CLUSTAL W(1.81) multiple sequence alignment ENSMUSP00000102167/1-1004 MEEYEEFCEKALGRAQEASLSTGSFLPAQAESVSLIRFHGVAVLSPLLTIEKRKKIQEEK ENSRNOP00000035030/1-960 -----------------------------------------------LTIEKREKIQQEK ENSP00000370803/1-1012 MEEYEKFCEKSLARIQEASLSTESFLPAQSESISLIRFHGVAILSPLLNIEKRKEMQQEK ENSCPOP00000012377/1-1011 MEEYEEFCEKTLARIQEASLSTESFLPAQAESISLIRFHGVAVLSPLLNTEKRNEIQQEK XP_004855866.1/1-1012 MEEYEEFCEKTLARIQEASLSTESFLPAQSESISLIRFHGVAVLSPLLNIEKRKEIQQEK *. ***:::*:** ENSMUSP00000102167/1-1004 QKALDVQSRKQANRKKALLTRVQEILENVQVRKAPNASDFDQWATETIYSNPEVTDLNVP ENSRNOP00000035030/1-960 QKALDVQTRKQANRKKALLTRVQEILENVQVRKAPNASDFDQWATETIASNSEVTGLSVP ENSP00000370803/1-1012 QKALDVEARKQVNRKKALLTRVQEILDNVQVRKAPNASDFDQWEMETVYSNSEVRNLNVP ENSCPOP00000012377/1-1011 QKALDIEARKQVNRKKALLTRVQEILENVQVRKARKASDFDQWETNTVYSNSEVTNLNVP XP_004855866.1/1-1012 QKALNVEARKQVNRKKALLTRVQEILENVQVRKARKASDFDQWEAETAYSNAEVRNLNVP ****::::***.**************:******* :******* :* **.** .*.** ENSMUSP00000102167/1-1004 VRVPNSLPSPTEHCTSVKLEKITGLLPVNNEDQQTPKRVGLPGDSEVSGSLRQCESPESR ENSRNOP00000035030/1-960 VTVPSDLLSPTEHCTSGKLGKTTGLLPVNNEDQQSPERMGLPKDSEVFGSLKQCESPGSR ENSP00000370803/1-1012 ATFPNSFPSHTEHSTAAKLDKIAGILPLDNEDQCKTDGIDLARDSEGFNSPKQCDSSNIS ENSCPOP00000012377/1-1011 ATFPNSLPSATDHSALAESEQTAGVLLMDNEDQHKPNGIELAKDTEGFNSPKQCDSSNSC XP_004855866.1/1-1012 AVFPNSLPSPSEHPTLARLEKTAGVSPTDNEDQQRPNGIELARDTEGSNSPKQCDKSSSS . .*..: * ::* : . : :*: :**** .. : *. *:* .* :**:.. ENSMUSP00000102167/1-1004 QAEDGAALRLSSASPQETIISD--VLGKEEQDPSCLAEVTPDPYIMSLQNLMKRSKEYVE ENSRNOP00000035030/1-960 WAENGAAPRLSSASSQETVISDDPLLAKEEQEPSCLAEVTPDPYIISLQNLMKRSKEYVE ENSP00000370803/1-1012 HVENEAFPKTSSATPQETLISDGPFSVNEQQDLPLLAEVIPDPYVMSLQNLMKKSKEYIE ENSCPOP00000012377/1-1011 DTESETSPKISSATSQGTLISDVLISTTEEQELPVLAEVTPDPYIMSLQNLMKKSKEYLE XP_004855866.1/1-1012 QAETETSPKI-SATPKGTPTSDSLVSRAEEQDPPVLAEVTLDPYVMSLQNLMKKSKEYTE .