CLUSTAL W(1.81) multiple sequence alignment ENSMUSP00000134675/1-1234 MSKERPKRNIIQKKYDDSDGIPWSEERVVRKVLYLSLKEFKNAQKRQHGEGLAGSLKAVN ENSRNOP00000067055/1-1234 MSKERPKRNIIQKKYDDSDGIPWSEERVVRKVLYLSLKEFKNAQKRQHGEGIAGSLKTVN ENSP00000341280/1-1246 MSKERPKRNIIQKKYDDSDGIPWSEERVVRKVLYLSLKEFKNSQKRQHAEGIAGSLKTVN XP_004847715.1/1-1253 MSKERPKRNIIQKKYDDSDGIPWSEERVVRKVLYLSLKEFKDAQKRQHGDSIAGSLKTVN ENSCPOP00000011943/1-1247 MSKERPKRNIIHKKYDDSDGIPWSEERVVRKVLYLSLKEFKNAQKRQHGDSIAGSLKTVN ***********:*****************************::*****.:.:*****:** ENSMUSP00000134675/1-1234 GLLGNAQAKALGPASEQSENEKDDASQVSSTSNDVSSSDFEEGPSRKRPRLQAQRKFAQS ENSRNOP00000067055/1-1234 GLLGNDQSKALGPASEQSENEKDDASQVSSTSNDVSSSDFEEGPSRKRPRLQAQRKFAQS ENSP00000341280/1-1246 GLLGNDQSKGLGPASEQSENEKDDASQVSSTSNDVSSSDFEEGPSRKRPRLQAQRKFAQS XP_004847715.1/1-1253 GLLGNDQSKGLGPASEQSENEKDDASQVSSTSNDVSSSDFEEGPSRKRPRLQAQRKFAQS ENSCPOP00000011943/1-1247 GLLGNDQSKGLGPASEQSENEKDDASQVSSTSNDVSSSDFEEGPSRKRPRLQAQRKFAQS ***** *:*.************************************************** ENSMUSP00000134675/1-1234 QPNSPSTTPVKIVEPLLPPPATQISDLSKRKPKTEDFLTFLCLRGSPALPNSMVYFGSSQ ENSRNOP00000067055/1-1234 QPNSPSTTPVKTVEPLLPPPATHISDLSKRKPKTEDFLTFLCLRGSPALPNSMVYFGSSQ ENSP00000341280/1-1246 QPNSPSTTPVKIVEPLLPPPATQISDLSKRKPKTEDFLTFLCLRGSPALPNSMVYFGSSQ XP_004847715.1/1-1253 QPNSPSTTPVKIVEPLLPPPATQISDLSKRKPKTEDFLTFLCLRGSPALPNSMVYFGSSQ ENSCPOP00000011943/1-1247 QPNSPSTTPVKIVEPLLPPPATQISDLSKRKPKTEDFLTFLCLRGSPALPNNMVYFGSSQ *********** **********:****************************.******** ENSMUSP00000134675/1-1234 DEEDVEEEDDETEDVKATTNNASSSCQSTPRKGKTHKHVHNGHVFNGSSRSAREKEPAHK ENSRNOP00000067055/1-1234 DEEDVEEEDDETEDVKTATNNASSSCQSTPRKGKSHKHVHNGHVFNGSNRSAREKEPAQK ENSP00000341280/1-1246 DEEEVEEEDDETEDVKTATNNASSSCQSTPRKGKTHKHVHNGHVFNGSSRSTREKEPVQK XP_004847715.1/1-1253 DEEDVEEEDDEAEDIKTATNNASSSCQSTPGKGKTHKHVHNGHVFNGSSRSTREKEPVQK ENSCPOP00000011943/1-1247 DEEDVEEEDDETEDVKTATNNASSSCQSTPRKGKTHKHVHNGHVFNGSSRSTREKEPVQK ***:*******:**:*::************ ***:*************.