CLUSTAL W(1.81) multiple sequence alignment ENSCPOP00000010958/1-1459 ------------------------------------------------------------ ENSP00000301180/1-1576 MAERGLEPSPAAVAALPPEVRAQLAELELELSEGDITQKGYEKKRSKLLSPYSPQTQETD XP_004863038.1/1-1503 MAERGLEPSPAAVAALPPEVRAQLAELELELSEGDITQKGYEKKRSKLLSPYSPQTQETD ENSMUSP00000097777/1-1574 MAERGLEPSPAAVAALPPEVRAQLAELELELSEGDITQKGYEKKRSKLLSPYSPQTQETD ENSRNOP00000026289/1-1517 ---------------------------------------------------------ETD ENSCPOP00000010958/1-1459 ---------------------------------------SDIHTEAVQAALAKHKEQKMA ENSP00000301180/1-1576 SAVQKELRNQTPAPSAAQTSAPSKYHRTRSGGARDERYRSDIHTEAVQAALAKHKEQKMA XP_004863038.1/1-1503 SAVQKEHRNQTPAPAAAQTSAPSKYHRTRSGGARDERYRSDIHTEAVQAALAKHKEQKMA ENSMUSP00000097777/1-1574 SIGQKE-RNQTPAPTAAQTSAPSKYHRSRSGGARDERYRSDIHTEAVQAALAKHKEQKMA ENSRNOP00000026289/1-1517 STGQKE-RNQTPAPTAAQTSAPSKYHRSRSGGARDERYRSDIHTEAVQAALAKHKEQKMA ********************* ENSCPOP00000010958/1-1459 LPMPTKRRSTFVQSPAEACTPPDTSSASEDEGSLRRQAALSAALQQSLQNAESWINRSIQ ENSP00000301180/1-1576 LPMPTKRRSTFVQSPADACTPPDTSSASEDEGSLRRQAALSAALQQSLQNAESWINRSIQ XP_004863038.1/1-1503 LPMPTKRRSTFVQSPADACTPP-------------------------------------- ENSMUSP00000097777/1-1574 LPMPTKRRSTFVQSPADACTPPDTSSASEDEGSLRRQAALSAALQQSLQNAESWINRSIQ ENSRNOP00000026289/1-1517 LPMPTKRRSTFVQSPADACTPPDTSSASEDEGSLRRQAALSAALQQSLQNAESWINRSIQ ****************:***** ENSCPOP00000010958/1-1459 GSSTSSSASSTLSHGEVKGTSGSLADVFANTRIESFSAPPDVTTTT-SSSSSSSVRPANI ENSP00000301180/1-1576 GSSTSSSASSTLSHGEVKGTSGSLADVFANTRIENFSAPPDVTTTTSSSSSSSSIRPANI XP_004863038.1/1-1503 ---------------------------------ENFSAPPDVTTTT--SSSSSSVRPANI ENSMUSP00000097777/1-1574 GSSTSSSASSTLSHGEVKGTSGSLADVFANTRIENVSAPPDVTATT--SSSSSSLRPANI ENSRNOP00000026289/1-1517 GSSTSSSASSTLSHGEVKGTSGSLADVFANTRIENVSAPPDVTATT--SSSSSLLRPANI *..*******:** ***** :***** ENSCPOP00000010958/1-1459 DLPPSGIVKGMHKGANRSSLMDTADGVPVNSRVSTKIQQLLNTLKRPKRPPLKEFFVDDS ENSP00000301180/1-1576 DLPPSGIVKGMHKGSNRSSLMDTADGVPVSSRVSTKIQQLLNTLKRPKRPPLKEFFVDDS XP_004863038.1/1-1503 DLPPSGIVKGMHKGSNRSSLMDTADGVPVNSRVSTKIQQLLNTLKRPKRPPLKEFFVDDS ENSMUSP00000097777/1-1574 DLPPSGIVKGMHKGSNRSSLMDTADGVPVNSRVSTKIQQLLNTLKRPKRPPLKEFFVDDS ENSRNOP00000026289/1-1517 DLPPSGIVKGMHKGSNRSSLMDTADGVPVNSRVSTKIQQLLNTLKRPKRPPLKEFFVDDS **************:**************.