CLUSTAL W(1.81) multiple sequence alignment ENSMUSP00000065949/1-1344 --MFLMPTSSELNSGQNFLTQWMTSPSRAGVILNRGFPILEAD-DKQAATNVSTSFPAKA ENSRNOP00000061061/1-1307 MKMFLMPTSSELNTGQNFLTQWMTSPSRAGVILNREFPILDAD-EKQAATTVSASFPVKA ENSP00000371308/1-1338 --MFLMPTSSELNSGQNFLTQWMTNPSRAGVILNRGFPILEADKEKRAAVDISTSFPIKG ENSCPOP00000010918/1-1333 --MFLMPTSSELNSGQNFLTQWMTNPSRAGVILNRGFPILEADEEKQTATNTST-FLSKT XP_004854954.1/1-1347 --MFLMPASSELNNEQNFLTQWMTSPSRAGVILNRGFPILETDEEKQAATNTSTSFPIKA *****:*****. *********.********** ****::* :*::*. *: * * ENSMUSP00000065949/1-1344 THFSNSFSISSEEDSFHEEQKLEAGGPYKPWSENPEAPPVFPSVRKEP-IASRQDAPGCQ ENSRNOP00000061061/1-1307 AHFSSSFSISSEEDSFHEEQTLEAGRPYKPRSEDPEAHPVSASVRREP-IASCQDAPGCQ ENSP00000371308/1-1338 THFSDSFSFINEEDSLLEEQKLESNNPYKPQSDKSETHTAFPCIKKGPQVAACHSAPGHQ ENSCPOP00000010918/1-1333 TRFSNSFSFSSEEDSLHEELKLESSSPHKLQSQKSEASGILPLIKKKPQIVACQNTPGNQ XP_004854954.1/1-1347 THFSNSFSFISEEDSLHEEQKLESSSPYILQSEKSEAHTVLPLIKKGPQIVACQDVPGDQ ::**.***: .****: ** .**:. *: *:..*: . ::: * :.: :..** * ENSMUSP00000065949/1-1344 EDNNNDLTPHLESEFKEVANKNPLFKKLEQLKEIQQKKQEQLKRQQLEQLQRLMEEQEKL ENSRNOP00000061061/1-1307 EGNRNAATPDLKSEFKEVANKNPLFKKLEQL----------------------------- ENSP00000371308/1-1338 EENKNDFIPDLASEFKEGAYKDPLFKKLEQLKEVQQKKQEQLKRQQLEQLQRLMEEQEKL ENSCPOP00000010918/1-1333 KDNKSDFMPSFDGDFKDVFYKDPLFKKLEQLKEVQQRKQEQLRRQQSEQLQRFLEEQEKL XP_004854954.1/1-1347 KDDKSDFMSNLASEFKEVAYKDPLFKKLEQLKEVQQKKQEQLKRQQLEQLRKLMEEQEKL : :.. . : .:**: *:********* ENSMUSP00000065949/1-1344 LTMVSAQHAFPG-TLLPDDQSQKHRSPGDLT--------LPPHSYSNPTQENSCASNVLP ENSRNOP00000061061/1-1307 --------------------SQKHRSPGDSASGERAT--LSPPSYPNPTQDNSRASSLLP ENSP00000371308/1-1338 LTMVSGQCTLPGLSLLPDDQSQKHRSPGNTTTGERATCCFPSYVYPDPTQEETYPSNILS ENSCPOP00000010918/1-1333 LTVVSGQRVLPGFTLLPDDDSQKYRSPGSTPAREKATPFLPSYVYPNQTQEKLHSSNISF XP_004854954.1/1-1347 LTMVSGQHMLAGFTSLPDDQSQKYRSPGSVPAGEKATPFLPSYVYPSQTQEKLHASNILS ***:****. . :.. *.. **:: .*.: ENSMUSP00000065949/1-1344 DEQSNFCRATQ-DSVLTSKNAS-DLFYESQYQEAHVKRNDLKEESPAHPSGEGALPRWEK ENSRNOP00000061061/1-1307 DEQSNFCRATQQDSVLTSKNAS-DLFHESQYHEAHVRRNDLKEESHNHPSGEGALPCWEK ENSP00000371308/1-1338 HEQSNFCRTAHGDFVLTSKRASPNLFSEAQYQEAPVEKNNLKEENRNHPTGESIL-CWEK ENSCPOP00000010918/1-1333 DEQNNLCKATPHDFVPASKRSSPNLFFESQYQEAIVKKYDLKEDN---PIGESILP-LEK XP_004854954.1/1-1347 DEQ-NFCRVTHHDFVLTSKSAPSNLFYESQYQETIVKKYDSKEENQNHPTGENILPRWEK .