ENSCPOP00000013369/1-1039 VVRQREREAHPAALTKFSSGSSIDSHVQRLIHRDSTISNDVFISVDDLETPGPQASEDTR ******:****:: **************:*:******************.. ** **:: ENSMUSP00000080489/1-1050 PKREQEPGAGTPGIAAAEQQ-SVEFDSPDSGLPSSRNYSVASGIQSSLDEAQSVGF-EDD ENSRNOP00000032080/1-1005 PKQEREPGAGTPGTAAAEQQ-SVEFESPDSGLPSSRNYSVASGIQSSLDEAQSVGF-EED ENSP00000268989/1-1051 PKPEQEAGPGTPGTAVVEQQHSVEFDSPDSGLPSSRNYSVASGIQSSLDEGQSVGFEEED XP_004857236.1/1-1051 PKPEQEPGVGTPDNAMVEQQQSVEFDSPDSGLPSSRNYSVASGIQSSLDEGQSVGF-EED ENSCPOP00000013369/1-1039 PNPEQEPGVGTPGTAMVEQQQSVEFDSPDSGLPSSRNYSVASGIQSSLDEGQSVGF-EED *: *:*.* ***. * .*** ****:************************.***** *:* ENSMUSP00000080489/1-1050 GAGEDGSEGPATAAHTFPGPHDPGQETLAPASELEAGQELAAVCAAAYTIELLDTVALNL ENSRNOP00000032080/1-1005 GAGEEGSEEPATAAHTFLGPHDPDQEKLAPASELEGGEELTAVCAATYTIELLDTVALNL ENSP00000268989/1-1051 GGGEEGSSGPGPAAHTLREPQDPSQEK-PQAGELEAGEELAAVCAAAYTIELLDTVALNL XP_004857236.1/1-1051 GGGEEGSGGLTSAAHSFSEPRDPSQEKASQASELEAGGELAAVCAASYTIELLDTVALNL ENSCPOP00000013369/1-1039 GGGEEGSNELASAAHAFSEPQEPSQEKALQASELEADGELAAMCAAAYTIELLDTVALNL *.**:** .***:: *::*.**. *.***.. **:*:***:************* ENSMUSP00000080489/1-1050 HRIDKDVQRCDRNYWYFTTSNLERLRDIMCSYVWEHLDMGYVQGMCDLLAPLLVILDNDQ ENSRNOP00000032080/1-1005 HRIDKDVQRCDRNYWYFTTPNLERLRDIMCSYVWEHLDMGYVQGMCDLLAPLLVILDNDQ ENSP00000268989/1-1051 HRIDKDVQRCDRNYWYFTPPNLERLRDVMCSYVWEHLDVGYVQGMCDLLAPLLVTLDNDQ XP_004857236.1/1-1051 HRIDKDVQRCDRNYWYFSLPNLERLRDIMCSYVWEHLDMGYVQGMCDLLAPLLVILDNDQ ENSCPOP00000013369/1-1039 HRIDKDVQRCDRNYWYFTPPNLERLRDIMCSYVWEHLDMGYVQGMCDLLAPLLVILDDDQ *****************: .*******:**********:*************** **:** ENSMUSP00000080489/1-1050 LAYSCFSHLMKRMGQNFPSGGAMDSHFANMRSLIQILDSELFELMHQNGDYTHFYFCYRW ENSRNOP00000032080/1-1005 LAYSCFSHLMKRMSQNFPNGGAMDTHFANMRSLIQILDSELFELMHQNGDYTHFYFCYRW ENSP00000268989/1-1051 LAYSCFSHLMKRMSQNFPNGGAMDTHFANMRSLIQILDSELFELMHQNGDYTHFYFCYRW XP_004857236.1/1-1051 LAYSCFSHLMKRMSQNFPNGGAMDTHFANMRSLIQILDSELFELMHQNGDYTHFYFCYRW ENSCPOP00000013369/1-1039 LAYSCFSHLMKRMSQNFPSGGAMDTHFANMRSLIQILDSELFELMHQNGDYTHFYFCYRW *************.****.*****:*********************************** ENSMUSP00000080489/1-1050 FLLDFKRELLYEDVFAVWEVIWAARRISSEHFVLFIALALVEAYREIIRDNNMDFTDIIK ENSRNOP00000032080/1-1005 FLLDFKRELLYEEVFAVWEVIWAARHISSEHFVLFIALALVEAYREIIRDNNMDFTDIIK ENSP00000268989/1-1051 FLLDFKRELLYEDVFAVWEVIWAARHISSEHFVLFIALALVEAYREIIRDNNMDFTDIIK XP_004857236.1/1-1051 FLLDFKRELLYEDVFAVWEVIWAARCISSEHFVLFIALALVEAYREIIRDNNMDFTDIIK ENSCPOP00000013369/1-1039 FLLDFKRELLYEDVFAVWEVIWAARHISSEHFVLFIALALVEAYREIIRDNNMDFTDIIK ************:************ ********************************** ENSMUSP00000080489/1-1050 FFNERAERHDAQEILRIARDLVHKVQMLIDNK ENSRNOP00000032080/1-1005 FFNERAERHDAQEILRIARDLVHKVQMLIDNK ENSP00000268989/1-1051 FFNERAEHHDAQEILRIARDLVHKVQMLIENK XP_004857236.1/1-1051 FFNERAEHHDAQEILRIARDLVHKVQMLIENK ENSCPOP00000013369/1-1039 FFNERAERHDAQEILRIARDLVHKVQMLIENK *******:*********************:**