CLUSTAL W(1.81) multiple sequence alignment ENSMUSP00000063609/1-862 MACGAAERGPEPPAFQRHLEASTQRLAHGYGLRSMSELRDQEFGRLAGTVYLDHAGATLF ENSRNOP00000061024/1-698 ------------------------------------------------------------ ENSP00000261326/1-888 MAGAAAESGRELWTFAGSRDPSAPRLAYGYGPGSLRELRAREFSRLAGTVYLDHAGATLF ENSCPOP00000010886/1-874 LAGLTARWADEPLAFPQCWDPSAPRLARGYGQRSLRELRESEFGRLAETIYLDHAGATLF XP_004855288.1/1-886 MAGGVAGPGAERPTFTRCWDPSTLRLAHGYGPRSVRELRESEFGRLAETVYLDHAGATLF ENSMUSP00000063609/1-862 PQSQLTNFTKDLMENVYG-NPHSQNITSKLTHDTVEQVRYRILTHFHTTPEDYIVIFTAG ENSRNOP00000061024/1-698 ------------------------------------------------------------ ENSP00000261326/1-888 SQSQLESFTSDLMENTYG-NPHSQNISSKLTHDTVEQVRYRILAHFHTTAEDYTVIFTAG ENSCPOP00000010886/1-874 PQSQLTNFTKDLMENVYGSNPHSQSISSKLTHDTVEQVRYRVLAHFHTTPEDYSMVFTSG XP_004855288.1/1-886 PQSQLTNFTKDLLENVYG-NPHSQNITSKLTHDTVEQVRYRVLAHFHTTPEDYSMVFTSG ENSMUSP00000063609/1-862 STAALRLVAEAFPWVSRSPENSGSHFCYLTDNHTSVVGMRKVAAAMSVTSIPVKPEDMWS ENSRNOP00000061024/1-698 ---------------------------------------------MNVTSTPVKPEDMWS ENSP00000261326/1-888 STAALKLVAEAFPWVSQGPESSGSRFCYLTDSHTSVVGMRNVTMAINVISTPVRPEDLWS ENSCPOP00000010886/1-874 STAALKLVAEAFPWVSRGPENSKSQFCYLTDNHTSVVGMRKVAEAMDITSTAVSPEDMRA XP_004855288.1/1-886 STAALKLVAEAFPWVSRGPENGGSQFCYLTDNHTSVVGMRKVAEARNVTSTPVSPEDMWS .: * .* ***: : ENSMUSP00000063609/1-862 AEGKDAGACDPDCQLPHLFCYPAQSNFSGTRYPLSWVEEVKSGRRSPVNAPGKWFVLLDA ENSRNOP00000061024/1-698 AEGKGAGACDPDCQLPHLFCYPAQSNFSGTRYPLSWIDEVKSGQRSPVRAPGKWFVLLDA ENSP00000261326/1-888 AEERSASASNPDCQLPHLFCYPAQSNFSGVRYPLSWIEEVKSGRLHPVSTPGKWFVLLDA ENSCPOP00000010886/1-874 AEERGAVACDPDCQLPHLFCYPAQSNFSGTRYPLSWIEQVKSGRLGPVDVPGKWFVLLDA XP_004855288.1/1-886 AEERGALACEPDCQLPHLFCYPAQSNFSGTRYPLSWIEEVRSGRLSPANVPGKWFVLLDA ** :.* *.:*******************.******:::*:**: *. .********** ENSMUSP00000063609/1-862 ASYVSTSPLDLSAHQADFIPISFYKIFGLPTGLGALLVNKHVAPLLRKGYFGGGTAAAYL ENSRNOP00000061024/1-698 ASYVSTSPLDLSAHQADFIPISFYKIFGLPTGLGALLVNKRVAPLLRKGYFGGGTAAVYL ENSP00000261326/1-888 ASYVSTSPLDLSAHQADFVPISFYKIFGFPTGLGALLVHNRAAPLLRKTYFGGGTASAYL ENSCPOP00000010886/1-874 ASYVSTSPLDLSAHQADFVPISFYKIFGFPTGLGALLINNRVAPLLRKSYFGGGTAAAYL XP_004855288.1/1-886 ASYVSTSPLDLSAHQADFVPISFYKIFGFPTGLGALLINNRVAPLLRKSYFGGGTAAAYL ******************:*********:********::::.****** *******:.