** *:*:.: * * :** :. :** *:**:*: *.: : **:. * **. * ** ENSMUSP00000065949/1-1344 KMGRSQEGKDVNLQKCGDSSEVVNIDERPIKAAVREKQQTFEDYLEEQIQLEERELRQKQ ENSRNOP00000061061/1-1307 KMGKSQEGKDVNLQRSRDSSGVVNIEERPIKAAIREKQQTFEDYLEEQIRLEERELRQKQ ENSP00000371308/1-1338 VTEQIQEANDKNLQKHDDSSEVANIEERPIKAAIGERKQTFEDYLEEQIQLEEQELKQKQ ENSCPOP00000010918/1-1333 TTEQIQERNDTN----CDSSEVVNIEVRPIKAVIRERKQTFEDYLEEQIQLDEQALKQKQ XP_004854954.1/1-1347 MTEQIQEGNDISLKKIGDSSEVVNNEERPIKATIRERKQTFEDYLEEQIQLDEQELKQKQ : ** :* . *** *.* : *****.: *::***********:*:*: *:*** ENSMUSP00000065949/1-1344 LQEAEGPLLAKTKPKQPFLKRGEGLARFTNAKSKFQKGKESKLASTQSPSEDQPGSKVDR ENSRNOP00000061061/1-1307 LQEAEGPLLTKMKPKQPFLKRGEGLARFTNAKCKFQKGKESKLASTQSPSEQQSVPKVDR ENSP00000371308/1-1338 LKEAEGPLPIKAKPKQPFLKRGEGLARFTNAKSKFQKGKESKLVTNQSTSEDQPLFKMDR ENSCPOP00000010918/1-1333 LREAEGQL--KAKPKQPFLKRGEGLARFINNKSKLQKGKESKLGTNQNALEDQSLFKVDR XP_004854954.1/1-1347 LREAEGQLIMKAKPKQPFLKRGEGLARFTNAKSKFQKGKESTLGANQNTSEDQSLFKVDS *:**** * * **************** * *.*:******.* :.*.. *:*. *:* ENSMUSP00000065949/1-1344 QHLQRKTALINKDLCAETPTVKKDSKARPKAGFASLRQKPKVTKTNMRESLSPPGLKVQT ENSRNOP00000061061/1-1307 QHLQRKTALINRDLCADTTSVKKDSKARSKAGSASLRQKPKVTKTNRRDSLSPPGRKVQT ENSP00000371308/1-1338 QQLQRKTALKNKELCADNPILKKDSKARTKSGSVTLSQKPKMLKCSNRKSLSPSGLKIQT ENSCPOP00000010918/1-1333 QLFQRKTALINKEPCSENCTVKKENKTRTKFGSVTHNQKPKVPKSNSRKNVSPSGSKIQT XP_004854954.1/1-1347 QQFQRKTAVVNKELCSENLTVKKESKAGSRTGFVTLSQKPKVPKSNNRESVSPSGSKIQT * :*****: *:: *::. :**:.*: .: * .: ****: * . *..:**.* *:** ENSMUSP00000065949/1-1344 GKKRDGQFRHQVKGERNAHASNKENVPACIKPWDAGCKMWSKTQGRERLPLSTGPVGCVV ENSRNOP00000061061/1-1307 GKKCDGQFRPQVKLERNVPTNNKENVPAYIKPWGAGCKVWNKTQGRDRLPLSTGPVGCVV ENSP00000371308/1-1338 GKKCDGQFRDQIKFENKVTSNNKENVTECPKPCDTGCTGWNKTQGKDRLPLSTGPASRLA ENSCPOP00000010918/1-1333 EKKCNGQFREQIKFDS-----NKENVPECTKPCDAGCSVWNKTRGKDRPCLPTGPVGCLA XP_004854954.1/1-1347 GKTCNGQFKEKIKLEKKVDS-NKENEPERTKPCDTGCKGWNKTQGKDRPPLSIRPVSCMA *. :***: ::* : **** . ** .:**. *.