CLUSTAL W(1.81) multiple sequence alignment ENSCPOP00000012435/1-883 -----------------------KGKRWEETSPPPPLPPNRGIPACWRGPKETGAKETAF XP_004843427.1/1-834 ------------------------------------------------------------ ENSP00000443824/1-936 MRPRSGGRPGATGRRRRRLRRRPRGLRCSRLPPPPPLPLLLGLLLAAAGPGAARAKETAF ENSMUSP00000105493/1-913 MRPRSGGRPGAPGRRRRRLRRGPRGRR---LPPPPPLPLLLGLLLAAAGPGAARAKETAF ENSRNOP00000064059/1-668 ------------------------------------------------------------ ENSCPOP00000012435/1-883 VEVVLFESSPSGDYTTYTTGLTGRFSPAGATLSAEGEIVQMHPLGLCNNNDEEDLYEYGW XP_004843427.1/1-834 ----------------------------------------MHPLGLCNNNDEEDLYEYGW ENSP00000443824/1-936 VEVVLFESSPSGDYTTYTTGLTGRFSRAGATLSAEGEIVQMHPLGLCNNNDEEDLYEYGW ENSMUSP00000105493/1-913 VEVVLFESSPSGDYTTHTTGLTGRFSRAGAMLSAEGEIVQMHPLGLCNNNDEEDLYEYGW ENSRNOP00000064059/1-668 ----------------------------------------MHPLGLCNNNDEEDLYEYGW ******************** ENSCPOP00000012435/1-883 VGVVKLEQPELDPKPCLTVLGKAKRAVQRGATAVIFDVSENPEAIDQLNQGSEDPLKRPV XP_004843427.1/1-834 VGVVKLEQPELDPKPCLTVLGKAKRAVQRGATAVIFDVSENPEAIDQLNQGSEDPLKRPV ENSP00000443824/1-936 VGVVKLEQPELDPKPCLTVLGKAKRAVQRGATAVIFDVSENPEAIDQLNQGSEDPLKRPV ENSMUSP00000105493/1-913 VGVVKLEQPELDPKPCLTVLGKAKRAVQRGATAVIFDVSENPEAIDQLNQGSEDPLKRPV ENSRNOP00000064059/1-668 VGVVKLEQPELDPKPCLTVLGKAKRAVQRGATAVIFDVSENPEAIDQLNQGSEDPLKRPV ************************************************************ ENSCPOP00000012435/1-883 VYVKGADAIKLMNIVNKQKVARARIQHRPPRQPIEYFDMGMFLAFFVLVSLASLIFLVRI XP_004843427.1/1-834 VYVKGADAIKLMNIVNKQKVARARIQHRPPRQPIEYFDMGMFLAFFVLVSLASLIFLVRI ENSP00000443824/1-936 VYVKGADAIKLMNIVNKQKVARARIQHRPPRQPTEYFDMGIFLAFFVVVSLVCLILLVKI ENSMUSP00000105493/1-913 VYVKGADAIKLMNIVNKQKVARARIQHLPPRQPTEYFDMGIFLAFFVVVSLVCLILLVKI ENSRNOP00000064059/1-668 VYVKGADAVKLMNIVNKQKVARARIQHLPPRQPTEYFDMGIFLAFFVVVSLVCLILLVKI ********:****************** ***** ******:******:***..**:**:* ENSCPOP00000012435/1-883 KLNQRRQQNSMNRLAVQALEKMETRKFNSKSKGRREGSCGALDTLSSSSTSDCAICLEKY XP_004843427.1/1-834 KLNQRR-QNSMNRLAVQALEKMETRKFNSKSKGRREGSCGALDTLSSSSTSDCAICLEKY ENSP00000443824/1-936 KLKQRRSQNSMNRLAVQALEKMETRKFNSKSKGRREGSCGALDTLSSSSTSDCAICLEKY ENSMUSP00000105493/1-913 KLKQRRSQNSMNRLAVQALEKMETRKFNSKSKGRREGSCGALDTLSSGSTSDCAICLEKY ENSRNOP00000064059/1-668 KLKQRRSQNSMNRLAVQALEKMETRKFNSKSKGRREGSCGALDTLSSGSTSDCAICLEKY **:*** ****************************************.