CLUSTAL W(1.81) multiple sequence alignment ENSCPOP00000012326/1-2471 ------------------------------------------------------------ XP_004840597.1/1-2786 -----------------MGHCTVLGVTNVYAEADSLTRGHGGTARPGPGSPMMSTAAPEA ENSP00000289672/1-2849 MAEEAAQNISDDQERCLQAACCLSFGGELSVSTDKSWGLHLCSCSPPGGGLWVEVYANHV ENSMUSP00000120803/1-2521 ------------------------------------------------------------ ENSRNOP00000006498/1-2529 ------------------------------------------------------------ ENSCPOP00000012326/1-2471 ------------------------------------------------------------ XP_004840597.1/1-2786 GSLEESGRQRRGCISAGHLWPFADTDSSLTTVAPHKTSVTITTVLGSGGPGSCRWQQWAP ENSP00000289672/1-2849 LLMSDGKCGCPWCALNGK--AEDRESQSPSSSASRQKNIWKTTSEAALSVVNEKTQAVVN ENSMUSP00000120803/1-2521 ------------------------------------------------------------ ENSRNOP00000006498/1-2529 ------------------------------------------------------------ ENSCPOP00000012326/1-2471 ------------------------------------------------------------ XP_004840597.1/1-2786 GEPEAPFSGTHESGERNIIPALLSVRMWSLSVRFMIADHSTHLIALSVAEELHELLAISH ENSP00000289672/1-2849 EKTQAPLDCDNSADRIPHKPFIIIARAWSSGGPRFHHRRLCATGTADSTFSALLQL---- ENSMUSP00000120803/1-2521 ------------------------------------------------------------ ENSRNOP00000006498/1-2529 ------------------------------------------------------------ ENSCPOP00000012326/1-2471 ------------------------------------------------------------ XP_004840597.1/1-2786 ADTPDRGGSSATGPYNLRTFPCCGWRQLLRSAEDPAKAPLLGVLTSGAPTGAAGPPQATT ENSP00000289672/1-2849 -----QGTTSAAAPCSLKMEASCCVLRLLCCAEDVATGLLPGTVTMETPTKVARPTQTSS ENSMUSP00000120803/1-2521 --------------------------------------------XFSNP----------- ENSRNOP00000006498/1-2529 ---------------------------------------------FSDP----------- ENSCPOP00000012326/1-2471 ------------------------------------------------------------ XP_004840597.1/1-2786 QPALLGGPPSGLPTVPRRPSSSCEPPGPVSFQEPTSKCRRPSETFLVQTVTVVLPAANCP ENSP00000289672/1-2849 QRVPLWPI---------------------------------------------------- ENSMUSP00000120803/1-2521 ------------------------------------------------------------ ENSRNOP00000006498/1-2529 ------------------------------------------------------------ ENSCPOP00000012326/1-2471 ------------------------------------------------------------ XP_004840597.1/1-2786 EPRASLAAAFDNPARLLTPTPVPPGDASGTPSDTLNPEVSACPHSSLGPLPGTARTPSLP ENSP00000289672/1-2849 ------------------------------------SHFPTSPRSSHGLPPGIPRTPSFT ENSMUSP00000120803/1-2521 -------------------------------------------------PPGISHTCNLS ENSRNOP00000006498/1-2529 -------------------------------------------------PPGISQTRNLS ENSCPOP00000012326/1-2471 -------------------------------------DVGARGPPALGFCVQLALGEALH XP_004840597.1/1-2786 GSPSGPQRPCRLTPCPPAAVLVRDPDNAAHPAACCSPDTDARAAPALGFRVHLASRAALR ENSP00000289672/1-2849 ASQSGSEILYPPTQHPPVAILARNSDNFMNPVLNCSLEVEARAPPNLGFRVHMASGEALC ENSMUSP00000120803/1-2521 ASWYHPESSSPLTQHPPRATLVTQPENVEHFAICCFPETDAQALPALGIRVHVASGTALC ENSRNOP00000006498/1-2529 ASWYHPESSCPLTQHPLGAVLATQPENAGHFATCCFPETDAKAPPALGIRVHAASRTALC :. *:. * **: *: * ** ENSCPOP00000012326/1-2471 LRVDFGDTTGTEIRLQDTTEAVAVTAFHQYRK---------------------------- XP_004840597.1/1-2786 LLVDFGDSVGAEVRLCSMTAATEVTAFHQYGK---------------------------- ENSP00000289672/1-2849 LMMDFGDSSGVEMRLHNMSEAMAVTAYHQYSKGIFFHLLHFQLDMSTYKEAETQNTTLNV ENSMUSP00000120803/1-2521 LLLDFGDNCGAQMRLCTLAGATTVTGYHQYRK---------------------------- ENSRNOP00000006498/1-2529 LLLDFGDNHGAEMKLSTVTGAATMTGYYQYRT---------------------------- * :****. *.:::* : * :*.::** . ENSCPOP00000012326/1-2471 ----------------------------EGVYTLRAAVRG-HQGHEVELGPYYVAAGHRA XP_004840597.1/1-2786 ----------------------------EGVYALRAAILG-HQGPQVELGPYYVAVTHGH ENSP00000289672/1-2849 YLCQSENSCLEDSDPSNLGYELISAFVTKGVYMLKAVIYNEFHGTEVELGPYYVEIGHEA ENSMUSP00000120803/1-2521 ----------------------------EGVYELKAVVHD-FHRAE-ELGPYYVDISHGN ENSRNOP00000006498/1-2529 ----------------------------EGVYKLKVVVSD-CHGADEELGPYYMDIGHGN :*** *:..: . : : ******: * ENSCPOP00000012326/1-2471 VSVLMNSSSIHRDEVLVLVGSHPRQKGTVVQHCVPGVASYNVSFLSGTQAGCSQAWPSVT XP_004840597.1/1-2786 VSVLMNTSSTHQNEVLTFAGSHPGQKGTGVTHRFPWLASCNVSFLSRARAGHSQAWHSVT ENSP00000289672/1-2849 VSAFMNSSSVHEDEVLVFADSQVNQKSTVVIHHFPSIPSYNVSFISQTQVGDSQAWHSMT ENSMUSP00000120803/1-2521 VSVFMNSSSIHDSEALSFADSLPQQRGTVVVHCFSSISSYNVSFISQTQVASGQAWCGVT ENSRNOP00000006498/1-2529 VSVFMNSSSIHNNESLAFANSLPQQEGTVVVHCFSSVSSYNVSFMSQTRVGSSQAWSGVT **.:**:** * .* * :..* *..* * * .. :.* ****:* ::.. .*** .:* ENSCPOP00000012326/1-2471 VRYQMQPVSVYTNGTMFATDTDITFVAVTKETAPLEFTWHFGDGAPVRTTSRSIQRRLSI XP_004840597.1/1-2786 VWYQMQPVSIYTNGTVFAEDADITFVAVTKETTALEFTWHFGDGPPVRTTSRSIRRRLGA ENSP00000289672/1-2849 VWYKMQSVSVYTNGTVFATDTDITFTAVTKETIPLEFEWYFGEDPPVRTTSRSIKKRLSI ENSMUSP00000120803/1-2521 VGYKMQSVSVYTNGTVFAANTNITFVAITEETIPLEFAWYFGENPPVMTTSRSIRRRLSV ENSRNOP00000006498/1-2529 VGYTMQSVSVYTNGTVFAADTNITFVAVTEETVPLEFTWYFGENPPVTTTSRSIRRRLSI * * **.**:*****:** :::***.*:*:** .*** *:**:..** ******::**. ENSCPOP00000012326/1-2471 PQWYRVTVTASGEVGSVVSEPRVLKAQRRIEANRLVSASTALVNTSVAFECRINFGTDVA XP_004840597.1/1-2786 PQWYWVTVAASGTMGSVVSAPHVLRVQRRVRANRLVSAPTALVNTSVAFECRINFGTDVA ENSP00000289672/1-2849 PQWYRVMVKASNRMSSVVSEPHVIRVQKKIVANRLTSPSSALVNASVAFECWINFGTDVA ENSMUSP00000120803/1-2521 PQWYRVKVKATSRIGSVVSEPHLIRVQKRIMANRLVSTASALVNANVSFECRLNFGTDVA ENSRNOP00000006498/1-2529 PQWYRVMVKATSRMGSVVSEPHLIRVQKRILANRLVSTASALVNANVSFECRLNFGTDVA **** * * *:. :.**** *::::.*::: ****.*..:****:.*:*** :******* ENSCPOP00000012326/1-2471 FRWDFGDGAVSLGTSSTSHIYSREGEFTVQVLAFNGVSAATLRTQLFVVREPCQPPPVRN XP_004840597.1/1-2786 FLWDFGDGTVHPGSSSTSHIYSREGEFTVHVLAFNNVSSASLRKQLFVVHQPCQPPPVKN ENSP00000289672/1-2849 YLWDFGDGTVSLGSSSSSHVYSREGEFTVEVLAFNNVSASTLRQQLFIVCEPCQPPLVKN ENSMUSP00000120803/1-2521 YLWNFGDDTIELGSSSSSHVYSREGEFTVEVLAFNNVSSTTLRKQLFIVREPCQPPPVKN ENSRNOP00000006498/1-2529 YLWNFGDGSIELGSSSSGHVYDREGEFTVEVLAFNNISSATLRKQIFIVQEPCQPPPVKN : *:***.:: *:**:.*:*.*******.*****.:*:::** *:*:* :***** *:* ENSCPOP00000012326/1-2471 MGPQKVQMWRAQPLRLGVTFEAAVLCDISRGLSYAWSLVDAEGSPVALPAAVSTHRQILV XP_004840597.1/1-2786 MGPGKVQVWRAQPLRLGVTFEAAVLCDISQGLAYTWSLEDTEGSPVALPAAVDTHRQSLM ENSP00000289672/1-2849 MGPGKVQIWRSQPVRLGVTFEAAVFCDISQGLSYTWNLMDSEGLPVSLPAAVDTHRQTLI ENSMUSP00000120803/1-2521 MGPAKVQIWRSQPLRLGVTFEAAILCNISQGLSYTWSFVSAEMTTVTLPTAVNTRRQTIM ENSRNOP00000006498/1-2529 MGPAKVQIWRSQPLRLGVTFEAAIICNISQGLSYTWSFVGAEATAVTLPAAVNTHRQTIM *** ***:**:**:*********::*:**:**:*:*.: .:* .*:**:**.*:** :: ENSCPOP00000012326/1-2471 LPGYTLVSGDYTAIAKVQIRGSAVHSNYTVGVEVWAQAPVAVISEGTHLFVPRAAGVPVT XP_004840597.1/1-2786 LPAYALDSGEYTATAKVRIQGTMVHSNYSVGVEVLARVPVAVISEGTHLFVPRAAREPVV ENSP00000289672/1-2849 LPSHTLEYGNYTALAKVQIEGSVVYSNYCVGLEVRAQAPVSVISEGTHLFFSRTTSSPIV ENSMUSP00000120803/1-2521 LPSYTLECGNYTAIAKVQIKGSMVYSNYCVGVEVRARAPVSVISEGTHIFISTATSTFII ENSRNOP00000006498/1-2529 LPSYTLECGNYTAVAKVQIKGSMVYSNYCVGVEVRARAPVSVISEGTHIFLSKATSTSII **.::* *:*** ***:*.*: *:*** **:** *:.**:*******:*.. :: : ENSCPOP00000012326/1-2471 LRGTLSYDPDHPGAALSYRWTCTAARSPGQPCFDGIGPHPLDSRAPTLTFTAEQLNRCCD XP_004840597.1/1-2786 LRGTQSFDPDHPGAVLSYHWTCTAARSPGRPCFDDTGPNQPDTRASIFSFAVERLSTCCD ENSP00000289672/1-2849 LRGTQSFDPDDPGATLRYHWECATAGSPAHPCFDSSTAHQLDAAAPTVSFEAQWLSDSYD ENSMUSP00000120803/1-2521 LRGAQSYDPDNPGAALRYHWTCTAASSPRWPCFDNSTSYQVDTQAPAISFPAKWLSECCD ENSRNOP00000006498/1-2529 LSGSQSYDPDNPGAALRYHWTCTAASSPIWPCFDDSTSYQMDTQAPAISFPAKWLSECCD * *: *:***.***.* *:* *::* ** ****. . *: *. .:* .: *. . * ENSCPOP00000012326/1-2471 QFLVTLTVASRGRSSSEAQVFLSTREDPAFRFLRLDRGSFRDTSINWNEAFSLRAVCDSC XP_004840597.1/1-2786 QFLLTLTVASRGQYSSEAQVFLSTRQDPGFRFLHISWLSFKDVYVNWNEELSLRAVCDDC ENSP00000289672/1-2849 QFLVMLRVSSGGRNSSETRVFLSPYPDSAFRFVHISWVSFKDTFVNWNDELSLQAMCEDC ENSMUSP00000120803/1-2521 QFLVTLTVSSRGQNSSQALMFLSTRPDLAFRFVHISWVNFRDISVNWNEEVSLRAVCEDC ENSRNOP00000006498/1-2529 QFLVTLTVSSSGRNSSQALTFLSTRPDLAFRFIHVSWVNFRDISVNWNEEVSLRAVCEDC ***: * *:* *: **:: ***. * .***:::. .*:* :***: .**:*:*:.* ENSCPOP00000012326/1-2471 GEMPGLTYSWELFLVNATEKSRVTAPFCSTTRLLGSAALKATQESPEPEL---------L XP_004840597.1/1-2786 GETLSLSYSWELFWVNATEKSSIE------------------------------------ ENSP00000289672/1-2849 SEIPNLSYSWDLFLVNATEKNRIEVPFCRVVGLLGSLGLGAISESSQLNLLPTEPGTADP ENSMUSP00000120803/1-2521 GDVPDLTYSWDLFLVNATEKSAVEVPFCSTVGLLGALALGTSLKSSKSDL------PSNL ENSRNOP00000006498/1-2529 GDVSDLTYSWDLFLVNATEKNAVEVPFCSTVGLLGASALGASLKSFESHQ------PSNV .: .*:***:** ******. : ENSCPOP00000012326/1-2471 GARPSQASLPDSLAAAQHRAVLSIPGSAAVGPTGDRDWIPAAGDAMALEDALES-APWGP XP_004840597.1/1-2786 --------------------------------ASGR-WIPAASDTTAPGEAVED-QPRGP ENSP00000289672/1-2849 DATTTPFSREPSPVTLGQPATSAPRGTPTEPMTGVY-WIPPAGDSAVLGEAPEE-GSLDL ENSMUSP00000120803/1-2521 RAPLTPHSPEPSPTPLGWTALSNLGSISAESTAGGH-HVPASGAVAGSGEPMEEYSSLS- ENSRNOP00000006498/1-2529 RASPTPHSLGPSPTPLGWTALSNLGSISAESPAGGH-HIPAAGPVAGSGEPMEDYGSLSP :. :*.:. :. *. . . ENSCPOP00000012326/1-2471 QPATK--------SPSVQSQPPPGSSPPLDDFEAFYSDIQEAEVAGGRRPGNSSPFPGSG XP_004840597.1/1-2786 EPVAQAEGAPPTMSPSSRSQPQPSSPPALDDFEDYYGNIQEAEPAGGRQPGHSTGVSSA- ENSP00000289672/1-2849 EPGPQSKGSL-MTGRSERSQPTHSPDPHLSDFEAYYSDIQEAIPSGGRQPAKDTSFPGSG ENSMUSP00000120803/1-2521 ---SLAEEAL-MTNSSEGSWPSPSSSTDFDDFEAYYSDIQEAVLSLGRQPGTSTNFQEAG ENSRNOP00000006498/1-2529 APSSLAEEAL-MMSDPEGSWPFPSSSTAFDDFEAYYSDIQEAVPSLGRQPGISANFQEAG . . . * * .. . :.