CLUSTAL W(1.81) multiple sequence alignment ENSMUSP00000104280/1-982 -MPPPAEVTDPSHAPAVLHQLNEQRLRGLFCDVTLIAGDTKFPAHRSVLAASSPFFREAL ENSRNOP00000019687/1-984 -MPPPAEVTDPSHAPAVLRQLNEQRLRGLFCDVTLIAGDTKFPAHRSVLAASSPFFREAL ENSP00000369973/1-1013 -MPPPAEVTDPSHAPAVLRQLNEQRLRGLFCDVTLIAGDTKFPAHRSVLAASSPFFREAL ENSCPOP00000013345/1-917 AMPSPAEVTDPSHAPAVLRQLNEQRLRGLFCDVTLIAGDTKFPAHRSVLAASSPFFREAL XP_004857482.1/1-994 -MPPPAEVTDPSHAPAVLRQLNEQRLRGLFCDVTLIAGDTKFPAHRSVLAASSPFFREAL **.**************:***************************************** ENSMUSP00000104280/1-982 LASAPLPLPPVTGGSAPSPATTTAA---------------------SSSSSSPPPASPHS ENSRNOP00000019687/1-984 LASAPLPLPPVTGGSAPSPATTTAA---------------------SSSSSPPPPASPHS ENSP00000369973/1-1013 LTSAPLPLPPATGGAAPNPATTTAASSSSSSSSSSSSSSSSASSSSSSSSSSPPPASPPA ENSCPOP00000013345/1-917 LASAPLPLPPVTGGSAPNPLTTTAA----------------------------------- XP_004857482.1/1-994 LASAPLPLPPVTGGSAPNPLTTTAA-------------------SSSSSSSSPSPASAPA *:********.***:**.* ***** ENSMUSP00000104280/1-982 SSPPRVLELPGVPAAAFSDVLNFIYSARLALPGGGGDGAAVAEIGALGRRLGISRLQGLG ENSRNOP00000019687/1-984 SSPPRVLELPGVPAAAFSDVLNFIYSARLALPGGGGDGAAVAEIGALGRRLGISRLQGLG ENSP00000369973/1-1013 SSPPRVLELPGVPAAAFSDVLNFIYSARLALPGGGGDGAAVAEIGALGRRLGISRLQGLG ENSCPOP00000013345/1-917 SSPPRVLELPGVPAAAFSDVLNFIYSARLALPGGGGDGAAVAEIGALGRRLGISRLQGLG XP_004857482.1/1-994 SSPPRVLELPGVPAAAFSDVLNFIYSARLALPGGGGDGAAVAEIGALGRRLGISRLQGLG ************************************************************ ENSMUSP00000104280/1-982 EGGDTWVPPAPTSMVTSDPTEDGLGAGPRTDGEWVGDKAEALTPDSQ---PRRPFPCPRC ENSRNOP00000019687/1-984 EGGDTWVPPAPSSMVTSEPNEDSLGPGLRTDGGWEGDKAEPLTPDSQ---PRRPFPCPRC ENSP00000369973/1-1013 EGGDAWVPPTPAPMATSQPEEDSFGPGPRPAGEWEGDRAEAQAPDLQCSLPRRPLPCPQC ENSCPOP00000013345/1-917 EGGDAWVPPTPAPMASSQPEEDGFGPGPRPDGEWDGDRAEAQAAGSQPSLPRRPLPCPQC XP_004857482.1/1-994 EGGDSWVPPTPAPMASSQPEEDSFGPGPRPDGEWEGDRAEAQAPDSQPSLPRRPLPCPQC ****:****:*:.*.:*:* **.:*.