CLUSTAL W(1.81) multiple sequence alignment ENSP00000379174/1-508 MLPKR-RRARVGSPSGDAASSTPPS-TRFPGVAIYLVEPRMGRSRRAFLTGLARSKGFRV ENSMUSP00000105463/1-511 MLPKR-RRVRAGSPHSAVASSTPPSVVRFPDVAIYLAEPRMGRSRRAFLTRLARSKGFRV ENSRNOP00000018320/1-495 MLPKRRRRVRAGSPHSALASSTPPA-ARFPGVAIYLAEPRMGRSRRAFLTRLARSKGFRI ENSCPOP00000013323/1-489 MLPKR-RRARARSPGAAAACSTPSS-VLFPDVAIYLAEPRMGRSRRSFLTRLALSKGFRV XP_004839985.1/1-493 MLPKR-RRVRARSPGGPAASSTSSS-ALFPGVAIYLAEPRMGRSRRAFLTRLAMSKGFRV ***** **.*. ** . *.**..: . **.*****.*********:*** ** *****: ENSP00000379174/1-508 LDACSSEATHVVMEETSAEEAVSWQERRMAAAPPGCTPPALLDISWLTESLGAGQPVPVE ENSMUSP00000105463/1-511 LDAYSSKVTHVVMEGTSAKEAICWQK-NMDALPTGCPQPALLDISWFTESMAAGQPVPEE ENSRNOP00000018320/1-495 LDVYSSEVTHVVMEETSAKEAICWQK-DMNALLPDCPQPALLDISWFTESMAAGQPVPEE ENSCPOP00000013323/1-489 LDVYSSEVTHVVMEQTSAEEAVCWQE-QEATLHPGCPCPALLDITWFTESMAAGQPVPVE XP_004839985.1/1-493 LDTYSSEVTHVVMEGTSAGEAACWQE-NEAAPPPGCPRPALLDISWFTESMAAGQPVPVE **. **:.****** *** ** .**: : ..*. ******:*:***:.****** * ENSP00000379174/1-508 CRHRLEVAGPRKGPLSPAWMPAYACQRPTPLTHHNTGLSEALEILAEAAGFEGSEGRLLT ENSMUSP00000105463/1-511 GRHHLEVAEPRKEPPVSASMPAYACQRPSPLTHHNTLLSEALETLAEAAGFEANEGRLLS ENSRNOP00000018320/1-495 VRHRLEVAEPRKEPPISVTIPAYACQRPSPLTPHNTLLSEALETLAEAAGFEGKEGRFLT ENSCPOP00000013323/1-489 GRHRLEVPEPRKRPPNPV-MPAYACQRSTPLMHHNSSLSEALETLAEAAGFEGSEGRLLS XP_004839985.1/1-493 GRHRLEEAELRKGPPNPAAMPAYACQRSTPLMHHNSSLSEALETLAEAAGFEGSEGRLLS **:** . ** * .. :*******.:** **: ****** ********..***:*: ENSP00000379174/1-508 FCRAASVLKALPSPVTTLSQLQGLPHFGEHSSRVVQELLEHGVCEEVERVRRSER----- ENSMUSP00000105463/1-511 FSRAASVLKSLPCPVASLSQLHGLPYFGEHSTRVIQELLEHGTCEEVKQVRCSERYQTMK ENSRNOP00000018320/1-495 FYRAASMLKSLPYPVTSLSQLHGLPYFGEHSFRVIQELLEHGTCEEVEQIRCSERHQTMK ENSCPOP00000013323/1-489 FRRAASVLKALPWPVTELSQLQGLPHFGEHSTSVIQELLERGVCEEVERVRCSERYRTMK XP_004839985.1/1-493 FCRAASVLRALPWPVTVLSQLQGLPNFGEHSSRIVQELLERGVCEEVKRVRSSERYRTMK * ****:*::** **: ****:*** ***** ::*****:*.****:::* *** ENSP00000379174/1-508 -----------------------------------APAPPGPEHPS----PAVRCRCPA- ENSMUSP00000105463/1-511 LFTQVFGVGVKTANRWYQEGLRTLDELREQPQRLTQQQKAGLQYYQDLSTPVRRADAEAL ENSRNOP00000018320/1-495 LFTHIFGVGVKTASRWYQEGLRTLDELREQPQRLTQQQKAGLQYYQDLSTPVSRAEAEAL ENSCPOP00000013323/1-489 LFTQIFGVGVKTANQWYQEGLRTLDELQEQPRRLTRQQQAGLQHHLDLCTP-GRPDAEAL XP_004839985.1/1-493 LFTQVFGVGVKTANRWYQEGLRTLDELREQPQRLTRQQRAGLQHHRDLCTPVGRPDAEAL .