**:*::* *. *.. :. ENSMUSP00000065949/1-1344 SRSPIRETDRETESSLDFSLQKKLEIWEREKEKENLELDEFLFLERAADEISFSSNSSFV ENSRNOP00000061061/1-1307 SRSLVPETDRQTESSLDISLQKKLENWEREKEKENLELDEFLFLERAADEISFSSNSSFV ENSP00000371308/1-1338 AKSPIRETMKESESSLDVSLQKKLETWEREKEKENLELDEFLFLEQAADEISFSSNSSFV ENSCPOP00000010918/1-1333 SKSPTSETGKELVSSFDISFQKKLENWEQEKEKENLELDEFLFLEKAAEEISFSSNSSFV XP_004854954.1/1-1347 SKRPISETV-ELGSSLDISLQKKLEYWEQEKEKESLELDEFLFLEKAADEISFSSNSSFV :: ** : **:*.*:***** **:*****.**********:**:*********** ENSMUSP00000065949/1-1344 LRILERDQQICDGHRLSSTPVKAVQQREAQQADPRGQSNCSEIPRYGVAHENESECEAML ENSRNOP00000061061/1-1307 LKILERDQQIYEGHRLSSTPVKAVQPQKAQQADPWGQSNHSEVPRPSVAHEDESEFEAML ENSP00000371308/1-1338 LKILERDQQICKGHRMSSTPVKAV-PQKTNPADPISHCNRSEDLDHT-AREKESECEVAP ENSCPOP00000010918/1-1333 LKILERDQQAHKGHRMSSTPVKAV-QQETHLVDLSAKRDCNEDPDPSPACENKSECEVRA XP_004854954.1/1-1347 LKILEKDQQICKGHRMSSTPVKAV-QQKTHPVDLRTERNSSQGPVPNPALESRSEHEITA *:***:*** .***:******** :::: .* . : .: * *..** * ENSMUSP00000065949/1-1344 LSWGSGS-PDGLRELSCKRSMKAFQTSTSEIQSQWDARDD-GVANSDSSTESEEQHDITI ENSRNOP00000061061/1-1307 LSRGSGS-P-GLRELSCKLSKKAFQNSTSENQGRWDAGDG-DVANSDSSSESEE-HDITI ENSP00000371308/1-1338 KQLHSLSSADELREQPCKI-RKAVQKSTSENQTEWNARDDEGVPNSDSSTDSEEQLDVTI ENSCPOP00000010918/1-1333 GPLASASLPDELKELSCKINGKTFQTGSCEGQMLWNVSDGESVRNSDSSTDSEEQLDVTI XP_004854954.1/1-1347 IPLDSASSTDGLKELSCKISGKAFQMNTSEGRMPWNVSDDEVATGSDSSTASEEQLDITI * * . *:* .** *:.* .:.* : *:. *. . .****: *** *:** ENSMUSP00000065949/1-1344 KPSTEVGDRVFSNREDSPQVCDAKGPIRDTGAQEDKWRDADLDLSDKECSSDESVIVESL ENSRNOP00000061061/1-1307 KPSTEAEDRVFSNREDSPQVCDAKGPSRDTGAQEDQWRDADLDLSDKECSSDESVTVESL ENSP00000371308/1-1338 KPSTEDRERGISSREDSPQVCDDKGPFKDTRTQEDKRRDVDLDLSDKDYSSDESIM-ESI ENSCPOP00000010918/1-1333 KPPMEDREGGFISKEDSPQICHGKGPFRDTRTQDNR-RDVDLDLSDKDYSSDESVVTEGM XP_004854954.1/1-1347 KPPTEDTEGGFSHREDSPQVCDGKGPFRDTRTQENRRRDVDLDLSDKDYSSDESVVTENM **. * : : :*****:*. *** :** :*::: **.*******: *****: *.: ENSMUSP00000065949/1-1344 NNKVLEPLRLPSSQAGSKIDFDDERSWTDLEENPYEHGVIHREEAIYGTPQTQCHSKSEG ENSRNOP00000061061/1-1307 SSQVLEPLRLPSSHDGSKVDFDDERSWADLEENPHEHGVVPREEAMSGTSQTHCHSTSEG ENSP00000371308/1-1338 KHKVSEPSRSSSL-SLSKMDFDDERTWTDLEENLCNHDVVLGNESTYGTPQT-CYPNNEI ENSCPOP00000010918/1-1333 KTKVSEPSRRPLLPSVSQIDFDDERSWTDPEENSCKNDVNLGDEVFYGVPHV-GYSNSGV XP_004854954.1/1-1347 ETKVSEPSRRPLLLSMSKIDFDDERSWTDLEENSCKHDVNLEDEAFYEMPQT-GYPNSDV . :* ** * . *::******:*:* *** ::.