****************************** ENSCPOP00000010958/1-1459 EEIVEVIVPQPDPNQPKPEGRQMTPVKGEPLGVICNWPPALESALQRWGSTQAKCPCLTA ENSP00000301180/1-1576 EEIVEV--PQPDPNQPKPEGRQMTPVKGEPLGVICNWPPALESALQRWGTTQAKCSCLTA XP_004863038.1/1-1503 EEIVEV--PQPDPNQPKPEGRQMTPVKGEPLGVICNWPPALESALQRWGATQAKCPCLTA ENSMUSP00000097777/1-1574 EEIVEGI-PQPDPNQPKPEGRQMTPVKGEPLGVICNWPPALESALQRWGSTQAKCPCLTG ENSRNOP00000026289/1-1517 EEIVEGI-PQPDPNQPKPEGRQMTPVKGEPLGVICNWPPALESALQRWGTTQAKCPCLTG ***** *****************************************:*****.***. ENSCPOP00000010958/1-1459 LDVTGKPVYTLTYAGKLWSRSLKLAYTLLNKLGTKNEPVLKPGDRVALVYPNNDPVMFMV ENSP00000301180/1-1576 LDMTGKPVYTLTY-GKLWSRSLKLAYTLLNKLGTKNEPVLKPGDRVALVYPNNDPVMFMV XP_004863038.1/1-1503 LDVTGKPVYTLTY-GKLWSRSLKLAYTLLNKLGTKNEPVLKPGDRVALVYPNNDPVMFMV ENSMUSP00000097777/1-1574 LDVTGKPVYTLTY-GKLWSRSLKLAYTLLNKLGTKNEPVLKPGDRVALVYPNNDPVMFMV ENSRNOP00000026289/1-1517 LDVTGKPVYTLTY-GKLWSRSLKLAYTLLNKLGTKNEPVLKPGDRVALVYPNNDPVMFMV **:********** ********************************************** ENSCPOP00000010958/1-1459 AFYGCLLAEVIPVPIEVPLTRKEGGALQQSYL---SIISIHKESCSCFRGLYKGMSFNHV ENSP00000301180/1-1576 AFYGCLLAEVIPVPIEVPLTRKDAGGQQIGFLLGSCGIALALTSEVCLKGLPKTQNGEIV XP_004863038.1/1-1503 AFYGCLLAEVIPVPIEVPLTRKDAGGQQIGFLLGSCGIALALTSEVCLKGLPKTQNGEIV ENSMUSP00000097777/1-1574 AFYGCLLAEVIPVPIEVPLTRKDAGGQQIGFLLGSCGIALALTSEICLKGLPKTQNGEIV ENSRNOP00000026289/1-1517 AFYGCLLAEVIPVPIEVPLTRKDAGGQQIGFLLGSCGIALALTSEICLKGLPKTQNGEIV **********************:.*. * .:* . *:: * *::** * . : * ENSCPOP00000010958/1-1459 TF-----YFWILILSSKLTHF--------------VTFLKYKTSKEGSVMGVTVSRLAML ENSP00000301180/1-1576 QFKGWPRLKWVVTDSKYLSKPPKDWQPHISPAGTEPAYIEYKTSKEGSVMGVTVSRLAML XP_004863038.1/1-1503 QFKGWPRLKWVVTDSKYLSKPPKDWQPHIPPAGTEPAYIEYKTSKEGSVMGVTVSRLAML ENSMUSP00000097777/1-1574 QFKGWPRLKWVVTDSKYLSKPPKDWQPHISPAGTEPAYIEYKTSKEGSVMGVTVSRLAML ENSRNOP00000026289/1-1517 QFKGWPRLKWVVTDSKYLSKPPKDWQPHISPAGTEPAYIEYKTSKEGSVMGVTVSRLAML * *:: *. *:: ::::******************** ENSCPOP00000010958/1-1459 