CLUSTAL W(1.81) multiple sequence alignment ENSMUSP00000072662/1-1374 MTDESSDVPRELMESIKDVIGRKIKISVKKKVKLEVKGDRVENKVLVLTSCRAFLLSARI ENSRNOP00000056268/1-1374 MTDESSDVPRELMESIKDVIGRKIKISVKKKVKLEVKGDRVENKVLVLTSCRAFLLSARI ENSP00000331983/1-1371 MTEESSDVPRELIESIKDVIGRKIKISVKKKVKLEVKGDKVENKVLVLTSCRAFLVTARI ENSCPOP00000011704/1-1373 MTEESADVPRELLESIKDVIGRKIKIAMKKKVKLEVKGDKVENKVLVLTSCRAFLVTARI XP_004847643.1/1-1373 MTEESADVPRELLESIKDVIGRKVKIAVKKKVKLEVKGDKVENKVLVLTSCRAFLVTARI **:**:******:**********:**::***********:***************::*** ENSMUSP00000072662/1-1374 PSKLELTFSYLEIHGVICHKPAQMVVETEKCNMSMKMVSPEDVSEVLAHIGTCLRRIFPG ENSRNOP00000056268/1-1374 PTKLELTFSYLEIHGVICHKPTQMVVETEKCNVSMKMASLEDASDVLAHIGTCLRRIFPG ENSP00000331983/1-1371 PTKLELTFSYLEIHGVVCSKSAQMIVETEKCSISMKMASPEDVSEVLAHIGTCLRKIFPG ENSCPOP00000011704/1-1373 PTKLELTFSYLEIHGVVCTRPAQMVVETEKCNISMKMAAPEDVSDVLGHIGTCLRKIFPG XP_004847643.1/1-1373 PTKLELTFSYLEIHGVVCTKPAQMVVETEKCNISMKMASPEDVSDVLGHIGTCLRKIFPG *:**************:* :.:**:******.:****.: **.*:**.*******:**** ENSMUSP00000072662/1-1374 LSPLRIMKKVSMEPSERLASLQALWDSQTLAEPGPCGGFSQMYACVCDWLGFSYKEEVQW ENSRNOP00000056268/1-1374 LSPLRIMKKVSMEPSERLASLQALWDSQTLAEPGPCGGFSQMYACVCDWLGFSYREEVQW ENSP00000331983/1-1371 LSPVRIMKKVSMEPSERLASLQALWDSQTVAEQGPCGGFSQMYACVCDWLGFSYREEVQW ENSCPOP00000011704/1-1373 LSPVRIMKKVSMEPSERLASLQALWDGQTVAEQGPCGGFSQMYACVCDWLGFSYREEVQW XP_004847643.1/1-1373 LSPVRIMKKVSMEPSERLASLQALWDSQTVAEQGPCGGFSHMYACVCDWLGFSYREEVQW ***:**********************.**:** *******:*************:***** ENSMUSP00000072662/1-1374 DVDTIYLTQDTRELNLQDFSHLEHRDLIPIIAALEYNQWFTKLSSKDLKLSTDVCEQILR ENSRNOP00000056268/1-1374 DVDTIYLTQDTRELNLQDFSHLEHRDLIPIIAALEYNQWFTKLSSKDLKLSTDVCEQILR ENSP00000331983/1-1371 DVDTIYLTQDTRELNLQDFSHLDHRDLIPIIAALEYNQWFTKLSSKDLKLSTDVCEQILR ENSCPOP00000011704/1-1373 DVDTIYLTQDTRELNLQDFSHLDHRDLIPIIAALEYNQWFTKLSSKDLKLSTDVCEQILR XP_004847643.1/1-1373 DVDTIYLTQDTRELNLQDFSHLDHRDLIPIIAALEYNQWFTKLSSKDLKLSADVCEQILR **********************:****************************:******** ENSMUSP00000072662/1-1374 VVSRSNRLEELVLENAGLRIDFAQKLAGALAHNPNSGLHTINLAGNSLEDRGVSSLSIQF ENSRNOP00000056268/1-1374 VVSRSNLLEELVLENAGLRTDFAQKLASALAHNPNSGLHTINLAGNPLEDRGVSSLSIQF ENSP00000331983/1-1371 VVSRSNRLEELVLENAGLRTDFAQKLASALAHNPNSGLHTINLAGNPLEDRGVSSLSIQF ENSCPOP00000011704/1-1373 VVSRSNRLEELVLENAGLRIDFAQKLAFALAHNPNSGLHTINLAGNPLEDRGVSSLSIQF XP_004847643.1/1-1373 VVSRSNRLEELVLENAGLRTDFTQKLAFALAHNPNSGLHTINLASNPLEDRGVSSLSIQF ****** ************ **:**** ****************.*.************* ENSMUSP00000072662/1-1374 AKLPKGLKHLNLSKTSLSPKGVNSLCQSLSANPLTASTLTHLDLSGNALRGDDLSHMYNF ENSRNOP00000056268/1-1374 AKLPKGLKHLNLSKTSLSPKGVNSLCQSLSANPLTASTLTHLDLSGNVLRGDDLSHMYNF ENSP00000331983/1-1371 AKLPKGLKHLNLSKTSLSPKGVNSLSQSLSANPLTASTLVHLDLSGNVLRGDDLSHMYNF ENSCPOP00000011704/1-1373 AKLPKGLKHLNLSKTSLSPKGVNSLSQSLSANPLTASTLTHLDLSGNVLRGDDLSHLYNF XP_004847643.1/1-1373 AKLPKGLKHLNLSKTSLSPKGVNSLSQSLSANPLTASTLTHLDLSGNVLRGDDLSHMYNF *************************.*************.*******.********:*** ENSMUSP00000072662/1-1374 LAQPNTIVHLDLSNTECSLEMVCSALLRGCLQCLAVLNLSRSVFSHRKGKEVPPSFKQFF ENSRNOP00000056268/1-1374 LAQPNTIVHLDLSNTECSLEMVCSALLRGCLQCLAVLNLSRSVFSHRKGKEVPPSFKQFF ENSP00000331983/1-1371 LAQPNAIVHLDLSNTECSLDMVCGALLRGCLQYLAVLNLSRTVFSHRKGKEVPPSFKQFF ENSCPOP00000011704/1-1373 LAQPNAIAYLDLSNTECSLDMVCGALLRGCLQYLAVLNLSRTVFSHRKGKEVPLSFKQFF XP_004847643.1/1-1373 LAQPNAIAYLDLSNTECSLDMVCGALLRGCLQYLAVLNLSRTVFSHRKGKEVPPSFKQFF *****:*.:**********:***.******** ********:*********** ****** ENSMUSP00000072662/1-1374 SSSLALIQINLSGTKLSPEPLKALLLGLACNHSLKGVSLDLSNCELGHCLRSGGAQVLEG ENSRNOP00000056268/1-1374 SSSLALIQINLSGTKLSPEPLKALLLGLACNHSLKGVSLDLSNCELGHCLRSGGAQVLEG ENSP00000331983/1-1371 SSSLALMHINLSGTKLSPEPLKALLLGLACNHNLKGVSLDLSNCE----LRSGGAQVLEG ENSCPOP00000011704/1-1373 SSSLALMQINLSGTKLSPEPLKALLLGLACNHNLKGVSLDLSNCE----LRSGGAQVLEG XP_004847643.1/1-1373 SSSLALMQINLSGTKLSPEPLKALLLGLACNHNLKGVSLDLSNCE----LRSGGAQVLEG ******::************************.************ *********** ENSMUSP00000072662/1-1374 CIAEIHNITSLDISDNGLESDLSTLIVWLSKNRSIQHLALGKNFNNMKSKNLTPVLDNLV ENSRNOP00000056268/1-1374 CIAEIHNITSLDISDNGLESDLSTLIVWLSRNRSIQHLALGKNFNNMKSKNLTPVLDNLV ENSP00000331983/1-1371 CIAEIHNITSLDISDNGLESDLSTLIVWLSKNRSIQHLALGKNFNNMKSKNLTPVLDNLV ENSCPOP00000011704/1-1373 CIAEIHNITSLDISDNGLESDLSTLIVWLSKNRSIQHLALGKNFNNMKSKNLTPVLDNLV XP_004847643.1/1-1373 CIAEIHNIASLDISDNGLESDLSTLIVWLSKNRSIQHLALGKNFNNMKSKNLTPVLDNLV ********:*********************:***************************** ENSMUSP00000072662/1-1374 QMIQDEDSPLQSLSLADSKLKAEVTIIINALGSNTSLTKVDISGNGMGDMGAKMLAKALQ ENSRNOP00000056268/1-1374 QMIQDEDSPLQSLSLADSKLKTEVTIIINALGSNTSLTKVDISGNSMGDMGAKMLAKALQ ENSP00000331983/1-1371 QMIQDEESPLQSLSLADSKLKTEVTIIINALGSNTSLTKVDISGNGMGDMGAKMLAKALQ ENSCPOP00000011704/1-1373 QMIQDEDSPLQSLSLADSKLKTEVTIIINALGSNTSLTKVDISGNGMGDMGAKMLAKALQ XP_004847643.1/1-1373 QMIQDEDSPLQSLSLADSKLKTEVTIIINALGSNTSLTKVDISGNGMGDMGAKMLAKALQ ******:**************:***********************.************** ENSMUSP00000072662/1-1374 INTKLRTVIWDKNNITAQGFQDIAVAMEKNYTLRFMPIPMYDAAQALKTNPEKTEEALQK ENSRNOP00000056268/1-1374 INTKLRTVIWDKNNITAQGFQDIAVAMEKNYTLRFMPIPMYDASQALKTSPEKTEEALQK ENSP00000331983/1-1371 INTKLRTVIWDKNNITAQGFQDIAVAMEKNYTLRFMPIPMYDASQALKTNPEKTEDALQK ENSCPOP00000011704/1-1373 INTKLRTVIWDKNNITAQGFQDIAVAMEKNYTLRFMPIPMYDASQALKTNPEKTEEALQK XP_004847643.1/1-1373 INTKLRTVIWDKNNITAQGFQDIAVAMEKNYTLRFMPIPMYDASQALKTNPEKTEEALQK *******************************************:*****.*****:**** ENSMUSP00000072662/1-1374 IENYLLRNHETRKYLQEQAYRLQQGIVTSTTQQMIDRICVKVQDHLNSLRACGGDAIQED ENSRNOP00000056268/1-1374 IENYLLRNHETRKYLQEQAYRLQQGIVTSTTQQMIDRICVKVQDHLNSLRACGGDAIQED ENSP00000331983/1-1371 IENYLLRNHETRKYLQEQAYRLQQGIVTSTTQQMIDRICVKVQDHLNSLRNCGGDAIQED ENSCPOP00000011704/1-1373 IENYLLRNHETRKYLQEQAYRLQQGIVTSTTQQMIDRICVKVQDHLNSLRNCGGDAIQED XP_004847643.1/1-1373 IENYLLRNHETRKYLQEQAYRLQQGIVTSTTQQMIDRICVKVQDHLNSLRNCGGDAIQED ************************************************** ********* ENSMUSP00000072662/1-1374 LKAAERLMRDAKNSKTLLPNLYHVGGASWAGASGLSSSPIQETLESMAGEVTRVVDEQLK ENSRNOP00000056268/1-1374 LKAAERLMRDAKNSKTLLPNLYHVGGASWAGASGLSSSPIQEILESMAGEVTRVVDEQLK ENSP00000331983/1-1371 LKSAERLMRDAKNSKTLLPNLYHVGGASWAGASGLLSSPIQETLESMAGEVTRVVDEQLK ENSCPOP00000011704/1-1373 LKSAERLMRDAKNSKTLLPNLYHVGGACWAGASGLLSSPIQETLESMAGEVTRVVDEQLK XP_004847643.1/1-1373 LKSAERLMRDAKNSKTLLPNLYHVGGVSWAGASGLLSNPIQETLESMAGEVTRVVDEQLK **:***********************..******* *.**** ***************** ENSMUSP00000072662/1-1374 DLLESMVDAAETLCPNVMRKAHIRQDLIHASTEKISIPRTFVKNVLLEQSGIDILNKISE ENSRNOP00000056268/1-1374 GLLESMVDAAENLCPNVMRKAHIRQDLIHASTEKISIPRTFVKNVLLEQSGIDILNKISE ENSP00000331983/1-1371 ALLESMVDAAENLCPNVMKKAHIRQDLIHASTEKISIPRTFVKNVLLEQSGIDILNKISE ENSCPOP00000011704/1-1373 ALLESMVDAAENLCPNVMKKAHIRQDLIHASTEKISIPRTFVKNVLLEQSGVDILNKISE XP_004847643.1/1-1373 ALLESMVDAAENLCPNVMRKAHIRQDLIHASTEKISVPRTFVKNVLLEQSGIDILNKISE **********.******:*****************:**************:******** ENSMUSP00000072662/1-1374 VKLTVASFLSDRIVDEILDSLSSSHRKLANHFSRLNKSLPQREDLEVELVEEKPVKRAIL ENSRNOP00000056268/1-1374 VKLTVASFLSDRIVDEILDSLSNSHRKLANHFSRLSKSLPQREDLEVELVEEKPVKRAIL ENSP00000331983/1-1371 VKLTVASFLSDRIVDEILDALSHCHHKLADHFSRRGKTLPQQESLEIELAEEKPVKRSII ENSCPOP00000011704/1-1373 VKLTVASFLSDRIVDEILDALSHCHHKLADHFNRRGKTLPQQDSLDIELAEEKPAKRSLI XP_004847643.1/1-1373 VKLTVASFLSDRIVDEILDALSHCHHKLAEHFSRRGKTLPQQESLEIELAEEKPAKLSLI *******************:** .*:***:**.* .*:***::.*::**.****.* ::: ENSMUSP00000072662/1-1374 TVEDLTEVERLEDLDTCMMTPKSKRKSIHSRMLRPVSRAFEMEFDLDKALEEVPIHIEDP ENSRNOP00000056268/1-1374 TVEDLTEVEKLEDLDTCMMTPKSKRKSIHSRMLRPVSRAFEMEFDLDKALEEVPIHIEDP ENSP00000331983/1-1371 TVEELTEIERLEDLDTCMMTPKSKRKSIHSRMLRPVSRAFEMEFDLDKALEEVPIHIEDP ENSCPOP00000011704/1-1373 TVEELTEVERLEDLDTCMMTPKSKRKSIHSRMLRPVSRAFEMEFDLDKALEEVPIHVEDP XP_004847643.1/1-1373 TLEELTEVERLEDLDTCMMTPKSKRKSIHSRMLRPVSRAFEMEFDLDKALEEVPIHVEDP *:*:***:*:**********************************************:*** ENSMUSP00000072662/1-1374 PFPSVRQEKRSSGLISELPSEEGRRLEHFTKLRPKRNKKQQPTQAAVCTISILPQDGEQN ENSRNOP00000056268/1-1374 PFPSVRQEKRSSGLISELPSEEGRRLEHFTKLRPKRNKKQQPTQAAVCSINIIPHDGEQN ENSP00000331983/1-1371 PFPSLRQEKRSSGFISELPSEEGKKLEHFTKLRPKRNKKQQPTQAAVCAANIVSQDGEQN ENSCPOP00000011704/1-1373 PFPSVRQEKRSSGFISELPSEEGRKLEHFTKLRPKRNKKQQPTQAAVCAAAIVSQDGEQN XP_004847643.1/1-1373 PFPSIKQEKRSSGFISELPSEEGRKLEHFTKLRPKRNKKQQPTQAAVCAAGIVSQDGEQN ****::*******:*********::***********************: *:.:***** ENSMUSP00000072662/1-1374 GLMGRVDEGVDEFFTKKVTKMDCKRSSSRSSDAHELGE-GDEKKKRDSRR-SGFLNLIKS ENSRNOP00000056268/1-1374 GLMGRVDEGVDEFFTKKVTKMDCKRSSTRCSDTHDLVE-GDEKKKRDSRR-SGFLNLIKS ENSP00000331983/1-1371 GLMGRVDEGVDEFFTKKVTKMDSKKWSTRGSESHELNEGGDEKKKRDSRKSSGFLNLIKS ENSCPOP00000011704/1-1373 GLMGRVDEGVDEFFTKKVTKMDSKRTSARGSESHELSEGGDEKKKRDSRK-SGFLNLIKS XP_004847643.1/1-1373 GLMGRVDEGVDEFFTKKVTKMDSKRTSSRGSESHELSEGGDEKKKRDSRK-SSFLNLIKS **********************.*: *:* *::*:* * **********: *.