* :* .:. :... ENSMUSP00000065949/1-1344 CVLDKTIKRKIAPVKKGEDFKCDRRISPPPP-SDLMVKFFPSLKPKPKLDSHLENESKLN ENSRNOP00000061061/1-1307 CVLDKTIKRKIAPVKKGEDFSKSDRSVSPPP-SDLMVKFFPSLKPKPKLDSHVENEPKLS ENSP00000371308/1-1338 GILDKTIKRKIAPVKRGEDLSKSRRSRSP-PTSELMMKFFPSLKPKPKSDSHLGNELKLN ENSCPOP00000010918/1-1333 CFLDKTIKRKVVPVMKGEVLSQANRSTSPPPTSDLMMQFFPSLKLQSESDSHLGNEPKLN XP_004854954.1/1-1347 YVLDRTVKRKVAPVRKGDDLSKSNRSTSPPPTSDLMMKFFPSLKLKPKSDSHLGNEPKLS .**:*:***:.** :*: :. * .* * *:**::****** :.: ***: ** **. ENSMUSP00000065949/1-1344 LSQDQPPEFMVCFIGDSVRSQVLREKVTELESEIEKFKAENTSLAKLRIERESALEKLRK ENSRNOP00000061061/1-1307 LSQDQPP-------GDSVRSQVLREKVIELESEIEKFKAENTSLAKLRIERESALEKLRK ENSP00000371308/1-1338 ISQDQPP-------GDNARSQVLREKIIELETEIEKFKAENASLAKLRIERESALEKLRK ENSCPOP00000010918/1-1333 MSQDQPS-------GDNARSQALREKVVELDTEIEKFKAENASLAKLRMEQESAMEKLRK XP_004854954.1/1-1347 LSQDQPS-------GDSARSQALREKVVELETEIEKFKAENASLAKLRMERESAMEKLRR :*****. **..***.****: **::*********:******:*:***:****: ENSMUSP00000065949/1-1344 EIADFEQQKARELARIEEYRKEETRKLQKERKVFEKYTAAARTFPDKKEREEIQALKQQI ENSRNOP00000061061/1-1307 EIADFEQQKARELARIEEYKKEETRKLQKERKVFEKYTAAARTFPDKKEREEIQACRHSI ENSP00000371308/1-1338 EIADFEQQKAKELARIEEFKKEEMRKLQKERKVFEKYTTAARTFPDKKEREEIQTLKQQI ENSCPOP00000010918/1-1333 ETADFEQQKVKELARIEDLKKEEMRKLQKERKVFEKYATAARTFPDKKEREEIQALKQQI XP_004854954.1/1-1347 ETADFEQQKAKELARIEEFKKEEMRKLQKERKVFEKYTTAARTFPDKKEREEIQALKHQI * *******.:******: :*** *************::***************: ::.* ENSMUSP00000065949/1-1344 ADLQEDLKRKETKWSSTQSRLRSQIEMLVKENTDLREEIKVMERFRLDAWKRAEAMENSP ENSRNOP00000061061/1-1307 QELQEDLKRKETKWSSTHGRLRSQIEMLVKENTDLREEIKVMERFRLEAWKRAEAIENSP ENSP00000371308/1-1338 ADLREDLKRKETKWSSTHSRLRSQIQMLVRENTDLREEIKVMERFRLDAWKRAEAIESS- ENSCPOP00000010918/1-1333 EDLQEDLKKKETKWSSTYGRLRSQIEMLVRENTDLREEIKVMERFRLDAWKKAEAIESSP XP_004854954.1/1-1347 EDLQEDLKRKEAKWTSSYGRLRSQIEMLVRENTDLREEIKVMERFRLDAWKKAEAIESSP :*:****:**:**:*: .******:***:*****************:***:***:*.