CLUSTAL W(1.81) multiple sequence alignment ENSCPOP00000012066/1-880 --------------------------------------------QVAIKIIDKSQLDAVN ENSRNOP00000062018/1-920 MVMADGPRHLQRGPVRVGFYDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDAVN ENSMUSP00000038761/1-931 MVMADGPRHLQRGPVRVGFYDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDAVN ENSP00000305976/1-926 MVMADGPRHLQRGPVRVGFYDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDAVN XP_004856608.1/1-926 MVMADGPRHLRRGPVRVGFYDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDAVN :*************** ENSCPOP00000012066/1-880 LEKIYREVQIMKMLDHPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEAR ENSRNOP00000062018/1-920 LEKIYREVQIMKMLDHPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEAR ENSMUSP00000038761/1-931 LEKIYREVQIMKMLDHPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEAR ENSP00000305976/1-926 LEKIYREVQIMKMLDHPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEAR XP_004856608.1/1-926 LEKIYREVQIMKMLDHPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLSESEAR ******************************************************.***** ENSCPOP00000012066/1-880 RKFWQILSAVDYCHGRKVVHRDLKAENLLLDNNMNIKIADFGFGNFFKSGELLATWCGSP ENSRNOP00000062018/1-920 RKFWQILSAVDYCHSRKVVHRDLKAENLLLDNSMNIKIADFGFGNFFKTGELLATWCGSP ENSMUSP00000038761/1-931 RKFWQILSAVDYCHGRKVVHRDLKAENLLLDNNMNIKIADFGFGNFFKTGELLATWCGSP ENSP00000305976/1-926 RKFWQILSAVDYCHGRKIVHRDLKAENLLLDNNMNIKIADFGFGNFFKSGELLATWCGSP XP_004856608.1/1-926 RKFWQILSAVDYCHGRKVVHRDLKAENLLLDNNMNIKIADFGFGNFFKSGELLTTWCGSP **************.**:**************.***************:****:****** ENSCPOP00000012066/1-880 PYAAPEVFEGQQYEGPQLDIWSMGVVLYVLVCGALPFDGPTLPMLRQRVLEGRFRIPYFM ENSRNOP00000062018/1-920 PYAAPEVFEGQQYEGPQLDIWSMGVVLYVLVCGALPFDGPTLPILRQRVLEGRFRIPYFM ENSMUSP00000038761/1-931 PYAAPEVFEGQQYEGPQLDIWSMGVVLYVLVCGALPFDGPTLPILRQRVLEGRFRIPYFM ENSP00000305976/1-926 PYAAPEVFEGQQYEGPQLDIWSMGVVLYVLVCGALPFDGPTLPILRQRVLEGRFRIPYFM XP_004856608.1/1-926 PYAAPEVFEGQQYEGPQLDIWSMGVVLYVLVCGALPFDGPTLPILRQRVLEGRFRIPYFM *******************************************:**************** ENSCPOP00000012066/1-880 SEDCEHLIRRMLVLDPSKRLTIAQIKEHKWMLIEVPVQRPVLYPQEQENEPSIGEFNEQV ENSRNOP00000062018/1-920 SEDCEHLIRRMLVLDPSKRLSIAQIKEHKWMLIEVPVQRPILYPQEQENEPSIGEFNEQV ENSMUSP00000038761/1-931 SEDCEHLIRRMLVLDPSKRLSIAQIKEHKWMLIEVPVQRPILYPQEQENEPSIGEFNEQV ENSP00000305976/1-926 SEDCEHLIRRMLVLDPSKRLTIAQIKEHKWMLIEVPVQRPVLYPQEQENEPSIGEFNEQV XP_004856608.1/1-926 SEDCEHLIRRMLVLDPSKRLTIAQIKEHKWMLIEVPVQRPVLYPQEQENEPSIGEFNEQV ********************:*******************:******************* ENSCPOP00000012066/1-880 LRLMHSLGIDQQKTIESLQNKSYNHFAAIYFLLVERLKSHRSSFPVEQRLDGRPRRPSTI ENSRNOP00000062018/1-920 LRLMHSLGIDQQKTIESLQNKSYNHFAAIYFLLVERLKSHRSSFPVEQRLDGRQRRPSTI ENSMUSP00000038761/1-931 LRLMHSLGIDQQKTVESLQNKSYNHFAAIYFLLVERLKSHRSSFPVEQRLDGRQRRPSTI ENSP00000305976/1-926 LRLMHSLGIDQQKTIESLQNKSYNHFAAIYFLLVERLKSHRSSFPVEQRLDGRQRRPSTI XP_004856608.1/1-926 LRLMHSLGIDQQKTIESLQNKSYNHFAAIYFLLVERLKSHRSSFPVEQRLDGRQRRPSTI **************:************************************** ****** ENSCPOP00000012066/1-880 AEQTVAKAHTVGLPVTTSAPAARLMPSALPAPAATVEAFSFPASSCQAEAAFMEAECVDT ENSRNOP00000062018/1-920 AEQTVAKAQTVGLPVTLHPPNLRLMRSTLLPQASNVEAFSFPASSCPAEAAFMEEECVDT ENSMUSP00000038761/1-931 AEQTVAKAQTVGLPVTLHPPNVRLMRSTLLPQASNVEAFSFPTSSCQAEAAFMEEECVDT ENSP00000305976/1-926 AEQTVAKAQTVGLPVTMHSPNMRLLRSALLPQASNVEAFSFPASGCQAEAAFMEEECVDT XP_004856608.1/1-926 AEQTVAKAQTVGLPVTMHSPNMRLIRSTLLPQASNVEAFSFPASSCQAEAAFMEEECVDT ********:******* .* **: *:* . *:.*******:*.* ******* ***** ENSCPOP00000012066/1-880 PKVNGCLLDPVPPVLVRKGCQSLPSNVMETSIDEGLETEGEADEEPGHAFEAFQATRSGQ ENSRNOP00000062018/1-920 PKVNGCLLDPVPPVLVRKGCQSLPSSMMETSIDEGLETEGEAEEDPSQAFEAFQATRSGQ ENSMUSP00000038761/1-931 PKVNGCLLDPVPPVLVRKGCQSLPSSMMETSIDEGLETEGEAEEDPSQAFEAFQATRSGQ ENSP00000305976/1-926 PKVNGCLLDPVPPVLVRKGCQSLPSNMMETSIDEGLETEGEAEEDPAHAFEAFQSTRSGQ XP_004856608.1/1-926 PKVNGCLLDPVPPVLVRKGCQSLPSNMMETSIDEGLETEGEAEEDPSHAFEVFQSTRSGQ *************************.:***************:*:*.:***.**:***** ENSCPOP00000012066/1-880 RRHTLSEVTNQLVMVPGAGKMFSVSDNPSLDSVDSEYDIGSAQRELSFLEDNPSLKDIMA ENSRNOP00000062018/1-920 RRHTLSEVTNQLVVLPRAGKVFSMSDSPSLDSVDSEYDMGSAQRDLNFPEDSPSLKDIML ENSMUSP00000038761/1-931 RRHTLSEVTNQLVVMPGAGKMFSMSDNPSLESVDSEYDMGSAQRDLNFLEDSPSLKDIML ENSP00000305976/1-926 RRHTLSEVTNQLVVMPGAGKIFSMNDSPSLDSVDSEYDMGSVQRDLNFLEDNPSLKDIML XP_004856608.1/1-926 RRHTLSEVTNQLVVVPGAGKIFSMSDNPSLDSVDSEYDMGSAQRELNFLEDNPSLKDIML *************::* ***:**:.*.***:*******:**.**:*.* **.******* ENSCPOP00000012066/1-880 ANPPSPRMTSPFVSLRPTNPAMQALSAQKREAHNRSPVSFREGRRASDTSLTQGIVAFRQ ENSRNOP00000062018/1-920 ANQPSPRMT-PFISLRPANPAMQALSSQRREAHNRSPVSFREGRRASDTSLTQGIVAFRQ ENSMUSP00000038761/1-931 ANQPSPRMTSPFISLRPANPAMQALSSQKREAHNRSPVSFREGRRASDTSLTQGIVAFRQ ENSP00000305976/1-926 ANQPSPRMTSPFISLRPTNPAMQALSSQKREVHNRSPVSFREGRRASDTSLTQGIVAFRQ XP_004856608.1/1-926 ANQPSPHMTSPFISLRPTNPTMQALSSQKREVHNRSPVSFREGRRASDTSLTQGIVAFRQ ** ***:** **:****:**:*****:*:**.