SHCQALSQACNYSEGETVVNVLDFKKDAGLWHGMFSNVMNKMHTISVPYSVMKTCPLSWV ENSP00000301180/1-1576 SHCQALSQACNYSEGETIVNVLDFKKDAGLWHGMFANVMNKMHTISVPYSVMKTCPLSWV XP_004863038.1/1-1503 SHCQALSQACNYSEGETVVNVLDFKKDAGLWHGMFSNVMNKMHTICVPYSVMKTCPLSWV ENSMUSP00000097777/1-1574 SQCQALSQACNYSEGETVVNVLDFKKDAGLWHGMFANVMNKMHTISVPYSVMKTCPLSWV ENSRNOP00000026289/1-1517 SHCQALSQACSYSEGETVVNVLDFKKDAGLWHGMFANVMNKMHTISVPYSVMKTCPLSWV *:********.******:*****************:*********.************** ENSCPOP00000010958/1-1459 QRVHAHKAKVALVKCRDLHWAMMAHRDQRDVSLSSLRMLIVTDGANPWSVSSCDAFLSLF ENSP00000301180/1-1576 QRVHAHKAKVALVKCRDLHWAMMAHRDQRDVSLSSLRMLIVTDGANPWSVSSCDAFLSLF XP_004863038.1/1-1503 QRVHAHKAKVALVKCRDLHWAMMAHRDQRDVSLSSLRMLIVTDGSNPWSVSSCDAFLSLF ENSMUSP00000097777/1-1574 QRVHAHKAKVALVKCRDLHWAMMAHRDQRDVSLSSLRMLIVTDGANPWSVSSCDAFLSLF ENSRNOP00000026289/1-1517 QRVHAHKAKVALVKCRDLHWAMMAHRDQRDVSLSSLRMLIVTDGANPWSVSSCDAFLSLF ********************************************:*************** ENSCPOP00000010958/1-1459 QSHGLKPEAICPCATSAEAMTVAIRRPGVPGAPLPGRAILSMNGLSYGVIRVNTEDKNSA ENSP00000301180/1-1576 QSHGLKPEAICPCATSAEAMTVAIRRPGVPGAPLPGRAILSMNGLSYGVIRVNTEDKNSA XP_004863038.1/1-1503 QSHGLKPEAICPCATSAEAMTVAIRRPGVPGAPLPGRAILSMNGLSYGVIRVNTEDKNSA ENSMUSP00000097777/1-1574 QSHGLKPEAICPCATSAEAMTVAIRRPGVPGAPLPGRAILSMNGLSYGVIRVNTEDKNSA ENSRNOP00000026289/1-1517 QSHGLKPEAICPCATSAEAMTIAIRRPGVPGAPLPGRAILSMNGLSYGVIRVNTEDKNSA *********************:************************************** ENSCPOP00000010958/1-1459 LTVQDVGHVMPGGMMCIVKPDGPPQLCKTDEIGEICVSSRTGGMMYFGLAGVTKNTFEVI ENSP00000301180/1-1576 LTVQDVGHVMPGGMMCIVKPDGPPQLCKTDEIGEICVSSRTGGMMYFGLAGVTKNTFEVI XP_004863038.1/1-1503 LTVQDVGHVMPGGMMCIVKPDGPPQLCKTDEIGEICVSSRTGGMMYFGLAGVTKNTFEVI ENSMUSP00000097777/1-1574 LTVQDVGHVMPGGMMCIVKPDGLPQLCRTDEIGEICVSSRTGGMMYFGLAGVTKNTFEVI ENSRNOP00000026289/1-1517 LTVQDVGHVMPGGMMCIVKPDGLPQLCKTDEIGEICVSSRTGGMMYFGLAGVTKNTFEVI ********************** ****:******************************** ENSCPOP00000010958/1-1459 PMNSAGSPVGDVPFIRSGLLGFVGPGSLVFVVGKMDGLLMVSGRRHNADDIVATGLAVES ENSP00000301180/1-1576 PVNSAGSPVGDVPFIRSGLLGFVGPGSLVFVVGKMDGLLMVSGRRHNADDIVATGLAVES XP_004863038.1/1-1503 PVNSAGSPVGDVPFIRSGLLGFVGPGSLVFVVGKMDGLLMVSGRRHNADDIVATGLAVES ENSMUSP00000097777/1-1574 PVTSSGSPVGDVPFIRSGLLGFVGPGSLVFVVGKMDGLLMVSGRRHNADDIVATGLAVES ENSRNOP00000026289/1-1517 PVTSSGSPVGDVPFIRSGLLGFVGPGSLVFVVGKMDGLLMVSGRRHNADDIVATGLAVES *:.