* : : **:.: * ** . *:*: . **** ***::*******:**** * ENSMUSP00000102167/1-1004 RELSSRSLRNSLKRSVNETHSDRENDAAKASDCVKEKAPPMPIGRHCGSAIPDKPSLNKS ENSRNOP00000035030/1-960 REQSSWSLRSSLKKSVHETHSDKENDAAKASDCVKEKAPPMPVGRHCGSAIPDKPSLNKS ENSP00000370803/1-1012 REQSRRSLRGSINRIVNESHLDKEHDAVEVADCVKEKGQLT--GKHCVSVIPDKPSLNKS ENSCPOP00000012377/1-1011 REQSRRSLRSSTKRSVNESHSDKENDAAKVSDCVKEKALVI--GKHCGSVIPDKPSLNKS XP_004855866.1/1-1012 REQSGRSLRSSTRRNINESPSDKENDAVTVSECVKEKAPLT--GKRCGSAIPDKLSLNKS ** * ***.* .: ::*: *:*:**. .::*****. *::* *.**** ***** ENSMUSP00000102167/1-1004 NVLLQGA-SQASSMGTAGLASFSKIDLPAGAAPPAAPDAGSDFTVIPTFVTENKV-KSLK ENSRNOP00000035030/1-960 NVLLQGA-SQASSLGTSVLASFLKTDLPVGTGPPTVPDAESDFKVIPTFVTENKV-KSLI ENSP00000370803/1-1012 NVLLQGASTQASSMSMPVLASFSKVDIPIRTGHPTVLESNSDFKVIPTFVTENNVIKSLT ENSCPOP00000012377/1-1011 NVLLQGASSQAGSTNTSVSGSFSKVDIPIQTGHPTVLDSEADFKVIPTSITENNVIKSLT XP_004855866.1/1-1012 NVLLQGACSQPGSTNTSVLASFSKVDIPVQTGHPTVPHSEADFKVIPTFITENNVIKSLT ******* :*..* . . .** * *:* :. *:. .: :**.**** :***:* *** ENSMUSP00000102167/1-1004 GPYAKLPSPEPSMSPTMHRRHSRSASACQILINNPVNACELSPKGKEEAVDRTAPAAAET ENSRNOP00000035030/1-960 GPYAKLPSPEPSMSPTMHRRHSRSSSACQILINNPVNACELSPKGKEEAVDRIAPAAAE- ENSP00000370803/1-1012 GSYAKLPSPEPSMSPKMHRRRSRTSSACHILINNPINACELSPKGKEQAMDLIIQDTDEN ENSCPOP00000012377/1-1011 GSYAKLPSPEPSMSPKMHRRRSRPPSACHILINNPINACELSPKGKEQTVDLIIPDTDEK XP_004855866.1/1-1012 GSYAKLPSPEPSVSPKMHRRHSRPSSACHILINNPINACELSPKGKEQMVNIIIPDTDEK *.**********:**.****:**..***:******:***********: :: : * ENSMUSP00000102167/1-1004 TNESETVPKSPTDLTGVCSSNVSATKITSESTREMVVGKPSQRQQALGAHLGNNVTVERS ENSRNOP00000035030/1-960 TNESEIVPKPPTDLTGVGSSKVSATKVMSDTIREMVMGKPSQVHQALGNQLGNNVTVEQF ENSP00000370803/1-1012 TNVPEIMPKLPTDLAGVCSSKVYVGKNTSEVKEDVVLGKSNQVCQSSGNHLENKVTHGLV ENSCPOP00000012377/1-1011 TTISETVPKLPIDLAGVCSSKIYVCKNAIEAIEDATVGKSSQVCQSLGNQLENKVTHGLA XP_004855866.1/1-1012 TSVSETVPKLPLDLAGVCSSKTYVSKNASEAIEDVAVGKSSQVCQSLGNQLENKVTHGLF *. .* :** * **:** **: . * : .: .:**..* *: * :* *:** ENSMUSP00000102167/1-1004 AMEGPFIADDRGAQKVDGTCMAVPKLHELQPS-SQCVSSQTLEDVCELKSASLLAKNSCN ENSRNOP00000035030/1-960 AMEGPFIPDGRGMQKVDGTCIAVPKLHELQPT-SQCVSSQTLEDACGLKAASVLAKNSCN ENSP00000370803/1-1012 TVEGQLTSDERGAHIMNSTCAAMPKLHEPYAS-SQCIASPNFGTVSGLKPASMLEKN-CS ENSCPOP00000012377/1-1011 VVEGQLISDARGAHKSNTPCSTGPMSHEPCATASQCIASQNLGTVSGFKSVSMLEKNSCN XP_004855866.1/1-1012 AVEGQLTSDARGTHKMNNTCSTGPKLQGPYVIPSQCIASQNLETVSGFRSGSVLEKNSCN .:** : .