CLUSTAL W(1.81) multiple sequence alignment ENSMUSP00000020931/1-1097 MAKRKEENFCSPENAKRPRQEELEDFDKDGDEDECTISFTNGTSTLTAAEVGIIESIQLR ENSRNOP00000007073/1-1097 MAKRKEENFCSPENAKRPRQEELEDFDKDGDEDECTISFTNGTSTLTAAEVGIIESIQLR ENSP00000370672/1-1117 MAKRKEENFSSPKNAKRPRQEELEDFDKDGDEDECK------GTTLTAAEVGIIESIHLK ENSCPOP00000013291/1-1096 MAKRKEDGFFSPENAKRPRRES-EDFDKDSDEDECAVSLTKDSSTLTAADVGIIESIHLK XP_004839493.1/1-1067 MAKRKEDSLPSPETAKRPRREP-EDFGRDSDEDECSVSLTKGGSTLTVAEVGIIESIQLR ******:.: **:.*****:* ***.:*.***** :***.*:*******:*: ENSMUSP00000020931/1-1097 NFMCHSMLGPFKFGSNVNFVVGNNGS--------------------------GKSAVLTA ENSRNOP00000007073/1-1097 NFMCHSMLGPFKFGSNVNFVVGNNGS--------------------------GKSAVLTA ENSP00000370672/1-1117 NFMCHSMLGPFKFGSNVNFVVGNNGSWSAVVRSRLNATSASQVQAILLFQPCGKSAVLTA ENSCPOP00000013291/1-1096 NFMCHSMLGPFKFGSNVNFVVGNNGS--------------------------GKSAVLTA XP_004839493.1/1-1067 NFMCHSMLGPFKFGSNVNFVVGNNGS--------------------------GKSAVLTA ************************** ******** ENSMUSP00000020931/1-1097 LIVGLGGKAVATNRGSSLKGFVKAGQNSADISITLRNRGDDAFRANVYGDSIVVQQHISV ENSRNOP00000007073/1-1097 LIVGLGGKAVATNRGSSLKGFVKAGQNSADISITLRNRGDDAFRANVYGDSIVVQQHISV ENSP00000370672/1-1117 LIVGLGGRAVATNRGSSLKGFVKDGQNSADISITLRNRGDDAFKASVYGNSILIQQHISI ENSCPOP00000013291/1-1096 LIVGLGGKAVATNRGSSLKGFVKDGQNSADITVTLRNRGEDAYRANVYGDSIVVQQHITL XP_004839493.1/1-1067 LIVGLGGKAVATNRGSSLKGFVKDGQSSADITVTLRNRGDDAYRANVYGDSIVVQQHISM *******:*************** **.****::******:**::*.***:**::****:: ENSMUSP00000020931/1-1097 DGSRSYKLKSEKGTVVSTRKEELIAILDHFNIQVDNPVSVLTQEMSKQFLQSKNEGDKYK ENSRNOP00000007073/1-1097 DGSRSYKLKSEKGTVVSTRKEELIAILDHFNIQVDNPVSVLTQEMSKQFLQSKNEGDKYK ENSP00000370672/1-1117 DGSRSYKLKSATGSVVSTRKEELIAILDHFNIQVDNPVSVLTQEMSKQFLQSKNEGDKYK ENSCPOP00000013291/1-1096 DGSRSYKLKSQTGTVVSTRKEELVAILDHFNIQVDNPVSVLTQEMSKQFLQSKNEGDKYK XP_004839493.1/1-1067 DGSRSYKLKSQTGAVVSTRKEELIAVLDHFNIQVDNPVSVLTQEMSKQFLQSKNEGDKYK ********** .*:*********:*:********************************** ENSMUSP00000020931/1-1097 FFMKATQLEQMKEDYSYIMETKERTKEQINQGEERLTELKRQCLEKEERFQNIAGLSTMK ENSRNOP00000007073/1-1097 FFMKATQLEQMKEDYSYIMETKERTKEQINQGEERLTELKRQCLEKEERFQNIAGLSTMK ENSP00000370672/1-1117 FFMKATQLEQMKEDYSYIMETKERTKEQIHQGEERLTELKRQCVEKEERFQSIAGLSTMK ENSCPOP00000013291/1-1096 FFMKATQLEQMKEDYSYIMETKERTKEQINQGEERLTELKRQCLEKEERFQSIAGLSTMK XP_004839493.1/1-1067 VSVT-----------------------------RRLTELKRQCLEKEERFQSIAGLSTMK . :. .*********:*******.******** ENSMUSP00000020931/1-1097 TNLEYLKHEMAWAVVNEIEKQLNAIRDNIKIGEERAAKLDRKMEEQQVRLNDAEKKYKDI ENSRNOP00000007073/1-1097 TNLEYLKHEMAWAVVNEIEKQLNAIRDNIKIGEERAAKLDRKMEEQQVRLNDAEKKYKDI ENSP00000370672/1-1117 TNLESLKHEMAWAVVNEIEKQLNAIRDNIKIGEDRAARLDRKMEEQQVRLNEAEQKYKDI ENSCPOP00000013291/1-1096 TNLEYLKHEMAWAVVNEIEKQLNAIRDNIKIGEDRAARLERKMEEQQVKLNEAEKKYADI XP_004839493.1/1-1067 TNLEYLKHEMAWAVVNEIEKQLNAIRDNIKIGEDRAARLDRKMEEQQVKLNEAEKKYKDI **** ****************************:***:*:********:**:**:** ** ENSMUSP00000020931/1-1097 QDKLEKISEETNARAPECMALKTDVIARTRAFNDAEVLYNRSLNEYKALKKDGEQLCKRI ENSRNOP00000007073/1-1097 QDKLEKISEETNARAPECMALKTDVIARTRAFNDAEVLYNRSLNEYKALKKDGEQLCKRI ENSP00000370672/1-1117 QDKLEKISEETNARAPECMALKADVVAKKRAYNEAEVLYNRSLNEYKALKKDDEQLCKRI ENSCPOP00000013291/1-1096 QDKLEKISQETNARAPECMALKADVIAKKRDYNEAEVLYNHSLNEYKALKKDDEQLCKRI XP_004839493.1/1-1067 QDKLEKISQETNARAPECMALKADVTAKKRDYNEAEVLYNRSLNEYKALKKDDEQLCKRI ********:*************:** *:.* :*:******:***********.******* ENSMUSP00000020931/1-1097 EELKKSTDQSLEPERLERQKRICWLKEKVKALQDQEHTVNQEAEQFEQAIEKDKQEHGRV ENSRNOP00000007073/1-1097 EELKKSTDQSLEPERLERQKRICWLKEKVKALQDQENTVNQEVEQFEQAIEKDKQEHVRI ENSP00000370672/1-1117 EELKKSTDQSLEPERLERQKKISWLKERVKAFQNQENSVNQEIEQFQQAIEKDKEEHGKI ENSCPOP00000013291/1-1096 EELKKSADQFLETERLERQKKIWWLKERLKAFQDQENSINQEMEQFQQAIEKGRAEHDRI XP_004839493.1/1-1067 EELKKSADQFLETERLERQKKICWLKERLKAFQDQENSVSQEMEQFQQATEKGREEYARI ******:** **.*******:* ****::**:*:**:::.** ***:** **.: *: :: ENSMUSP00000020931/1-1097 RKEDIEVRHALNYNQRQLKELKDSKTDRLKRFGPHVPALLEAIDDAYRRRQFTHKPIGPL ENSRNOP00000007073/1-1097 KREDVEVRHTLSYNQRQLKELKDSKTDRLKRFGPHVPALLEAIDDAYRRRQFTHKPIGPL ENSP00000370672/1-1117 KREELDVKHALSYNQRQLKELKDSKTDRLKRFGPNVPALLEAIDDAYRQGHFTYKPVGPL ENSCPOP00000013291/1-1096 RREELDVKHALNYSQRQLKELKDSKTDRLKRFGPHVPALLEAIDDAYRRGYFTHKPVGPL XP_004839493.1/1-1067 RREELDVKHALNYNQRQLKELKDSKTDRLKRFGPHVPALLEAIDDAYRRGYFTHKPVGPL ::*:::*:*:*.*.********************:*************: **:**:*** ENSMUSP00000020931/1-1097 GACIHLRDPELALAIESCLKGLLQAYCCHNHADERVLQSLMKKFYPPGTSRPQIIVSEFR ENSRNOP00000007073/1-1097 GACIHLRDPELALAIESCLKGLLQAYCCHNHADERVLQSLMKKFYPPGTSRPQIIVSEFR ENSP00000370672/1-1117 GACIHLRDPELALAIESCLKGLLQAYCCHNHADERVLQALMKRFYLPGTSRPPIIVSEFR ENSCPOP00000013291/1-1096 GACIHLRDPELALAIESCLKGLLQAYCCHNHADERVLQALMKRFYSPGTSRPQIIVSEFQ XP_004839493.1/1-1067 GACIHLRDPELALAVESCLKGLLQAYCCHNHADERVLQALMKRFYSPGTSRPQIIVSEFQ **************:***********************:***:** ****** ******: ENSMUSP00000020931/1-1097 DEVYDVRLRAAYHPEFPTVLTALEIDNAVVANSLIDMRSIETVLLIKNNSVARAVMQSQK ENSRNOP00000007073/1-1097 NEVYDVRLRAAYHPEFPTVLTALEIDNAVVANSLIDMRSIETVLLIKNNSVARAVMQSQK ENSP00000370672/1-1117 NEIYDVRHRAAYHPDFPTVLTALEIDNAVVANSLIDMRGIETVLLIKNNSVARAVMQSQK ENSCPOP00000013291/1-1096 NEMYDVRHRTVHHPEFPTVLTALEIDNAVVANSLIDMRNIETVLLIKNNSVARAVMQSQK XP_004839493.1/1-1067 NEIYDVRHRAVHHPEFPTVLTALEIDNAVVANSLIDMRNIETVLLIKSNAVARAVMQSQQ :*:**** *:.:**:***********************.********.*:*********: ENSMUSP00000020931/1-1097 PPKNCREAFTADGDQVFAGRYYSSESTRPKFLSRDVDSEISDLETEIENKKGHIITLQQR ENSRNOP00000007073/1-1097 PPKNCREAFTADGDQVFAGRYYSSESTRPKFLSRDVDSEISDLETEIENKKGHIMNLQHR ENSP00000370672/1-1117 PPKNCREAFTADGDQVFAGRYYSSENTRPKFLSRDVDSEISDLENEVENKTAQILNLQQH ENSCPOP00000013291/1-1096 PPKNCREAFTADGDQVFAGRYYSSENTRPKFLSRDVDSEISNLENEVENKKAQIVNLQQH XP_004839493.1/1-1067 PPKNCREAFTADGDQVFAGRYYSSENTRPKFLSRDVDSEISNLENEVENKRAQLVNLQQH *************************.***************:**.*:*** .:::.**:: ENSMUSP00000020931/1-1097 LSALEKDIKRNEELLKRCQLHYKEIKMKIRKNISEIRELENIEEHQSVDIATLEDEAEEN ENSRNOP00000007073/1-1097 LSALEKDIKRNEELLKRCQLHYKEIKMKIRKNISEIRELENIEEHQSVDIATLEDEAEEN ENSP00000370672/1-1117 LSALEKDIKHNEELLKRCQLHYKELKMKIRKNISEIRELENIEEHQSVDIATLEDEAQEN ENSCPOP00000013291/1-1096 LSAREKDIKQNEELLKRCQLHYKELKMKIRKSSSEIRELENIEEHKSVDIATLEDEAHDN XP_004839493.1/1-1067 LSAREKDVKQNEELLKRCQLHYKELKMKIRKNISEIRELENIEEHKSVDIATLEDEAHDN *** ***:*:**************:******. ************:***********.:* ENSMUSP00000020931/1-1097 KIKMQMVEKNMEQQKENMENLKSLKIEAENKYDTIKLKINQLSELADPLKDELNLADSEV ENSRNOP00000007073/1-1097 KIKMQMVEKNMEQQKENMENLKTLKIEAENKYDTIKLKINQLSELADPLKDELNLADSEV ENSP00000370672/1-1117 KSKMKMVEEHMEQQKENMEHLKSLKIEAENKYDAIKFKINQLSELADPLKDELNLADSEV ENSCPOP00000013291/1-1096 KMKMKMTEKQMEQQKKNLEHFKSLKIEAENKYDTIKLKINQLSELADPLKDELNLADSEV XP_004839493.1/1-1067 KIKMKMTEKQMEQQKESLEHFKSLKKEAENKYDTVKLKINQLSELADPLKDELNLADSEV * **:*.