* *. * * **:**. :.. * ****:***:* ENSMUSP00000104280/1-982 GKSFIHPKRLQTHEAQCRRGSNTRGSAGLGPGVSGSGGPAGVDASALPQPVGFRDGPEHV ENSRNOP00000019687/1-984 GKSFIHPKRLQTHEAQCRRGSNTRGSAGLGPGGSGPGGPAGVDASALPQPVSFRDGPEHV ENSP00000369973/1-1013 GKSFIHPKRLQTHEAQCRRGASTRGSTGLGAGGAGPGGPAGVDASALPPPVGFRGGPEHV ENSCPOP00000013345/1-917 GKSFIHPKRLQTHEAQCRRGTSTRGSAGLGTGGSGPGGPAGVDASALPPTVGFRGGPEHV XP_004857482.1/1-994 GKSFIHPKRLQTHEAQCRRGASTRGSAGLGTGGSGPGGPAGVDASALPTTVGFRGGPEHV ********************:.****:***.* :*.************ .*.**.***** ENSMUSP00000104280/1-982 VKVVGGHVLYVCAACERSYVTLSSLKRHSNVHSWRRKYPCRYCEKVFALAEYRTKHEVWH ENSRNOP00000019687/1-984 VKVVGGHVLYVCAACERSYVTLSSLKRHSNVHSWRRKYPCRYCEKVFALAEYRTKHEVWH ENSP00000369973/1-1013 VKVVGGHVLYVCAACERSYVTLSSLKRHSNVHSWRRKYPCRYCEKVFALAEYRTKHEVWH ENSCPOP00000013345/1-917 VKVVGGHVLYVCAACERSYVTLSSLKRHSNVHSWRRKYPCRYCEKVFALAEYRTKHEVWH XP_004857482.1/1-994 VKVVGGHVLYVCAACERSYVTLSSLKRHSNVHSWRRKYPCRYCEKVFALAEYRTKHEVWH ************************************************************ ENSMUSP00000104280/1-982 TGERRYQCIFCWDTFVTYYNLKTHQRAFHGISPGLLASEKTPNGGYKPRLNTLKLYRLLP ENSRNOP00000019687/1-984 TGERRYQCIFCWETFVTYYNLKTHQRAFHGISPGLLASEKTPNGGYKPKLNTLKLYRLLP ENSP00000369973/1-1013 TGERRYQCIFCWETFVTYYNLKTHQRAFHGISPGLLASEKTPNGGYKPKLNTLKLYRLLP ENSCPOP00000013345/1-917 TGERRYQCIFCWETFVTYYNLKTHQRAFHGISPGLLASEKTPNGGYKPKLNTLKLYRLLP XP_004857482.1/1-994 TGERRYQCIFCWETFVTYYNLKTHQRAFHGISPGLLASEKTPNGGYKPKLNTLKLYRLLP ************:***********************************:*********** ENSMUSP00000104280/1-982 MRAAKRPYKTYSQGAPEAPLSPSLHTPAPAAMPASPQPLPPPAPEPGPPPSVITFAHPAP ENSRNOP00000019687/1-984 MRAAKRPYKTYSQGAPEAPLSPSLHTPVPAVMPASPQPLLPSVPEPGPPHSVITFAHPAP ENSP00000369973/1-1013 MRAAKRPYKTYSQGAPEAPLSPTLNTPAPVAMPASPPPGPPPAPEPGPPPSVITFAHPAP ENSCPOP00000013345/1-917 MRAAKRPYKTYSQGAPDAPLSPGLHTPAAAALPAS---------------SVITFAHPAP XP_004857482.1/1-994 MRAAKRPYKTYSQGPPDAPLSPSLHTPAPAAMPASPPPVPPPAPEPGPPPSVITFAHPAP **************.*:***** *:**....:*** ********** ENSMUSP00000104280/1-982 SVIVHGSSSSGA-AGGGPAGTGGSQAASVITYTTPPRPPKKREYPPPPPEPTATPTSPAS ENSRNOP00000019687/1-984 SVIVHGSSSSGA-AGGGPVGTGGSQAASVITYTTPPRPPKKREYPPPPPEPAATPTSPAS ENSP00000369973/1-1013 SVIVHGGSSSGG-GGSGTASTGGSQAASVITYTAPPRPPKKREYPPPPPEPAATPTS-PA ENSCPOP00000013345/1-917 SVIVHGSNSVGGAGGGGATSTGGSQAASVITYTAPPRPPKKREYPPPPPEPAATPTS-PA XP_004857482.1/1-994 SVIVHGGSSSGG-TGGGPTSTGGSQAASVITYTAPPRPPKKREYPPPPPGPAAIPISPPT ******..