CLUSTAL W(1.81) multiple sequence alignment ENSP00000444425/1-906 MEKLLRLCCWYSWLLLFYYNFQVRGVYSRSQDHPGFQVLASASHYWPLENVDGIHELQDT ENSMUSP00000060307/1-903 MKDLPAFPCSWVWLLWSFCSVQVCSTQPRAQEHPGFAVLASASHYWPLENVDGILELQDT ENSRNOP00000055384/1-903 MKELPALSCHWVWLFWSFCGFQVCGTQPRAQEHPGFEVLASASHYWPLENVEGIRELQDT ENSCPOP00000010974/1-871 ---------------------------------PEFSVLASVSHYWPLESVDGIHELQDV XP_004844058.1/1-871 MRVRGPLRCRDLWLLLLCCTCQVRGAHPRAQDHPGFAVLASASHYWPLEDVDGIQELQDM * * ****.*******.*:** **** ENSP00000444425/1-906 TGASRTHKLTVLPSRNATFVYSNDSAYSNLSATVDIVEGKVNKGIYLKEEKGVTLLYYGR ENSMUSP00000060307/1-903 TGALRTLNLTVPLSHNATFVFTNDSAYSNLSATVDIMEGKVNKGIYLKEEKGVTFLYYGT ENSRNOP00000055384/1-903 TGALRTLNLTVPLSHNATFVFTNDSAYSNLSATVDIMEGKVNKSIYLKEEKGVTFLYYGR ENSCPOP00000010974/1-871 AAALRAHNLTVPLPHTSTFVPTRDSAYSNLSATVDLMEAKVNKSIYLREEKGVTLLLYN- XP_004844058.1/1-871 TG--------------------------------DLMEAKINKSIYLKEEKGETLLFYK- :. *::*.*:**.***:**** *:* * ENSP00000444425/1-906 YNSSCISKPEQCGPEGVTFSFFWKTQGEQSRPIPSAYGGQVISNGFKVCSSGGRGSVELY ENSMUSP00000060307/1-903 YKSSCISNPAQCGPEGVTFSFFWKTQGDQTRPAPYAYGGQVVSDGFKVCSSGGKGSVELY ENSRNOP00000055384/1-903 YKSSCISNPAQCGPEGVSFSFFWKTQGEQTRPAPYAYGGQVVSDGFKVCFSGGKGSVELY ENSCPOP00000010974/1-871 -SSSCISSPARCGPTGVTFSFFWKIQGEQSRPAPSTYGGQVISDGFKVCSSGSRGSVELY XP_004844058.1/1-871 -STSCISSPERCSVQGLTFSFFWKTQGEHARPAPSTYGGQVLSDSFKVCFSGSRGSVQLC .:****.* :*. *::****** **:::** * :*****:*:.**** **.:***:* ENSP00000444425/1-906 TRDNSMTWEASFSPPGPYWTHVLFTWKSKEGLKVYVNGTLSTSDPSGKVSRDYGESNVNL ENSMUSP00000060307/1-903 TRDNSMTWKATFNPPGPYWTHVLFTWKSKEGLKVYVNGTLSTSDPSGKVSHTYGDPHVNL ENSRNOP00000055384/1-903 TRDNSMTWKATFNPPGPYWTHVLFTWKSKEGLKVYVNGTLSTSDPSGKVSHAYGDPHINL ENSCPOP00000010974/1-871 TRDDFMTWEAAFSPLGPYWTHVLFTWKSKEGLKVYVNGTLSTWDSRGRVSRDYGEPSTNL XP_004844058.1/1-871 TRDDFMIWQATFSPLGPYWTHILFTWKSKEGLKVYVNGTLSTSDPSGKVSHDYGEPNANL ***: * *:*:*.* ******:******************** *. *:**: **:. ** ENSP00000444425/1-906 VIGSEQDQAKCYENGAFDEFIIWERALTPDEIAMYFTAAIGKHALLSSTLPSLFMTSTAS ENSMUSP00000060307/1-903 VIGSEQDQTKRYENGAFDEFIIWERALTPDEIKMYFTAAIGKHALLSSTPPA---MPTAH ENSRNOP00000055384/1-903 VIGCEHDWTKRYENGAFDEFIIWERALTPYEIKMYFTAAVGKYPPLSSTPPA---MPTAH ENSCPOP00000010974/1-871 VIGSEQDRTQCYENGAFDEFIFWERALNPAEIRMYFTAAVGKHGLPSSTPLPSVTMLTAI XP_004844058.1/1-871 VIGSEQDQTKCYEDGAFDEFIFWERALTPAEVRMYFSAAVGKHGLLSSTPPS-FVTRTAS ***.*:* :: **:*******:*****.