* ENSMUSP00000065949/1-1344 KACQYMMATKKDESMNSSFQFQKSHVSSGVQVEKYKKKYLPAQGNLSRRIKSAPPRDLGS ENSRNOP00000061061/1-1307 KACQYIMATKKDESMNSSIQFQKSHASLGVQGEKYKKKYLPAQGNSSRRSKSVPPRDLGS ENSP00000371308/1-1338 -----LEVEKKDKLANTSVRFQNSQISSGTQVEKYKKNYLPMQGNPPRRSKSAPPRDLGN ENSCPOP00000010918/1-1333 KAYQCVTARKRDESLNTSVRYQKSHISSGTQGEKYKKNCLPKHGNPSRRSKSVPPQELGS XP_004854954.1/1-1347 KAYQCVTAGKKDESMSTSVRYHKSHISSGAQGEKYKKNYLPKHGNPSQRSKSVPPRDLGS : . *:*: .:*.::::*: * *.* *****: ** :** .:* **.**::**. ENSMUSP00000065949/1-1344 SDKGQAALPREPLQQVNFPDLEYKNKEEKEEEIQGEISHPDGK-VEKIYKNGRRVVLFPN ENSRNOP00000061061/1-1307 LDKGQAALPREPLQPVNFPDLEYKNKEEKEEEIQGEINHPDGK-VEKVYKNGCRVVLFPN ENSP00000371308/1-1338 LDKGQAASPREPLEPLNFPDPEYK-EEEEDQDIQGEISHPDGK-VEKVYKNGCRVILFPN ENSCPOP00000010918/1-1333 SDKEQAALPREPFKPISLLDPEYR--KEKNQEIQEEISHPDGKVVEKIYKNGYQIILFPN XP_004854954.1/1-1347 SDKGQAALPREPLEPLTFLDPEYK-KEEKEEEIQEEISHSDGK-VEKVYKNGYQVTLFPN ** *** ****:: :.: * **: :*::::** **.*.*** ***:**** :: **** ENSMUSP00000065949/1-1344 GTRKEVSADGKSVTVTFFNGDVKQVMPDERVVYYYAAAQTTHTTYPEGLEVLHFSSGQI- ENSRNOP00000061061/1-1307 GTRKEVSADGKSITVTFFNGDVKQVMPDERVVYYYAAAQTTHTTYPEGLEVLHFSSGQIE ENSP00000371308/1-1338 GTRKEVSADGKTITVTFFNGDVKQVMPDQRVIYYYAAAQTTHTTYPEGLEVLHFSSGQI- ENSCPOP00000010918/1-1333 GTQKEVSADGKSITVTFFNGDVKQVMPDGRVIYYYAAAQTTHTTHPEGLEVLHFSSGQI- XP_004854954.1/1-1347 GTRKEVSADGKTVTVTFFNGDLKQVTPDGRVIYYYAAAQTTHTTYPEGLEVLHFSSGQI- **:********::********:*** ** **:************:************** ENSMUSP00000065949/1-1344 ----------EKHFPDGRKEITFPDQTIKTLFADGQEESIFPDGTIVRVQRDGNKIIEFN ENSRNOP00000061061/1-1307 NILITIIFKTEKHFPDGRKEITFPDQTIKTLFADGQEESIFPDGTIVRVQRDGNKIIEFN ENSP00000371308/1-1338 ----------EKHYPDGRKEITFPDQTVKNLFPDGQEESIFPDGTIVRVQRDGNKLIEFN ENSCPOP00000010918/1-1333 ----------EKHFPDGRKEITFPDQTIKNLFADGQEESIFPDGTVVRVQRDGEKIIEFN XP_004854954.1/1-1347 ----------EKHFPDGRKEITFPDQIIKNLFADGQEESIFPDGTVVRVQRDGNKIIEFN ***:************ :*.**.************:*******:*:**** ENSMUSP00000065949/1-1344 NGQRELHTAQFKRREYPDGTVKTVYANGHQETKYTSGRVRVKDKDGNVLMDTEM ENSRNOP00000061061/1-1307 NGQRELHTAQFKRREYPDGTVKTVYANGHQETKYTSGRVRVKDKDGNVLMDTEM ENSP00000371308/1-1338 NGQRELHTAQFKRREYPDGTVKTVYANGHQETKYRSGRIRVKDKEGNVLMDTEL ENSCPOP00000010918/1-1333 NGQRELHTAQFKRREYPDGTVKTVYANGHQETKYTSGRVRVKDKDGNVLMDTEL XP_004854954.1/1-1347 NGQRELHTAQFKRREYPDGTVKTVYTNGHQETKYASGRVRVKDKDGNVLMDSEL *************************:******** ***:*****:******:*: