CLUSTAL W(1.81) multiple sequence alignment ENSCPOP00000011030/1-723 -----------------------------------ALAANAGTGFAVAEPQIAMFCGKLN XP_004862691.1/1-714 MAATATAAVAATGRLLILLLLGLTAPAAALAGYIEALAANAGTGFAVAEPQIAMFCGKLN ENSP00000263574/1-763 MAATGTAAAAATGRLLLLLLVGLTAPALALAGYIEALAANAGTGFAVAEPQIAMFCGKLN ENSMUSP00000072428/1-751 MAATGTAAAAATGKLLVLLLLGLTAPAAALAGYIEALAANAGTGFAVAEPQIAMFCGKLN ENSRNOP00000067835/1-733 --------------------------------YMEALAANAGTGFAVAEPQIAMFCGKLN ************************* ENSCPOP00000011030/1-723 MHVNIQTGKWEPDPTGTKSCFGTKEKVLQYCQEIYPELQITNVMEANQPVNVDNWCRRDK XP_004862691.1/1-714 MHVNIQTGKWEPDPTGMKSCFGTKEEVLQYCQEMYPELQITNVMEANQPVSIDNWCRRDK ENSP00000263574/1-763 MHVNIQTGKWEPDPTGTKSCFETKEEVLQYCQEMYPELQITNVMEANQRVSIDNWCRRDK ENSMUSP00000072428/1-751 MHVNIQTGKWEPDPTGTKSCLGTKEEVLQYCQEIYPELQITNVMEANQPVNIDSWCRRDK ENSRNOP00000067835/1-733 MHVNIQTGKWEPDPTGTKSCLGTKEEVLQYCQEIYPELQITNVMEANQPVNIDSWCRRDK **************** ***: ***:*******:************** *.:*.****** ENSCPOP00000011030/1-723 KQCKSHAVIPFKCLVGEFVSDVLLVPEKCQFFHRERMEVCENHQHWHTEVREACLTQGMT XP_004862691.1/1-714 KQCKNHIVIPFKCLVGEFVSDVLLVPEKCQFFHRERMEICENHQHWHTEVKEACLTQGMT ENSP00000263574/1-763 KQCKSRFVTPFKCLVGEFVSDVLLVPEKCQFFHKERMEVCENHQHWHTVVKEACLTQGMT ENSMUSP00000072428/1-751 RQCKSHIVIPFKCLVGEFVSDVLLVPDNCQFFHQERMEVCEKHQRWHTLVKEACLTEGLT ENSRNOP00000067835/1-733 KQCRSHIVIPFKCLVGEFVSDVLLVPENCQFFHQERMEVCEKHQRWHTVVKEACLTEGMT :**:.: * *****************::*****:****:**:**:*** *:*****:*:* ENSCPOP00000011030/1-723 LYSYGMLLPCGVDQFHGTEYVCCPPVKFSDSSDSLVSKEDQEEDE-----DEDEEEDYDI XP_004862691.1/1-714 LYSYGMLLPCGVDQFHGTEYVCCPPTKISESSDSTMSKEEQEEDEDDDNDDEDEEEDYDI ENSP00000263574/1-763 LYSYGMLLPCGVDQFHGTEYVCCPQTKIIG----SVSKEEEEEDEEEE-EEEDEEEDYDV ENSMUSP00000072428/1-751 LYSYGMLLPCGVDQFHGTEYVCCPQTKTVD-SDSTMSKEEEEEEE----DEEDEEEDYDL ENSRNOP00000067835/1-733 LYSYGMLLPCGVDQFHGTEYVCCPQTKVVD-SDSTMSKEEEEEEE------EDEEEDYAL ************************ .* :***::**:* ******* : ENSCPOP00000011030/1-723 YKSEFPTEPDLEDFTEAAV---DEDEDADAEAGEEVVEDRDYYYDSFKGDDYNEETPTEP XP_004862691.1/1-714 YKSEFPTEPDLEDFTEAAV--DEENEDEDEEEGEEVVEDRDYYYDTFKGDDYNDENPTEP ENSP00000263574/1-763 YKSEFPTEADLEDFTEAAV----DEDDEDEEEGEEVVEDRDYYYDTFKGDDYNEENPTEP ENSMUSP00000072428/1-751 DKSEFPTEADLEDFTEAAA----DEEEEDEEEGEEVVEDRDYYYDPFKGDDYNEENPTEP ENSRNOP00000067835/1-733 DKSEFPTEADLEDFTEAAADEDEDEEEEEEEEGEEVVEDRDYYYDSFKGDDYNEENPTEP *******.*********. :::: : * *************.*******:*.**** ENSCPOP00000011030/1-723 SHVGAVADQETTRDVKAVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFE XP_004862691.1/1-714 SSNGAISDKEIAHDVK-------------------------------------------- ENSP00000263574/1-763 GSDGTMSDKEITHDVKAVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFE ENSMUSP00000072428/1-751 SSEGTISDKEIVHDVKAVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFE ENSRNOP00000067835/1-733 SSDGTISDKEIAHDVKAVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFE . *:::*:* .:*** ENSCPOP00000011030/1-723 SEDYCLAVCKAMIPPTPLPTNDVDVYFETAADDNEHARFQKAKEQLEIRHRNRMDRVKKE XP_004862691.1/1-714 ------------VPPTPLPTNDVDVYFETAADDNEHARFQKAKEQLEIRHRNRMDRVKKE ENSP00000263574/1-763 SEDYCMAVCKAMIPPTPLPTNDVDVYFETSADDNEHARFQKAKEQLEIRHRNRMDRVKKE ENSMUSP00000072428/1-751 SEDYCMAVCKAMIPPTPLPTNDVDVYFETSADDNEHARFQKAKEQLEIRHRNRMDRVKKE ENSRNOP00000067835/1-733 SEDYCMAVCKTMIPPTPLPTNDVDVYFETSADDNEHARFQKAKEQLEIRHRSRMDRVKKE :****************:*********************.