*::*****:.:*::*:** *******::*:*********************** ENSMUSP00000020931/1-1097 DSQKRGKQHYEDKQKEHLDTLNKKRRELDMKEKELQEKMSQARQICPERIEVKKSASILD ENSRNOP00000007073/1-1097 DSQKRGKQHYEDKQKEHMDTLNKKRRELDMKEKELQEKMSQARQICPERIEVKKSASILD ENSP00000370672/1-1117 DNQKRGKRHYEEKQKEHLDTLNKKKRELDMKEKELEEKMSQARQICPERIEVEKSASILD ENSCPOP00000013291/1-1096 DNQKRGKRHYEDKQKEHLDTLNKKKRELDMKERELEEKMSQARQICPERIEVKKSASMLD XP_004839493.1/1-1067 DNQKRGKRHYEDKQKEHLDTLNKKKRELDMKEKELEEKMSQARQICPERIEVKKSASMLD *.*****:***:*****:******:*******:**:****************:****:** ENSMUSP00000020931/1-1097 KEINRLRQKIQAEHASHGDREEIMKQYQEARETYLDLDNKVRTLRRFIKLLEEIMTHRYK ENSRNOP00000007073/1-1097 KEINRLRQKIQAEHASHGDREEIMKQYQEARETYLDLDSKVRTLRRFIKLLEEIMTHRYK ENSP00000370672/1-1117 KEINRLRQKIQAEHASHGDREEIMRQYQEARETYLDLDSKVRTLKKFIKLLGEIMEHRFK ENSCPOP00000013291/1-1096 KEINRLRQKIQAEHASHGDREEIMRQYQEARETYLDLDSKVRTLKKFIKLLEEIMTHRYK XP_004839493.1/1-1067 KEINRLRQKIQAEHASHGDREEIMRQYQEARETYLDLDNKVRTLKRFIKLLEEIMTHRYK ************************:*************.*****::***** *** **:* ENSMUSP00000020931/1-1097 TYQQFRRCLTLRCKLYFDNLLSQRAYCGKMNFDHKNETLSITVQPGEGNKASFNDMRALS ENSRNOP00000007073/1-1097 TYQQFRRCLTLRCKLYFDNLLSQRAYCGKMNFDHKNETLSISVQPGEGNKASFNDMRALS ENSP00000370672/1-1117 TYQQFRRCLTLRCKLYFDNLLSQRAYCGKMNFDHKNETLSISVQPGEGNKAAFNDMRALS ENSCPOP00000013291/1-1096 TYQQFRRCLTLRCKLYFDNLLSQRAYCGKMNFDHKNETLAISVQPGEGNKAAFNDMRALS XP_004839493.1/1-1067 TYQQFRRCLTLRCKLYFDNLLSQRAYCGKMNFDHKNETLAISVQPGEGNKAAFNDMRALS ***************************************:*:*********:******** ENSMUSP00000020931/1-1097 GGERSFSTVCFILSLWSIAESPFRCLDEFDVYMDMVNRRIAMDMILKMADSQRFRQFILL ENSRNOP00000007073/1-1097 GGERSFSTVCFILSLWSIAESPFRCLDEFDVYMDMVNRRIAMDMILKMADSQRFRQFILL ENSP00000370672/1-1117 GGERSFSTVCFILSLWSIAESPFRCLDEFDVYMDMVNRRIAMDLILKMADSQRFRQFILL ENSCPOP00000013291/1-1096 GGERSFSTVCFILSLWSIAESPFRCLDEFDVYMDMVNRRIAMDMILKMADSQRFRQFILL XP_004839493.1/1-1067 GGERSFSTVCFILSLWSIAESPFRCLDEFDVYMDMVNRRIAMDMILKMADSQRFRQFILL *******************************************:**************** ENSMUSP00000020931/1-1097 TPQSMSSLPSSKLIRILRMSDPERGQTTLPFRPVTQEEDDSAS ENSRNOP00000007073/1-1097 TPQSMSSLPSSKLIRILRMSDPERGQTTLPFRPVTQEEDDSAS ENSP00000370672/1-1117 TPQSMSSLPSSKLIRILRMSDPERGQTTLPFRPVTQEEDDDQR ENSCPOP00000013291/1-1096 TPQSMSSLPSSKLIRILRMSDPERGQTTLPFRPVTQEDDDDGN XP_004839493.1/1-1067 TPQSMSSLPSSKLIRILRMSDPERGQTTLPFRPVTWEDEDERS *********************************** *::*.