*:******************************************************* ENSCPOP00000010958/1-1459 IKTVYRGRIAVFSVSVFYDERIVVVAEQRPDASEEDSFQWMSRVLQAIDSIHQVGVYCLA ENSP00000301180/1-1576 IKTVYRGRIAVFSVSVFYDERIVVVAEQRPDASEEDSFQWMSRVLQAIDSIHQVGVYCLA XP_004863038.1/1-1503 IKTVYRGRIAVFSVSVFYDERIVVVAEQRPDASEEDSFQWMSRVLQAIDSIHQVGVYCLA ENSMUSP00000097777/1-1574 IKTVYRGRIAVFSVSVFYDERIVVVAEQRPDASEEDSFQWMSRVLQAIDSIHQVGVYCLA ENSRNOP00000026289/1-1517 IKTVYRGRIAVFSVSVFYDERIVVVAEQRPDASEEDSFQWMSRVLQAIDTIHQVGVYCLA *************************************************:********** ENSCPOP00000010958/1-1459 LVPANTLPKTPLGGIHISHTKQLFLEGSLHPCNILMCPHTCVTNLPKPRQKQPGVGPASV ENSP00000301180/1-1576 LVPANTLPKTPLGGIHISQTKQLFLEGSLHPCNILMCPHTCVTNLPKPRQKQPGVGPASV XP_004863038.1/1-1503 LVPANTLPKTPLGGIHISQTKQLFLEGSLHPCNILMCPHTCVTNLPKPRQKQPGVGPASV ENSMUSP00000097777/1-1574 LVPANTLPKTPLGGIHISQTKQLFLEGSLHPCNILMCPHTCVTNLPKPRQKQPGVGPASV ENSRNOP00000026289/1-1517 LVPANTLPKTPLGGIHISQTKQLFLEGSLHPCNILMCPHTCVTNLPKPRQKQPGVGPASV ******************:***************************************** ENSCPOP00000010958/1-1459 MVGNLVAGKRIAQAAGRDLGQIEENDLVRKHQFLAEILQWRAQATPDHVLFMLLNAKGTT ENSP00000301180/1-1576 MVGNLVAGKRIAQAAGRDLGQIEENDLVRKHQFLAEILQWRAQATPDHVLFMLLNAKGTT XP_004863038.1/1-1503 MVGNLVAGKRIAQAAGRDLGQIEENDLVRKHQFLAEILQWRAQATPDHVLFMLLNAKGTT ENSMUSP00000097777/1-1574 MVGNLVAGKRIAQAAGRDLGQIEENDLVRKHQFLAEILQWRAQATPDHVLFMLLNAKGTT ENSRNOP00000026289/1-1517 MVGNLVAGKRIAQAAGRDLGQIEENDLVRKHQFLAEILQWRAQATPDHVLYVLLNAKGTT **************************************************::******** ENSCPOP00000010958/1-1459 VCTASCLQLHKRAERIASVLGDKGHLNAGDNVVLLYPPDILLNCSLHISCCLYAGCIPVT ENSP00000301180/1-1576 VCTASCLQLHKRAERIASVLGDKGHLNAGDNVVLLYPPGIELIAAFYG--CLYAGCIPVT XP_004863038.1/1-1503 VCTASCLQLHKRAERTASVLGDKGHLNAGDNVVLLYPPGIELIAAFYG--CLYAGCIPVT ENSMUSP00000097777/1-1574 VCTASCLQLHKRAERIASVLGDKGHLNAGDNVVLLYPPGIELIAAFYG--CLYAGCIPVT ENSRNOP00000026289/1-1517 VCTASCLQLHKRAERIASVLGDKGHLNAGDNVVLLYPPGIELIAAFYG--CLYAGCIPVT *************** **********************.