* ** : : .* : * : ***::* .: .. ::. *:* ** *. ENSMUSP00000102167/1-1004 LQMELNKSYDVKHPSPLLTQTQTSRQQMDTPPVFRGNEQFVDNSFEKVKRRLDLDVDSLQ ENSRNOP00000035030/1-960 VQMELNKSYDVKRPSPLLMQTQNSRQQMDTPPVPRGNEQFVDNSFEKVKRRLDLDVDSLQ ENSP00000370803/1-1012 LQTELNKSYDVKNPSPLLMQNQNTRQQMDTPMVSCGNEQFLDNSFEKVKRRLDLDIDGLQ ENSCPOP00000012377/1-1011 SQIELNKSYHVKNPSPLLMQNQNTTPPMDIPMVSCGNEQLLDNSFEKVKRRLDLDMDGLQ XP_004855866.1/1-1012 SQMELNKSYNVKNPSPLLMQNQNPGQQMDTPMVSCGNEQLLDNSLEKVKRRLDLDMDGVQ * ******.**.***** *.*.. ** * * ****::***:**********:*.:* ENSMUSP00000102167/1-1004 KENCPYIITAGVAEQERDRLLERRYPKG-FVHINKNKMLETSPKEGQELLKSKMLAFEEM ENSRNOP00000035030/1-960 KENCPHILTAGSAEQERERPPERRYPKG-SVYGNKNKMLETSPKEGQELLKSKMLAFEEM ENSP00000370803/1-1012 KENCPYVITSGITEQERQHLPEKRYPKG-SGFVNKNKMLGTSSKESEELLKSKMLAFEEM ENSCPOP00000012377/1-1011 KENCPYVITT----EEQRHLPEKRYPAG-SFYSHKNKILETSTKEGEDILKSRMLAFEEM XP_004855866.1/1-1012 KENCPYVITTRIAEQERQYLPEKRYPKGSSLYIYKNKILETSTK-GEELLKSKMLAFEEM *****:::*: :*: *:*** * . ***:* **.* .:::***:******* ENSMUSP00000102167/1-1004 RKRLEEQHAQQLSLLIAEQEREQEQLQKEIEEQEKMLKEK-AVTTDVSDL--NSA--LEW ENSRNOP00000035030/1-960 RKRLEEQHVQQLSLLIAEQEREQEQLQKEIEEQEKMLKEK-AVTTDVSGL--NSALELEW ENSP00000370803/1-1012 RKRLEEQHAQQLSLLIAEQEREQERLQKEIEEQEKMLKEKKAMTAEASELDINNAVELEW ENSCPOP00000012377/1-1011 RKRLEEQHAQQLSLLIAEQEREQERLQKEIEEQEKMLKEKEAITAEVSELNINNTVDLEW XP_004855866.1/1-1012 RKRLEEQHAQQLSLLIAEQEREQERLQKEIEEQEKILKEKKVITTEVSELNINHTVELEW ********.***************:**********:**** .:*::.* * * : *** ENSMUSP00000102167/1-1004 RQRTDSALLETMLSQVDSLQTSN--NSGFITSALQYSFGSAGEAPFYLWGSLTSGVTRVS ENSRNOP00000035030/1-960 RKRSDPAFLETMLSQVDSLQTSN--NSGFLSSALQYSFGSASEVPLYLRGSLTSGVTKLS ENSP00000370803/1-1012 RKISDSSLLETMLSQADSLHTSNSNSSGFTNSAMQYSFVSANEAPFYLWGSSTSGLTKLS ENSCPOP00000012377/1-1011 RKISDSGLLETMMSQVDSFRTSNSHSSGFTNSGLQYSCGSANETPFYLWGSSTSGMTRLS XP_004855866.1/1-1012 RKISDSGLLETVLSQVDSFRTSNSQNSGFTNSALQYSCGSANEAPFYLWGS-TSGATKLS *: :*..:***::**.