* :: * * . * ENSP00000379174/1-508 -------------------AGG---GGSCGAGPAWGHRHADRR-----LP--------QG ENSMUSP00000105463/1-511 QQLIEAAVRQTLPGATVTLTGGFRRGKLQGHDVDFLITHPEEGQEVGLLPKVMSCLQSQG ENSRNOP00000018320/1-495 QQLVEAAMREILPGATVTLTGGFRRGKLQGHDVDFLITHPEEGQEVGLLPRVMRCLQSQG ENSCPOP00000013323/1-489 QQLVEATVRQALPGATVTLTGGFRRGKPQGHDVDFLITHPEEGREAGLLPSVLRQLQSQD XP_004839985.1/1-493 QRLVEATVGQALPGATVMLTGGFRRGKLQGHDVDFLITHPEEGREVGLLPSVVCQLQSQG :** * * . : *.:. ** *. ENSP00000379174/1-508 LILYHQHQHSCCESPTRLAQQ--SHMDAFERSFCIFRLPQPPGAAVGGSTRPCPSWKAVR ENSMUSP00000105463/1-511 LVLYHQYHRSHLADSAHNLRQRSSTMDAFERSFCILGLPQPQQAALAGALPPCPTWKAVR ENSRNOP00000018320/1-495 LVLYHQYHRSHLADSAHILRQR-STMDAFERSFCILRLPQSQQAALEGPLHPCPTWKAVR ENSCPOP00000013323/1-489 LVLYHQHQRSRLGDPSRLAQQS-HTMDAFERSLCILRLPLPSK---GADPESQPAWKAVR XP_004839985.1/1-493 LVLYHQHQRSHLGDPDHLARQS-HTMDAFERSLCILRLLQPSQPAKGADSEPRP-WRAVR *:****:::* .. : :* *******:**: * . . . * *:*** ENSP00000379174/1-508 VDLVVAPVSQFPFALLGWTGSKLFQRELRRFSRKEKGLWLNSHGLFDPEQGSSSGKTPRS ENSMUSP00000105463/1-511 VDLVVTPSSQFPFALLGWTGSQSLSGSYGGSAVKRRGCGLTAMGCLILS----------- ENSRNOP00000018320/1-495 VDLVVTPNSQFPFALLGWTGSQFFERELRRFSRQEKGLCLNSHGLFDPE----------- ENSCPOP00000013323/1-489 VDLVVTPWSQFPFALLGWTGSQLFERELRRFSRKEKGLCLNSHGLFDPE----------- XP_004839985.1/1-493 VDLVVAPWSQFPFALLGWTGSKLFERDLRRFSRKEKGLCLNSHGLFDPE----------- *****:* *************: :. . : :.:* *.: * : . ENSP00000379174/1-508 RKSCFCCRRHFSKRLQRKTSSDTWALSTFLQSRETPEPACVPHFHSGNWAAPNLATECLQ ENSMUSP00000105463/1-511 -------RREFSMQLLRKMFSDSWASSTFLQSREM------------------------- ENSRNOP00000018320/1-495 -------RKTF--------FHATSEEDVFRF---------------------------LG ENSCPOP00000013323/1-489 -------QRTC--------FHVASEEDIFRH---------------------------LG XP_004839985.1/1-493 -------QKSC--------FHVASEEDIFRH---------------------------LG :: : . * ENSP00000379174/1-508 ADMLPPDPHLHPSPPRPGSSGGQLCLQDQLSPCWCAAGCDEVGALSASLITV ENSMUSP00000105463/1-511 -----PELRNACGLPHPSIQK------------------------------- ENSRNOP00000018320/1-495 LKYLPPEQRNA----------------------------------------- ENSCPOP00000013323/1-489 LTYLPPEQRNA----------------------------------------- XP_004839985.1/1-493 LAYLPPEQRNA----------------------------------------- *: :