CLUSTAL W(1.81) multiple sequence alignment ENSMUSP00000131355/1-1175 MAVCGRVRGMFRLSAALPL-LLLAAAGAQNGHG-------QGQGPGTNFGPFPGQGGGGS ENSRNOP00000025570/1-1171 MAVCGRVRRMFRLSAALQL-LLLVAAGVQNSHG-------QGQGPGVNFGPFAGQAGGGN ENSP00000205061/1-1203 MAACGRVRRMFRLSAALHL-LLLFAAGAEKLPGQGVHS--QGQGPGANFVSFVGQAGGGG ENSCPOP00000012955/1-1166 ---------------------LLAAVGAQKILAPGSHSQNQGQGPGANFVPFVGQAGGGG XP_004842913.1/1-1178 MAACGRVLRLFRSSAVLQLVLLLAAVGAQKFLGQGSHS--QGQGAGANFVPFVGQAGGGG ** *.*.:: . ****.*.** .* **.***. ENSMUSP00000131355/1-1175 PAGQQPPQQPQLS--------QQQQQPPPQQQQQQQQQSLFAAGGLPARRGGAGPGGTGG ENSRNOP00000025570/1-1171 PVGQQPPQLPQLSQQ------QQQQQPPPQQQQP------FPAGGLPARRGGAGPGGTGG ENSP00000205061/1-1203 PAGQQLPQLPQSSQL------QQQQQQQQQQQQPQPPQPPFPAGGPPARRGGA---GAGG ENSCPOP00000012955/1-1166 PVGQSLSQSLQFQQQQQ----QQQQQQQQQQQAAQPPQPLFPAGGPPARRSGAGPGGAGG XP_004842913.1/1-1178 PVGQQQPQVPQSLQFQQQQQQQQQQQQQQQQQPPQPPQPPFPAGGPSARRGGAGPGGAGG *.**. .* * ***** *** *.*** .***.** *:** ENSMUSP00000131355/1-1175 GWKLAEEESCREDVTRVCPKHTWSNNLAVLECLQDVREPENEISSDCNHLLWNYKLNLTT ENSRNOP00000025570/1-1171 GWKLAEEESCREDVTRVCPKHTWSNNLAVLECLQDVREPENEISSDCNHLLWNYKLNLTT ENSP00000205061/1-1203 GWKLAEEESCREDVTRVCPKHTWSNNLAVLECLQDVREPENEISSDCNHLLWNYKLNLTT ENSCPOP00000012955/1-1166 GWKLAEEESCREDVTRVCPKHTWSNNLAVLECLQDVREPENEISSDCNHLLWNYKLNLTT XP_004842913.1/1-1178 SWKLAEEESCREDVTRVCPKHTWSNNLAVLECLQDVRE-----------LLWNYKLNLTT .************************************* *********** ENSMUSP00000131355/1-1175 DPKFESVAREVCKSTISEIKECAEEPVGKGYMVSCLVDHRGNITEYQCHQYITKMTAIIF ENSRNOP00000025570/1-1171 DPKFESVAREVCKSTISEIKECAEEPVGKGYMVSCLVDHRGNITEYQCHQYITKMTAIIF ENSP00000205061/1-1203 DPKFESVAREVCKSTITEIKECADEPVGKGYMVSCLVDHRGNITEYQCHQYITKMTAIIF ENSCPOP00000012955/1-1166 DPKFESVAREVCKSTISEIKECADEPVGKGYMVSCLVDHRGNITEYQCHQYITKMTAIIF XP_004842913.1/1-1178 DPKFESVAREVCKSTISEIKECADEPVGKGYMVSCLVDHRGNITEYQCHQYITKMTAIIF ****************:******:************************************ ENSMUSP00000131355/1-1175 SDYRLICGFMDDCKNDINLLKCGSIRLGEKDAHSQGEVVSCLEKGLVKEAEEKEPKIQVS ENSRNOP00000025570/1-1171 SDYRLICGFMDDCKNDINLLKCGSIRLGEKDAHSQGEVVSCLEKGLVKEAEEKEPKIQVS ENSP00000205061/1-1203 SDYRLICGFMDDCKNDINILKCGSIRLGEKDAHSQGEVVSCLEKGLVKEAEEREPKIQVS ENSCPOP00000012955/1-1166 SDYRLICGFMDDCKNDINILKCGSIRLGEKDAHSQGEVVSCLEKGLVKEAEEKEPKVQVS XP_004842913.1/1-1178 SDYRLICGFMDDCKNDINILKCGSIRLGEKDAHSQGEVVSCLEKGLVKEAEEKEPKIQVS ******************:*********************************:***:*** ENSMUSP00000131355/1-1175 ELCKKAILRVAELSSDDFHLDRHLYFACRDDRERFCENTQAGEGRVYKCLFNHKFEESMS