*** :*.:**** : **:*. .: . : ENSCPOP00000012326/1-2471 PSTEMDTAQGSPGDGDSLLGPFFSVDRAPPVLDIDWPKAPVSHAVFQSYTAGGVSEPTMT XP_004840597.1/1-2786 -----DAAEGSPGEGDNLLDPFTSADRASPVLTIDWPKARLSRAVLRGYTEAGITKPTVT ENSP00000289672/1-2849 PS---LSAEESPGDGDNLVDPSLSAGRAEPVLMIDWPKALLGRAVFQGYSSSGITEQTVT ENSMUSP00000120803/1-2521 PS---LSAEESASYGDNLLGPFLHTGRAKPTLMIDWPKALVSQAAFHGYTTSGIMGPAVT ENSRNOP00000006498/1-2529 SS---LSAEESASYGDNLLGPFLHTGRAKPTLMIDWPKALVSRAVFHGYTTSGIMGPDVT :*: *.. **.*:.* ..** *.* ****** :.:*.::.*: .*: :* ENSCPOP00000012326/1-2471 IKPYSLSSGETYVLQASLAAGPSVWGRAQLYVPVRPVPQGVNCQLQPHHGLEALTVFSIF XP_004840597.1/1-2786 LKPYSLSSGETYVLQASVAAEPSELGRAQLYVRVPRVPRDAACQVQPQRGLEALTIFSVF ENSP00000289672/1-2849 IKPYSLSSGETYVLQVSVASKHGLLGKAQLYLTVNPAPRDMACQVQPHHGLEAHTVFSVF ENSMUSP00000120803/1-2521 IKPFSLSSGKTYVLQASVASKHVLLGKAQLYLTVNQAPQDMSCQVRPHHGMEAYTIFSVF ENSRNOP00000006498/1-2529 IKPFSLSSGEMYVLQASVASKHVLLGKAQLYLTVNQAPQDMSCQVRPHRGMEAHTIFSIF :**:*****: ****.*:*: *:****: * .*:. **::*::*:** *:**:* ENSCPOP00000012326/1-2471 CMSGAPDFHYEFSYRVGNAPRHTLYRGRDTQYYFALPAGDPLDNYRVMVTTEITDGQGSR XP_004840597.1/1-2786 CMSGTPDFHYEFSYWVGNASRHTLYRGRDTQYYFALPAGDPLDNYKVMVSTEITDGQGSR ENSP00000289672/1-2849 CMSGKPDFHYEFSYQIGNTSKHTLYHGRDTQYYFVLPAGEHLDNYKVMVSTEITDGKGSK ENSMUSP00000120803/1-2521 CMSGKPDFHYEFRYRIGNTSSHTLYRGQDTQHYFLLPAGDSSDNYKVIVSTEITDGHGSK ENSRNOP00000006498/1-2529 CMSGKPDFHYEFRYRIGNASSHTLYRGQDTQYYFLLPAGDSSDSYKVIVSTEVTDGQGSK **** ******* * :**:. ****:*:***:** ****: *.*:*:*:**:***:**: ENSCPOP00000012326/1-2471 IQPCSLAVTVMPHYHGNSCLNEDLYSSSLRNLSTLQLMGSDSESRNYVAMLTSILSRLAK XP_004840597.1/1-2786 IQPCSVAVTVLPRYYGNSCLSEDLYNSSLRNLSVLWLMGSDTESRNYIAMLTGILSRLAK ENSP00000289672/1-2849 VQPCTVVVTVLPRYHGNDCLGEDLYNSSLKNLSTLQLMGSYTEIRNYITVITRILSRLSK ENSMUSP00000120803/1-2521 VQPCTVAVTVLPRYHGNDCCDKELYNSTLESLSTLRLAGSYMETRNYITMITGILSRLYV ENSRNOP00000006498/1-2529 VQPCTVEVTVLPRYHGNDCHDKDLYNSTLENLSTLQLVGSYTEIRNYIAMITGILSRLYV :***:: ***:*:*:**.* .::**.*:*..**.* * ** * ***::::* ***** ENSCPOP00000012326/1-2471 EDT-STSCDWWSPMQDMLISAVCQSAVADQEEMIDSVLTLRNLISLPIKLRLPTATRILR XP_004840597.1/1-2786 ENT-STSCDQWSPLQDALISAVCTLAFADEEEMMDSVHTLRNLVNLPIKLGFLSAARILR ENSP00000289672/1-2849 EDK-TASCNQWSRIQDALISSVCRLAFVDQEEMIGSVLMLRDLVSFSNKLGFMSAVLILK ENSMUSP00000120803/1-2521 ESRNTSSCGQWSQIQDVLISSACKVPYTDQEGMMDSIHILRDLISFPNKLSLTSAMCIFK ENSRNOP00000006498/1-2529 ESRNTSSCGQWSQIQDVLIFSACKVPYTDQETMMDSIHILRDLISFPNKLSLMSAELIYK *. ::**. ** :** ** :.* . .*:* *:.*: **:*:.:. ** : :* * : ENSCPOP00000012326/1-2471 FTRMLL-QDPAQLTGRTVGDRGLGLELILLISGVLEASEPGKSRHQNYMREEGLKVISEV XP_004840597.1/1-2786 FAHTLLVQDQTHFSGKFVGAGGRRLELILLISGVWEASEHGTWRHEDYILEEGKRVISDM ENSP00000289672/1-2849 YTRALL--AQGQFSGPFVIDKGVRLELIGLISRVWEVSEQENSKEEVYRHEEGITVISDL ENSMUSP00000120803/1-2521 YTKMFL--AQGQFSRRLLVDKKLRVEFVLLISGVWEAAK-EDARDGDYLQEEGMKIISDM ENSRNOP00000006498/1-2529 YAQMFL--AQGQVSRRLLVDEKLRVEFILLISGVWEAAK-EDVRDGYYLQKEGMKIVSDM ::: :* :.: : :*:: *** * *.:: :. * :** ::*:: ENSCPOP00000012326/1-2471 LL----------LSLSAGQIEFRVLRHHDPRGSTQSLGPILVHLPGDLAG-LSPASKETQ XP_004840597.1/1-2786 LLAALPLSPGQQLSVSAGQMEFRVLLHRGLHCSVQSLGSVLVHLPRDLAG-LSPAAEETQ ENSP00000289672/1-2849 LLGCLSL-----NHVSTGQMEFRTLLHYNLQSSVQSLGSVQVHLPGDLAG-HSPAGAETQ ENSMUSP00000120803/1-2521 LL----------IHVSTGQMEFQTLLHRSPQSSIQNLGFVQVHFPSDLASLHSTTQEATQ ENSRNOP00000006498/1-2529 LL----------IHISTGQMEFQTLVHRSPQSSIQNLGFIRVHLPNDVAL-HSPTQEETQ ** :*:**:**:.* * . : * *.** : **:* *:* *.: ** ENSCPOP00000012326/1-2471 SPCYISQLMLFRKSPYPGGPAASQVGSVVDLTLYSCLSRSPIPRRRLETPVTVEFADEQ- XP_004840597.1/1-2786 APCYISQLTLFRRRLHPGGGAAGQVGGILGLSLYSCPSRSPIRRRQLRTPVTVEFGDEDS ENSP00000289672/1-2849 SPCYISQLILFKKNPYPGSQAPGQIGGVVGLNLYTCSSRRPINRQWLRKPVMVEFGEEDG ENSMUSP00000120803/1-2521 SSCYISQLMFFMKSPYLGGQVPGQVGGVMIPRLYSCESRRPILRGQLETPVTMEFGEEDY ENSRNOP00000006498/1-2529 SPCYISQLTFFMKSPYSGEQAPGQLGGVMSPWLYSCKSRRPILRGRLETPVTIEFGEEDH :.****** :* : : * ...*:*.:: **:* ** ** * *..** :**.:*: ENSCPOP00000012326/1-2471 -DHSTCEGPFVLHQDRVNVHRFAGLAQHPHEVLQIRIEFAEPETRAFPVLLLLSFSRRPS XP_004840597.1/1-2786 GDNETSEGSFVLLREQVHFHQFALLSQHPQELLQIHIEFAELETPAFPVLLLFSFSKKPS ENSP00000289672/1-2849 LDNRRNKTTFVLLRDKVNLHQFTELSENPQESLQIEIEFSKPVTRAFPVMLLVRFSEKPT ENSMUSP00000120803/1-2521 L-HKRNPAMFVLLRDEVNVHRFTGLSENSQESLQIHIKFSKPVTRPFPIILLVRFSEKAT ENSRNOP00000006498/1-2529 L-HKKNPAMFVLLRDEVNVHQFTGLSENSQESLQIHIEFSKPVIRAFPIILLVRFSEKAT : *** ::.*:.*:*: *:::.:* ***.*:*:: .**::**. **.:.: ENSCPOP00000012326/1-2471 PSDFLVQKTHSWDARSLRVYAPAAAGPGADVGYLSLLDADYDKRALNRHFMGAVNYTLRF XP_004840597.1/1-2786 PSDFLVQQTRFQDQQSVRIFAPTALGRAANVGYLSLLDAYYDRRAPSTFLAKAVSYTAHF ENSP00000289672/1-2849 PSDFLVKQIYFWDESIVQIYIPAASQKDASVGYLSLLDADYDRKPPNRYLAKAVNYTVHF ENSMUSP00000120803/1-2521 PSDFLVKRVYFWDEQTVQMYVPAAPWKGANVGYLSLLDADYDRKPPNKYLAGAVNYTVHF ENSRNOP00000006498/1-2529 PSDFLMKQVYFWDEQTVQMYVPAAPWRGANVGYLSLLDADYDRKPPNKYLAGAVNYTVHF *****::: * :::: *:* *.********* **::. . .: **.** :* ENSCPOP00000012326/1-2471 QWLRCLFWDQRDWQSGRSPPRAGTFPDRVNCSYDRFAPFSILRRPLNSSFEVNDVSQGQG XP_004840597.1/1-2786 QWIRCLFWERGEWKSGRFSPQPGTSPDKVNCSYDRLAPFSTLRRRLNASFEASDISEVQS ENSP00000289672/1-2849 QWIRCLFWDKREWKSERFSPQPGTSPEKVNCSYHRLAAFALLRRKLKASFEVSDISKLQS ENSMUSP00000120803/1-2521 QWIQCVFWDKTEWRSEGPYPQPGSSPEKVNCSYHHLAPVSVLRRKLNATLEVSSISEFQS ENSRNOP00000006498/1-2529 QWIQCVFWDKTEWRSEGPCPQPGTSPEKVNCSYHRLAPFSVLRRKLNATFQVSSVSEFQS **::*:**:: :*:* *:.*: *::*****.::*..: *** *:::::...:*: *. ENSCPOP00000012326/1-2471 HPGNLLPGMCVVVLMVLCGLTVVKSRLAALRSERKADCIFLQAAMPPGHLPYAVVVDTSF XP_004840597.1/1-2786 PPQNLLPSVCMGVITVLYGLLVMKSNLVDRRKEKGPGYIFLQEAAPPGHQLYAVVVDTGF ENSP00000289672/1-2849 HPENLLPSIFIMGSVILYGFLVAKSRQVDHHEKKKAGYIFLQEASLPGHQLYAVVIDTGF ENSMUSP00000120803/1-2521 HPHNLLPGIFSAFLLVLYGILVSKSRYVDCHEKKNPGFIFLEEDTLPGYQLYAVVIDTGF ENSRNOP00000006498/1-2529 HPHNLLPSIFSVFFLVLYGFLMSKSSCVDCHKKKDPGCIFLEEEALLGHQLYAVVIDTGF * ****.: :* *: : ** . :.:: .. ***: *: ****:**.* ENSCPOP00000012326/1-2471 WAPVQFTSRVFIVLCGENGLSETRELCCPEKTLFKRNSRHTFILSAPAYLGPLRRVRLWH XP_004840597.1/1-2786 WSPARFTSRVFIVLFGESGLSETRELCCPERTLFERNSRHTFILSAPAQLGPLWKVRVWH ENSP00000289672/1-2849 RAPARLTSKVYIVLCGDNGLSETKELSCPEKPLFERNSRHTFILSAPAQLGLLRKIRLWH ENSMUSP00000120803/1-2521 RSPVRFTSKVFIVLCGENGCSETKELCCPEKPLFGRNSRHTFILSIPNQLGPLQKIRLWH ENSRNOP00000006498/1-2529 RSPARFTSKVFIVLCGENGHSETKELCCPEKPLFGRNSRHTFILSTPHQLGPLQKIRLWH :*.::**:*:*** *:.* ***:**.***:.** ********** * ** * ::*:** ENSCPOP00000012326/1-2471 DSSGPAPSWLLDSVIVKELHSGQAWLFPARCWLAAGRGDGRVERELPCLRQGLGFRKLFC XP_004840597.1/1-2786 DSSGPAPRWLLSCVMVKELQSGRAWFFPARCWLAAGQGDGRVERELPCLRQGLGFWKLFC ENSP00000289672/1-2849 DSRGPSPGWFISHVMVKELHTGQGWFFPAQCWLSAGRHDGRVERELTCLQGGLGFRKLFY ENSMUSP00000120803/1-2521 DSSGSSPCWFISHVMVKELCSGQAWFFSAQCWLAVSKLGGHVLREFFCLSHGLGFWKLFY ENSRNOP00000006498/1-2529 DSSGLSPSWFISHVMVKELCSGQAWFFSAQCWLAVSKRGGQVLGEFFCLSHGLSFWKLFY ** * :* *::. *:**** :*:.*:*.*:***:..: .*:* *: ** **.* *** ENSCPOP00000012326/1-2471 TRFSESLESSHTWLSLCSPPSSRGPPRMQHLAVCFCLLCTHMGLTALATAGGHGQLLLDI XP_004840597.1/1-2786 AKLTEALEGCHVWLSLCGPPRSHGPSRTQRLAVSLCLLCTHACLTALATAGGRDQLLPDV ENSP00000289672/1-2849 CKFTEYLEDFHVWLSVYSRPSSSRYLHTPRLTVSFSLLCVYACLTALVAAGGQEQPHLDV ENSMUSP00000120803/1-2521 SKFTEYLEDFHIWLSLYSQPPSRSYLHTQRLAVSFCLLCVYSCLTALVTVRDHQQRPLDV ENSRNOP00000006498/1-2529 SKFTEYLEDFHIWFSLYSQPPSSNYLHTQRLAVSFCLLSVYSCLTALVTVGGHEQRPLGV :::* **. * *:*: . * * : :*:*.:.**..: ****.:. .: * .: ENSCPOP00000012326/1-2471 GPTDLTLATLGLGLLCALTASCVAQLLLLL-FRYGQGAEEHP-AEPQGPPRMRTQMEAPP XP_004840597.1/1-2786 -----VLGDLGLGLLCALAASPVAQLLPLL-FRCSQEAKGLPRAEPQGA-RTRTQLEVPQ ENSP00000289672/1-2849 SP---TLGSFRVGLLCTLLASPGAQLLSLL-FRLSKEAPGSARVEPHSPLRGGAQTEAPH ENSMUSP00000120803/1-2521 GPTAITLEPFCMALLCTLLACPVAQLLSLL-FRCSKEARGDMQASTQWPLR-GVKTETPQ ENSRNOP00000006498/1-2529 GPTAITLDSFSLALLCTILACPPAQLLSLLNLFASQEARGHLRTSRQWPLR-GVKTEVPQ .* : :.***:: *. **** ** : .: * .. : . * .: *.* ENSCPOP00000012326/1-2471 GNVWKGR---SSQPSQDPRGPLSPWPCEALYLGAGSMSAPRMCTVLIPREGCRPSRHPPR XP_004840597.1/1-2786 GE---------------------------------------------------------- ENSP00000289672/1-2849 GPNSWGRIPDAQEPRKQPASAILSGSGRAQRKAASD-NGTACPAPKLQVHGADHSRTS-- ENSMUSP00000120803/1-2521 GHDSSGR-PDSRQPSPHPTSDLLPWNDQAWRIAASS-SAVVCSP--FPMEACSHKHHD-- ENSRNOP00000006498/1-2529 GPDPGGK-PDSRQPSPHPISDLLPGTDQAWRMTASN-SGIVHSS--FPLEACRDKHLA-- * ENSCPOP00000012326/1-2471 RPRFLNTRPSCCPA---APSHSREGLVALGHRARPPWPRAAAWTICGLVSLASGLGTGFL XP_004840597.1/1-2786 -----------------APSDGHEGLEPQGPSACQLPPNTAAWTICGMVTLACGLGTGFL ENSP00000289672/1-2849 ----LMGKSHCCPPHTQAPSSGLEGLMPQWSRALQPWWSSAVWAICGTASLACSLGTGFL ENSMUSP00000120803/1-2521 ----LREKSHYSPPSSQAPGSGFEELGSQKSRVCLLWSSSVAWAISGSASLACGLGTGFL ENSRNOP00000006498/1-2529 ----LRERSHCSPPSSQAPSSGFEELRPQQSRVCLLWSSSVAWAISGTASLACGLGTGFL **. . * * . . :..*:*.* .:**..****** ENSCPOP00000012326/1-2471 GYRFLPVQNMGWLLLLSLSVVFCAFVTQPLLICCAALCFSWARRGDSQCFAASVHEATRH XP_004840597.1/1-2786 GYRFLPAQCAQWLLLLSLSVVCCAFITQPLLICCAALGFAWKRRADSQCFAESLREATEH ENSP00000289672/1-2849 AYRFGQEQCVQWLHLLSLSVVCCIFITQPLMVCLMALGFAWKRRADNHFFTESLCEATRD ENSMUSP00000120803/1-2521 GYWFVPAQCMWWLYLLLLSLVCCAFITQPLMICLAALVFAWKRKHDSKFFTESLQDATKG ENSRNOP00000006498/1-2529 GYKFVPAQCVWWLHLLLLSLVCCALITQPLMICLAASAFAWKRKHDSEFFTESLQDATKG .* * * ** ** **:* * ::****::* * *:* *: *.. *: *: :**. ENSCPOP00000012326/1-2471 LGSGQEEYLGQGPGPRILASPGPCATDCTVGLEEVLAARQRERCLRRAQPPHRAQLRAVR XP_004840597.1/1-2786 LGSGLEER----PGPHTRASPGP-----TAGLAEVLAARQRERHLRRARPPSRAQLRVTR ENSP00000289672/1-2849 LDSELAER----SWTRLPFSSSCSIPDCAGEVEKVLAARQQARHLRWAHPPSKAQLRGTR ENSMUSP00000120803/1-2521 LDLELEEH----SRTRVPLSPISYSPDTAEEAERVLATRQRERHLRWAQTPSKAKLRVTG ENSRNOP00000006498/1-2529 LDLELEER----SRTHIPLSPVSYSPDSAEEAERVLAARQRERHLRWAQTPSGPKFRVMR *. * . .: *. : .***:**: * ** *:.* .::* ENSCPOP00000012326/1-2471 ERTRREWHAHLALRDIAVHVLSLLLLLWLTYVTFS-EDAHSLSRALRKELQRSCVNVGGE XP_004840597.1/1-2786 ERTKRARRAQAALRGLAMHGLTLLLLTWLTHGAFSTAAEHALNRAIRKALASSARCSPG- ENSP00000289672/1-2849 QRMRRESRTRAALRDISMDILMLLLLLCVIYGRFS-QDEYSLNQAIRKEFTRNARNCLGG ENSMUSP00000120803/1-2521 ERLRRESIMQAALRDMTTHSIMLLLLLFIAYGRFC-PGEISLNHAIRKAFTRKANHSLGD ENSRNOP00000006498/1-2529 ERLRRERLMQAALRDVTMHSVMLLLLLFIAYGRFC-PGEYSLNQAIRRAFTRNAHHSLGD :* :* : ***.:: . : **** : : *. :*.:*:*: : .. * ENSCPOP00000012326/1-2471 CSSVGAGDGGSRRPSSLRDGLHAGGPSVARAAGAQPGALEGQYYLLGALVTTQLTSTPGS XP_004840597.1/1-2786 -----AGDRSDCRLSSLLDALLTGGPSAAGAPGAQPGALGGKCYLLGASVIQQPQDPPSS ENSP00000289672/1-2849 LRN--IADWWDWSLTTLLDGLYPGGTPSARVPGAQPGALGGKCYLIGSSVIRQLKVFPRH ENSMUSP00000120803/1-2521 LSS--TEDWWDWTLSTLLDELYPERTS-ARAWGAQPGALGGQCHLIGPPVVKLLKISAGT ENSRNOP00000006498/1-2529 LSS--TEDWWDWTLSTLLDGLHPERMP-ATAWGSQPGALGGQCHLIGPSVIKQLKVSAGT * . ::* * * . . * . *:***** *: :*:*. * . ENSCPOP00000012326/1-2471 LHEPLWPSPTLPEDSRPPWSPKA--------KGFEDRNVTHSGPRSCRVRKEANRPGLGQ XP_004840597.1/1-2786 LPKPPGPSPAPLEDSLPLWSPDP--------RGLEDQNLTHGGPGHCLLSP-------GR ENSP00000289672/1-2849 LCKPPRPFSALIEDSIPTCSPEVGGPENPYLIDPENQNVTLNGPGGCGTREDCVL-SLGR ENSMUSP00000120803/1-2521 ACTPPRPFSELVEDVLPMHSND---------LDLENQNVSPGGPETCGVKKESYMHSLGK ENSRNOP00000006498/1-2529 ACVAPKPFSELVEDVLPMHSHA---------LDLENRNVTPDDPKTCGVKKESYTHSLGR . * . ** * * . *::*:: ..* * *: ENSCPOP00000012326/1-2471 IKLEAYMVLTALRASGWLDSSTRAETVHLALYHPATQLFTSITLSANTPPVGRPVPSAWV XP_004840597.1/1-2786 TRLEAQALLSTLRARGWAAASMR-----LVLYHPPSQLFTSIALRAQ------PLPAAWV ENSP00000289672/1-2849 TRTEAHTALSRLRASMWIDRSTRAVSVHFTLYNPPTQLFTSVSLRVEILPTGSLVPSSLV ENSMUSP00000120803/1-2521 TRHEAHAALTALRASKWIDHSTRAMSVHFTLYNPPTQLFTSVILGTECLPSGGLVPSFLV ENSRNOP00000006498/1-2529 TRHEAHAALTALRASRWIDHSTRAVSVHFTLYNPPTRLFTSVTLGAEFLSTRGLVSSSLI : ** *: *** * * * :.**:*.::****: * .: :.: : ENSCPOP00000012326/1-2471 ESFRVFRGGSTTWYHRTIPE-----------------LAFLVLSLAHLSLQLYEMAEGGA XP_004840597.1/1-2786 ESFRVFWGSSS--YHHVLPEPEAGLKSSLSEIPCPLQLAFLVLSLARLSLHLYSMAEVGA ENSP00000289672/1-2849 ESFSIFRSDSALQYHLMLPQ-----------------LVFLALSLIHLCVQLYRMMDKGV ENSMUSP00000120803/1-2521 ESFRIFYSDSALKYLLMLSE-----------------LLFLVLNVIHLCFQLWGMTTKGI ENSRNOP00000006498/1-2529 ESFSIFYRDSALQCLLMLSE-----------------LLFLVLNMIHLCFQLWEMATKGI *** :* .*: :.: * **.