CLUSTAL W(1.81) multiple sequence alignment ENSMUSP00000112632/1-1085 MTDQENNNNISSNPFAALFGSLADAKQFAAIQKEQLKQQSGSVFGSEEEALCNSLHVPAD ENSRNOP00000021321/1-1066 MTDQENNNNISSNPFAALFGSLADAKQFAAIHKEQLKQQS-------------------D XP_004856754.1/1-1066 MTDQENNNNISSNPFAALFGSLADAKQFAAIQKEQLKQQT-------------------D ENSP00000387362/1-1073 MTDQENNNNISSNPFAALFGSLADAKQFAAIQKEQLKQQS-------------------D ENSCPOP00000011851/1-1067 MTDQENNNNISSNPFAALFGSLADAKQFAAIQKEQLKQQS-------------------D *******************************:*******: * ENSMUSP00000112632/1-1085 ELPASPDDSDNSVSESLDEFDYSVSEISRSFRTHQEMCEQLNINHMIQRIFLITLDNSDP ENSRNOP00000021321/1-1066 ELPASPDDSDNSVSESLDEFDYSVSEISRSFRTHQEMCEQLNINHMIQRIFLITLDNSDP XP_004856754.1/1-1066 ELPASPDDSDNSVSESLDEFDYSVAEISRSFRSQQEICEQLNINHMIQRIFLITLDNSDP ENSP00000387362/1-1073 ELPASPDDSDNSVSESLDEFDYSVAEISRSFRSQQEICEQLNINHMIQRIFLITLDNSDP ENSCPOP00000011851/1-1067 ELPASPDDSDNSVSESLDEFDYSVAEISRSFRSQQEICEQLNINHMIQRIFLITLDNSDP ************************:*******::**:*********************** ENSMUSP00000112632/1-1085 SLKSGNGIPSRCVYLEEMAVELEDQDWLDMSNVEQAIFARLLLQDPGNHLISMTSSTTLN ENSRNOP00000021321/1-1066 NLKSGNGIPSRCVYLEEMAVELEDQDWLDMSNVEQAIFARLLLQDPGNHLISMTSSATLN XP_004856754.1/1-1066 SMKSGNGIPSRCVYLEEMAIELEDQDWLDMNNVEQAIFARLLLQDPGNHLINMTSSTTLN ENSP00000387362/1-1073 SLKSGNGIPSRCVYLEEMAVELEDQDWLDMSNVEQALFARLLLQDPGNHLINMTSSTTLN ENSCPOP00000011851/1-1067 SMKSGNGIPSRCVYLEEMAVELEDQDWLDMSNVEQAIFARLLLQDPGNHLINMTSSTTLN .:*****************:**********.*****:**************.****:*** ENSMUSP00000112632/1-1085 LSADRDAGERHIFCYLYSCFQRAKEEITKVPENLLPFAVQCRNLTVSNTRTVLLTPEIYV ENSRNOP00000021321/1-1066 LSADRDAGERHIFCYLYSCFQRAKEEITKVPENLLPFAVQCRNLTVSNTRTVLLTPEIYV XP_004856754.1/1-1066 LSADRDAGERHIFYYLYSCFQRAKEEITKVPENLLPFAVQCRNLTVSNTRTVLLTPEIYV ENSP00000387362/1-1073 LSADRDAGERHIFCYLYSCFQRAKEEITKVPENLLPFAVQCRNLTVSNTRTVLLTPEIYV ENSCPOP00000011851/1-1067 LSADRDAGERHIFCYLYFCFQRAKEEITKVPENLLPFAVQCRNLTVSNTRTVLLTPEIYV ************* *** ****************************************** ENSMUSP00000112632/1-1085 DQNIHEQLVDLMLEAIQGA-------HFEDVTEFLEEVIEALLLDEEVRTFPEVMIPVFD ENSRNOP00000021321/1-1066 DQNIHEQLVDLMLEAIQGA-------HFEDVTEFLEEVIEALLLDEEVRTFPEVMIPVFD XP_004856754.1/1-1066 DQNIPEQLVDLMLEAIQGA-------HFEDVTEFLEEVTEALILDEEVRTFPEVMIPVLD ENSP00000387362/1-1073 DQNIHEQLVDLMLEAIQGAREYMNKIYFEDVTEFLEEVIEALILDEEVRTFPEVMIPVFD ENSCPOP00000011851/1-1067 DQNIHEQLVDLMLEAIQGA-------HFEDVTEFLEGVIEALVLDEEVRTFPEVMIPVFD **** ************** :********* * ***:***************:* ENSMUSP00000112632/1-1085 ILLSRIKDLELCQILLYAYLDILLYFTRQKDMAKVFLEYIQPKDPSNGQMYQKTLLGVIL ENSRNOP00000021321/1-1066 ILLGRIKDLELCQILLYAYLDILLYFTRQKDMAKVFLEYIQPKDPSNGQMYQKTLLGVIL XP_004856754.1/1-1066 ILLSRIKDLELCQILLYAYLDVLLYFTRQKDMAKVFVEYIQPKDPSNGQMYQKTLLGVIL ENSP00000387362/1-1073 ILLGRIKDLELCQILLYAYLDILLYFTRQKDMAKVFVEYIQPKDPTNGQMYQKTLLGVIL ENSCPOP00000011851/1-1067 ILLGRIKDLELCQILLYAYLDILLYFTRQKDMAKVFVEYIQPKDPSNGQMYQKTLLGVIL ***.*****************:**************:********:************** ENSMUSP00000112632/1-1085 NISCLLKTPGVVENHGFFLNPSRSSPQEIKVQEANIHQFMAQFHEKIYQMLKNLLQLSPE ENSRNOP00000021321/1-1066 NISCLLKTPGVVENHGFFLNPSRSSPQEIKVQEANIHQFMAQFHEKIYQMLKNLLQLSPE XP_004856754.1/1-1066 NISCLLKTPGVVENHGYFLNPSRSSPQEIKVQEANIHQFMAQFHEKIYQMLKNLLQLSPE ENSP00000387362/1-1073 SISCLLKTPGVVENHGYFLNPSRSSPQEIKVQEANIHQFMAQFHEKIYQMLKNLLQLSPE ENSCPOP00000011851/1-1067 NISCLLKTPGVVENHGYFLNPSRSSPQEIKVQEANIHQFMAQFHEKIYQMLKNLLQLSPE .***************:******************************************* ENSMUSP00000112632/1-1085 TKHCILFWLGNCLHANAGRTKIWANQMPEIFFQMYASDAFFLNLGAALLKLCQPFCKPRS ENSRNOP00000021321/1-1066 TKHGILFWLGNCLHANAGRTKIWANQMPEIFFQMYASDAFFLNLGAALLKLCQPFCKPRS XP_004856754.1/1-1066 TKHCILSWLGNCLHANAGRTKIWANQMPEIFFQMYASDAFFLNLGAALLKLCQPFCKPRS ENSP00000387362/1-1073 TKHCILSWLGNCLHANAGRTKIWANQMPEIFFQMYASDAFFLNLGAALLKLCQPFCKPRS ENSCPOP00000011851/1-1067 TKHCILSWLGNCLHANAGRTKIWANQMPEIFFQMYASDAFFLNLGAALLKLCQPFCKPRS *** ** ***************************************************** ENSMUSP00000112632/1-1085 SRLLTFNPTYCVLKDLNDEERKIKSVHMR-GLDKETCLIPAVQEPTFPQSYNLVTENLAL ENSRNOP00000021321/1-1066 SRLLTFNPTYCVLKDLNDEERKIKSVHMR-GLDKETCLIPAVQEPVFPQSYNLVTENLAL XP_004856754.1/1-1066 SRLLTFNPTYCTLKELNDEERKIKNVHMR-GLDKETCLIPAVQEPKFPQSYNLVTENLAL ENSP00000387362/1-1073 SRLLTFNPTYCALKELNDEERKIKNVHMR-GLDKETCLIPAVQEPKFPQNYNLVTENLAL ENSCPOP00000011851/1-1067 SRLLTFNPTYCALKELNDEERKIKNVHMRGGLDKETCLIPAVQEPKFPQNYNLVTENLAL ***********.**:*********.**** *************** ***.********** ENSMUSP00000112632/1-1085 TEYTLYLGFHRLHDQMVKINQNLHRLQVAWRDAQQSSSPAADNLREQFERLMTIYLSTKT ENSRNOP00000021321/1-1066 TEYTLYLGFHRLHDQMVKINQNLHRLQVAWRDAQQSSSPAADNLREQFERLMTIYLSTKT XP_004856754.1/1-1066 TEYTLYLGFHRLHDQMVKINQNLHRLQVAWRDAQQSSSPAADNLREQFERLMTIYLSTKT ENSP00000387362/1-1073 TEYTLYLGFHRLHDQMVKINQNLHRLQVAWRDAQQSSSPAADNLREQFERLMTIYLSTKT ENSCPOP00000011851/1-1067 TEYTLYLGFHRLHDQMVKINQNLHRLQVAWRDAQQSSSPAADNLREQFERLMTIYLSTKT ************************************************************ ENSMUSP00000112632/1-1085 AMTEPQMLQNCLNLQVSMAVLLVQLAIGNEGSQPIELSFPLPDGYSSLAYVPEFFADNLG ENSRNOP00000021321/1-1066 AMTEPQMLQNCLNLQVSMAVLLVQLAIGNEGSQPIELSFPLPDGYSSLAYVPEFFADNLG XP_004856754.1/1-1066 AMTEPQMLQNCLNLQVSMAVLLVQLAIGNEGSQPVELTFPLPDGYSSLAYVPEFFADNLG ENSP00000387362/1-1073 AMTEPQMLQNCLNLQVSMAVLLVQLAIGNEGSQPIELTFPLPDGYSSLAYVPEFFADNLG ENSCPOP00000011851/1-1067 AMTEPQMLQNCLNLQVSMAVLLVQLAIGNEGSQPVELTFPLPDGYSSLAYVPEFFADNLG **********************************:**:********************** ENSMUSP00000112632/1-1085 DFLIFLRRFAEDILETSADSLEHVLHFITIFTGSIERMKNPHLRAKLAEVLEAVMPHLDQ ENSRNOP00000021321/1-1066 DFLIFLRRFAEDILETSADSLEHVLHFITIFTGSIERMKNPHLRAKLAEVLEAVMPHLDQ XP_004856754.1/1-1066 DFLIFLRRFADDILETSADSLEHILHFITIFTGSIERMKNPHLRAKLAEVLEAVMPHLDQ ENSP00000387362/1-1073 DFLIFLRRFADDILETSADSLEHVLHFITIFTGSIERMKNPHLRAKLAEVLEAVMPHLDQ ENSCPOP00000011851/1-1067 DFLIFLRRFADDILETSADSLEHVLHFITIFTGSIERMKNPHLRAKLAEVLEAVMPHLDQ **********:************:************************************ ENSMUSP00000112632/1-1085 TPSPLVSSVFHRKRVFCNFPYAPQLAEALIKVFVDIEFTGDPHQFEQKFNYRRPMYPILR ENSRNOP00000021321/1-1066 TPSPLVSSVFHRKRVFCNFPYAPQLSEALIKVFVDIEFTGDPHQFEQKFNYRRPMYPILR XP_004856754.1/1-1066 TPNALLSSVFHRKRVFCNFHYAPQLAEALIKVFVDIEFTGDPHQFEQKFNYRRPMYPILR ENSP00000387362/1-1073 TPNPLVSSVFHRKRVFCNFQYAPQLAEALIKVFVDIEFTGDPHQFEQKFNYRRPMYPILR ENSCPOP00000011851/1-1067 TPNPLVSSVFHRKRVFCNFPYAPQLAEALIKVFVDIEFTGDPHQFEQKFNYRRPMYPILR **..*:************* *****:********************************** ENSMUSP00000112632/1-1085 YMWGTDCYRESIKDLADYASKNLEAMNPPLFLRFLNLLMNDAIFLLDEAIQYLSKIKIQQ ENSRNOP00000021321/1-1066 YMWGTDSYRESIKDLADYASKNLEAMNPPLFLRFLNLLMNDAIFLLDEAIQYLSKIKIQQ XP_004856754.1/1-1066 YMWGTESYRESIKDLADYASKNLEAMNPPLFLRFLNLLMNDAIFLLDEAIQYLSKIKIQQ ENSP00000387362/1-1073 YMWGTDTYRESIKDLADYASKNLEAMNPPLFLRFLNLLMNDAIFLLDEAIQYLSKIKIQQ ENSCPOP00000011851/1-1067 YMWGTDSYRESIKDLADYASKNLEAMNPPLFLRFLNLLMNDAIFLLDEAIQYLSKIKIQQ *****: ***************************************************** ENSMUSP00000112632/1-1085 IEKDRGEWESLTPEARREKEAGLQMFGQLARFHNIMSNETIGTLSFLTSEIKSLFVHPFL ENSRNOP00000021321/1-1066 IEKDRGEWESLTPEARREKEAGLQMFGQLARFHNIMSNETIGTLSFLTSEIKSLFVHPFL XP_004856754.1/1-1066 IEKDRGEWDSLTPEARREKEAGLQMFGQLARFHNIMSNETIGTLAFLTSEIKSLFVHPFL ENSP00000387362/1-1073 IEKDRGEWDSLTPEARREKEAGLQMFGQLARFHNIMSNETIGTLAFLTSEIKSLFVHPFL ENSCPOP00000011851/1-1067 IEKDRGEWDNLSPEARREKEAGLQMFGQLARFHNIMSNETIGTLTFLTSEIKSLFVHPFL ********:.*:********************************:*************** ENSMUSP00000112632/1-1085 AERIISMLNYFLQHLVGPKMGALKVKDFSEFDFKPQQLVSDICTIYLNLGDEENFCATVP ENSRNOP00000021321/1-1066 AERIISMLNYFLQHLVGPKMGALKVKDFSEFDFKPQQLVSDICTIYLNLGDEENFCATVP XP_004856754.1/1-1066 AERIISMLNYFLQHLVGPKMGALKVKDFSEFDFKPQQLVSDICTIYLNLGDEENFCATVP ENSP00000387362/1-1073 AERIISMLNYFLQHLVGPKMGALKVKDFSEFDFKPQQLVSDICTIYLNLGDEENFCATVP ENSCPOP00000011851/1-1067 AERIISMLNYFLQHLVGPKMGALKVKDFSEFDFKPQQLVSDICTIYLNLGDEENFCATVP ************************************************************ ENSMUSP00000112632/1-1085 KDGRSYSPTLFAQTVRVLKKINKPGNMIVAFSNLAERIKSLADLQQQEEETYADACDEFL ENSRNOP00000021321/1-1066 KDGRSYSPTLFAQTVRVLKKINKPGNMIVAFSNLAERIKSLADLQQQEEETYADACDEFL XP_004856754.1/1-1066 KDGRSYSPTLFAQTVRVLKKINKPGNMIVAFSNLAERIKSLADLQQQEEETYADACDEFL ENSP00000387362/1-1073 KDGRSYSPTLFAQTVRVLKKINKPGNMIMAFSNLAERIKSLADLQQQEEETYADACDEFL ENSCPOP00000011851/1-1067 KDGRSYSPTLFAQTVRVLKKINKPGNMIVAFSNLAERIKSLADLQQQEEETYADACDEFL ****************************:******************************* ENSMUSP00000112632/1-1085 DPIMSTLMSDPVVLPSSRVTVDRSTIARHLLSDQTDPFNRSPLTMDQIRPNTELKEKIQR ENSRNOP00000021321/1-1066 DPIMSTLMSDPVVLPSSRVTVDRSTIARHLLSDQTDPFNRSPLTMDQIRPNTELKEKIQR XP_004856754.1/1-1066 DPIMSTLMSDPVVLPSSRVTVDRSTIARHLLSDQTDPFNRSPLTMDQIRPNTELKEKIQQ ENSP00000387362/1-1073 DPIMSTLMCDPVVLPSSRVTVDRSTIARHLLSDQTDPFNRSPLTMDQIRPNTELKEKIQR ENSCPOP00000011851/1-1067 DPIMSTLMSDPVVLPSSRVTVDRSTIARHLLSDQTDPFNRSPLTMDQIRPNTELKEKIQR ********.**************************************************: ENSMUSP00000112632/1-1085 WLAERKQQKEQPE ENSRNOP00000021321/1-1066 WLAERKQQKEQLE XP_004856754.1/1-1066 WLAERKQQKEQLE ENSP00000387362/1-1073 WLAERKQQKEQLE ENSCPOP00000011851/1-1067 WLAERKQQKEQLE *********** *