* *. *.*...*************:*************** *:* * * .: ENSMUSP00000104280/1-982 TAVSPATAAGP--ATATEEAKGRNLRAGRTLTYTAKPVGGLSGSGGSPTGTGRGSSQLQA ENSRNOP00000019687/1-984 TAVIPATAAGP--ATATEEAKGRNLRAGRTLTYTAKPVGGVSGSGGSPTGTGRGSSQLQA ENSP00000369973/1-1013 TAVSPATAAGPAMATTTEEAKGRNPRAGRTLTYTAKPVGGIGGGGGPPTGAGRGPSQLQA ENSCPOP00000013345/1-917 TIISPATAAGP--ATAMEEAKGRNPRAGRTLTYTAKPVGSIGGSGGPPSGPGRGPAHLQA XP_004857482.1/1-994 TTISPATAAGP--ATAMEEAKGRNPRAGRILTYTAKPVGGIGGGGGPPTGPGRGPSQLQA * : ******* **: ******* **** *********.:.*.**.*:*.***.::*** ENSMUSP00000104280/1-982 PPPLCQITVRIGEEAIVKRRISETDLRPGELSGEEVEESEEEEEEEEEEDQEEQEE--SK ENSRNOP00000019687/1-984 PPPLCQITVRIGEEAIVKRRISETDLRPGELSGEEVEESEEEEEEEEEEDQEDQEE--SK ENSP00000369973/1-1013 PPPLCQITVRIGEEAIVKRRISETDLRPGELSGEEMEESEEDEEEEDEEEEEEDEEE-SK ENSCPOP00000013345/1-917 PPPLCQITVRIGEEAIVKRRISETDLRP------------------------------AK XP_004857482.1/1-994 PPPLCQITVRIGEEAIVKRRISETDLRPGELSGEELEESEEEDEEEEEDDDDEEEDEESK **************************** :* ENSMUSP00000104280/1-982 AGGEDQLWRPYYSYKPKRKAGATAGGASGVSGLPRGRRPPRWRQKLERRGWEETPSVEGP ENSRNOP00000019687/1-984 AGGEDQLWRPYYSYKPKRKAGAT---ASGLSGLPRGRRPPRWRQKLERRGWEETPAVEGP ENSP00000369973/1-1013 AGGEDQLWRPYYSYKPKRKAGAAGGASVGGSGLPRGRRPPRWRQKLERRSWEETPAAESP ENSCPOP00000013345/1-917 AGGEDQLWRPYYSYKPKRKAGTANGGGGGAGVIPRGRRPTRWRQKLERRGWEETPAAESP XP_004857482.1/1-994 AGGADQLWRPYYSYKPKRKAGAASGGVGGTGGMPRGRRATRWRQKVERRGWEETPALESP *** *****************:: * . :*****..*****:***.*****: *.* ENSMUSP00000104280/1-982 GGRGRGERRHRCGDCAQAFATVRKLRKHQEAHSGGSHTSRTGRRSSTRFTCPHCAKVCKT ENSRNOP00000019687/1-984 GGRGRGERRHRCGDCAQAFATLRKLRKHQEAHSGGSHNSRTGRRSSTRFTCPHCAKVCKT ENSP00000369973/1-1013 AGRARTERRHRCGDCAQTFTTLRKLRKHQEAHGGGSHSSRAGRRPSTRFTCPHCAKVCKT ENSCPOP00000013345/1-917 AGRARSERAHRCGDCGQTFATYRKLQKHQEAHSGGSHGSRAGRRASTRFTCPQCTKVCKT XP_004857482.1/1-994 AGRARSERRHRCGDCAQTFATLRKLRKHQEAHSGGSHSSRAGRRPSNRFTCPHCGKVCKT .**.* ** ******.