CLUSTAL W(1.81) multiple sequence alignment ENSMUSP00000001202/1-900 MEPRLPIGAQPLA---MVAGLEMKGPLREPCVLTLARRNGQYELIIQLHGKEQHVQDIIP ENSRNOP00000005267/1-899 MEPRLPIGAQPLA---MVAGLEMKGPLREPCVLTLARRNGQYELIIQLHGKEQHVQDIIP ENSP00000360154/1-901 MEPPLPVGAQPLA---TVEGMEMKGPLREPCALTLAQRNGQYELIIQLHEKEQHVQDIIP ENSCPOP00000012251/1-888 MEPLLPIGAQPLA---TIEGLEMKGPLREPCALTLAQRNGQYEFIIQLQEKE-HVQD-IP XP_004860090.1/1-896 MEPRLPVGAQPLARPHTVEGLEMKGPLREPCTLTLAQRNGQYELIIQLQEKERHSQDIIP *** **:****** : *:**********.****:******:****: ** * ** ** ENSMUSP00000001202/1-900 INSHFRCVQEAEETLLIDIASNSGCKIRVQGDWTRERHFEIPDEERCLKFLSEVLEAQEA ENSRNOP00000005267/1-899 INSHFRCVQEAEETLLIDIASNSGCKIRVQGDWTRERHFEIPDEERCLKFLSEVLAAQEA ENSP00000360154/1-901 INSHFRCVQEAEETLLIDIASNSGCKIRVQGDWIRERRFEIPDEEHCLKFLSAVLAAQKA ENSCPOP00000012251/1-888 INSHFRCVQEAEETLLIDIASNSGCKIRVQGDWTRERRFEIPDEEHCLKFLSEVLAAQEA XP_004860090.1/1-896 INSHFRCVQEAEETLLIDIASNSGCKIRVQGDWSRERRFEIPDEEHSVKFLSEVLAAQEA ********************************* ***:*******:.:**** ** **:* ENSMUSP00000001202/1-900 QSQLLVPEQKDSSSWYQKLDTMDKPA-YSGLLGFEDNFSSLDLDKKMNTQNPRSGSHREP ENSRNOP00000005267/1-899 QSQLLVPEQKDSSNWYQKLDTKDKPA-YSGLLGFEDNFSSMNLDKKMNTQNPPTGIHREP ENSP00000360154/1-901 QSQLLVPEQKDSSSWYQKLDTKDKPSVFSGLLGFEDNFSSMNLDKKINSQNQPTGIHREP ENSCPOP00000012251/1-888 QSQLLVPEQKDSSSWYQKLDTKDKPSIFPGLLGFEDNFSSMNLDKKMNSQNQSTGIHRD- XP_004860090.1/1-896 QSQLLVPEQKDSSSWYQKLDTKDKPSVFSGLLGFEDNFSSMNLDKKINSQNQPTGIHREP *************.******* ***: :.***********::****:*:** :* **: ENSMUSP00000001202/1-900 PPPPSSSTRMLSREKEASNKEQPKVTNTMRKLFVPNTQTGQREGLIKHILTKREKEYVNI ENSRNOP00000005267/1-899 PPPP-SSNRMLPREKEALNKEQPKVTNTMRKLFAPNSQSGQREGLIKHILAKREKEYVNI ENSP00000360154/1-901 PPPPFSVNKMLPREKEASNKEQPKVTNTMRKLFVPNTQSGQREGLIKHILAKREKEYVNI ENSCPOP00000012251/1-888 ------VNRMLPREKEASNKELPKVTNTMRKLFVPNTQSGTREGLIKHILAKREKEYVNI XP_004860090.1/1-896 PPPPPSVNRMLPREKETSNKEQPKVTNTMRKLFVPNTQSGTREGLIKHILAKREKEYVNI .:**.****: *** ***********.**:*:* *********:********* ENSMUSP00000001202/1-900 QSFRFFVGTWNVNGQSPDSSLEPWLDCDPNPPDIYCIGFQELDLSTEAFFYFESVKEQEW ENSRNOP00000005267/1-899 QSFRFFVGTWNVNGQSPDSSLEPWLNCDPNPPDIYCIGFQELDLSTEAFFYFESVKEQEW ENSP00000360154/1-901 QTFRFFVGTWNVNGQSPDSGLEPWLNCDPNPPDIYCIGFQELDLSTEAFFYFESVKEQEW ENSCPOP00000012251/1-888 QTFKFFVGTWNVNGQSPDSGLEPWLNCDPNPPDIYCIGFQELDLSTEAFFYFESVKEQEW XP_004860090.1/1-896 QNFKFFVGTWNVNGQSPDSGLEPWLNCDPNPPDIYCIGFQELDLSTEAFFYFESVKEQEW *.*:***************.*****:********************************** ENSMUSP00000001202/1-900 SLAVERGLPSKAKYRKVQLVRLVGMMLLIFARKDQCQYIRDVATETTGTGIMGKMGNKGG ENSRNOP00000005267/1-899 AMAVERGLPSKAKYKKVQLVRLVGMMLLVFAKKDQCQYIRDIATETVGTGIMGKMGNKGG ENSP00000360154/1-901 SMAVERGLHSKAKYKKVQLVRLVGMMLLIFARKDQCRYIRDIATETVGTGIMGKMGNKGG ENSCPOP00000012251/1-888 CMAVERGLHSKAKYKKVQLVRLVGMMLLIFARKDQYRYIRDVATETVGTGIMGKMGNKGG XP_004860090.1/1-896 SMAVERGLHSKAKYKKVQLVRLVGMMLLIFARKDQYRYIRDVATETVGTGIMGKMGNKGG .:****** *****:*************:**:*** :****:****.************* ENSMUSP00000001202/1-900 VAVRFVFHNTTFCIVNSHLAAHVEEFERRNQDYKDICARMTFSVPNQTVPQVNIMKHDVV ENSRNOP00000005267/1-899 VAMRFVFHNTTFCIVNSHLAAHVEEFERRNQDYKDICARMSFSVPNQTLPQVNIMKHDVV ENSP00000360154/1-901 VAVRFVFHNTTFCIVNSHLAAHVEDFERRNQDYKDICARMSFVVPNQTLPQLNIMKHEVV ENSCPOP00000012251/1-888 VAVRFVFHNTTFCIVNSHLAAHVEDFERRNQDYKDICARMSFVVPSQTLPQLNIMKHDVV XP_004860090.1/1-896 VAVRFVFHNTTFCIVNSHLAAHVEDFERRNQDYKDICARMSFVVPSQTLPQLNIMKHDVV **:*********************:***************:* **.**:**:*****:** ENSMUSP00000001202/1-900 IWLGDLNYRLCMPDASEVKSLINKNELHKLLKFDQLNIQRTQKKAFADFNEGEINFVPTY ENSRNOP00000005267/1-899 IWLGDLNYRLCMPDANEVKSLINKNELQKLLKFDQLNIQRTQKKAFVDFNEGEIKFIPTY ENSP00000360154/1-901 IWLGDLNYRLCMPDANEVKSLINKKDLQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIPTY ENSCPOP00000012251/1-888 IWLGDLNYRLCMPDANEVKSLINKNDLQRLLKFDQLNIQRT----FIDFNEGEIKFIPTY XP_004860090.1/1-896 IWLGDLNYRLCMPDANEVKSLINKNDLQRLLKFDQLNIQRTQKKAFVDFNEGEIKFIPTY ***************.********::*::************ * *******:*:*** ENSMUSP00000001202/1-900 KYDSKTDRWDSSGKCRVPAWCDRILWRGINVNQLHYRSHMELKTSDHKPVSALFHIGVKV ENSRNOP00000005267/1-899 KYDSKTDRWDSSGKCRVPAWCDRILWRGINVNQLHYRSHMELKTSDHKPVSALFHIGVKV ENSP00000360154/1-901 KYDSKTDRWDSSGKCRVPAWCDRILWRGTNVNQLNYRSHMELKTSDHKPVSALFHIGVKV ENSCPOP00000012251/1-888 KYDSKTDRWDSSGKCRIPAWCDRILWRGTNVNQLNYRSHMELKTSDHKPVSALFHIGVKV XP_004860090.1/1-896 KYDSKTDRWDSSGKCRVPAWCDRILWRGTNVDQLHYRSHMELKTSDHKPVSGLFHIGVKV ****************:*********** **:**:****************.******** ENSMUSP00000001202/1-900 VDERRYRKVFEDIVRIMDRMENDFLPSLELSRREFFFENVKFRQLQKEKFQISNNGQVPC ENSRNOP00000005267/1-899 VDERRYRKVFEDIVRIMDRMENDFLPSLDLSRREFMFENVKFRQLQKEKFQISNNGQVPC ENSP00000360154/1-901 VDERRYRKVFEDSVRIMDRMENDFLPSLELSRREFVFENVKFRQLQKEKFQISNNGQVPC ENSCPOP00000012251/1-888 VDERRYRKVFEDIVRIMDRMENDFLPSLELSRREFVFENVKFRQLQKEKFQISNNGQVTC XP_004860090.1/1-896 VDERRYRKVFEDIVRIMDRMENDFLPSLELSRREFVFENVKFRQLQKEKFQISNNGQVPC ************ ***************:******.**********************.* ENSMUSP00000001202/1-900 HFSFIPKLNDSQYCKPWLRAEPFEGYLEPNETLDISLDVYVSKDSVTILNSGEDKIEDIL ENSRNOP00000005267/1-899 HFSFIPKLNDTQYCKPWLRAEPFEGYLEPNETIDISLDVYVSKDSVTILNSGEDKIEDIL ENSP00000360154/1-901 HFSFIPKLNDSQYCKPWLRAEPFEGYLEPNETVDISLDVYVSKDSVTILNSGEDKIEDIL ENSCPOP00000012251/1-888 HFSFIPKLNDSQYCKPWLRAEPFEGYLEPNETVDISLDVYVSKDSVTILNSGEDKIEDIL XP_004860090.1/1-896 HFSFIPKLNDSQYCKPWLRAEPFEGYLEPNETVDISLDVYVSKDSVTILNSGEDKIEDIL **********:*********************:*************************** ENSMUSP00000001202/1-900 VLHLDRGKDYFLTIGGNYLPSCFGTSLEALCRMKRPIREVPVTKLIDLEEDSYLEKEKSL ENSRNOP00000005267/1-899 VLHLDRGKDYFLTISGNYLPSCFGTSLEALCRMKRPIREVPVTKLIDLEEDSFLEKEKSL ENSP00000360154/1-901 VLHLDRGKDYFLTISGNYLPSCFGTSLEALCRMKRPIREVPVTKLIDLEEDSFLEKEKSL ENSCPOP00000012251/1-888 VLHLDRGKDYFLTISGNYLPSCFGTSLEALCRMKRPIREVPVTKLIDLEEDSFLEKEKSV XP_004860090.1/1-896 VLHLDRGKDYFLTISGNYLPSCFGTSLEALCRMKRPIREVPVTKLIDLEN--------SL **************.**********************************: *: ENSMUSP00000001202/1-900 LQMVPLDEGTSERPLQVPKEIWLLVDHLFKYACHQEDLFQTPGMQEELQQIIDCLDTSIP ENSRNOP00000005267/1-899 LQMVPLDEGTSERPLQVPKEIWLLVDHLFKYACHQEDLFQTPGMQEELQQIIDCLDTSIP ENSP00000360154/1-901 LQMVPLDEGASERPLQVPKEIWLLVDHLFKYACHQEDLFQTPGMQEELQQIIDCLDTSIP ENSCPOP00000012251/1-888 LQMVPLDEGASERPLQVPKEIWLLVDHLFKYACHQEDLFQTPGMQEELQQIIDCLDTSIP XP_004860090.1/1-896 LQMVPLDEGASERPLQVPKEIWLLVDHLFRYACHQEDLFQTPGMQEELQQIIDCLDTSIP *********:*******************:****************************** ENSMUSP00000001202/1-900 ETIPGNNHSVAEALLIFLEALPEPVICYELYQRCLDSAHDPRICKQVISQLPRCHRNVFR ENSRNOP00000005267/1-899 ETIPGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAHDPRICKQVISQLPRCHRNVFR ENSP00000360154/1-901 ETIPGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQVISQLPRCHRNVFR ENSCPOP00000012251/1-888 ETIPGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAHDPRICRQIISQLPRCHRNVFR XP_004860090.1/1-896 ETIPGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAHDPRICRQVISQLPRCHRNVFR *****.********************************:*****:*:************* ENSMUSP00000001202/1-900 YLMAFLRELLKFSDYNNINTNMIATLFSSLLLRPPPNLMTRQTPNDRQHAIQFLLVFLLG ENSRNOP00000005267/1-899 YLMAFLRELLKFSDYNNVSTNMIATLFTSLLLRPPPNLMARQTPSDRQRAIQFLLVFLLG ENSP00000360154/1-901 YLMAFLRELLKFSEYNSVNANMIATLFTSLLLRPPPNLMARQTPSDRQRAIQFLLGFLLG ENSCPOP00000012251/1-888 YLMAFLRELLKFSEYNNVSANMIATLFTSLLLRPPPNLMARPTSSDRQRAIQFLLGFLLG XP_004860090.1/1-896 YLMAFLRELLKCSEYNNVSANMIATLFTSLLLRPPPNLMARQTSSDRQRAIQFLLGFLLG *********** *:**.:.:*******:***********:* *..***:****** **** ENSMUSP00000001202/1-900 NEED ENSRNOP00000005267/1-899 SEED ENSP00000360154/1-901 SEED ENSCPOP00000012251/1-888 SDED XP_004860090.1/1-896 SDED .:**