**************************** ENSCPOP00000012066/1-880 HLQNLARTKGILELNKVQLLYEQMGPEADPVLASASPQLQDLAGGCPQEEVAPPQEGVPP ENSRNOP00000062018/1-920 HLQNLARTKGILELNKVQLLYEQIRSDADPTLTSTAPQLQDLSSSCPQEEISQRQESVSA ENSMUSP00000038761/1-931 HLQNLARTKGILELNKVQLLYEQMGSNADPTLTSTAPQLQDLSSSCPQEEISQQQESVSS ENSP00000305976/1-926 HLQNLARTKGILELNKVQLLYEQIGPEADPNLAPAAPQLQDLASSCPQEEVSQQQESVST XP_004856608.1/1-926 HLQNLARTKGILELNKVQLLYEQIGSEANPALTSASPQLQDLTSSCPQEEVPRPQESVST ***********************: .:*:* *:.::******:..*****:. **.*.. ENSCPOP00000012066/1-880 LSSSVHPQLSPRQSRETQYLPHRLQKPGLLSKAQNTCQLYCKEAPRSLEQQLQEHRLQQK ENSRNOP00000062018/1-920 LSASMHPQLSPQRSLETPYLQHRLQKPSLLPKAQNACPMYCKEPPRSLEQQLQEHRLQQK ENSMUSP00000038761/1-931 LSASMHPQLSPQQSLETQYLQHRLQKPNLLPKAQSPCPVYCKEPPRSLEQQLQEHRLQQK ENSP00000305976/1-926 LPASVHPQLSPRQSLETQYLQHRLQKPSLLSKAQNTCQLYCKEPPRSLEQQLQEHRLQQK XP_004856608.1/1-926 LSSSVHPQLSQRQSLESQYLQHRLQKPSLLSKAQNTCQLYCKEPPRSLEQQLQEHRLQQK *.:*:***** ::* *: ** ******.**.***..* :****.**************** ENSCPOP00000012066/1-880 RLFLQKQSQLQAYFNQMQIAESSYPPPSQQLPLPHPETPPSSQQPPPFSLTQSLSPVLEP ENSRNOP00000062018/1-920 RLFLQKQSQLQAYFNQMQIAERSYPGPTQQLALPHPETAPTPQQPPSFSLTQALSPVLEP ENSMUSP00000038761/1-931 RLFLQKQSQLQAYFNQMQIAESSYPGPSQQLALPHQETPLTSQQPPSFSLTQALSPVLEP ENSP00000305976/1-926 RLFLQKQSQLQAYFNQMQIAESSYPQPSQQLPLPRQETPPPSQQAPPFSLTQPLSPVLEP XP_004856608.1/1-926 RLFLQKQSQLQAYFNQMQIAESSYP-PSQQLPLPHQETPPSSQQPPPFGLTQPLSPVLEP ********************* *** *:***.**: **. ..**.*.*.***.******* ENSCPOP00000012066/1-880 SSEQMQYSPFLGQYEEMQLRPLPSTPSARAAPPLPTQL---QQQPPPSPPPPPQQPGAAP ENSRNOP00000062018/1-920 SSEQMRFSSFLSQYPDMQLQPLPSTPSPRAPPPLPSQLQQQQQPPPPPPPPPPQQPGATP ENSMUSP00000038761/1-931 SSEQMQFSSFLSQYPEMQLQPLPSTPGPQAPPPLPSQLQQHQQPPPPPPPPPPQQPGAAP ENSP00000305976/1-926 SSEQMQYSPFLSQYQEMQLQPLPSTSGPRAAPPLPTQLQQ-QQPPPPPPPPPPRQPGAAP XP_004856608.1/1-926 SSEQMQYSPFLDQYEEMQLQPLPSTPSPRAPPPLPTQLQ--QQPPPPPPPPPPQQPGAAP *****::*.**.** :***:*****...:*.****:** ** ***.*****:****:* ENSCPOP00000012066/1-880 APLQFSYQTCELSSATSSAPDYPAPCQYPVDGAPQSSLTGPDCPRSSGLQETPSSYDPLA ENSRNOP00000062018/1-920 ASLQFSYQTCGLPSTTSSAPSYPASCHYPVDGAQQSNLTGAECPRSSGLQE--------A ENSMUSP00000038761/1-931 TSLQFSYQTCELPSTTSSVPNYPASCHYPVDGAQQSNLTGADCPRSSGLQDTASSYDPLA ENSP00000305976/1-926 APLQFSYQTCELPSAASPAPDYPTPCQYPVDGAQQSDLTGPDCPRSPGLQEAPSSYDPLA XP_004856608.1/1-926 APLQFSYQTCELPSAASSAPDYPAPCQYPVDGAQQSNLTGLDCPRSSGLQEAPSSYDPLA :.******** *.*::*..*.**:.*:****** **.*** :****.***: * ENSCPOP00000012066/1-880 LSELPGLFDCEMLDAVDPQHNGYV--LVN-- ENSRNOP00000062018/1-920 LSALPGLFDYEMVEAVDPQHNGVACPISR-- ENSMUSP00000038761/1-931 LSELPGLFDCEMVEAVDPQHNGVVSCLARET ENSP00000305976/1-926 LSELPGLFDCEMLDAVDPQHNGYV--LVN-- XP_004856608.1/1-926 LSELPGLFDCEMLDAVDPQHNGVACPISR-- ** ****** **::******** . : .