*.: :*..:*: * * ENSCPOP00000012326/1-2471 LCYWRKPRNWLE------------------LPTVSMALAYYVATGILAGLAADLADQIRQ XP_004840597.1/1-2786 LSYWRRPRNWLEAGTAASRPLPSRLSFLSQLPALGAALAYYAACGLLSLHAGDVAQQLRG ENSP00000289672/1-2849 LSYWRKPRNWLE------------------LSVVGVSLTYYAVSGHLVTLAGDVTNQFHR ENSMUSP00000120803/1-2521 LSYWRKPRHWLE------------------LSMVGVAIAYYAASGHLTTLAVNITDQFHK ENSRNOP00000006498/1-2529 LSYWRKPRQWLE------------------LSMVGVALAYCAASGHLTTLAENITDQFHK *.***:**:*** *. :. :::* .. * * * ::::*:: ENSCPOP00000012326/1-2471 GPCRAALDLRPMALWNWRARCLQGLLLFLWMLKCISLPGLLDVAMSCC-------PRVW- XP_004840597.1/1-2786 GPCQGPLDLSLMALWSQRARWLRGLLLFLWTLRCISLPGLLHVASSCC-------LRMRM ENSP00000289672/1-2849 GLCRAFMDLTLMASWNQRARWLRGILLFLFTLKCVYLPGIQNTMASCSSMMRHSLPSIFV ENSMUSP00000120803/1-2521 GLYQRLVDIGLMVSWHQRARCLQGILLFLWMLKYVHLLSSLSTMTPFSAVTCFPLFRVL- ENSRNOP00000006498/1-2529 GLYQRFVDISLMVSWNQRARCLQGILLFLWMLKCVHLFSSLSTMAPFSAVTCSLLFRVLM * : :*: *. * *** *:*:****: *: : * . . . . : ENSCPOP00000012326/1-2471 --LVGVLVLAAHAHLHHL-LSAAW----ALPPSTFARLDTRL---LLPLGFPRRSQEDSV XP_004840597.1/1-2786 RGLVSGVSTAVVRILRWLPFQPVWRAGRAASPGATP--SSIPVTSSMVVVFPHRSQGHLV ENSP00000289672/1-2849 AGLVGALMLAALSHLHRF-LLSMW----VLPPGTFT--DAFP---GLLFHFPRRSQKDCL ENSMUSP00000120803/1-2521 --LVGALLLAAHYHSRWF-LLFTG----TLSHGTSA--EAFP---GLLLQFPGRSKKDSW ENSRNOP00000006498/1-2529 PTLVGALLLAAHSHLRWF-LLYTS----TLSRGTSA--EAFP---GLLLQFPGRSQKDSQ **. : *. : : : . . .: . .: : . ** **: . ENSCPOP00000012326/1-2471 ----------PALSTSHWPA---------VAWYLGALAI-VMATLCLGTLRVSLLTCFQK XP_004840597.1/1-2786 NRGRDWTGGGPGAGRPHPPAPPSERRLDTASPHLRTLRIPAAAAAGVAREKPGRLVPEPP ENSP00000289672/1-2849 ----------LGLSKSDQRA---------MACYFGILLI-VSATLCFGMLRGFLMTLPQK ENSMUSP00000120803/1-2521 ----------HNCLKSDHGV---------MRCYYGTLFL-LLATLGFRMLRATFLTVFQN ENSRNOP00000006498/1-2529 ----------HNHLESDHRA---------VNCYYGTLFL-LLATLGFRMLRATSLTLFQD .. . : * : *: . : :. ENSCPOP00000012326/1-2471 RKPFHCKSPVRLEEVAALVWWKTLALLGL-------EEPARAE----AGVALEQNHYLDE XP_004840597.1/1-2786 HVPPASRGWELGPGPAHFSLSKVLQTPKALCASDNEETKTRPEMRFLIHFCSPQSHCLEE ENSP00000289672/1-2849 RKSFQSKSFVRLKDVTAYMWEKVLTFLRL-------ETPKLEE----AEMVENHNYYLDE ENSMUSP00000120803/1-2521 RKSSHRKPLVTLKDIAVYTWHKVLTLLGL-------ETTLE-E----TEVATDHIYYLDE ENSRNOP00000006498/1-2529 RKSFHRKSLVTLKDVAVSMWHRLLTFLRL-------ETTTSGE----TEVTTDHIYYLDE : . : : : * * * . : : *:* ENSCPOP00000012326/1-2471 FSGLLDELLLKINALSDGLEAPVAEEP--RAAGPRAEVPPTMPISGYPSGRI------SG XP_004840597.1/1-2786 FSSLLDELLVKVEALSHGLELPALEEP------RPADDSPAVSIPAHRAPGAPNARIEAA ENSP00000289672/1-2849 FANLLDELLMKINGLSDSLQLPLLEKTSNNTGEARTEESPLVDISSYQA---------AE ENSMUSP00000120803/1-2521 FSSLLDELLMKIDGLSDSLELSILENQWKRALESRAGDSPPVGSSEYQATGV------SG ENSRNOP00000006498/1-2529 FSSLLDELLMKIDGLSDSLELSILEKQWRRTVESRTGDSPSVGILEYQAAGC------ST *:.******:*::.**..*: . *: : .* : : : : ENSCPOP00000012326/1-2471 PAVTKEQ----------- XP_004840597.1/1-2786 PLAESNRDLFCPEPFYTI ENSP00000289672/1-2849 PADIKDF----------- ENSMUSP00000120803/1-2521 PLAAESE----------- ENSRNOP00000006498/1-2529 PLFLRSE----------- * .