******* ENSMUSP00000072662/1-1374 RSRSERPPTVLMTEELSSPKGAMRSPPVDTTRKEIKAAEHNGAPDRTEEIKTPEPLEEGP ENSRNOP00000056268/1-1374 RSRSERPPTVLMTEELSSPKGAVRSPPVDTARKEIKAAEHNGAPERTEEMRTPEPLEEGL ENSP00000331983/1-1371 RSKSERPPTILMTEEPSSPKGAVRSPPVDCPRKDTKAAEHNGNSERIEEIKTPDSFEESQ ENSCPOP00000011704/1-1373 RSKCERPPTVLMTEEPSSPKGAVRGSAVDTPRKEPKATEHNGNSDRAEEIKTPDSIDESL XP_004847643.1/1-1373 RSKSERPPMVLMTEEPSSPKGAIRSSATDAPRREPKASEHDGNSDIAEEMKTPDSLEESP **:.**** :***** ******:*....* .*:: **:**:* .: **::**:.::*. ENSMUSP00000072662/1-1374 AEEAGRAERSDSRGSPQGGRRY-VQVMGSGLLAEMKAKQERRAACAQKKLGNDVISQDPS ENSRNOP00000056268/1-1374 AEEAGRAERSDSRGSPQGGRRY-VQVMGSGLLAEMKAKQERRAACAQKKLGNDVISQDPS ENSP00000331983/1-1371 GEEIGKVERSDSKSSPQAGRRYGVQVMGSGLLAEMKAKQEKRAACAQKKLGNDAVSQDSS ENSCPOP00000011704/1-1373 GEEAGHTERGDSRSSPQAGRRYGVQVMGSSLLAEMKAKQEQRAACAQKKLGNDAMSQDYP XP_004847643.1/1-1373 GEEVGRLERGDSRSSPQGGRRYGVQVMGSGLLAEMKAKQERRAASAQKKLGNDAISQDFP .** *: **.**:.***.**** ******.**********:***.********.:*** . ENSMUSP00000072662/1-1374 SPVSCNTERLEGGATVPKLQPGLPEARFGSGTPEKNAKAEPRVDGGCRSRSSSSMPTSPK ENSRNOP00000056268/1-1374 SPVMSNTERLDGGATVPKLQPGLPEARFGLGTPEKNAKAEPRVDGGCRSRNSSSMPTSPK ENSP00000331983/1-1371 SPALSGVERSDGGGAVPKLHPGLPENRFGLGTPEKNTKAEPKAEAGSRSRSSSSTPTSPK ENSCPOP00000011704/1-1373 SPTLSSVERLDGGGAVPKLHPGLPENRFGLGTPEKNAKAESKVEASSRSRSSSCTPTSPK XP_004847643.1/1-1373 SPALSSVERLDGGGAVPKLHPGLPENRFGLGTPEKNAKAEPKVEVVLRSRSSSSTPTSPK **. ...** :**.:****:***** *** ******:***.:.: ***.**. ***** ENSMUSP00000072662/1-1374 PLLQSPKPSPSARPSIPQKPRTASRPEDTPDSPSGPSSPKVALLPPILKKVSSDKERDGQ ENSRNOP00000056268/1-1374 PLLQSPKPSPAARPSIPQKPRTASKPEDTPDSPSGPSSPKVALLPPILKKVSLDKERDDQ ENSP00000331983/1-1371 PLLQSPKPSLAARPVIPQKPRTASRPDDIPDS---PSSPKVALLPPVLKKVPSDKERDGQ ENSCPOP00000011704/1-1373 PLLQSPKPTLAARPTIPQKPRTASRPEDVPDSPSGPSSPKVALLPPVLKKVPSDKERDGQ XP_004847643.1/1-1373 PLLQSPKPTLAARPTIPQKPRTASRPEDVPDSPSGPSSPKVALLPPILKKVPSDKERDAQ ********: :*** *********:*:* *** ***********:****. ***** * ENSMUSP00000072662/1-1374 NSSQSSPRSFSQEASRRSWGP-AQEYQEQKQRSSGKDGHQGSKCSDSGEEAEKEFIFV ENSRNOP00000056268/1-1374 SSSQSSPRTFSQEVSRRSWGP-AQEYQEQKQRNLGKDGHQGSKSSDSGEEAEKEFIFV ENSP00000331983/1-1371 SSPQPSPRTFSQEVSRRSWGQQAQEYQEQKQRSSSKDGHQGSKSNDSGEEAEKEFIFV ENSCPOP00000011704/1-1373 NSPQPSPRTYSQEVSRRSWGQQAQEYQEQRQQSSSKDGFQGSKSSDSGEEAEKEFIFV XP_004847643.1/1-1373 NNPQPSPRTYSQEVSRRSWGPQAQDYQEQKQQSSNKDSLQGSKSSDSGEEAEKEFIFV ...*.***::***.****** **:****:*:. .**. ****..*************