ENSRNOP00000025570/1-1171 ELCKKAILRVAELSSDDFHLDRHLYFACRDDRERFCENTQAGEGRVYKCLFNHKFEESMS ENSP00000205061/1-1203 ELCKKAILRVAELSSDDFHLDRHLYFACRDDRERFCENTQAGEGRVYKCLFNHKFEESMS ENSCPOP00000012955/1-1166 EQCKKAILRVAELSSDDFHLDRHLYFACRDDRERFCENTQAGEGRVYKCLFNHKFEESMS XP_004842913.1/1-1178 ELCKKAILRVAELSSDDFHLDRHLYFACRDDRERFCENTQAGEGRVYKCLFNHKFEESMS * ********************************************************** ENSMUSP00000131355/1-1175 EKCREALTTRQKLIAQDYKVSYSLAKSCKSDLKKYRCNVENLPRSREARLSYLLMCLESA ENSRNOP00000025570/1-1171 EKCREALTTRQKLIAQDYKVSYSLAKSCKSDLKKYRCNVENLPRSREARLSYLLMCLESA ENSP00000205061/1-1203 EKCREALTTRQKLIAQDYKVSYSLAKSCKSDLKKYRCNVENLPRSREARLSYLLMCLESA ENSCPOP00000012955/1-1166 EKCREALTTRQKLIAQDYKVSYSLAKSCKSDLKKYRCNVENLPRSREARLSYLLMCLESA XP_004842913.1/1-1178 EKCREALTTRQKLIAQDYKVSYSLAKSCKSDLKKYRCNVENLPRSREARLSYLLMCLESA ************************************************************ ENSMUSP00000131355/1-1175 VHRGRQVSSECQGEMLDYRRMLMEDFSLSPEIILSCRGEIEHHCSGLHRKGRTLHCLMKV ENSRNOP00000025570/1-1171 VHRGRQVSSECQGEMLDYRRMLMEDFSLSPEIILSCRGEIEHHCSGLHRKGRTLHCLMKV ENSP00000205061/1-1203 VHRGRQVSSECQGEMLDYRRMLMEDFSLSPEIILSCRGEIEHHCSGLHRKGRTLHCLMKV ENSCPOP00000012955/1-1166 VHRGRQVSSECQGEMLDYRRMLMEDFSLSPEIILSCRGEIERHCSGLHRKGRTLHCLMKV XP_004842913.1/1-1178 VHRGRQVSSECQGEMLDYRRMLMEDFSLSPEIILSCRGEIEHHCSGLHRKGRTLHCLMKV *****************************************:****************** ENSMUSP00000131355/1-1175 VRGEKGNLGMNCQQALQTLIQETDPGADYRIDRALNEACESVIQTACKHIRSGDPMILSC ENSRNOP00000025570/1-1171 VRGEKGSLGMNCQQALQTLIQETDPGADYRIDRALNEACESVIQTACKHIRSGDPMILSC ENSP00000205061/1-1203 VRGEKGNLGMNCQQALQTLIQETDPGADYRIDRALNEACESVIQTACKHIRSGDPMILSC ENSCPOP00000012955/1-1166 VRGEKGNLGMNCQQALQTLIQETDPGADYRIDRALNEACESVIQTACKHIRSGDPMILSC XP_004842913.1/1-1178 VRGEKGNLGMNCQQALQTLIQETDPGADYRIDRALNEACESVIQTACKHIRSGDPMILSC ******.***************************************************** ENSMUSP00000131355/1-1175 LMEHLYTEKMVEDCEHRLLELQYFISRDWKLDPVLYRKCQGDASRLCHTHGWNETSELMP ENSRNOP00000025570/1-1171 LMEHLYTEKMVEDCEHRLLELQYFISRDWKLDPVLYRKCQGDASRLCHTHGWNETSELMP ENSP00000205061/1-1203 LMEHLYTEKMVEDCEHRLLELQYFISRDWKLDPVLYRKCQGDASRLCHTHGWNETSEFMP ENSCPOP00000012955/1-1166 LMEHLYTEKMVEDCEHRLLELQYFISRDWKLDPVLYRKCQGDASRLCHTHGWNETSELMP XP_004842913.1/1-1178 LMEHLYTEKMVEDCEHRLLELQYFISRDWKLDPVLYRKCQGDASRLCHTHGWNETSELMP *********************************************************:** ENSMUSP00000131355/1-1175 PGAVFSCLYRHAYRTEEQGRRLSRECRAEVQRILHQRAMDVKLDPALQDKCLIDLGKWCS ENSRNOP00000025570/1-1171 PGAVFSCLYRHAYRTEEQGRRLSRECRAEVQRILHQRAMDVKLDPALQDKCLIDLGKWCS ENSP00000205061/1-1203 QGAVFSCLYRHAYRTEEQGRRLSRECRAEVQRILHQRAMDVKLDPALQDKCLIDLGKWCS ENSCPOP00000012955/1-1166 PGAVFSCLYRHAYRTEEQGRRLSRECRAEVQRILHQRAMDVKLDPALQDKCLIDLGKWCS XP_004842913.1/1-1178 PGAVFSCLYRHAYRTEEQGRRLSRECRAEVQRILHQRAMDVKLDPALQDKCLIDLGKWCS *********************************************************** ENSMUSP00000131355/1-1175 EKTETGQELECLQDHLDDLAVECRDIVGNLTELESEDIQIEALLMRACEPIIQNFCHDVA ENSRNOP00000025570/1-1171 EKTETGQELECLQDHLDDLAVECRDIVGNLTELESEDIQIEALLMRACEPIIHNFCHDVA ENSP00000205061/1-1203 EKTETGQELECLQDHLDDLVVECRDIVGNLTELESEDIQIEALLMRACEPIIQNFCHDVA ENSCPOP00000012955/1-1166 EKTETGQELECLQDHLDDLAVECRDIVGNLTELESEDIQIEALLMRACEPIIQNFCHDVA XP_004842913.1/1-1178 EKTETGQELECLQDHLDDLAVECRDIVGNLTELESEDIQIEALLMRACEPIIQNFCHDVA *******************.********************************:******* ENSMUSP00000131355/1-1175 DNQIDSGDLMECLIQNKHQKDMNEKCAIGVTHFQLVQMKDFRFSYKFKMACKEDVLKLCP ENSRNOP00000025570/1-1171 DNQIDSGDLMECLIQNKHQKDMNEKCAIGVTHFQLVQMKDFRFSYKFKMACKEDVLKLCP ENSP00000205061/1-1203 DNQIDSGDLMECLIQNKHQKDMNEKCAIGVTHFQLVQMKDFRFSYKFKMACKEDVLKLCP ENSCPOP00000012955/1-1166 DNQIDSGDLMECLIQNKHQKDMNEKCAIGVTHFQLVQMKDFRFSYKFKMACKEDVLKLCP XP_004842913.1/1-1178 DNQIDSGDLMECLIQNKHQKDMNEKCAIGVTHFQLVQMKDFRFSYKFKMACKEDVLKLCP ************************************************************ ENSMUSP00000131355/1-1175 NIKKKVDVVICLSTTVRNDTLQEAKEHRVSLKCRKQLRVEELEMTEDIRLEPDLYEACKS ENSRNOP00000025570/1-1171 NIKKKVDVVICLSTTVRNDTLQEAKEHRVSLKCRKQLRVEELEMTEDIRLEPDLYEACKS ENSP00000205061/1-1203 NIKKKVDVVICLSTTVRNDTLQEAKEHRVSLKCRRQLRVEELEMTEDIRLEPDLYEACKS ENSCPOP00000012955/1-1166 NIKKKVDVVICLSTTVRNDTLQEAKEHRVSLKCRKQLRVEELEMTEDIRLEPDLYEACKS XP_004842913.1/1-1178 NIKKKVDVVICLSTTVRNDTLQEAKEHRVSLKCRKQLRVEELEMTEDIRLEPDLYEACKS **********************************:************************* ENSMUSP00000131355/1-1175 DIKNYCSTVQYGNAQIIECLKENKKQLSTRCHQKVFKLQETEMMDPELDYTLMRVCKQMI ENSRNOP00000025570/1-1171 DIKNYCSTVQYGNAQIIECLKENKKQLSTRCHQRVFKLQETEMMDPELDYTLMRVCKQMI ENSP00000205061/1-1203 DIKNFCSAVQYGNAQIIECLKENKKQLSTRCHQKVFKLQETEMMDPELDYTLMRVCKQMI ENSCPOP00000012955/1-1166 DIKNHCSTVQYGNAQIIECLKENKKQLSNRCHQKVFKLQETEMMDPELDYTLMRVCKQMI XP_004842913.1/1-1178 DIRNHCSTVQYGNAQIIECLKENKKQLSTRCHQKVFKLQETEMMDPELDYTLMRVCKQMI **:*.**:********************.****:************************** ENSMUSP00000131355/1-1175 KRFCPEADSKTMLQCLKQNKNSELMDPKCKQMITKRQITQNTDYRLNPVLRKACKADIPK ENSRNOP00000025570/1-1171 KRFCPEADSKTMLQCLKQNKNSELMDPKCKQMITKRQITQNTDYRLNPVLRKACKADIPK ENSP00000205061/1-1203 KRFCPEADSKTMLQCLKQNKNSELMDPKCKQMITKRQITQNTDYRLNPMLRKACKADIPK ENSCPOP00000012955/1-1166 KRFCPEADSKTMLQCLKQNKNSELMDPKCKQMITKRQITQNTDYRLNPVLRKACKADIPK XP_004842913.1/1-1178 KRFCPEADSKTMLQCLKQNKNSELMDPKCKQMITKRQITQNTDYRLNPVLRKACKADIPK ************************************************:*********** ENSMUSP00000131355/1-1175 FCHGILTKAKDDSELEGQVISCLKLRYADQRLSSDCEDQIRIIIQESALDYRLDPQLQLH ENSRNOP00000025570/1-1171 FCHGILTKAKDDSELEGQVISCLKLRYADQRLSSDCEDQIRIIIQESALDYRLDPQLQLH ENSP00000205061/1-1203 FCHGILTKAKDDSELEGQVISCLKLRYADQRLSSDCEDQIRIIIQESALDYRLDPQLQLH ENSCPOP00000012955/1-1166 FCHGILTKAKDDSELEGQVISCLKLRYADQRLSSDCEDQIRIIIQESALDYRLDPQLQLH XP_004842913.1/1-1178 FCHGILTKAKDDSELEGQVISCLKLRYADQRLSSDCEDQIRIIIQESALDYRLDPQLQLH ************************************************************ ENSMUSP00000131355/1-1175 CSDEIANLCAEEAAAQEQTGQVEECLKVNLLKIKTELCKKEVLNMLKESKADIFVDPVLH ENSRNOP00000025570/1-1171 CSDEIANLCAEEAAAQEQTGQVEECLKVNLLKIRTELCKKEVLNMLKESKADIFVDPVLH ENSP00000205061/1-1203 CSDEISSLCAEEAAAQEQTGQVEECLKVNLLKIKTELCKKEVLNMLKESKADIFVDPVLH ENSCPOP00000012955/1-1166 CSDEIASLCAEEAAAQEQTGQVEECLKVNLLKIKTEMCKKEVLNMLKESKADIFVDPVLH XP_004842913.1/1-1178 CSDEIASLCAEEAAAQEQTGQVEECLKVNLLKIKTEMCKKEVLNMLKESKADIFVDPVLH *****:.**************************:**:*********************** ENSMUSP00000131355/1-1175 TACALDIKHHCAAITPGRGRQMSCLMEALEDKRVRLQPECKKRLNDRIEMWSYAAKVAPA ENSRNOP00000025570/1-1171 TACALDIKHHCAAITPGRGRQMSCLMEALEDKRVRLQPECKKRLNDRIEMWSYAAKVAPA ENSP00000205061/1-1203 TACALDIKHHCAAITPGRGRQMSCLMEALEDKRVRLQPECKKRLNDRIEMWSYAAKVAPA ENSCPOP00000012955/1-1166 TACALDIKHHCAAITPGRGRQMSCLMEALEDKRVRLQPECKKRLNDRIEMWSYAAKVAPA XP_004842913.1/1-1178 TACALDIKHHCAAITPGRGRQMSCLMEALEDKRVRLQPECKKRLNDRIEMWSYAAKVAPA ************************************************************ ENSMUSP00000131355/1-1175 DGFSDLAMQVMTSPSKNYILSVISGSICILFLIGLMCGRITKRVTRELKDR--------- ENSRNOP00000025570/1-1171 DGFSDLAMQVMTSPSKNYILSVISGSICILFLIGLMCGRITKRVTRELKDR--------- ENSP00000205061/1-1203 DGFSDLAMQVMTSPSKNYILSVISGSICILFLIGLMCGRITKRVTRELKDRLQYRSETMA ENSCPOP00000012955/1-1166 DGFSDLAMQVMTSPSKNYILSVISGSICILFLIGLMCGRITKRVTRELKDR--------- XP_004842913.1/1-1178 DGFSDLAMQVMTSPSKNYILSVISGSICILFLIGLMCGRITKRVTRELKDR--------- *************************************************** ENSMUSP00000131355/1-1175 --------------- ENSRNOP00000025570/1-1171 --------------- ENSP00000205061/1-1203 YKGLVWSQDVTGSPA ENSCPOP00000012955/1-1166 --------------- XP_004842913.1/1-1178 ---------------