CLUSTAL W(1.81) multiple sequence alignment ENSMUSP00000099138/1-1062 MEPDTATEAATVAVSDARATVVVVEDEQPGPSTFKEEGAAAAATEGTTATEKGE-KKEKI ENSRNOP00000060122/1-1062 MEPDTATEAATVAASDARATIVVLEDEQPGPSTFKEEGAAAAATEATTATEKGE-KKEKI XP_004860087.1/1-1042 MEPDTAAVAATVAAADATATIVVIEDEQPGPSTSKEEGAAAAATEATATTEKGEKKKEKN ENSCPOP00000012245/1-986 ------------------------------------------------------------ ENSP00000360163/1-1054 MEQDTAAVAATVAAADATATIVVIEDEQPGPSTSQEEGAAAAATEATAATEKGEKKKEKN ENSMUSP00000099138/1-1062 TSPFQLKLAAKASKSEKEMDPEYEEKMVNMPLKADRAKRFEFLLKQTELFAHFIQPSAQK ENSRNOP00000060122/1-1062 TSPFQLKLAAKTSKSEKEMDPEYEEKMVNIPLKADRAKRFEFLLKQTELFAHFIQPSAQK XP_004860087.1/1-1042 ISPFQLKLATKASKSEKEMDPEYEEKM-----KADRAKRFEFLLKQTELFAHFIQPSAQK ENSCPOP00000012245/1-986 -------------KSEKEMDPEYEEKM-----KADRAKRFEFLLKQTELFAHFIQPSAQK ENSP00000360163/1-1054 VSSFQLKLAAKAPKSEKEMDPEYEEKM-----KADRAKRFEFLLKQTELFAHFIQPSAQK ************** **************************** ENSMUSP00000099138/1-1062 SPTSPLNMKLARPRVKKDDKQSLISVGD---YRHRRTEQEEDEELLSESRKTSNVCVRFE ENSRNOP00000060122/1-1062 SPTSPLNMKLARPRVKKDDKQSLISVGD---YRHRRTEQEEDEELLSESRKTSNVCVRFE XP_004860087.1/1-1042 SPTFPLSMKLGRPRIKKDEKQSLISAGD---YRHRRTEQEEDEELLLESRKTSSVCVRFE ENSCPOP00000012245/1-986 SPTFPLNMKFRRPRAKKDEKQSLISAGEYFSYRHRRTEQEEDEELLSESRKTSSVCVRFE ENSP00000360163/1-1054 SPTSPLNMKLGRPRIKKDEKQSLISAGD---YRHRRTEQEEDEELLSESRKTSNVCIRFE *** **.**: *** ***:******.*: *************** ******.**:*** ENSMUSP00000099138/1-1062 VSPSYVKGGPLRDYQIRGLNWLISLYENGVNGILADEMGLGKTLQTIALLGYLKHYRNIP ENSRNOP00000060122/1-1062 VSPSYVKGGPLRDYQIRGLNWLISLYENGVNGILADEMGLGKTLQTIALLGYLKHYRNFP XP_004860087.1/1-1042 VSPSYVKGGALRDYQIRGLNWLISLYENGVNGILADEMGLGKTLQTIALLGYLKHYRNIP ENSCPOP00000012245/1-986 VSPSYVKGGALRDYQIRGLNWLISLYENGVNGILADEMGLGKTLQTIALLGYLKHYRSIP ENSP00000360163/1-1054 VSPSYVKGGPLRDYQIRGLNWLISLYENGVNGILADEMGLGKTLQTIALLGYLKHYRNIP *********.***********************************************.:* ENSMUSP00000099138/1-1062 GPHMVLVPKSTLHNWMNEFKRWVPSLRVICFVGDKDVRAAFIRDEMMPGEWDVCVTSYEM ENSRNOP00000060122/1-1062 GPHMVLVPKSTLHNWMNEFKRWVPSLRVICFVGDKDVRAAFIRDEMMPGEWDVCVTSYEM XP_004860087.1/1-1042 GPHMVLVPKSTLHNWMNEFKRWVPSLRVICFVGDKDARAAFICDEMIPGEWDVCVTSYEM ENSCPOP00000012245/1-986 GPHMVLVPKSTLHNWMNEFKRWVPSLRVICFVGDKDARAAFIRDEMMPGEWDVCVTSYEM ENSP00000360163/1-1054 GPHMVLVPKSTLHNWMNEFKRWVPSLRVICFVGDKDARAAFIRDEMMPGEWDVCVTSYEM ************************************.