CLUSTAL W(1.81) multiple sequence alignment ENSCPOP00000010921/1-1005 MPSTNRAGSLKDPEIAELFFKEDPEKLFTDLREIGHGSFGAVYFARDVRTNEVVAIKKMS ENSRNOP00000021368/1-992 MPSTNRAGSLKDPEIAELFFKEDPEKLFTDLREIGHGSFGAVYFARDVRTNEVVAIKKMS XP_004857618.1/1-945 MPSTNRAGSLKDPEIAELFFKEDPEKLFTDLREIGHGSFGAVYFARDVRTNEVVAIKKMS ENSP00000261716/1-1001 MPSTNRAGSLKDPEIAELFFKEDPEKLFTDLREIGHGSFGAVYFARDVRTNEVVAIKKMS ENSMUSP00000055470/1-1001 MPSTNRAGSLKDPEIAELFFKEDPEKLFTDLREIGHGSFGAVYFARDVRTNEVVAIKKMS ************************************************************ ENSCPOP00000010921/1-1005 YSGKQSTEKWQDIIKEVRFLQRIKHPNSIEYKGCYLREHTAWLVMEYCLGSASDLLEVHK ENSRNOP00000021368/1-992 YSGKQSTEKWQDIIKEVKFLQRIKHPNSIEYKGCYLREHTAWLVMEYCLGSASDLLEGKL XP_004857618.1/1-945 YSGKQSTEKWQDIIKEVRFLQRIKHPNSIEYKGCYLREHTAWLVMEYCLGSASDLLEVHK ENSP00000261716/1-1001 YSGKQSTEKWQDIIKEVKFLQRIKHPNSIEYKGCYLREHTAWLVMEYCLGSASDLLEVHK ENSMUSP00000055470/1-1001 YSGKQSTEKWQDIIKEVKFLQRIKHPNSIEYKGCYLREHTAWLVMEYCLGSASDLLEVHK *****************:*************************************** : ENSCPOP00000010921/1-1005 KPLQEVEIAAITHGALQGLAYLHSHTMIHRPRDIKAGNILLTEPGQVKLADFGSASMASP ENSRNOP00000021368/1-992 VNYKMTKICAISFGSSCS--YLHSHTMIH--RDIKAGNILLTEPGQVKLADFGSASMASP XP_004857618.1/1-945 KPLQEVEIAAITHGALQGLAYLHSHTMIH--RDIKAGNILLTEPGQVKLADFGSASMASP ENSP00000261716/1-1001 KPLQEVEIAAITHGALQGLAYLHSHTMIH--RDIKAGNILLTEPGQVKLADFGSASMASP ENSMUSP00000055470/1-1001 KPLQEVEIAAITHGALQGLAYLHSHTMIH--RDIKAGNILLTEPGQVKLADFGSASMASP : .:*.**:.*: . ********* ***************************** ENSCPOP00000010921/1-1005 ANSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIA ENSRNOP00000021368/1-992 ANSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIA XP_004857618.1/1-945 ANSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIA ENSP00000261716/1-1001 ANSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIA ENSMUSP00000055470/1-1001 ANSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIA ************************************************************ ENSCPOP00000010921/1-1005 QNESPTLQSNEWSDYFRNFVDSCLQKIPQDRPTSEELLKHMFVLRERPETVLIDLIQRTK ENSRNOP00000021368/1-992 QNESPTLQSNEWSDYFRNFVDSCLQKIPQDRPTSEELLKHMFVLRERPETVLIDLIQRTK XP_004857618.1/1-945 QNESPTLQSNEWSDYFRNFVDSCLQKIPQDRPTSEELLK--------------------- ENSP00000261716/1-1001 QNESPTLQSNEWSDYFRNFVDSCLQKIPQDRPTSEELLKHIFVLRERPETVLIDLIQRTK ENSMUSP00000055470/1-1001 QNESPTLQSNEWSDYFRNFVDSCLQKIPQDRPTSEELLKHMFVLRERPETVLIDLIQRTK *************************************** ENSCPOP00000010921/1-1005 DAVRELDNLQYRKMKKLLFQEAHNGPTVEAQEEEEEQDHGVGRTGTVNSVGSNQSIPSMS ENSRNOP00000021368/1-992 DAVRELDN---------LXQEAHNGPAVEAQEEEEEQDHGGGRTGTVNSVGSNQSIPSMS XP_004857618.1/1-945 -----------------------------------EQDHGVGRTGTVNSVGSNQSIPSMS ENSP00000261716/1-1001 DAVRELDNLQYRKMKKLLFQEAHNGPAVEAQEEEEEQDHGVGRTGTVNSVGSNQSIPSMS ENSMUSP00000055470/1-1001 DAVRELDNLQYRKMKKLLFQEAHNGPAVEAQEEEEEQDHGVGRTGTVNSVGSNQSIPSMS ***** ******************* ENSCPOP00000010921/1-1005 ISASSQSSSVNSLPDASDDKSELDMMEGDHTVMSNSSVIHLKPEEENYREEGDSRTRASD ENSRNOP00000021368/1-992 ISASSQSSSVNSLPDASDDKSELDMMEGDHTVMSNSSVIHLKPEEENYQEEGDPRTRASD XP_004857618.1/1-945 ISASSQSSSVNSLPDASDDKSELDMMEGDHTVMSNSSVIHLKPEEENYREEGDCRTRASD ENSP00000261716/1-1001 ISASSQSSSVNSLPDVSDDKSELDMMEGDHTVMSNSSVIHLKPEEENYREEGDPRTRASD ENSMUSP00000055470/1-1001 ISASSQSSSVNSLPDASDDKSELDMMEGDHTVMSNSSVIHLKPEEENYQEEGDPRTRASD ***************.********************************:**** ****** ENSCPOP00000010921/1-1005 PQSPPQVSRHKSHYRNREHFATIRT--ASLVTRQMQEHEQDSELREQMSGYKRMRRQHQK ENSRNOP00000021368/1-992 PQSPPQVSRHKSHYLLQSLCACERKLLCILVTRQMQEHEQDSELREQMSGYKRMRRQHQK XP_004857618.1/1-945 PQSPPQVSRHKSHYRNREHFATIRT--ASLVTRQMQEHEQDSELREQMSGYKRMRRQHQK ENSP00000261716/1-1001 PQSPPQVSRHKSHYRNREHFATIRT--ASLVTRQMQEHEQDSELREQMSGYKRMRRQHQK ENSMUSP00000055470/1-1001 PQSPPQVSRHKSHYRNREHFATIRT--ASLVTRQMQEHEQDSELREQMSGYKRMRRQHQK ************** :. * *. . ******************************* ENSCPOP00000010921/1-1005 QLMSLENKLKSEMDEHRLRLDKDLETQRNNFAAEMEKLIKKHQAAMEKEAKVMANEEKKF ENSRNOP00000021368/1-992 QLMTLENKLKAEMDEHRLRLDKDLETQRNNFAAEMEKLIKKHQASMEKEAKVMANEEKKF XP_004857618.1/1-945 QLMTLENKLKAEMDEHRLRLDKDLETQRNNFAAEMEKLIKKHQAAMEKEAKVMANEEKKF ENSP00000261716/1-1001 QLMTLENKLKAEMDEHRLRLDKDLETQRNNFAAEMEKLIKKHQAAMEKEAKVMSNEEKKF ENSMUSP00000055470/1-1001 QLMTLENKLKAEMDEHRLRLDKDLETQRNNFAAEMEKLIKKHQAAMEKEAKVMANEEKKF ***:******:*********************************:********:****** ENSCPOP00000010921/1-1005 QQHIQAQQKKELNSFLESQKREYKLRKEQLKEKPYLLTSGSTKTEELISFLNNKEDKIQH ENSRNOP00000021368/1-992 QQHIQAQQKKELNSFLESQKREYKLRKEQLKEE--LNENQSTPKKEKQEWLSKQKENIQH XP_004857618.1/1-945 QQHIQAQQKKELNSFLESQKREYKLRKEQLKEE--LNENQSTPKKEKQEWLSKQKENIQH ENSP00000261716/1-1001 QQHIQAQQKKELNSFLESQKREYKLRKEQLKEE--LNENQSTPKKEKQEWLSKQKENIQH ENSMUSP00000055470/1-1001 QQHIQAQQKKELNSFLESQKREYKLRKEQLKEE--LNENQSTPKKEKQEWLSKQKENIQH ********************************: * . ** .:* .:*.:::::*** ENSCPOP00000010921/1-1005 FQAEEEANLLRRQRQYLELECRRFKRRMLLGRHNLEQDLVREELNKRQTQKDLEHAMLLR ENSRNOP00000021368/1-992 FQAEEEANLLRRQRQYLELECRRFKRRMLLGRHNLEQDLVREELNKRQTQKDLEHAMLLR XP_004857618.1/1-945 FQAEEEANLLRRQRQYLELECRRFKRRMLLGRHNLEQDLVREELNKRQTQKDLEHAMLLR ENSP00000261716/1-1001 FQAEEEANLLRRQRQYLELECRRFKRRMLLGRHNLEQDLVREELNKRQTQKDLEHAMLLR ENSMUSP00000055470/1-1001 FQAEEEANLLRRQRQYLELECRRFKRRMLLGRHNLEQDLVREELNKRQTQKDLEHAMLLR ************************************************************ ENSCPOP00000010921/1-1005 QHESMQELEFRHLNIIQKMRCELIRLQHQTELTNQLEYNKRRERELRRKHVMEVRQQPKS ENSRNOP00000021368/1-992 