**:*****.:* ENSMUSP00000134675/1-1234 HRSKEATPGKEKHSEPRADSRREQASGAQPTAASAAASSAKGLAANHQPPPSHRSAQDLR ENSRNOP00000067055/1-1234 HRGREATPGKEKHSEHRADGRREQASVAQPTANPPAGSSTKGLAASHQPPPSHRSAQDSR ENSP00000341280/1-1246 HKSKEATPAKEKHSDHRADSRREQASANHPAAAPSTGSSAKGLAATHHHPPLHRSAQDLR XP_004847715.1/1-1253 HKSKEATPAKEKHSDHRADSRREQASATQPSAAPSSVSSAKGLAANYHPPPVHRSAQDFR ENSCPOP00000011943/1-1247 HKSKEATPTKEKHSDHRAESRREQASVTQPTVAPSLGPPAKGLAANHHHPSVHRSAQDLR *:.:**** *****: **:.****** :*:. .. ..:*****.:: *. ****** * ENSMUSP00000134675/1-1234 KQVSKVNGVTRMSSLGAGTNSAKKIREVRPSPSKTVKYTATVTKGTVTYTKAKRELVKET ENSRNOP00000067055/1-1234 KQVSKVNGVTRMSSLGAGTNSAKKIREVRPSPSKTVKYTATVTKGTVTYTKAKRELVKET ENSP00000341280/1-1246 KQVSKVNGVTRMSSLGAGVTSAKKMREVRPSPSKTVKYTATVTKGAVTYTKAKRELVKDT XP_004847715.1/1-1253 KQVSRVNGVTRMSSLGAGAASAKKIREVRPSPSKTVKYTATVTKGTVTYTKAKRELVKES ENSCPOP00000011943/1-1247 KQVSKVNGVTRMSSLGAGATSAKKIREVRPSPSKTVKYTATVTKGTVTYTKAKRELVKET ****:*************. ****:********************:************:: ENSMUSP00000134675/1-1234 KPNHHKPSSAVNHTISGKTESSNAKTRKQVLSLGGASKSTGPAASGLKASSRLNPKSCTK ENSRNOP00000067055/1-1234 KPSHHKPSSAVNHTISGKSESSNAKTRKQVLSLGGASTSTAPAASGLKASSRLNPKSCTK ENSP00000341280/1-1246 KPNHHKPSSAVNHTISGKTESSNAKTRKQVLSLGGASKSTGPAVNGLKVSGRLNPKSCTK XP_004847715.1/1-1253 KPNHHKPSSAVNHTISGKTESSNAKTRKQVLSLGGPSKSTGPAASGLKVSGRLNPXSCTK ENSCPOP00000011943/1-1247 KPNHHKPSSAVNHTISGKTESSNAKTRKQVLSLGGASKSTGPAGSGLKVSGRLNPKSCTK **.***************:****************.*.**.** .***.*.**** **** ENSMUSP00000134675/1-1234 EVGGR------QLREGLRNSKRRLEEAQQVDKPQSPPKKMKGVAGNAEAPGKK--ASAAS ENSRNOP00000067055/1-1234 EVGGR------QLREGLRNSKRRLEEAQQVDKQQSPPKKMKGTAGIAEAPGRK--ASAAS ENSP00000341280/1-1246 EVGGRQLREGLQLREGLRNSKRRLEEAHQAEKPQSPPKKMKGAAGPAEGPGKK-----AP XP_004847715.1/1-1253 EVGGR------QLREGLRNSKRRLEEAHQGEKLQSPPKKMKGAAGPAEAPSKTAAAAAAS ENSCPOP00000011943/1-1247 EVGGR------QLREGLRNSKRRLEEVHQAEKLQSPPKKMKGVTGPAEAPSRK--AAAAS ***** ***************.:* :* *********.:* **.*.:. *. ENSMUSP00000134675/1-1234 GEKSLLNGHVKKEVPERSLERNRPKRAAAGKNMLGKQAHGKTEGTPCENRSTSQPESSH- ENSRNOP00000067055/1-1234 GEKSLLNGHVKKEVPERSLERNRPKRAAAGKNMLGKQAHGKSEGTPCENRSTSQPESSH- ENSP00000341280/1-1246 AERGLLNGHVKKEVPERSLERNRPKRATAGKSTPGRQAHGKADSASCENRSTSQPESVH- XP_004847715.1/1-1253 AEKPLLNGQVKKEVPERSWDRSRPKRATAGKSTPGRQAHGKPDSAPCGNRSTSQPEPLHN ENSCPOP00000011943/1-1247 AEKPLLNGHVKKEVPERSLERNRPKRATAGKSTPGKQAHGKPDSASCENRSTSQPEPLHS .*: ****:********* :*.*****:***. *:*****.:.:.* ********. * ENSMUSP00000134675/1-1234 KPHDP-----QGKPEKGSGKSGWAAMDEIPVLRPSAKEFHDPLIYIESVRAQVEKYGMCR ENSRNOP00000067055/1-1234 KPHDP-----QGKPEKGSGKSGWAAMDEIPVLRPSAKEFHDPLIYIESVRAQVEKYGMCR ENSP00000341280/1-1246 KPQDS------GKAEKGGGKAGWAAMDEIPVLRPSAKEFHDPLIYIESVRAQVEKFGMCR XP_004847715.1/1-1253 KPHDPPPPLPPGRPEKGGGRSGREAMDEIPVLRPSAKELHDPLIYIKSVRAQVEKYGMCR ENSCPOP00000011943/1-1247 KPHDP----PPGKPEKGGGRSAWAAMDEIPVLRPSAKEFHDPLIYIESVRAQVEKYGMCR **:*. *:.***.*::. **************:*******:********:**** ENSMUSP00000134675/1-1234 VIPPPDWRPECKLNDEMRFVTQIQHIHKLGRRWGPNVQRLACIKKHLRSQGITMDELPLI ENSRNOP00000067055/1-1234 VIPPPDWRPECKLNDEMRFVTQIQHIHKLGRRWGPNVQRLACIKKHLRSQGITMDELPLI ENSP00000341280/1-1246 VIPPPDWRPECKLNDEMRFVTQIQHIHKLGRRWGPNVQRLACIKKHLKSQGITMDELPLI XP_004847715.1/1-1253 VIPPPDWRPECKLNDEMRFVTQIQQIHKLGRRWGPNVQRLACIKKHLRSQGITMDELPLI ENSCPOP00000011943/1-1247 VIPPPDWRPECKLNDEMRFVTQIQHIHKLGRRWGPNVQRLACIKKHLRSQGITMDELPLI ************************:**********************:************ ENSMUSP00000134675/1-1234 GGCELDLACFFRLINEMGGMQQVTDLKKWNKLADMLRIPKTAQDRLAKLQEAYCQYLLSY ENSRNOP00000067055/1-1234 GGCELDLACFFRLINEMGGMQQVTDLKKWNKLADMLRIPKTAQDRLAKLQEAYCQYLLSY ENSP00000341280/1-1246 GGCELDLACFFRLINEMGGMQQVTDLKKWNKLADMLRIPRTAQDRLAKLQEAYCQYLLSY XP_004847715.1/1-1253 GGCELDLACFFRLINEMGGMQQVTDLKKWNKLADMLRIPKTAQDRLAKLQEAYCQYLLSY ENSCPOP00000011943/1-1247 GGCELDLACFFRLINEMGGMQQVTDLKKWNKLADMLRIPKTAQDRLAKLQEAYCQYLLSY ***************************************:******************** ENSMUSP00000134675/1-1234 DSLSPEEHRRLEKEVLMEKEILEKRKGPLEGHTESDHHKFHSLPRFEPKNGLVHGVTPRN ENSRNOP00000067055/1-1234 DSLSPEEHRRLEKEVLMEKEILEKRKGPLEGHTENDHHKFHSLPRFEPKNGLIHGVTPRN ENSP00000341280/1-1246 DSLSPEEHRRLEKEVLMEKEILEKRKGPLEGHTENDHHKFHPLPRFEPKNGLIHGVAPRN XP_004847715.1/1-1253 DSLSPEEHRRLEKEVLMEKEILEKRKGPLEGHTENDHHKFHPLPRFEPKNGLIHGVAPRN ENSCPOP00000011943/1-1247 DSLSPEEHRRLEKEVLMEKEILEKRKGPLEGHTENDHHKFHPLPRFEPKNGLIHGVAPRN **********************************.******.**********:***:*** ENSMUSP00000134675/1-1234 GFRSKLKEVGRAPLKTGRRRLFAQEKEVVK-EEEEDKGVLNDFHKCIYKGRSVSLTTFYR ENSRNOP00000067055/1-1234 GFRSKLKEVGRAPLKTGRRRLFAQEKEVVK-EEEEDKGVLDDFYKCIYKGRSVSLTTFYR ENSP00000341280/1-1246 GFRSKLKEVGQAQLKTGRRRLFAQEKEVVK-EEEEDKGVLNDFHKCIYKGRSVSLTTFYR XP_004847715.1/1-1253 GFRSKLKEVGQAPLKTGRRRLFAQEKEVVK-EEEEDKGVLNDFHKCIYKGRSVSLTTFYR ENSCPOP00000011943/1-1247 GFRNKLKEMGQAPLKTGRRRLFAQEKEAVKEEEEEDKGILNDFHKCIYKGRSVSLTTFYR ***.****:*:* **************.** *******:*:**:**************** ENSMUSP00000134675/1-1234 TARNIMNMCFSKEPAPAEIEQEYWRLVEEKDCHVAVHCGKVDTNTHGSGFPVGKSEPFSR ENSRNOP00000067055/1-1234 TARNIMNMCFSKEPAPAEIEQEYWRLVEEKDCHVAVHCGKVDTNTHGSGFPVGKSEPFSR ENSP00000341280/1-1246 TARNIMSMCFSKEPAPAEIEQEYWRLVEEKDCHVAVHCGKVDTNTHGSGFPVGKSEPFSR XP_004847715.1/1-1253 TARNIMNMCFSKEPAPAEIEQEYWRLVEEKDCHVAVHCGKVDTNTHGSGFPVGKSEPFSR ENSCPOP00000011943/1-1247 TARNIMNMCFSKEPAPAEIEQEYWRLVEEKDCHVAVHCGKVDTNTHGSGFPVGKSEPFSR ******.***************************************************** ENSMUSP00000134675/1-1234 HGWNLTVLPNNTGSILRHLGAVPGVTIPWLNIGMVFSTSCWSRDQNHLPYIDYLHTGADC ENSRNOP00000067055/1-1234 HGWNLTVLPNNTGSILRHLGAVPGVTIPWLNIGMVFSTSCWSRDQNHLPYIDYLHTGADC ENSP00000341280/1-1246 HGWNLTVLPNNTGSILRHLGAVPGVTIPWLNIGMVFSTSCWSRDQNHLPYIDYLHTGADC XP_004847715.1/1-1253 HGWNLTVLPNNTGSILRHLGAVPGVTIPWLNIGMVLSTSGWSRDQNHLPYIDYLHTGADC ENSCPOP00000011943/1-1247 HGWNLTVLPNNTGSILRHLGAVPGVTIPWLNIGMVFSTSCWSRDQNHLPYIDYLHTGADC ***********************************:*** ******************** ENSMUSP00000134675/1-1234 IWYCIPAEEENKLEDVVHTLLQGNGTPGLQMLESNVMISPEVLCKKGIKVHRTVQQSGQF ENSRNOP00000067055/1-1234 IWYCIPAEEENKLEDVVHTLLQGNGTPGLQMLESNVMISPEVLCKEGIKVHRTVQQSGQF ENSP00000341280/1-1246 IWYCIPAEEENKLEDVVHTLLQANGTPGLQMLESNVMISPEVLCKEGIKVHRTVQQSGQF XP_004847715.1/1-1253 IWYCIPAEEENKLEDVVHTLLQANGTPGLQMLESNVMISPEVLCKEGIKVHRTVQQSGQF ENSCPOP00000011943/1-1247 IWYCIPAEEENKLEDVVHTLLQANGTPGLQMLESNVMISPEVLCKEGIKVHRTVQQSGQF **********************.**********************:************** ENSMUSP00000134675/1-1234 VVCFPGSFVSKVCCGYNVSETVHFATTQWTSMGFETAKEMKRRHIAKPFSMEKLLYQIAQ ENSRNOP00000067055/1-1234 VVCFPGSFVSKVCCGYNVSETVHFATTQWTSMGFETAKEMKRRHIAKPFSMEKLLYQIAQ ENSP00000341280/1-1246 VVCFPGSFVSKVCCGYSVSETVHFATTQWTSMGFETAKEMKRRHIAKPFSMEKLLYQIAQ XP_004847715.1/1-1253 VVCFPGSFVSKVCCGYSVSETVHFVTTQWTSMGFETAKEMKRRHIAKPFSMEKLLYQIAQ ENSCPOP00000011943/1-1247 VVCFPGSFVSKVCCGYSVSETVHFATTQWTSMGFETAKEMKRRHIAKPFSMEKLLYQIAQ ****************.*******.*********************************** ENSMUSP00000134675/1-1234 AEAKKENGPTLSTISALLDELRDTELRQRRLLFEAGLHSSARY-GSHDGNSTVADGKKKP ENSRNOP00000067055/1-1234 AEAKKENGPTLSTISALLDELRDTELRQRRQLFEAGLHSSARY-GSHDGSSAVADGKKKP ENSP00000341280/1-1246 AEAKKENGPTLSTISALLDELRDTELRQRRQLFEAGLHSSARY-GSHDGSSTVADGKKKP XP_004847715.1/1-1253 AEAKKENGPTLSTISALLDELRDTELRQRRQLFEAGLHLSARYGGSHDGSSAAADGKKKP ENSCPOP00000011943/1-1247 AEAKKENGPTLSTISALLDELRDTELRQRRQLFEAGLHSSARY-GSHDGSSTAADGKKKP ****************************** ******* **** *****.*:.******* ENSMUSP00000134675/1-1234 RKWLQLETSERRCQICQHLCYLSMVVQENENVVFCLECALRHVEKQKSCRGLKLMYRYDE ENSRNOP00000067055/1-1234 RKWLQLETSERRCQICQHLCYLSMVVQENENVVFCLECALRHVEKQKSCRGLKLMYRYDE ENSP00000341280/1-1246 RKWLQLETSERRCQICQHLCYLSMVVQENENVVFCLECALRHVEKQKSCRGLKLMYRYDE XP_004847715.1/1-1253 RKWLQLETSERRCQICQHLCYLSMVVQENENVVFCLECALRHVEKQKSCRGLKLMYRYDE ENSCPOP00000011943/1-1247 RKWLQLETSERRCQICQHLCYLSMVVQENENVVFCLECALRHVEKQKSCRGLKLMYRYDE ************************************************************ ENSMUSP00000134675/1-1234 EQIISLVNQICGKVSGKHGGIENCLNKPTPKRGPRKRATVDVPPSRLPSS---------- ENSRNOP00000067055/1-1234 EQIISLVNQICGKVSGKHGGIENCLNKPTPKRGPRKRATVDVPPSRLPSS---------- ENSP00000341280/1-1246 EQIISLVNQICGKVSGKNGSIENCLSKPTPKRGPRKRATVDVPPSRLSASSSSKSASSSS XP_004847715.1/1-1253 EQIISLVNQICGKVSGKNGSIENCLSKPTPKRGPRKRATVDVPPSRLSASGSSKSASSSS ENSCPOP00000011943/1-1247 EQIISLVNQICGKVSGKNGSIENCLSKPTPKRGPRKRATVDVPPSRLSASGSSKSASSSS *****************:*.*****.*********************.:*