***** ***:************* ENSMUSP00000099138/1-1062 VIKEKSVFKKFHWRYLVIDEAHRIKNEKSKLSEIVREFKSTNRLLLTGTPLQNNLHELWA ENSRNOP00000060122/1-1062 VIKEKSVFKKFHWRYLVIDEAHRIKNEKSKLSEIVREFKSTNRLLLTGTPLQNNLHELWA XP_004860087.1/1-1042 VIKEKSVFKKFHWRYVVIDEAHRIKNEKSKLSEIVREFKSTNRLLLTGTPLQNNLHELWA ENSCPOP00000012245/1-986 VIKEKSVFKKFHWRYLVIDEAHRIKNEKSKLSEIVREFKSTNRLLLTGTPLQNNLHELWA ENSP00000360163/1-1054 VIKEKSVFKKFHWRYLVIDEAHRIKNEKSKLSEIVREFKSTNRLLLTGTPLQNNLHELWA ***************:******************************************** ENSMUSP00000099138/1-1062 LLNFLLPDVFNSADDFDSWFDTKNCLGDQKLVERLHAVLKPFLLRRIKTDVEKSLPPKKE ENSRNOP00000060122/1-1062 LLNFLLPDVFNSADDFDSWFDTKNCLGDQKLVERLHAVLKPFLLRRIKTDVEKSLPPKKE XP_004860087.1/1-1042 LLNFLLPDVFNSSDDFDSWFDTKNCFGDQKLVERLHAVLKPFLLRRIKTDVERSLPPKKE ENSCPOP00000012245/1-986 LLNFLLPDVFNSADDFDSWFDTKNCFGDQKLVERLHAVLKPFLLRRIKTDVEKSLPPKKE ENSP00000360163/1-1054 LLNFLLPDVFNSADDFDSWFDTKNCLGDQKLVERLHAVLKPFLLRRIKTDVEKSLPPKKE ************:************:**************************:******* ENSMUSP00000099138/1-1062 IKIYLGLSKMQREWYTKILMKDIDVLNSSGKMDKMRLLNILMQLRKCCNHPYLFDGAEPG ENSRNOP00000060122/1-1062 IKIYLGLSKMQREWYTKILMKDIDVLNSSGKMDKMRLLNILMQLRKCCNHPYLFDGAEPG XP_004860087.1/1-1042 IKIYLGLSKMQREWYTKILMKDIDVLNSAGKMDKMRLLNILMQLRKCCNHPYLFDGAEPG ENSCPOP00000012245/1-986 IKIYLGLSKMQREWYTKILMKDIDVLNSAGKMDKMRLLNILMQLRKCCNHPYLFDGAEPG ENSP00000360163/1-1054 IKIYLGLSKMQREWYTKILMKDIDVLNSSGKMDKMRLLNILMQLRKCCNHPYLFDGAEPG ****************************:******************************* ENSMUSP00000099138/1-1062 PPYTTDEHIVGNSGKMVALDKLLARIKEQGSRVLIFSQMTRLLDILEDYCMWRGYEYSRL ENSRNOP00000060122/1-1062 PPYTTDEHIVSNSGKMVALDKLLARIKEQGSRVLIFSQMTRLLDILEDYCMWRGYEYCRL XP_004860087.1/1-1042 PPYTTDEHIVSNSGKMVVLDKLLSRLKEQGSRVLIFSQMTRLLDILEDYCMWRGYEYCRL ENSCPOP00000012245/1-986 PPYTTDEHIVSNSGKMVVLDKLLARLKDQGSRVLIFSQMTRLLDILEDYCMWRGYEYCRL ENSP00000360163/1-1054 PPYTTDEHIVSNSGKMVVLDKLLAKLKEQGSRVLIFSQMTRLLDILEDYCMWRGYEYCRL **********.******.*****:::*:*****************************.