**::*** .*** .*.:*** **.*.*:** ** *** *::* ENSMUSP00000102167/1-1004 GTRPCGRAQAKWSQVFNPEIHAKFNKITAVAKGFLTRKLMQTDKLKQLRQTVKDTMEFIR ENSRNOP00000035030/1-960 VTRPFGRAQPKWSQVFSPEIQAKFNKITAVAKGFLTRKLMQTDKLKQLRQTVKDTMEFIR ENSP00000370803/1-1012 VTRPFGRAKTRWSQVFSLEIQAKFNKITAVAKGFLTRRLMQTDKLKQLRQTVKDTMEFIR ENSCPOP00000012377/1-1011 VPRPFGRGQPRWSQVFNPEVQAKFNKITAMAKGFLTRRLMQTDKLKQLRQTVKDTMEFIR XP_004855866.1/1-1012 VPRPFGRGQPRCTQVFDPEVQVKFNKITAVAKGFLIRRLMQTDKLKQLRQTVKDTMEFIR .** **.:.: :***. *::.*******:***** *:********************** ENSMUSP00000102167/1-1004 SFQSEAPLKRGVVSAQDASLQERVLAQLRAALYGIHDIFFVMDAAERMSILHHDREARKE ENSRNOP00000035030/1-960 SFQSEAPLKRGVVSAQDASLQERVLAQLRAALYGIHDIFFVMDAAERMSILHHDREARKE ENSP00000370803/1-1012 SFQSEAPLKRGIVSAQDASLQERVLAQLRAALYGIHDIFFVMDAAERMSILHHDREVRKE ENSCPOP00000012377/1-1011 NFQSEAPLKRGIVSAQDASLQERVLAQLRAALYGIHDIFFVMDAAERMSILQHDREVRKE XP_004855866.1/1-1012 SFQSEAPLKRGIVSAQDASLQERVLAQLRAALYGIHDIFFVMDAAERMSILQHDREVRKE .**********:***************************************:****.*** ENSMUSP00000102167/1-1004 KLLRQMDKMKSPRVALSVATQKSLDRKKFMKVAEMGMPNKKFLLKQNPSET-RVLQPNQG ENSRNOP00000035030/1-960 KLLRQMDKMRSPRVALSVATQKSLDRKKFMKVAEMGMANKKFLLKQNPSET-RVLQPNQG ENSP00000370803/1-1012 KMLRQMDKMKSPRVALSAATQKSLDRKKYMKAAEMGMPNKKFLVKQNPSET-RVLQPNQG ENSCPOP00000012377/1-1011 KMLRQMDKMKSPRVALSAATQKSLDRKKYMKAAEMGMPNKKFLVKQSPSETSRVLQPNQG XP_004855866.1/1-1012 KMLRQMDKMKSPRVALSAATQKSLDRKKYMKVAEMRMPNKKFLVKQSPSET-RVLQPNQG *:*******:*******.**********:**.*** *.*****:**.**** ******** ENSMUSP00000102167/1-1004 QNAPVHRLLSRQGTPKTSVKGVVQNRQKPSQSRVPNRAPVSGAYAGKTQRKRPNVATI ENSRNOP00000035030/1-960 QNAPVHRLLSRQGTPKTSVKGVVQNRQKPSQSRVPNRAPVSGAYAGKTQRKRPNVATI ENSP00000370803/1-1012 QNAPVHRLLSRQGTPKTSVKGVVQNRQKPSQSRVPNRVPVSGVYAGKIQRKRPNVATI ENSCPOP00000012377/1-1011 QNAPVHRLLSRQGTPKTSVKGVIQNRQKPSQSRVPNRAPVSGVYAGKIQRKRPNVATI XP_004855866.1/1-1012 QNAPVHRLLSRQGTPKTSMKGVVQNRQKPSQSRVPSRAPVSGVYAGRIQRRRPNVATI ******************:***:************.*.****.***: **:*******