** ENSMUSP00000063609/1-862 AGEDFYVPRSSVAERFEDGTISFLDVIALKHGFDALEHLTGGMVNIQQHTFALVQYTHSA ENSRNOP00000061024/1-698 AGEDFYIPRSSVAERFEDGTISFLDVIALKHGFDVLERLTGGMVNIQQHTFALLHFTHSA ENSP00000261326/1-888 AGEDFYIPRQSVAQRFEDGTISFLDVIALKHGFDTLERLTGGMENIKQHTFTLAQYTYVA ENSCPOP00000010886/1-874 AGEDFYVSRPSVAERFEDGTISYLDVIALKHGFDALERLTGGMENIAQHTFTLARYTYAT XP_004855288.1/1-886 AGEDFYIPRPSVAERFEDGTISYLDVIALKHGFDALERLTGGMENIMQYTFMLAQYTHTA ******:.* ***:********:***********.**:***** ** *:** * ::*: : ENSMUSP00000063609/1-862 LSSLRYLNGAPVVRIYSDSEFSSPDVQGPIINFNVLDDGGKIIGYSQVDKMASLYNIHLR ENSRNOP00000061024/1-698 LSSLRYPNGAPVVRIYGDSGFSSPDVQGPIINFNVLDDAGKIIGYSQVDKMASLYNIHLR ENSP00000261326/1-888 LSSLQYPNGAPVVRIYSDSEFSSPEVQGPIINFNVLDDKGNIIGYSQVDKMASLYNIHLR ENSCPOP00000010886/1-874 LSSLRYSNGAPVVQIYSDSEFSSPEVQGPIINFNVLDDSGNIIGYSEVDKMASLYNIHLR XP_004855288.1/1-886 LSSLRYPNGAPVVQIYSDSEFSSPDVQGPIINFNVLDNGGNIIGYSEVDKMASLYNIHLR ****:* ******:**.** ****:************: *:*****:************* ENSMUSP00000063609/1-862 TGCFCNLGACQRHLGLSDEMVKKHFQAGHVCGDDVDIIDGRPTGSVRISFGYMSTLEDAQ ENSRNOP00000061024/1-698 TGCFCNLGACQRHLGLSEEMVKKHFQAGHVCGDDVDIIDGRPTGSVRISFGYMSTLEDAQ ENSP00000261326/1-888 TGCFCNTGACQRHLGISNEMVRKHFQAGHVCGDNMDLIDGQPTGSVRISFGYMSTLDDVQ ENSCPOP00000010886/1-874 TGCFCNTGACQRHLGISNEMVKKYFEAGHVCGDNIDLVDGQPTGSVRISFGYMSTFEDAQ XP_004855288.1/1-886 TGCFCNTGACQRHLGISNEMVKKHLEAGHVCGDSLDLIDGQPTGSVRISFGYMSSVEDAQ ****** ********:*:***:*:::*******.:*::**:*************:.:*.* ENSMUSP00000063609/1-862 AFLRFISTIYLRSPSDQPVPQ--ASISDAGALTSKS-----------DCHSPQEGSCTDP ENSRNOP00000061024/1-698 AFLRFISTIYLRSPGGQPVPQ--ASTSDTGVLSSKS-----------DCQSPQEGPCADP ENSP00000261326/1-888 AFLRFIIDTRLHSSGDWPVPQAHADTGETGAPSADSQADVIPAVMGRRSLSPQEDALTGS ENSCPOP00000010886/1-874 AFLRFIIATRLGSPGDQHVPQ--ASTEEARTPSAEGKVQDMLTAAGRDCISLQKG--MDS XP_004855288.1/1-886 AFLRFIIATRLCLPGGQPVPQ--GSTGKAGAPSAEGKAQDTPAVTGRHCVSPQEGARMDS ****** * ... *** .. .: . ::.. . * *:. .. ENSMUSP00000063609/1-862 SVCNGSYPDTNIMDLHPSLSKASSAQQTPQDKAAGILNGDPGSHIVTNIYLYPIKSCAAF ENSRNOP00000061024/1-698 AVSSGSYPDINTVDLDLSQSKASSIQPIPQEKVAGILNGDLGSHIVTNIYLYPIKSCAAF ENSP00000261326/1-888 RVWNNS-STVNAVPVAPPVCDVARTQPTPSEKAAGVLEGALGPHVVTNLYLYPIKSCAAF ENSCPOP00000010886/1-874 GVWNNSSSTMNTMSLCPTLSKTTNTQQTPTEEAAGILPGDLGPHSVTNLYLYPIKSCAAF XP_004855288.1/1-886 GVWNDSSSTVNSVDLCPAMGKATRTQPTPSEKAAGILPGDLGPHIVTNLYLYPIKSCAAF * ..* . * : : . ..: * * ::.**:* * *.* ***:*********** ENSMUSP00000063609/1-862 EVTKWPVGSQGLLYDRSWMVVNHNGICMSQKQEPRLCLIQPFIDLQQRIMVIKAEGMEPI ENSRNOP00000061024/1-698 EVTKWPVGSQGLLYDRSWMVVNHNGVCLSQKQEPRLCLIQPCIDLQQKVMVIKAEGMEPI ENSP00000261326/1-888 EVTRWPVGNQGLLYDRSWMVVNHNGVCLSQKQEPRLCLIQPFIDLRQRIMVIKAKGMEPI ENSCPOP00000010886/1-874 EVTRWPVGNQGLLYDRSWMVVNHNGICLSQKQEPRLCLIQPFINLQQRIMVIKAKGMEPI XP_004855288.1/1-886 EVTRWPIGKHGLLYDRSWMIVNHNGICLSQKQEPRLCLIQPFIDLQQRIMVIKAKGMEPI ***:**:*.:*********:*****:*:************* *:*:*::*****:***** ENSMUSP00000063609/1-862 QVPLEEDGEQTQICQSRVCADRVNTYDCGENVSRWLSKFLGRLCHLIKQSPHFQRNARKT ENSRNOP00000061024/1-698 QVPLEEDGERTQICQSRVCADRVNTYDCGENVSRWLSKFCGRPCHLIKQSPHFQRNAKKT ENSP00000261326/1-888 EVPLEENSERTQIRQSRVCADRVSTYDCGEKISSWLSTFFGRPCHLIKQSSNSQRNAKKK ENSCPOP00000010886/1-874 EVPLEEDNERIQICQSRVCTDRVNTYDCGEKISSWLSKFLGRPCHLIKQSSNLQRNAKKK XP_004855288.1/1-886 EMPLEEDSGRVQICQSIVCTDRINTYDCGEKISSWLSEFLGRPCHLIKQSSNFQRNAKK- ::****:. : ** ** **:**:.******::* *** * ** *******.: ****:* ENSMUSP00000063609/1-862 PKKGQPPGTTVALSLVNEAQYLLVNTSSILELQRQLNASDEHGKEESFSMKDLISRFRAN ENSRNOP00000061024/1-698 PKQGHPPGTAVALSLVNEAQYLLVNTSSVLELQQQLNASDERGKEESFSVKDLISRFRAN ENSP00000261326/1-888 HGKDQLPGTMATLSLVNEAQYLLINTSSILELHRQLNTSDENGKEELFSLKDLSLRFRAN ENSCPOP00000010886/1-874 QGKDQPVGITATLSLVNEAQYLLINTSSILELHQHLNTSDENGKEELFPMKDLISRFRAN XP_004855288.1/1-886 HGKDQSTGITATLSLVNEAQYLLVNTSSILELHQQLNTSDENGKEKLFPMKDLISRFRAN :.: * .:***********:****:***:::**:***.***: *.:*** ***** ENSMUSP00000063609/1-862 IITKGARAFEEEKWDEISIGSLHFQVLGPCHRCQMICINQQTGQRNQDVFQTLSESRGRK ENSRNOP00000061024/1-698 IITKGARAFEEEQWDEISIGSLHFQVLGPCHRCQMICIDQKTGQRNQDVFQKLSESRGRK ENSP00000261326/1-888 IIINGKRAFEEEKWDEISIGSLRFQVLGPCHRCQMICIDQQTGQRNQHVFQKLSESRETK ENSCPOP00000010886/1-874 IIMSGTKAFEEEKWDEVSIGPLHFQVMGPCHRCQMICINQQTGQLNQDVFQKLSESRTRK XP_004855288.1/1-886 IIMNGTRAFEEEKWDEVSIGSLHFQVQGPCHRCQMICINQQTGQRNQDVFQKLSESRKRK ** .* :*****:***:***.*:*** ***********:*:*** **.***.***** * ENSMUSP00000063609/1-862 VNFGVYLMHSYLDLSSPCFLSVGSEVLPVLKDCGVS-------------- ENSRNOP00000061024/1-698 VNFGVYLMHSSLDLSSPCFLSVGSEVLPVLKDCGVS-------------- ENSP00000261326/1-888 VNFGMYLMHASLDLSSPCFLSVGSQVLPVLKENVEGHDLPASEKHQDVTS ENSCPOP00000010886/1-874 VKFGVYLMHTSLDSSSPCFLSVGSQVVPVLKENAGHHD------------ XP_004855288.1/1-886 VNFGVYLIHRSLDSSSPCFLSVGSQVFSVLKENVEHHDLPASEKCQDLVS *:**:**:* ** **********:*..***: