CLUSTAL W(1.81) multiple sequence alignment ENSMUSP00000067516/1-907 MLLCTTSAHKLETVYDHKFLKMSIKESCAKEEKSQKKQTI-SSPTFNEDKKKGEISAGST ENSRNOP00000049813/1-910 MLLCTTSAHKLETVYDHKFPKMSIKESCGKEEKSQKKQTT-SSPTFDEDKKEGEISAGST ENSP00000356471/1-900 M---------------------SSKESCGKKETSQRKDTTTSSPNFGEKDKKERKTPASS ENSCPOP00000012840/1-908 LIVLTWSVGGLDKIKTHHLFKMSNKESYGKEEKSQRNGII-LSSIYNEDKNEKKASSGSA XP_004921223.1/1-852 MVV--WLVG-----------------------------------FFFTDL---------- : : . ENSMUSP00000067516/1-907 SSEHGVQPVSTKKRKLKADDTDNVYYNANRKNS-KRLNVEVFIPKKRLKFSSST------ ENSRNOP00000049813/1-910 SSEHCVKPVSTKKRKLKPDDTDIVYYNTNRKHSMKRLNVEVGLPKKRPKFSSST------ ENSP00000356471/1-900 TSSSSIRSVSSEKRKLKSDHTDVLYYNIKRRQGLKRLSVEIDTLRRRPKIGSSSQRPIKL ENSCPOP00000012840/1-908 SA-YCMKSVSSEKRKLKSDHTDIQYCNTKRRQELKRLNVEIDVSAKRPKISSSSLGPNKL XP_004921223.1/1-852 ---------------LKSDHTDIQYYNTKRRQERKRLNVEIDISGKKPKISSSSQGPIKL **.*.** * * :*:: ***.**: :: *:.**: ENSMUSP00000067516/1-907 QAVSYLNNNQMTSHSCSSNGTKD--TKV-----KDCKLTNIGSKLNYEIKNHSRIKITKD ENSRNOP00000049813/1-910 QVASYLNSNQITLHSSSSDGAKD--TKL-----KDCKLTNIGSKLDYEIKSRSLIKITKD ENSP00000356471/1-900 KEASYSNDNQIILQSPSSNGTKKDIHKCVDFKPKDIKLTNAGSKLDHGIKSLSSPKIASD ENSCPOP00000012840/1-908 QEASSSKNNQIISQS-TSNGTKK-LRKH-----KEIKFINVTSKLDHGIKYLTNPKISKD XP_004921223.1/1-852 QEASSSNNNQFISQS-TSNGTKK-YRKC-----KESKLINVTRKLDHGIKYLNNPKIAKD : .* :.**: :* :*:*:*. * *: *: * **:: ** . **:.* ENSMUSP00000067516/1-907 MKSKPVDQTKEKNWPSLLIQK-KMKELKKEKN--NKDSSEEL--EKCKKNHLPQNYNFSN ENSRNOP00000049813/1-910 MKSKAEDQTKEKNWPSLLIQK-KMKELKKEKN--NKDSSEEL--EKCTKNQPPQNYNFSN ENSP00000356471/1-900 VKPKAEGQASENKWSHLLVQREKMKELKKGRNSKFRDNSEKCVLEKWKRNQFSQDYNSNK ENSCPOP00000012840/1-908 MKSKVEEHTREKEWPHLLLQTEKMKEPKKERN-KFRDSSEKC---KHKKNQLSQDCNSNK XP_004921223.1/1-852 MKPKVEGQTREKKWPHLLVQRETMKELKRERH-KFRDSSEKS---KCKKNQFSQDY-SNK :*.* :: *::*. **:* .*** *: :: :*.**: * .:*: .*: .: ENSMUSP00000067516/1-907 MIKESFESGRKKISFKIPKKSSTTLQKLVEEKIFTIDSSKSKSKQEEKQHLQSHQMSLNL ENSRNOP00000049813/1-910 IIKEPLESGRKKISFKIPKKSSSALQKLAEENIFSVDSSKSKSKQEGKEHLQSHRVSLSL ENSP00000356471/1-900 IIKEPLGSRRQKISFKIPIKSRDTLQKLVEENVFNIDSNNSKTKQEEREYLESSQVSLNV ENSCPOP00000012840/1-908 INYEPFDSRTRKINFKIPVKSCNNLQKLVEENVFNLVSNKVKTKQEAREFPEDSHVSLNL XP_004921223.1/1-852 IIHEP-DSRKKKISFKIPIKSSNTHQKLVEENVFNLVSNKVKTKQGARQSPEGSQVSLNL : *. * :**.**** ** ***.**::*.: *.: *:** :: :. ::**.: ENSMUSP00000067516/1-907 ARHKTENSFSDSTHKQSVCERIRKDHCEHQGTSSSDSKENHAQSFETPCSSVSSEDTQDA ENSRNOP00000049813/1-910 ERHKTENLFSESTHKHTVCERRREYHLEHQETNGSDSKENCAQSFETPCSSVSSETIQDT ENSP00000356471/1-900 TRQKTEHLLSDFTYKRTVHEWKRKHHYDHQESNDSHSRENLTQSFEAPCCSVSSESIQDA ENSCPOP00000012840/1-908 TRHKVEHLLRDSTYKQTVREHKRKY-LEHQESNHSSIKENLTQTFEAPCSSVSPESIQDT XP_004921223.1/1-852 TRHKDEHLLFDSTYKQTVCDHKRKY-NEHQERNDSSSKKNLTQSFEAPCSSVSPENIQDT *:* *: : : *:*::* : *: :** . * ::* :*:**:**.***.* **: ENSMUSP00000067516/1-907 DEEMQIVEELHAARVGRSVDLPVVPPSGELMSMEIDLVDEDAHPSA---AHTASDTK-LL ENSRNOP00000049813/1-910 DEEMQIVEELHAARVGKSVDLPAGPPSGELMSMEIDLVEDDVHSSADILSNTASDKK-LL ENSP00000356471/1-900 DQEMQIVEELHAARVGKSVDLP-----GELMSMEIDL-EDDVHSSS---ANNTSDRK-LL ENSCPOP00000012840/1-908 DQEMQIVEELHAARVGKSVDIPVVPLSGELMSMEIDLAEDDVHFSA--VANIASDKKFLL XP_004921223.1/1-852 DQEMQIVEELHAARVGKSVDLTVVPPSGELMSMEIDLVEDDVHSSA---ANTVSDKKLLL *:**************:***:. ********** ::*.* *: :: .** * ** ENSMUSP00000067516/1-907 IVMDTNVLMNHLKFVKILKTTEIPGFDTLVLIIPWVVIQELDRMKAGKLLKHVQHKAVPA ENSRNOP00000049813/1-910 IVIDTNILMNHLKFVRILKTTEIPGFDTLVLIIPWVVMQELDRMKAGKLLKHVQHKAVPA ENSP00000356471/1-900 IVIDTNILMNHLKFVRILKTTEVPGFDKLVLIIPWVVMQELDRMKEGKLLKRAQHKAIPA ENSCPOP00000012840/1-908 VVVDTNILMNHLKFVRILKTTEISGFDRLVLIIPWVVVQELDRMKAGKLLKHAQHKAIPA XP_004921223.1/1-852 IVIDTNILMNHLKFVRILKTTEISGFDRLVLIIPWVVVQELDRMKAGKLLKHAQHKAIPA :*:***:********:******:.*** *********:******* *****:.****:** ENSMUSP00000067516/1-907 IHFINNSLKSQDRKLWGQSLQLASQKLYGLSDENNDDRVLKCCLQYQQLFPCSLVILCTD ENSRNOP00000049813/1-910 IHFINDSLKSQDRKLWGQSLQLASQKLYGLSDENNDDRVLKCCLQYQELFPCSLVILCTD ENSP00000356471/1-900 VHFINDSLKNQDRKLWGQSIQLASQKHYGLSDENNDDRVLKCCLQHQELFPCSFVILCTD ENSCPOP00000012840/1-908 VHFINDSLKNQDRKLWGQSIQLASQKLYGLSDENNDDRVLKCCLQYQELFSSSLVILCTD XP_004921223.1/1-852 VHFINNSLKSQDRKLWGQSIQLASQKLYGLSDENNDDRVLKCCLQYQELFPSSLVILCTD :****:***.*********:****** ******************:*:**..*:****** ENSMUSP00000067516/1-907 DRNLRTKGLISGVKSLSKEDLDTEILNLTLNTDLCHQPCISKQQLNAEVPPAKETPKEGA ENSRNOP00000049813/1-910 DRNLRSKGLISGVKSLSKEELDTEILNLTLNTDLCHQPYISKQQLKAEVPPTEETSKEES ENSP00000356471/1-900 DRNLRNKGLISGVKSLSKEELSAELLHLSLNTDVCHQPCIPKQQLKAETTPLKESYKEES ENSCPOP00000012840/1-908 DRNLRSKGLVSGVKSLSKEELSAELLTLSLNTDVCHQPCISKQQLKEEAKPVEETSEEKS XP_004921223.1/1-852 DRNLRSKGLISGVKSLSKEELSAELLTLSLNADVCHQPCISKQQLKAEAKPVEETSEKKS *****.***:*********:*.:*:* *:**:*:**** *.****: *. * :*: :: : ENSMUSP00000067516/1-907 ANSGLSILLERIICDLEKCLGTALSSILETEMKIAFGNLWMEVLYLKPPWTLINLLQCFK ENSRNOP00000049813/1-910 TNSGLSILLERIICDLEKCLGTALSSILETEMKIAFGNLWMEVLYLKPPWTLINLLQCFK ENSP00000356471/1-900 TNSGLSILLESIVSDLEKSLGTGLSSILETEMKIAFGNLWMEILYLKPPWTLLHLLQCFK ENSCPOP00000012840/1-908 TNSGLSIVLERIITDLERSLGTALSSILETEMKIAFGNLWIEMLYLKPPWTLIHLLQCFK XP_004921223.1/1-852 ANSGLPIVLERLISDLERSLGTALSSILETEMKIAFGNLWMEMLYLKPPWTLIHLLQCFK :****.*:** :: ***:.***.*****************:*:*********::****** ENSMUSP00000067516/1-907 KHWLAVFGLVMENNLLVTVESLYENLCK-ANKAVDFTTVKFLLQDSKSLLHAFSTRSNYD ENSRNOP00000049813/1-910 KHWLAVFGLVMENNLLVTIESLYDNLSK-ANKAVDFTTVKFLLQDSKSLLHAFSTRSNYD ENSP00000356471/1-900 KHWLAVFGLVMEKNLLLTIESLYKNLRK-ANKAVDFTTVKFLLQDSRSLLHAFSTRSNYD ENSCPOP00000012840/1-908 KHWFAVFGLVMEKNLLLTVESLYENLCKAANNAVDFTTVKFLLQDSKSLLHAFSIRSNYD XP_004921223.1/1-852 KHWLAVFGLVMEKNLLLTVESLYENFCK-ANNAVDFTTVKFLLQDSKSLLHAFSTRSNYD ***:********:***:*:****.*: * **:**************:******* ***** ENSMUSP00000067516/1-907 GVLPQTFAQVNKLLQVLAEVKTKLKPSSSESTRSKEQEDTSLVKLHNQDVNVFLDSNLPQ ENSRNOP00000049813/1-910 GILPQTFAQVNKLLQVLAEVKTKLKPNSSESTMSKKQEDT-LMKLHNQEVTVFLDSHPPQ ENSP00000356471/1-900 GILPQTFAQVNNLLQTFAEVKTKLKPNSSENTVTKKQEGTSLKNSHNQEITVFSSSHLPQ ENSCPOP00000012840/1-908 GILPQAFAQVSRLLQTFAEVKTKFKSNSSENAMNKTQEDTPLMKSQNQEISVSSVSHLLQ XP_004921223.1/1-852 GILPQAFAQISRLLQTFAEVKTKLKPNSSENTMSKTPEDAPLMKSHNQEITVFSGSHLPQ *:***:***:..***.:******:*..***.: .* *.: * : :**::.* *: * ENSMUSP00000067516/1-907 ATRHQEIWSVLESVWMSIYQNSTDVFQTLDSSSTLTTSKIASFEEAFVYLQKLMVAVKDI ENSRNOP00000049813/1-910 FTRHQEIWSVLENVWTSIYQNSTDVFQTLDSSSTLTTSKIASFEEAFIYLQKLMVAVKDI ENSP00000356471/1-900 PSRHQEIWSILESVWITIYQNSTDVFQRLGSNSALTTSNIASFEEAFICLQKLMAAVRDI ENSCPOP00000012840/1-908 PNRHQEIWSVLENVWITIYQNSTDVFQRLNSDSALTISKIASFEEAFIYLQKLMAAVKDI XP_004921223.1/1-852 SNRHQEIWSVLENVWITIYQNSTDVFQKLNSNAALTTSKIASFEEAFMYLQKLMAAVKDI .*******:**.** :********** *.*.::** *:********: *****.**:** ENSMUSP00000067516/1-907 LEGIQRILAPNSNYQDVETLYNFLIKYEVNKNVKFTARELYDCV-SQTEYRERLTIGCRQ ENSRNOP00000049813/1-910 LEGIQRILAPNSNCQDVETLYNFLIKYEVNKNVRFTAQELYDCV-SQTEYREKLTIGCRQ ENSP00000356471/1-900 LEGIQRILAPNSNYQDVETLYNFLIKYEVNKNVKFTAQEIYDCV-SQTEYREKLTIGCRQ ENSCPOP00000012840/1-908 LEGIQRILAPNSNYQDIETLYNFLIKYEVINIVEFTAQGTPMIVFSQTEYREKLTIGCRQ XP_004921223.1/1-852 LEGIQRILAPNSNYQDIETLYNFLIKYEVNKHVTFTAQELYDCV-SQTEYREKLTIGCRQ ************* **:************ : * ***: * *******:******* ENSMUSP00000067516/1-907 LIEMECTMQQCSASVYMEARSRGWCEDMLNNRP ENSRNOP00000049813/1-910 LIEMEYTMQQCSASVYMEAASRGWCEGMLNSRT ENSP00000356471/1-900 LVEMEYTMQQCNASVYMEAKNRGWCEDMLNYRI ENSCPOP00000012840/1-908 LVEMECAMQQCNASVYMGARHRGW--------- XP_004921223.1/1-852 LVEMECAMQQCNASVYMGAKNRGWCEDTFSCRT *:*** :****.***** * ***