* *: ***:**:**: *** . ** ENSP00000444425/1-906 PVMPTDAYHPIITNLTEERKTFQSPGVILSYLQNVSLSLPSKSLSEQTALNLTKTFLKAV ENSMUSP00000060307/1-903 TVIPTDAYHPIITNLTEERKRFQRPGTVLRYLQNVSLRLPNKSLSEETALNLTETFLRTV ENSRNOP00000055384/1-903 PVMPTDAYHPIITNLTEERKHFQRPRTVLRYLQNVSLSLPNKSLSEETALNLTETFLRTV ENSCPOP00000010974/1-871 ATVPRDAYHPIIANLTEERKNFSRPHVALSYLRSMSLSLPNKSLSEETALNLTETFLWTV XP_004844058.1/1-871 TMAPVDAYHPIITNLTEERQSFPRARTALNYLQNVTLSLPNKPLSEETALNLTETFLWAV . * *******:******: * . . * **:.::* **.*.***:******:*** :* ENSP00000444425/1-906 GEILLLPGWIALSEDSAVVLSLIDTIDTVMGHVSSNLHGSTPQVTVEGSSAMAEFSVAKI ENSMUSP00000060307/1-903 GEVLLLPSWTHESEDNAMTLGLVDTIDTVMGHISSNLQSREPHVTLTGSSSTAEFTVAKV ENSRNOP00000055384/1-903 GEVLLLPSWIHVSEDNAVTLGLVDTIDTVMGHISSNLQPREPHISLTGSSSMAEFSVAKV ENSCPOP00000010974/1-871 GEVLLLPGWKAASEDKALVSGLINTIDVVLGHVSLKLHGRRPEITLEGSSPVADFSVTKL XP_004844058.1/1-871 GQVLLPPSWTMALEDKALVPDLLDTIDTVMAHVSFNLQGGRLQVTLAGSSPVADFSLARL *::** *.* **.*:. .*::***.*:.*:* :*: .::: ***. *:*::::: ENSP00000444425/1-906 LPKTVNSSHYRFPAHGQSFIQIPHEAFHRHAWSTVVGLLYHSMHYYLNNIWPAHTKIAEA ENSMUSP00000060307/1-903 LPPALSAPHYRFPAHGHSYIEIPREALHSQAWTTIVGLLYHTMHYYLKNIHPTSTEIPEA ENSRNOP00000055384/1-903 LPPALSAPHYRFPAHGHSYIEIPREALHSQAWTTIVGLLYHTMHYYLNNIPPASTEIPEA ENSCPOP00000010974/1-871 LPRSLSTAYYRFPAHGDSYIEIPGEALRGPAWTTLVGLSYHSIHNFVSSIPPASTKIPVA XP_004844058.1/1-871 TPGTLSAAHYRFPAHGDSYIKIPGEALRGQAWTTIVGLLYHSVHQYVGNIPLASTTIPML * ::.:.:*******.*:*:** **:: **:*:*** **::* :: .* : * *. ENSP00000444425/1-906 MHHQDCLLFATSHLISLEVSPPPTLSQNLSGSPLITVHLKHRLTRKQHSEATNSSNRVFV ENSMUSP00000060307/1-903 VNCRDCLLSVASHLISLEVSPPPTLSQNLSGSPLITVHLRHKLTQKQYSDATNESNRLFL ENSRNOP00000055384/1-903 ANCRDCLLSVASHLISLEVSPPPTLSQNLSGSPLITVHLRHKLTQKQYVDATNESNRLFL ENSCPOP00000010974/1-871 ASCRDGLLFAVSPLISLEVRPPPALSQNLSRSPLVTVHLRHTLTQKQHSDATNASNRVFL XP_004844058.1/1-871 ASCRDGLLSTASPLISLEVRPPPALSRNLSGSPLVTVQLRHSLTGKQHIDATNGSNHVFL :* ** ..* ****** ***:**:*** ***:**:*:* ** **: :*** **::*: ENSP00000444425/1-906 YCAFLDFSSGEGVWSNHGCALTRGNLTYSVCRCTHLTNFAILMQVVPLELARGHQVALSS ENSMUSP00000060307/1-903 YCAFLNFSSGEGVWSSQGCALTEGNLTYSVCHCTHLTNFAILMQVVPLKLTHGHQVALSS ENSRNOP00000055384/1-903 YCAFLNFSSGEGVWSSQGCALTEGNLTYSVCHCTHLTNFAILMQVVPLKLTLGHQVALSS ENSCPOP00000010974/1-871 YCAFLDFSSGKGVWSSQGCALRDGNLTHSTCRCTHLTNFAILMQVVPLELPYGHQVALSS XP_004844058.1/1-871 YCAFLDFSSGQGVWSSRGCARVEGNLTYSVCRCTHLTNFAILMQVVPLELPRGHQVALSS *****:****:****.:*** ****:*.*:****************:*. ******** ENSP00000444425/1-906 ISYVGCSLSVLCLVATLVTFAVLSSVSTIRNQRYHIHANLSFAVLVAQVLLLISFRLEPG ENSMUSP00000060307/1-903 ISYVGCSLSVLCLAATLVTFAVLSSVSTIRNQRYHIHANLSFAVLVAQVLLLISFSMEPG ENSRNOP00000055384/1-903 ISYVGCSLSVLCLAATLVTFAVLSSVSTIRNQRYHIHANLSFAVLVAQVLLLISFSMEPG ENSCPOP00000010974/1-871 ISYVGCALSVLCLAATLVTFAVLSSVSTIRNQRYHIHANLSCAVLVAQVLLLGSFHVEPG XP_004844058.1/1-871 ISYVGCTLSVLCLAATLVTFAVLSSVSTIRNQRYHIHANLSCAVLVAQVLLLVSFHAEPG ******:******.*************************** ********** ** *** ENSP00000444425/1-906 TTPCQVMAVLLHYFFLSAFAWMLVEGLHLYSMVIKVFGSEDSKHRYYYGMGWGFPLLICI ENSMUSP00000060307/1-903 TVPCQVLAVLLHYFFLTAFAWMLVEGLHLYSMVIKVFGSEDSKHLYYYGIGWGCPLLICI ENSRNOP00000055384/1-903 TVPCQVLAVLLHYFFLTAFAWMLVEGLHLYSMVIKVFGSEDSKHLYYYGIGWGCPLLICI ENSCPOP00000010974/1-871 TVPCQVLATLLHYFFLSAFAWMLVEGLHLYSMVVKVFGSEGSKRLYYYGIGWGLPLVICV XP_004844058.1/1-871 TVPCQVLATLLHYFFLSTFAWMLVEGLHLYSLVIKVFGSEGSKHLYYYGIGWGLPLVICV *.****:*.*******::*************:*:******.**: ****:*** **:**: ENSP00000444425/1-906 ISLSFAMDSYGTSNNCWLSLASGAIWAFVAPALFVIVVNIGILIAVTRVISQISADNYKI ENSMUSP00000060307/1-903 ISISSSMDSYGTSDSCWLALGSGAIWAFVGPALLVIVVNIVILVAVTRVISHISTDSYKI ENSRNOP00000055384/1-903 ISVSSSMDSYGTGDSCWLSVESGAIWAFVGPALLVIVVNIVILVAVTRVISHISTDSYKI ENSCPOP00000010974/1-871 VSISFAMDSYGTSNNCWLSLGTGAIWAFVGPALLVIVVNIGILIAVTRVISQISADSYKI XP_004844058.1/1-871 VSISFAMDSYGTSDNCWLSLGTGAIWAFVGPALLVIVVNVGILIVVTRVISQISADSCKI :*:* :******.:.***:: :*******.***:*****: **:.******:**:*. ** ENSP00000444425/1-906 HGDPSAFKLTAKAVAVLLPILGTSWVFGVLAVNGCAVVFQYMFATLNSLQGLFIFLFHCL ENSMUSP00000060307/1-903 HGDPSAFKLTAKAVAVLLPILGTSWVFGVLAVSDRALVFQYMFAILNSLQGLFIFLFHCL ENSRNOP00000055384/1-903 HGDPSAFKLTAKAVAVLLPILGTSWVFGVLAVSDRALVFQYMFAILNSSQGLFIFLFHCL ENSCPOP00000010974/1-871 HGDPSAFKLTVKAVAVLLPILGTSWAFGVLAVNDQALVFQYMFAVLNSLQGGFIFLFHCL XP_004844058.1/1-871 HGDPSTFKLTAKAVAVLLPILGTSWAFGVLAVNGQALVFQYMFAVLNSLQGGFIFLFHCL *****:****.**************.******.. *:******* *** ** ******** ENSP00000444425/1-906 LNSEVRAAFKHKTKVWSLTSSSARTSNAKPFHSDLMNGTRPGMASTKLSPWDKSSHSAHR ENSMUSP00000060307/1-903 LNSEVRAAFKHKTKVWSLTSSSARTANTKPFSSDTVNGTRPGTASTKLSPWDKSSHSAHR ENSRNOP00000055384/1-903 LNSEVRAAFKHKMKVWSLTSSSAHTANTKPSSSDTVNGTRPGTASTKLSPWDKSSHSAHR ENSCPOP00000010974/1-871 LNSEVRAAFKHKTKVWSLTSSSARNASGKPFSSDMMNGTRPGTASTRPSPWDRSSHSAQR XP_004844058.1/1-871 LNSEVRAAFKHKTKVWSLSSSSARNVARKPLSSDTMNGTHLGSASTRLGPWDKSSHSAQR ************ *****:****:. ** ** :***: * ***: .***:*****:* ENSP00000444425/1-906 VDLSAV ENSMUSP00000060307/1-903 VDLSAV ENSRNOP00000055384/1-903 VDLSAV ENSCPOP00000010974/1-871 VDLSAV XP_004844058.1/1-871 VDLSSV ****:*