QHESMQELEFRHLNTIQKMRCELIRLQHQTELTNQLEYNKRRERELRRKHVMEVRQQPKS XP_004857618.1/1-945 QHESMQELEFRHLNTIQKMRCELIRLQHQTELTNQLEYNKRRERELRRKHVMEVRQQPKS ENSP00000261716/1-1001 QHESMQELEFRHLNTIQKMRCELIRLQHQTELTNQLEYNKRRERELRRKHVMEVRQQPKS ENSMUSP00000055470/1-1001 QHESMQELEFRHLNTIQKMRCELIRLQHQTELTNQLEYNKRRERELRRKHVMEVRQQPKS ************** ********************************************* ENSCPOP00000010921/1-1005 LKSKELQIKKQFQDTCKIQTRQYKALRNHLLETTPKSEHKAVLKRLKEEQTRKLAILAEQ ENSRNOP00000021368/1-992 LKSKELQIKKQFQDTCKIQTRQYKALRNHLLETTPKSEHKAVLKRLKEEQTRKLAILAEQ XP_004857618.1/1-945 LKSKELQIKKQFQDTCKIQTRQYKALRNHLLETTPKSEHKAVLKRLKEEQTRKLAILAEQ ENSP00000261716/1-1001 LKSKELQIKKQFQDTCKIQTRQYKALRNHLLETTPKSEHKAVLKRLKEEQTRKLAILAEQ ENSMUSP00000055470/1-1001 LKSKELQIKKQFQDTCKIQTRQYKALRNHLLETTPKSEHKAVLKRLKEEQTRKLAILAEQ ************************************************************ ENSCPOP00000010921/1-1005 YDHSINEMLSTQALRLDEAQEAECQVLKMQLQQELELLNAYQSKIKMQAEAQHDRELREL ENSRNOP00000021368/1-992 YDHSINEMLSTQALRLDEAQEAECQVLKMQLQQELELLNAYQSKIKMQAEAQHDRELREL XP_004857618.1/1-945 YDHSINEMLSTQALRLDEAQEAECQVLKMQLQQELELLNAYQSKIKMQAEAQHDRELREL ENSP00000261716/1-1001 YDHSINEMLSTQALRLDEAQEAECQVLKMQLQQELELLNAYQSKIKMQAEAQHDRELREL ENSMUSP00000055470/1-1001 YDHSINEMLSTQALRLDEAQEAECQVLKMQLQQELELLNAYQSKIKMQAEAQHDRELREL ************************************************************ ENSCPOP00000010921/1-1005 GQRVSFRRALLEQKVQRKLFAFQSECMDLVRKILKRKTKILDSLKSQLMTIDFSNMVLSN ENSRNOP00000021368/1-992 EQRVSLRRALLEQKIEEEMLALQNERTERIRSLLERQAREIEAFDSESMRLGFSNMVLSN XP_004857618.1/1-945 EQRVSLRRALLEQKIEEEMLALQNERTERIRSLLERQAREIEAFDSESMRLGFSNMVLSN ENSP00000261716/1-1001 EQRVSLRRALLEQKIEEEMLALQNERTERIRSLLERQAREIEAFDSESMRLGFSNMVLSN ENSMUSP00000055470/1-1001 EQRVSLRRALLEQKIEEEMLALQNERTERIRSLLERQAREIEAFDSESMRLGFSNMVLSN ****:********::.:::*:*.* : :*.:*:*::: ::::.*: * :.******** ENSCPOP00000010921/1-1005 LSHEAFSHSYPGASGWSHNPAGGPGPHWGHPMGGPPQAWGHPMQGGPQPWGHPSGPMQGV ENSRNOP00000021368/1-992 LSPEAFSHSYPGASSWSHNPTGGSGPHWGHPMGGTPQAWGHPMQGGPQPWGHPSGPMQGV XP_004857618.1/1-945 LSPEAFSHSYPGASGWSHNPAGGPGPHWGHPMGGPPQAWGHPMQGGPQPWGHPSGPVQGV ENSP00000261716/1-1001 LSPEAFSHSYPGASGWSHNPTGGPGPHWGHPMGGPPQAWGHPMQGGPQPWGHPSGPMQGV ENSMUSP00000055470/1-1001 LSPEAFSHSYPGASSWSHNPTGGPGPHWGHPMGGTPQAWGHPMQGGPQPWGHPSGPMQGV ** ***********.*****:**.**********.*********************:*** ENSCPOP00000010921/1-1005 PRGSSIGVRNSPQALRRTASGGRTEQGMSRSTSVTSQISNGSHMSYT ENSRNOP00000021368/1-992 PRGSSIGVRNSPQALRRTASGGRTEQGMSRSTSVTSQISNGSHMSYT XP_004857618.1/1-945 PRGSSIGVRNSPQALRRTASGGRTEQGMSRSTSVTSQISNGSHMSYT ENSP00000261716/1-1001 PRGSSMGVRNSPQALRRTASGGRTEQGMSRSTSVTSQISNGSHMSYT ENSMUSP00000055470/1-1001 PRGSSMGVRNSPQALRRTASGGRTEQGMSRSTSVTSQISNGSHMSYT *****:*****************************************