CLUSTAL W(1.81) multiple sequence alignment ENSMUSP00000031727/1-1044 MAAETLNFGPEWLRALSSGGSVASPPPSPAMPKYKLADYRYGREEMLALYVKENKVPEEL ENSRNOP00000001912/1-1042 MAAETLNFGPEWLRALSSGGSVASPPPSPAMPKYKLADYRYGREEMLALYVKENKVPEEL ENSP00000275732/1-1035 MAAETLNFGPEWLRALSGGGSVASPPPSPAMPKYKLADYRYGREEMLALYVKENKVPEEL ENSCPOP00000012247/1-1015 MAAETLNFGPEWLRALSSGGSVASPPPSPAMPKYKLADYRYGREEMLALYVKEDKVPEEL XP_004840233.1/1-1035 MAAETLNFGPEWLRALSSGGSVASPPPSPAMPKYKLADYRYGREEMLALYIKEDKVPEEL *****************.********************************:**:****** ENSMUSP00000031727/1-1044 QDKEFAAVLQEEPLQPLALEPLTEEEQRNFSLSVNSVAVLRLMGKGAGPPLPATSRGRGS ENSRNOP00000001912/1-1042 QDKEFAAVLQEEPLQPLALEPLTEDEQRNFSLSVNSVAVLRLMGKGAGPPLAATSRGRGS ENSP00000275732/1-1035 QDKEFAAVLQDEPLQPLALEPLTEEEQRNFSLSVNSVAVLRLMGKGAGPPLAGTSRGRGS ENSCPOP00000012247/1-1015 QDKEFAAVLQEEPLQPLALEPLTEEEQRNFSLSVNSVAVLRLMGKGAAPPLTGTSRGRGS XP_004840233.1/1-1035 QDKEFAAVLQEEPLQPLALEPLTEEEQRNFSLSVNSVAVLRLMGKGAAPPLAGTSRGRGS **********:*************:**********************.***..******* ENSMUSP00000031727/1-1044 TRSRGRGRGDSCFYQRSIEEGDGAFGRNPREIQRSQSWDDRGERRFEKPARRDG--VRSG ENSRNOP00000001912/1-1042 TRSRGRGRGDSCFYQRSIEEGDGAFGRNPREIQRSQSWDDRGERRFEKSARRDG--VRSG ENSP00000275732/1-1035 TRSRGRGRGDSCFYQRSIEEGDGAFGRSPREIQRSQSWDDRGERRFEKSARRDG--ARCG ENSCPOP00000012247/1-1015 TRSRGRGRGDSCFYQRSIEEGDGAFGRNPREIQRSQSWDDRGDRRFEKSARRDGGPARSG XP_004840233.1/1-1035 TRSRGRGRGDSCFYQRSIEEGDGAFGRNPREIQRSQSWDDRGERRFEKPARRDG--ARSG ***************************.**************:*****.***** .*.* ENSMUSP00000031727/1-1044 FEEGGAGPRKEHARSDSENWRSLREEQ--EDDGSWRLGAGPRRDGDRWRSTSPDGGPRSA ENSRNOP00000001912/1-1042 FEEGGAGPRKEHARSDSENWRSLREEQ--EDDSSWRLGAGPRRDGDRWRSTSPDGGPRSA ENSP00000275732/1-1035 FEEGGAGPRKEHARSDSENWRSLREEQEEEEEGSWRLGAGPRRDGDRWRSASPDGGPRSA ENSCPOP00000012247/1-1015 FEESGAGPRKEHARSDSENWRSLREEQEEEEEGSWRLGAGPRRDGDRWRSASPDGGPRSA XP_004840233.1/1-1035 FEEGGAGPRKEHTRSDSENWRSLREEQEEEEEGSWRLGAGPRRDGDRWRSTSPDGGPRSA ***.********:************** *::.*****************:********* ENSMUSP00000031727/1-1044 GWREHGERRRKFDFDLRGERGGCGEEDGRVGGGNSHLRRCRGLDGFEDDKDGLPEWCLED ENSRNOP00000001912/1-1042 GWREHGERRRKFDFDLRGERGGCGEEDGRVGGGNSHLRRCRGLDGFEDDKDGLPEWCLDD ENSP00000275732/1-1035 GWREHGERRRKFEFDLRGDRGGCGEEEGRGGGGSSHLRRCRAPEGFEEDKDGLPEWCLDD ENSCPOP00000012247/1-1015 GWREHGERRRKFEFDLRGDRGGCGEE------GGSHLRRCRGPDGFDDDKDGLPEWCLDD XP_004840233.1/1-1035 GWREHGERRRKFDFDMRGERGGCGEEEGRGGGGSSHLRRCHGPDGFDDDKDGLPEWCLND ************:**:**:******* *.******:. :**::**********:* ENSMUSP00000031727/1-1044 EDEEMGTFDASGAFLPLKKGPKEAIPEEQELDFRGLEEEEEEEEEPSEGVDEERPEAGGK ENSRNOP00000001912/1-1042 EDEEMGTFDASGAFLPLKKGPKEPIPEEQELDFQGL---EEEEEEPSDGVDEEGPEAGGK ENSP00000275732/1-1035 EDEEMGTFDASGAFLPLKKGPKEPIPEEQELDFQGL----EEEEEPSEGLEEEGPEAGGK ENSCPOP00000012247/1-1015 EDEEMGTFDASGAFLPLKKGPKEPIPEEQELDFQGL---EEEEEEAQEGLDEEQPEAGEK XP_004840233.1/1-1035 EDEEMGTFDASGAFLPLKKGPKDPIPEEQELDFQGL---EEEEEEPSEGLDEERPEAGGK **********************:.*********:** *****..:*::** **** * ENSMUSP00000031727/1-1044 EATPLPPP-ENSSSPSSLPALGPLWTTNEEGGEAVEKELPPAEGDELRGLSLSPRISSPP ENSRNOP00000001912/1-1042 EVTPLPPS-EKSSSPSSLPALGPLWTANEDG-EAVEKELPPAEGDEMRGLPLSPRISSPP ENSP00000275732/1-1035 ELTPLPPQEEKSSSPSPLPTLGPLWGTNGDGDETAEKEPPAAE-DDIRGIQLSPGVGSSA ENSCPOP00000012247/1-1015 ELPPLPPP-EKSTSPSPLPTLGPLWGTNGEGDEAVEKELPAAEGDDMQRIQLSPSIGSPP XP_004840233.1/1-1035 ELPPLPPP-EKSSSPSPLPTLGPLWGTNGESDEAVEKELPAAE-DDMRRIQLSPGVGSPP * .**** *:*:***.**:***** :* :. *:.*** *.** *::: : *** :.*.. ENSMUSP00000031727/1-1044 -GPPGDLEDEEGLKHLQQEAEKLVASLQDSSLEEEQFTAAMQTQGLRHSTAATALPLSHG ENSRNOP00000001912/1-1042 AGPPADLEDEEGLKHLQQEAEKLVASLQDSSLEEEQFTAAMQTQGLRHSTAATALPLSHG ENSP00000275732/1-1035 -GPPGDLEDDEGLKHLQQEAEKLVASLQDSSLEEEQFTAAMQTQGLRHSAAATALPLSHG ENSCPOP00000012247/1-1015 -PPSGDLEDEEGLKHLQQEAEKLVASLQDSSLEEEQFTAAMQSQGLRHPTAATALPLSHG XP_004840233.1/1-1035 -APPGDLEDEEGLKHLQQEAEKLVASLQDSSLEEEQFTAAMQTQGLRHSTAATALPLSHG *..****:********************************:*****.:********** ENSMUSP00000031727/1-1044 AARKWFYKDPQGEIQGPFTTQEMAEWFQAGYFSMSLLVKRGCDEGFQPLGEVIKMWGRVP ENSRNOP00000001912/1-1042 AARKWFYKDPQGEIQGPFTTQEMAEWFQAGYFSMSLLVKRGCDEGFQPLGEVIKMWGRVP ENSP00000275732/1-1035 AARKWFYKDPQGEIQGPFTTQEMAEWFQAGYFSMSLLVKRGCDEGFQPLGEVIKMWGRVP ENSCPOP00000012247/1-1015 AARKWFYKDPQGEIQGPFTTQEMAEWFQAGYFSMSLLVKRGCDEGFQPLGEVIKMWGRVP XP_004840233.1/1-1035 AARKWFYKDPQGEIQGPFTTQEMAEWFQAGYFSMSLLVKRGCDEGFQPLGEVIKMWGRVP ************************************************************ ENSMUSP00000031727/1-1044 FAPGPSPPPLLGNMDQERLKKQQELAAAALYQQLQHQHFLQLVGSRQLPQCTTLREKAAM ENSRNOP00000001912/1-1042 FAPGPSPPPLLGNMDQERLKKQQELAAAALYQQLQHQHFLQLVGSRQLPQCATLREKAAM ENSP00000275732/1-1035 FAPGPSPPPLLGNMDQERLKKQQELAAAALYQQLQHQQFLQLVSSRQLPQCA-LREKAAL ENSCPOP00000012247/1-1015 FAPGPSPPPLLGNMDQERLKKQQELATAALYQQLQHQQFLQLVGSRQLSPCS-LREKAAM XP_004840233.1/1-1035 FAPGPSPPPLLGNMDQERLKKQQELAAAALYQQLQHQQFLQLVGSRQLPPCS-LREKAAM **************************:**********:*****.****. *: ******: ENSMUSP00000031727/1-1044 GDLTPP-------QQQQLTTFLQQLQALKTPRGGDQNLLPTMSRSLSVPDSGPLWDLHTS ENSRNOP00000001912/1-1042 GDLTPP--------QQQLTTFLQQLQALKTPRGGDQNLLPTMSRSLSVPDSGPLWDLHTS ENSP00000275732/1-1035 GDLTPPPPPPPQQQQQQLTAFLQQLQALKPPRGGDQNLLPTMSRSLSVPDSGRLWDVHTS ENSCPOP00000012247/1-1015 GDLAPP-------QQQQLTTFLQQLQALKPPRGGDQNLLPTISRSLSVPDSSPLWDIHTS XP_004840233.1/1-1035 GDLAPP-------QQQQLTTFLQQLQALKPSRGGDQNLLPTISRSMSVPDSSPLWDVHTS ***:** *****:*********..**********:***:*****. ***:*** ENSMUSP00000031727/1-1044 ASSQSGGEASLWDIPINSSTQGPILEQLQLQHKFQERREVELRAKREEEERKRREEKRRQ ENSRNOP00000001912/1-1042 ASSQSGGEASLWDIPINSSTQGPILEQLQLQHKFQERREVELRVKREEEERKRREEKRR- ENSP00000275732/1-1035 ASSQSGGEASLWDIPINSSTQGPILEQLQLQHKFQERREVELRAKREEEERKRREEKRR- ENSCPOP00000012247/1-1015 ASSQSGGEASLWDIPINSSTQGPILEQLQLQHKFQERREVELRVKREEEERKRREEKR-- XP_004840233.1/1-1035 ASSQSGGEASLWDIPINSSTQGPILEQLQLQHKFQERREVELRAKREEEERKRREEKRR- *******************************************.************** ENSMUSP00000031727/1-1044 QQQQQEEQKRRQEEEELFRRKQVRQQELLLKLLQQQQ----ATNVPVPPAPSSPPPLWAG ENSRNOP00000001912/1-1042 QQQQQEEQKRRQEEEELFRRKQVRQQELLLKLLQQQQ----ATNVPVPPAPSSPPPLWAG ENSP00000275732/1-1035 -QQQQEEQKRRQEEEELFRRKHVRQQELLLKLLQQQQ------AVPVPPAPSSPPPLWAG ENSCPOP00000012247/1-1015 ----------------LFRRKQVRQQELLLKLLQQQQQ--ASTTVPVPPAPSSPPPLWAG XP_004840233.1/1-1035 -QQQQEEHKRRQEEEELFRRKQVRQQELLLKLLQQQQQQQASAAVPVPPAPSSPPPLWAG *****:*************** **************** ENSMUSP00000031727/1-1044 LAKQGLSMKTLLELQMESERQLHKQAAPREPLRAQAPNHRVQLGGLGSAPLNQWVSEAGP ENSRNOP00000001912/1-1042 LAKQGLSMKTLLELQMESERQLHKQPAPREPLRAQAPNHRVQLGGLGTAPLNQWVSEAGP ENSP00000275732/1-1035 LAKQGLSMKTLLELQLEGERQLHKQPPPREPARAQAPNHRVQLGGLGTAPLNQWVSEAGP ENSCPOP00000012247/1-1015 LAKQGLSMKTLLELQLEGERQLHKPPVPREPPRAQAPNHRSQLGGLGAAPLNQWVSEAGP XP_004840233.1/1-1035 LAKQGLSMKTLLELQLEGERQLHKPPVPREPPRAQAPNHRSQLGGLGAAPLNQWVSEAGP ***************:*.