** ENSMUSP00000099138/1-1062 DGQTPHEERE------------EAIDAFNAPNSSKFIFMLSTRAGGLGINLASADVVILY ENSRNOP00000060122/1-1062 DGQTPHEERE------------EAIEAFNAPNSSKFIFMLSTRAGGLGINLASADVVILY XP_004860087.1/1-1042 DGQTPHEERE------------EAIEAFNVPNSSKFIFMLSTRAGGLGINLASADVVILY ENSCPOP00000012245/1-986 DGQTPHEERE------------EAIEAFNVPNSSKFIFMLSTRAGGLGINLASADVVILY ENSP00000360163/1-1054 DGQTPHEEREDKFLEVEFLGQREAIEAFNAPNSSKFIFMLSTRAGGLGINLASADVVILY ********** ***:***.****************************** ENSMUSP00000099138/1-1062 DSDWNPQVDLQAMDRAHRIGQKKPVRVFRLITDNTVEERIVERAEIKLRLDSIVIQQGRL ENSRNOP00000060122/1-1062 DSDWNPQVDLQAMDRAHRIGQKKPVRVFRLITDNTVEERIVERAEIKLRLDSIVIQQGRL XP_004860087.1/1-1042 DSDWNPQVDLQAMDRAHRIGQKKPVRVFRLITDDTVEERIVERAEIKLRLDSIVIQQGRL ENSCPOP00000012245/1-986 DSDWNPQVDLQAMDRAHRIGQKKPVRVFRLITDNTVEERIVERAEIKLRLDSIVIQQGRL ENSP00000360163/1-1054 DSDWNPQVDLQAMDRAHRIGQKKPVRVFRLITDNTVEERIVERAEIKLRLDSIVIQQGRL *********************************:************************** ENSMUSP00000099138/1-1062 IDQQSNKLAKEEMLQMIRHGATHVFACKESELTDEDIVTILERGEKKTAEMNERMQKMGE ENSRNOP00000060122/1-1062 IDQQSNKLAKEEMLQMIRHGATHVFACKESELTDEDIVTILERGEKKTAEMNERMQKMGE XP_004860087.1/1-1042 IDQQSNKLAKEEMLQMIRHGATHVFASKETELTDEDITTILERGEKKTAEMNERLHKMGE ENSCPOP00000012245/1-986 IDQQSNKLAKEEMLQMIRHGATHVFASKESELTDEDITTILERGEKKTAEMNERMQKMGE ENSP00000360163/1-1054 IDQQSNKLAKEEMLQMIRHGATHVFASKESELTDEDITTILERGEKKTAEMNERLQKMGE **************************.**:*******.****************::**** ENSMUSP00000099138/1-1062 SSLRNFRMDLEQSLYKFEGEDYREKQKLGTVEWIEPPKRERKANYAVDAYFREALRVSEP ENSRNOP00000060122/1-1062 SSLRNFRMDLEQSLYKFEGEDYREKQKLGTVEWIEPPKRERKANYAVDAYFREALRVSEP XP_004860087.1/1-1042 SSLRNFRMDIEQSLYKFEGEDYREKQKLGMVEWIEPPKRERKANYAVDAYFREALRVSEP ENSCPOP00000012245/1-986 SSLRNFRMDIEQSLYKFEGEDYREKQKLGMVEWIEPPKRERKANYAVDAYFREALRVSEP ENSP00000360163/1-1054 SSLRNFRMDIEQSLYKFEGEDYREKQKLGMVEWIEPPKRERKANYAVDAYFREALRVSEP *********:******************* ****************************** ENSMUSP00000099138/1-1062 KIPKAPRPPKQPNVQDFQFFPPRLFELLEKEILYYRKTIGYKVPRNPEIPNPAIAQREEQ ENSRNOP00000060122/1-1062 KVPKAPRPPKQPNVQDFQFFPPRLFELLEKEILYYRKTIGYKVPRNPELPNPAIAQREEQ XP_004860087.1/1-1042 KIPKAPRPPKQPNVQDFQFFPPRLFELLEKEILYYRKTIGYKVPRNPEIPNPALVQREEQ ENSCPOP00000012245/1-986 KIPKAPRPPKQPNVQDFQFFPPRLFELLEKEILYYRKTIGYKVPRNPEMPNPALAQREEQ ENSP00000360163/1-1054 KIPKAPRPPKQPNVQDFQFFPPRLFELLEKEILYYRKTIGYKVPRNPDIPNPALAQREEQ *:*********************************************::****:.