* * .::: ********** ENSCPOP00000010958/1-1459 VRPPHAQTL-ATLPTVRMIVDVSKAACILTTQTLMRLLRSREAAAAVDVKTWPTIIDTAD ENSP00000301180/1-1576 VRPPHAQNLTATLPTVRMIVDVSKAACILTSQTLMRLLRSREAAAAVDVKTWPTIIDT-D XP_004863038.1/1-1503 VRPPHAQNLTATLPTVRMIVDVSKAACILTTQTLMRLLRSREAAAAVDVKTWPTIIDT-D ENSMUSP00000097777/1-1574 VRPPHAQNLTATLPTVRMVVDVSKAACVLTTQTLMRLLKSREAAAAVDVKTWPAIIDT-D ENSRNOP00000026289/1-1517 VRPPHAQNLTATLPTVRMVVDVSKAACVLTTQTLMRLLKSREAAAAVDVKTWPAIIDT-D *******.* ********:********:**:*******:**************:**** * ENSCPOP00000010958/1-1459 DLPRKRLPQLYKPPTPEMLAYLDFSVSTTGMLTGVKMSHSAVNALCRAIKLQCELYSSRQ ENSP00000301180/1-1576 DLPRKRLPQLYKPPTPEMLAYLDFSVSTTGMLTGVKMSHSAVNALCRAIKLQCELYSSRQ XP_004863038.1/1-1503 DLPRKRLPQLYKPPTPEMLAYLDFSVSTTGMLTGVKMSHSAVNALCRAIKLQCELYSSRQ ENSMUSP00000097777/1-1574 DLPRKRLPQLYKPPTPEMLAYLDFSVSTTGMLTGVKMSHSAVNALCRAIKLQCELYSSRQ ENSRNOP00000026289/1-1517 DLPRKRLPQLYKPPTPEMLAYLDFSVSTTGMLTGVKMSHSAVNALCRAIKLQCELYSSRQ ************************************************************ ENSCPOP00000010958/1-1459 IAICLDPYCGLGFALWCLCSVYSGHQSILIPPMELENNLFLWLATVNQYKIRDTFCSYSV ENSP00000301180/1-1576 IAICLDPYCGLGFALWCLCSVYSGHQSVLIPPMELENNLFLWLSTVNQYKIRDTFCSYSV XP_004863038.1/1-1503 IAICLDPYCGLGFALWCLCSVYSGHQSILIPPMELENNLFLWLATVNQYKIRDTFCSYSV ENSMUSP00000097777/1-1574 IAICLDPYCGLGFALWCLCSVYSGHQSVLIPPMELENNLFLWLATVNQYKIRDTFCSYSV ENSRNOP00000026289/1-1517 IAICLDPYCGLGFALWCLCSVYSGHQSVLIPPMELESNLSLWLATVNQYKIRDTFCSYSV ***************************:********.** ***:**************** ENSCPOP00000010958/1-1459 MELCTKGLGNQVEVLKTRGINLSCIRTCVVVAEERPRITLQQSFSKLFKDIGLSPRAVST ENSP00000301180/1-1576 MELCTKGLGNQVEVLKTRGINLSCVRTCVVVAEERPRVALQQSFSKLFKDIGLSPRAVST XP_004863038.1/1-1503 MELCTKGLGNQVEVLKTRGINLSCIRTCVVVAEERPRITLQQSFSKLFKDIGLSPRAVST ENSMUSP00000097777/1-1574 MELCTKGLGNQVEVLKTRGINLSCIRTCVVVAEERPRVSLQQSFSKLFKDIGLSPRAVST ENSRNOP00000026289/1-1517 MELCTKGLGSQVEALKTRGINLSCIRTCVVVAEERPRVTLQQSFSKLFKDIGLSPRAVST *********.***.**********:************::********************* ENSCPOP00000010958/1-1459 TFGSRVNVAICLQGTSGPDPTTVYVDLKSLRHDRVRLVERGAPQSLLLSESGKILPGVKV ENSP00000301180/1-1576 TFGSRVNVAICLQGTSGPDPTTVYVDLKSLRHDRVRLVERGAPQSLLLSESGKILPGVKV XP_004863038.1/1-1503 TFGSRVNVAICLQGTSGPDPTTVYVDLKSLRHDRVRLVERGAPQSLLLSESGKILPGVKV ENSMUSP00000097777/1-1574 TFGSRVNVAICLQGTSGPDPTTVYVDLKSLRHDRVRLVERGAPQSLLLSESGKILPGVKV ENSRNOP00000026289/1-1517 TFGSRVNVAICLQGTSGPDPTTVYVDLKSLRHDRVRLVERGAPQSLLLSESGKILPGVKV ************************************************************ ENSCPOP00000010958/1-1459 VIVNPETKGPVGDSHLGEIWVNSPHTASGYYTIYDSETLQADHFNTRLSFGDAAQTLWAR ENSP00000301180/1-1576 VIVNPETKGPVGDSHLGEIWVNSPHTASGYYTIYDSETLQADHFNTRLSFGDAAQTLWAR XP_004863038.1/1-1503 VIVNPETKGPVGDSHLGEIWVNSLHTASGYYTIYDSETLQADHFNTRLSFGDAAQTLWAR ENSMUSP00000097777/1-1574 VIVNPETKGPVGDSHLGEIWVNSPHTASGYYTIYDSETLQADHFNTRLSFGDAAQTLWAR ENSRNOP00000026289/1-1517 VIVNPETKGPVGDSHLGEIWVNSPHTASGYYTIYDSETLQADHFNTRLSFGDAAQTLWAR *********************** ************************************ ENSCPOP00000010958/1-1459 TGYLGFVRRTELTAATGERHDALYVVGALDETLELRGLRYHPIDIETSVSRIHRSIAECA ENSP00000301180/1-1576 TGYLGFVRRTELTAATGERHDALYVVGALDETLELRGLRYHPIDIETSVSRIHRSIAECA XP_004863038.1/1-1503 TGYLGFVRRTELTAATGERHDALYVVGALDETLELRGLRYHPIDIETSVSRIHRSIAECA ENSMUSP00000097777/1-1574 TGYLGFVRRTELTAATGERHDALYVVGALDETLELRGLRYHPIDIETSVSRVHRSIAECA ENSRNOP00000026289/1-1517 TGYLGFVRRTELTAATGERHDALYVVGALDETLELRGLRYHPIDIETSVSRVHRSIAECA ***************************************************:******** ENSCPOP00000010958/1-1459 VFTWTNLLVVVVELCGSEQEALDLVPLVTNVVLEEHYLIVGVVVVVDPGVIPINSRGEKQ ENSP00000301180/1-1576 VFTWTNLLVVVVELCGSEQEALDLVPLVTNVVLEEHYLIVGVVVVVDPGVIPINSRGEKQ XP_004863038.1/1-1503 VFTWTNLLVVVVELCGSEQEALDLVPLVTNVVLEEHYLIVGVVVVVDPGVIPINSRGEKQ ENSMUSP00000097777/1-1574 VFTWTNLLVVVVELCGSEQEALDLVPLVTNVVLEEHYLIVGVVVVVDPGVVPINSRGEKQ ENSRNOP00000026289/1-1517 VFTWTNLLVVVVELCGSEQEALDLVPLVTNVVLEEHYLIVGVVVVVDPGVVPINSRGEKQ **************************************************:********* ENSCPOP00000010958/1-1459 RMHLRDSFLADQLDPIYVAYNM ENSP00000301180/1-1576 RMHLRDSFLADQLDPIYVAYNM XP_004863038.1/1-1503 RMHLRDSFLADQLDPIYVAYNM ENSMUSP00000097777/1-1574 RMHLRDSFLADQLDPIYVAYNM ENSRNOP00000026289/1-1517 RMHLRDSFLADQLDPIYVAYNM **********************