*:*:* ***:******.**** **:***.*.*****:* ***** ENSMUSP00000104280/1-982 AAALNRHGQRHAVERPGGTPTPVIAYSKGSIGTRPTDVKEEAPQEMQVSSSSGEAGSGS- ENSRNOP00000019687/1-984 AAALNRHGQRHAVERPGGTPTPVIAYSKGSIGTRPTDVKEEAPQEMQVSSSSGEAGGGSA ENSP00000369973/1-1013 AAALSRHGQRHAAERPGGTPTPVIAYSKGSAGTRPGDVKEEAPQEMQVSSSSGEAGGGS- ENSCPOP00000013345/1-917 AAALSRHGQRHAAERPGGTPTPVIAYSKGSTGTRPGDVKEEAPQEMQVSSSSGEAGGGS- XP_004857482.1/1-994 AAALSRHGQRHAAERPGGTPTPVIAYSKGSTGTRPGDVKEEAPQEMQVSSSSGEAGGGS- ****.*******.***************** **** ********************.** ENSMUSP00000104280/1-982 -AAAAEASESASLQDPVISGGEEPP-VAGGGSYVYPPVQEFPLALIGGSREPSAGKGKPG ENSRNOP00000019687/1-984 AAAAAEASESASLQDPVISGGEEPP-VAGGGGYVYPPVQEFPLALIGGSRDPGAGKGKPG ENSP00000369973/1-1013 -TAAEEASETASLQDPIISGGEEPPVVASGGSYVYPPVQEFPLALIGGGREPGGGRGKSG ENSCPOP00000013345/1-917 -AAAEEASDTASLQDPVISGGEEPP-VPGVASYVYPPVQEFPLALIGGGREPGGGRGKPG XP_004857482.1/1-994 -AAAEGASETASLQDPVISGGEEPP-VAGVGSYVYPPVQEFPLALIGGSREPGGGRGKPG :** **::******:******** *.. ..****************.*:*..*:**.* ENSMUSP00000104280/1-982 NEGSLGAS-EGDRMEGMGTAKVTFYPEPYPLVYGPQLLAAYPYNFSNLAALPVALNMVLP ENSRNOP00000019687/1-984 NEGPVGAS-EGNRMEEMGTAKVTFYPEPYPLVYGPQLLAAYPYNFSNLAALPVALNMVLP ENSP00000369973/1-1013 SEGPVGAG-EGDRMEGIGAAKVTFYPEPYPLVYGPQLLAAYPYNFSNLAALPVALNMVLP ENSCPOP00000013345/1-917 SEGPAGVP-EGDRIEGLGAAKVTFYPEPYPLVYGPQLLAAYPYNFSNLAALPVALNMVLP XP_004857482.1/1-994 SEGTVGGGSEGDRMEGMGAAKVTFYPEPYPLVYGPQLLAAYPYNFSNLAALPVALNMVLP .**. * **:*:* :*:***************************************** ENSMUSP00000104280/1-982 DEKGGGALPFLPGVFGYAVNPQAA----PPTPPPP-LPLPVSPKGIGGMTGVERTQKGDV ENSRNOP00000019687/1-984 DEKGGGALPFLPGVFGYAVNPQTA-PPTPPTPPPP-LPLPVPPKGVGEMTGVERTQKGDV ENSP00000369973/1-1013 DEKGAGALPFLPGVFGYAVNPQAA-PPAPPTPPPPTLPPPIPPKGEGERAGVERTQKGDV ENSCPOP00000013345/1-917 DEKGGGALPFLPGVFGYTVNPQAQMPPSLDLPPPPAPWPPCPS----------------- XP_004857482.1/1-994 DEKGGGALPFLPGVFGYTVNPQAT-PSTPPTPPPPTLPPPVPPKGEGERAGVERTQKGDV ****.************:****: **** * .. ENSMUSP00000104280/1-982 G ENSRNOP00000019687/1-984 G ENSP00000369973/1-1013 G ENSCPOP00000013345/1-917 G XP_004857482.1/1-994 G *