****** . **** ******** ******:************ ENSMUSP00000031727/1-1044 LWGGPDKSGGSSGGNLGLWEDTLKSGGSLARSLGLKSSRSSPSLSDSYSHLSGRPVRKKT ENSRNOP00000001912/1-1042 LWGGPDKSGGSSSGNLGLWEDTLKSGGSLARSLGLKNSRSSPSLSDSYSHLSGRPVRKKT ENSP00000275732/1-1035 LWGGPDKSGGGSSG-LGLWEDTPKSGGSLVRGLGLKNSRSSPSLSDSYSHLSGRPIRKKT ENSCPOP00000012247/1-1015 LWGGPDKSGGSGGGSLGLWEDTLKSSGSLARGLGLKNSRSSPSLSDSYSHLSGRPVRKKT XP_004840233.1/1-1035 LWGGPDKSGGSGGGSLGLWEDPLKSSGSLARGLGLKNSRSSPSLSDSYSHLSGRPVRKKT **********...* ******. **.***.*.****.******************:**** ENSMUSP00000031727/1-1044 EEEEKLLKLLQGIPRPQDGFTQWCEQMLHTLSTAGSLDVPMAVAILKEVESPYDVHDYIR ENSRNOP00000001912/1-1042 EEEEKLLKLLQGIPRPQDGFTQWCEQMLHTLSTTSSLDVPMAVAILKEVESPYDVHDYIR ENSP00000275732/1-1035 EEEEKLLKLLQGIPRPQDGFTQWCEQMLHTLSATGSLDVPMAVAILKEVESPYDVHDYIR ENSCPOP00000012247/1-1015 EEEEKLLKLLQGIPRPQDGFTQWCEQMLHTLSTTGSLDVPMAVAILKEVESPYDVHDYIR XP_004840233.1/1-1035 EEEEKLLKLLQGIPRPQDGFTQWCEQMLHTLSTTGSLDVPMAVAILKEVESPYDVHDYIR ********************************::.************************* ENSMUSP00000031727/1-1044 SCLGDTLEAKEFAKQFLERRAKQKASQQR---QQQQQQQQQQQQEAWLSSTSLQTAFQAN ENSRNOP00000001912/1-1042 SCLGDTLEAKEFAKQFLERRAKQKASQQRQQQQQQQQQQQQQQQEAWLSSSSLQTAFQAN ENSP00000275732/1-1035 SCLGDTLEAKEFAKQFLERRAKQKASQQR-----------QQQQEAWLSSASLQTAFQAN ENSCPOP00000012247/1-1015 SCLGDTLEAKEFAKQFLERRAKQKASQQR----------QHQQQEVWLSSASLQTAFQAN XP_004840233.1/1-1035 SCLGDTLEAKEFAKQFLERRAKQKASQQR-----------QHQQQVWLSSASLQTAFQAN ***************************** ::**:.****:********* ENSMUSP00000031727/1-1044 HSTKLGPGEGSKAKRRALMLHSDPSILGYSLHGPSGEIESVDDY ENSRNOP00000001912/1-1042 HSTKLGPGEGSKAKRRALMLHSDPSILGYSLHGPSGEIESVDDY ENSP00000275732/1-1035 HSTKLGPGEGSKAKRRALMLHSDPSILGYSLHGSSGEIESVDDY ENSCPOP00000012247/1-1015 HSTKLGPGEGTKAKRRALMLHSDPSILGYSLHGPSGEIESVDDY XP_004840233.1/1-1035 HSTKLGPGEGTKAKRRALMLHSDPSILGYSLHGPSGEIESVDDY **********:**********************.**********