************ ENSCPOP00000012435/1-883 TDGEELRIIPCTHRFHRKCVDPWLLQHHTCPHCRHNIIEQKGSPGAMYVETSNLARGRQQ XP_004843427.1/1-834 TDGEELRVIPCTHRFHRKCVDPWLLQHHTCPHCRHNIIEQKGSPGAVCVETSNLARSRQQ ENSP00000443824/1-936 IDGEELRVIPCTHRFHRKCVDPWLLQHHTCPHCRHNIIEQKGNPSAVCVETSNLSRGRQQ ENSMUSP00000105493/1-913 IDGEELRVIPCTHRFHRKCVDPWLLQHHTCPHCRHNIIEQKGNPGAVCVETSNLTRGRQP ENSRNOP00000064059/1-668 IDGEG----------HKKG------ERRPCPTWRPSLV---------------------- *** *:* :::.** * .:: ENSCPOP00000012435/1-883 RVTLPIHYPGRVHRTNAIPAYPTRTTMDSHGNPVTLLSMDQHGEQSLYSPQTPTYISGYP XP_004843427.1/1-834 RVTLPVHYPGRVHRTNAIPAYPTRTSMDSHGNPVTLLSMDRHGEQSLYPPQTPTYVRGYP ENSP00000443824/1-936 RVTLPVHYPGRVHRTNAIPAYPTRTSMDSHGNPVTLLTMDRHGEQSLYSPQTPAYIRSYP ENSMUSP00000105493/1-913 RVTLPVHYPGRVHRTNAIPAYPTRTSMDSHGNPVTLLTMDRHGEQNLYSPQTPTYVRGYP ENSRNOP00000064059/1-668 --------------------FPGAAELGTX-------------------XXXXXXXXXXX :* : :.: ENSCPOP00000012435/1-883 PLHLDHTLAAHRCSLEHRAYSPAHGFRRPKYSSRSFSKATCFSQYETMYQHYYFQGLSYP XP_004843427.1/1-834 PLHLDHTLATHHCGLEHRAYSPAHPFRRPKFSSRSFSKAACFSQYETMYQHYYFQGLSYP ENSP00000443824/1-936 PLHLDHSLAAHRCGLEHRAYSPAHPFRRPKLSGRSFSKAACFSQYETMYQHYYFQGLSYP ENSMUSP00000105493/1-913 PLHLDHTLAPHRCSLEHRAYSPAHPFRRPKFSSRSFSKAACFSQYETMYQHYYFQGLSYP ENSRNOP00000064059/1-668 XXXXXHTLAPHRCSLEHRAYSPAHPFRRPKFSSRSFSKAACFSQYETMYQHYYFQGLSYP *:**.*:*.********** ***** *.******:******************** ENSCPOP00000012435/1-883 EQEGPPPPTLPPRGPSRAFPSSGGSSLLFPTVVHMAPPSHLESGSMSSFSCYHGHRSMCS XP_004843427.1/1-834 EQEGQPPPSLPPRGPSRVFPPNGGSSLLFPTVVHMVPPTHLESGSTSSFSCYHGHRSMCS ENSP00000443824/1-936 EQEGQSPPSLAPRGPARAFPPSGSGSLLFPTVVHVAPPSHLESGSTSSFSCYHGHRSVCS ENSMUSP00000105493/1-913 EQEGQTIPSVTPRGQSRAFPPSGASSLLFPTMVHVAPPTHVESGSTSSFSCYHGHRSVCS ENSRNOP00000064059/1-668 EQESQPVPSVTPRGQSRAFPPSGGSSLLFPTMVHMAPPAHVESGSTSSFSCYHGHRSVCS ***. . *::.*** :*.**..*..******:**:.**:*:**** ***********:** ENSCPOP00000012435/1-883 GYLADCPGSD--SSSSSGQCHCSSSDSVVDCTEVSNQGVYGSCSTFRSSLSSDYDPFIYR XP_004843427.1/1-834 GYLADCPGSD--SSSSSGPCHCSSSDSVMDCTEVSNQGVYGSCSTFRSSLSSDYDPFIYR ENSP00000443824/1-936 GYLADCPGSDSSSSSSSGQCHCSSSDSVVDCTEVSNQGVYGSCSTFRSSLSSDYDPFIYR ENSMUSP00000105493/1-913 GYLADCPGSD-SSSNSSGQCRCSSSDSVVDCTEVSNQGVYGSCSTFRSSLSSDYDPFIYR ENSRNOP00000064059/1-668 GYLADCPGSD-SSSNSSGQCRCSSSDSVVDCTEVSNQGVYGSCSTFRSSLSSDYDPFIYR ********** **.*** *:*******:******************************* ENSCPOP00000012435/1-883 ----------------SRGPAVCLEGSLPPEELLAAHSHGAGKGEPWPGPASPSGDQLST XP_004843427.1/1-834 SRSPCHTSEAGASGSSSRAPAVCLEGSLPPEELLTAHSYGAGKGEPWPGPASPSGDQLST ENSP00000443824/1-936 SRSPCRASEAGGSGSSGRGPALCFEGSPPPEELPAVHSHGAGRGEPWPGPASPSGDQVST ENSMUSP00000105493/1-913 ----------------SRGPAVHLEGSPPPEELPAGHSQSAGRGEPWLGPASPSGDQLST ENSRNOP00000064059/1-668 ----------------SRGPAVHLEGSPPPEELPAAHNQGAGRGEPWLGPASPSGDQLST .