******** ENSCPOP00000011030/1-723 WEEAELQAKNLPKAERQTLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRMA XP_004862691.1/1-714 WEEAELQAKNLPKAERQTLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRMA ENSP00000263574/1-763 WEEAELQAKNLPKAERQTLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRMA ENSMUSP00000072428/1-751 WEEAELQAKNLPKTERQTLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRIA ENSRNOP00000067835/1-733 WEEAELQAKNLPKAERQTLIQHFQAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRIA *************:********************************************:* ENSCPOP00000011030/1-723 LENYLAALQSDPPRPHRILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQLVQ XP_004862691.1/1-714 LENYLAALQSDPPKPHRILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMT ENSP00000263574/1-763 LENYLAALQSDPPRPHRILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMT ENSMUSP00000072428/1-751 LENYLAALQSDPPRPHRILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMT ENSRNOP00000067835/1-733 LENYLAALQSDPPRPHRILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMT *************:*******************************************:: ENSCPOP00000011030/1-723 IICLLRFWNNRQLS---SAPFVAQR---NLYELLQEQRADMDQFTASISESPVDVRVSSE XP_004862691.1/1-714 HLHVIEERRNQSLSLLYKVPYVAQEIQVEIDELLQEQRADMDQFTASISEIPMDVRVSSE ENSP00000263574/1-763 HLHVIEERRNQSLSLLYKVPYVAQEIQEEIDELLQEQRADMDQFTASISETPVDVRVSSE ENSMUSP00000072428/1-751 HLHVIEERRNQSLSLLYKVPYVAQEIQEEIDELLQEQRADMDQFTSSISENPVDVRVSSE ENSRNOP00000067835/1-733 HLHVIEERRNQSLSLLYKVPYVAQEIQEEIDELLQEQRADMDQFTSSISENPVDVRVSSE : ::. .*:.** ..*:***. :: **************:**** *:******* ENSCPOP00000011030/1-723 ESEEFPPFHSFHPFPPLPENEDTPPELFHPVKKGSGVGEQDRGLIGAEEKLINSKNKVDE XP_004862691.1/1-714 ESEEFPPFHSIHPFPPLPENEDTQPELYHPVKKGSGVGEQDQGLIGAEEKVINSKNKVDE ENSP00000263574/1-763 ESEEIPPFHPFHPFPALPENEDTQPELYHPMKKGSGVGEQDGGLIGAEEKVINSKNKVDE ENSMUSP00000072428/1-751 ESEEIPPFHPLHPFPSLSENE------------GSGMAEQDGGLIGAEEKVINSKNKMDE ENSRNOP00000067835/1-733 ESEEIPPFHPFHPFPSLSENEDTQPELYHPMKKGSGMAEQDGGLIGAEEKVINSKNKMDE ****:****.:****.*.*** ***:.*** ********:******:** ENSCPOP00000011030/1-723 NMVVDETLDVKEMIFNAERVGGLEGEPESVRPVREDFSLSSSALIGLLVIAVAIATVIVI XP_004862691.1/1-714 NMVIDETLDVKEMIFNAERVGGLEEEPESVRPLREDFSLSSSALIGLLVIAVAIATVIVI ENSP00000263574/1-763 NMVIDETLDVKEMIFNAERVGGLEEERESVGPLREDFSLSSSALIGLLVIAVAIATVIVI ENSMUSP00000072428/1-751 NMVIDETLDVKEMIFNAERVGGLEEEPESVGPLREDFSLSSNALIGLLVIAVAIATVIVI ENSRNOP00000067835/1-733 NMVIDETLDVKEMIFNAERVGGLEEEPDSVGPLREDFSLSSSALIGLLVIAVAIATVIVI ***:******************** * :** *:********.****************** ENSCPOP00000011030/1-723 SLVMLRKRQYGTISHGIVEVDPMLTPEERHLNKMQNHGYENPTYKYLEQMQI XP_004862691.1/1-714 SLVLLRKRQYGTISHGIVEVDPMLTPEERHLNKMQNHGYENPTYKYLEQMQI ENSP00000263574/1-763 SLVMLRKRQYGTISHGIVEVDPMLTPEERHLNKMQNHGYENPTYKYLEQMQI ENSMUSP00000072428/1-751 SLVMLRKRQYGTISHGIVEVDPMLTPEERHLNKMQNHGYENPTYKYLEQMQI ENSRNOP00000067835/1-733 SLVMLRKRQYGTISHGIVEVDPMLTPEERHLNKMQNHGYENPTYKYLEQMQI ***:************************************************