***** ENSMUSP00000099138/1-1062 KKIDGAEPLTPQETEEKDKLLTQGFTNWTKRDFNQFIKANEKYGRDDIDNIAREVEGKSP ENSRNOP00000060122/1-1062 KKIDGAEPLTPQESEEKDKLLTQGFTNWTKRDFNQFIKANEKYGRDDIDNVAREVEGKSP XP_004860087.1/1-1042 KKIDGAEPLTLEETEEKEKLLTQGFTNWTKRDFNQFIKANEKYGRDDIDNIAREVEGKSP ENSCPOP00000012245/1-986 KKIDGAEPLTLEETEEKEKLLTQGFTNWTKRDFNQFIKANEKYGRDDIDNIAREVEGKSP ENSP00000360163/1-1054 KKIDGAEPLTPEETEEKEKLLTQGFTNWTKRDFNQFIKANEKYGRDDIDNIAREVEGKSP ********** :*:***:********************************:********* ENSMUSP00000099138/1-1062 EEVMEYSAVFWERCNELQDIEKIMAQIERGEARIQRRISIKKALDAKIARYKAPFHQLRI ENSRNOP00000060122/1-1062 EEVMEYSAVFWERCNELQDIEKIMAQIERGEARIQRRISIKKALDAKIARYKAPFHQLRI XP_004860087.1/1-1042 EEVMEYSAVFWERCSELQDIEKIMAQIERGEARIQRRISIKKALDAKIARYKAPFHQLRI ENSCPOP00000012245/1-986 EEVMEYSAVFWERCNELQDIEKIMAQIERGEARIQRRISIKKALDAKIARYKAPFHQLRI ENSP00000360163/1-1054 EEVMEYSAVFWERCNELQDIEKIMAQIERGEARIQRRISIKKALDAKIARYKAPFHQLRI **************.********************************************* ENSMUSP00000099138/1-1062 QYGTSKGKNYTEEEDRFLICMLHKMGFDRENVYEELRQCVRNAPQFRFDWFIKSRTAMEF ENSRNOP00000060122/1-1062 QYGTSKGKNYTEEEDRFLICMLHKMGFDRENVYEELRQCVRNAPQFRFDWFIKSRTAMEF XP_004860087.1/1-1042 QYGTSKGKNYTEEEDRFLICMLHKMGFDRENVYEELRQCVRNAPQFRFDWFIKSRTAMEF ENSCPOP00000012245/1-986 QYGTSKGKNYTEEEDRFLICMLHKMGFDRENVYEELRQCVRNAPQFRFDWFIKSRTAMEF ENSP00000360163/1-1054 QYGTSKGKNYTEEEDRFLICMLHKMGFDRENVYEELRQCVRNAPQFRFDWFIKSRTAMEF ************************************************************ ENSMUSP00000099138/1-1062 QRRCNTLISLIEKENMEIEERERAEKKKRATKTPMSQKRKAESATESSGRKDVKKVKS ENSRNOP00000060122/1-1062 QRRCNTLISLIEKENMEIEERERAEKKKRATKTPMSQKRKAESATESSGKKDVKKVKS XP_004860087.1/1-1042 QRRCNTLISLIEKENMEIEERERAEKKKRATKTPMVKFSAFS---------------- ENSCPOP00000012245/1-986 QRRCNTLISLIEKENMEIEERERAEKKKRATKTPMSQKRKAESATESSGKKDVKKV-- ENSP00000360163/1-1054 QRRCNTLISLIEKENMEIEERERAEKKKRATKTPMVKFSAFS---------------- *********************************** : .