*.**: :*** ***** : *. .**:**** *********:** ENSCPOP00000012435/1-883 CSLEMNYSSNSSLEHRGPASCTSDVGLEASSGAALDLRRTWKGAREGPSCVCCCEPQPFA XP_004843427.1/1-834 CSLEMNYSSNSSLEHRGPTSSTSDVGLEGSPGAALDLRRTWKGGLEGPSCVCCCEPQPFA ENSP00000443824/1-936 CSLEMNYSSNSSLEHRGPNSSTSEVGLEASPGAAPDLRRTWKGGHELPSCACCCEPQPSP ENSMUSP00000105493/1-913 CSLEMNYSSNSSLEPRGPNSSTSEVGLEVSPGAALDLRRTWKGGPEGPSCACCFEPQPFP ENSRNOP00000064059/1-668 CSLEMNYSSNSSLEPRGPNSSTSEVGLEVSPGAALDLRRTWKGGPEGPSCACCFEPQPVT ************** *** *.**:**** *.*** ********. * ***.** **** . ENSCPOP00000012435/1-883 LGPGVGAPGSCSTLFLSAPLHEGCSHTGGELQPGSSQSLSGLHPDHLPRIDGVKYEGLPC XP_004843427.1/1-834 LGPGAGAAGNGSTLFLSAPLHEGCSHTGGELQPGSSQGLYGLHPDHLPRIDGVKYEGLPC ENSP00000443824/1-936 AGPSAGAAGS-STLFLGPHLYEGSGPAGGEPQSGSSQGLYGLHPDHLPRTDGVKYEGLPC ENSMUSP00000105493/1-913 PGSGIETSAGGSSLFLGPRLLEDCNPPSGEPQLGSSQGLYGLHSDHYPRTDGVKYEGLPC ENSRNOP00000064059/1-668 LGSGIGTTAGGSSLFLGPRLLEDCNPASGEPQLGSSQGLYGLHSDHYPRTDGVKYEGLPC *.. :... *:***.. * *... ..** * ****.* ***.** ** ********** ENSCPOP00000012435/1-883 CFYEEKQVAHGGGGGSGCYTEDYSVTVQYTLAEEPPPSCYPGAQDLNQRIPIIPEDVDCD XP_004843427.1/1-834 CFYEEKQVAHGGGGGSGCYTEDYSVTVQYTLAEEPPPSCYSGAQDLSQRIPIIPEDVDCD ENSP00000443824/1-936 CFYEEKQVARGGGGGSGCYTEDYSVSVQYTLTEEPPPGCYPGARDLSQRIPIIPEDVDCD ENSMUSP00000105493/1-913 CFYEEKQVAHSAGRGNGCYTEDYSVSVQYTLTEEPPPSCYAGPRDLSQRIPIIPEDVDCD ENSRNOP00000064059/1-668 CFYEEKQVAHSAGRGNGCYTEDYSVSVQYTLTEEPPPSCYAGARDLSQRIPIIPEDVDCD *********:..* *.*********:*****:*****.**.*.:**.************* ENSCPOP00000012435/1-883 LGLPLGCLGTHSLSPWGGTLGLNALRPPRGLGTAQEEEQAPFYQADVPLQPDCPPEEAGA XP_004843427.1/1-834 LGLPLDCQGTPSLRPWGRTPGLDALRPHRSLGTAQEEEQAPCYQADVLLQPGCLPEGAGA ENSP00000443824/1-936 LGLPSDCQGTHSLGSWGGTRGPDTPRPHRGLGATREEERALCCQARALLRPGCPPEEAGA ENSMUSP00000105493/1-913 LGLPQDCHGMHNHSPWGGALSLDVPRLHWSLGTTREEEQAPCYQAEV--QPGCSPEEAGA ENSRNOP00000064059/1-668 LGLPQDCQGRHSHSPWGGALGL-------------------------------------- **** .* * . .** : . ENSCPOP00000012435/1-883 TRSNLPSDPPDTQKSNAPGAEAAG------------- XP_004843427.1/1-834 TRASLPSAPQDTQESNAPGAEAAGPGSRPAEGSGTGT ENSP00000443824/1-936 VRANFPSALQDTQESSTTATEAAGPRSHSADSSSPGA ENSMUSP00000105493/1-913 SRASLSSAPQDTQESHALAAEASGPGSGPGIGTGA-- ENSRNOP00000064059/1-668 -------------------------------------