CLUSTAL W(1.81) multiple sequence alignment ENSCPOP00000010857/1-1003 -------------LSMFLLQLQSYFAACEDETPAIRNHDKVLQRLCEHLDHALLYGLQDL XP_004850396.1/1-1006 MEPREVKDRILENISLSVKKLQSYFAACEDETPAIRNHDKVLQRLCEHLDHALLYGLQDL ENSP00000364956/1-1019 MEPGEVKDRILENISLSVKKLQSYFAACEDEIPAIRNHDKVLQRLCEHLDHALLYGLQDL ENSMUSP00000081221/1-1033 MEPREVKDRILENISLSVKKLQSYFAACEDETPAIRNHDKVLQRLCEHLDHALLYGLQDL ENSRNOP00000016333/1-1031 MEPREVKDRILENISLSVKKLQSYFAACEDETPAIRNHDKVLQRLCEHLDHALLYGLQDL :*: : :*********** **************************** ENSCPOP00000010857/1-1003 SSGYWVLVVHFTRKEAIKQIEVLQHVATNLGRSRAWLYLALNENSLESYLRLFQENLGLL XP_004850396.1/1-1006 SSGYWVLVVHFTRREAIKQIEVLQHVATNLGRSRAWLYLALNENSLESYLRLFQENLGLL ENSP00000364956/1-1019 SSGYWVLVVHFTRREAIKQIEVLQHVATNLGRSRAWLYLALNENSLESYLRLFQENLGLL ENSMUSP00000081221/1-1033 SSGYWVLVVHFTRREAIRQIEVLQHVATNLGRSRAWLYLALNENSLESYLRLFQENLGLL ENSRNOP00000016333/1-1031 SSGYWVVVVHFTRREAIRQIEVLQHVATNLGRSRAWLYLALNENSLESYLRLFQENLGLL ******:******:***:****************************************** ENSCPOP00000010857/1-1003 QKYYVRNALVCSHDHLTLFLTLVSGLEFIRFDLELDAPYLDLAPYMPDYYKPQNLLDFED XP_004850396.1/1-1006 QKYYVRNALVCSHDHLTLFLTLVSGLEFIRFDLELDAPYLDLAPYMPDYYKPQNLLDFED ENSP00000364956/1-1019 HKYYVKNALVCSHDHLTLFLTLVSGLEFIRFELDLDAPYLDLAPYMPDYYKPQYLLDFED ENSMUSP00000081221/1-1033 QKYYVRNALVCSHDHLTLFLTLVSGLEFIRFDLDLDAPYLDLAPYMPDYYKPQYLLDFED ENSRNOP00000016333/1-1031 QKYYVRNALVCSHDHLTLFLTLVSGLEFIRFDLDLDAPYLDLAPYMPDYYKPQYLLDFED :****:*************************:*:******************* ****** ENSCPOP00000010857/1-1003 RLPSSVHGSDSLSLNSFNSVTSTNLEWDDSAIAPSSEDYDFGDVFPAVPSVPSTDWEADG XP_004850396.1/1-1006 RLPSSVHGSDSLSLNSFNSVTSTNLEWDDSAIAPSSE---------------------DG ENSP00000364956/1-1019 RLPSSVHGSDSLSLNSFNSVTSTNLEWDDSAIAPSSEDYDFGDVFPAVPSVPSTDWE-DG ENSMUSP00000081221/1-1033 RLPSSVHGSDSLSLNSFNSVTSTNLEWDDSAIAPSSEDYDFGDVFPAVPSVPSTDWE-DG ENSRNOP00000016333/1-1031 RLPSSVHGSDSLSLNSFNSVTSTNLEWDDSAIAPSSEDYDFGDVFPAVPSVPSTDWE-DG ************************************* ** ENSCPOP00000010857/1-1003 DLTDTISGPRSTASDLTSSKASTRSPTQRHNPFNEEQAETVSSSETTPVHATSQDKGDSQ XP_004850396.1/1-1006 DLTDTVSGPRSTASDLTSSKASTKSPTQRHNPFNEEQTEMVSSSDTTPVHTTSQN-GESQ ENSP00000364956/1-1019 DLTDTVSGPRSTASDLTSSKASTRSPTQRQNPFNEEPAETVSSSDTTPVHTTSQEKEEAQ ENSMUSP00000081221/1-1033 DLTDTISGPRSTASDLTSSKTSTKSPTQRHNPFNEEQAET-ASSDTTPVHTTSQEKEEAQ ENSRNOP00000016333/1-1031 DLTDTISGPRSTASDLTSSKASTKSPTQRHNPFNEEQAES-ASSETTPVHTTSQEKEEAQ *****:**************:**:*****:****** :* :**:*****:***: ::* ENSCPOP00000010857/1-1003 VLEPPDACTELEVIRVTKKKKTGKRKKIRPDEEASPLHPASSQHTGARQGDGDSLVSSPG XP_004850396.1/1-1006 VLEPPDACTELEVIRVTKKKKTGKRKKIRPDEEASPLHPISSQQASVRQGDGDSLVSSLG ENSP00000364956/1-1019 ALDPPDACTELEVIRVTKKKKIGKKKKSRSDEEASPLHPACSQKKCAKQGDGDSRNGSPS ENSMUSP00000081221/1-1033 APDQPDACTELEVIRVTKKKKIGKKKKTKLDEDASPLHPTSSQQKCGQQGEGDGLVGTPG ENSRNOP00000016333/1-1031 APDQPDACTELEVIRVTKKKKIGKKKKTKLDEEASPLHPNCSQQKCGRQGDGDGLVGTPG . : ***************** **:** : **:****** .**: :**:**. .: . ENSCPOP00000010857/1-1003 LGQDSPDTTLASPPEEGEGPSSTAESSEHSELGQVGLLIPEMKDTSMEYLGQPLSKVIDQ XP_004850396.1/1-1006 LGQDSLDTTSASLPEEFEGPTSAPETSEQSELGQVGLLIPEMKDTSMERLGQPLRKVIDQ ENSP00000364956/1-1019 LGRDSPDTMLASPQEEGEGPSSTTESSERSEP---GLLIPEMKDTSMERLGQPLSKVIDQ ENSMUSP00000081221/1-1033 LARDPSDTVLASPQEQGEGLSSTAGSSELSELSQMGLLIPEMKDTSMECLGQPLSKVIDK ENSRNOP00000016333/1-1031 LARNCSDTILASPQEQGEGPGSTAGSCEHSELSQMGLLIPEMKDTSMECLGQPLSKVIDQ *.:: ** ** *: ** *:. :.* ** ************* ***** ****: ENSCPOP00000010857/1-1003 LHGQLDPSTWGSHMETPNQSFRTSAPGEAPEKPPFCDFSEGLPAPMDFYRFTIESPSAVT XP_004850396.1/1-1006 LHGQLDPSTWSSHVEPPDQSFRTSSPGEAPEKPPFCDFSEGLPAPMDFYRFTVESPSTVT ENSP00000364956/1-1019 LNGQLDPSTWCSRAEPPDQSFRTGSPGDAPERPPLCDFSEGLSAPMDFYRFTVESPSTVT ENSMUSP00000081221/1-1033 LHGQLDPSTWCSHADPPEQSFRAGSPGEAPEKPPFCDFSEGLPAPMDFYRFTVESPSTVA ENSRNOP00000016333/1-1031 LHGQLDPSTWCSRVEPPDQSFRTGSPGEAPEKPPFCDFSEGLPAPMDFYRFTVESPSTVA *:******** *: :.*:****:.:**:***:**:*******.*********:****:*: ENSCPOP00000010857/1-1003 SGGGNHDPTGAGQPLHVSGGPTAASQEEE--GGGGEGQTPGLLDDAPG-AAQEL---EED XP_004850396.1/1-1006 SGGSNHDLAGFGQPLHVPGGPAAASQEEE--GGGGEGQTSGLLEDVPG-VAQELETQEED ENSP00000364956/1-1019 SGGGHHDPAGLGQPLHVPSSPEAAGQEEE--GGGGEGQTPRPLEDTTR-EAQEL-----E ENSMUSP00000081221/1-1033 PGGGHHDPPGPSQPLHVPGSPAAALQEEEEGGGRGEGQTSQPLEDRQGEEIQEPEPQEPD ENSRNOP00000016333/1-1031 PGGGHHDPPGSSQPLHVPGSPAPALQEEE--GGRGEGQTSQPLEDQQGKEIQEPEPQEPD .**.:** .* .*****...* .* **** ** *****. *:* ** : ENSCPOP00000010857/1-1003 SQPALVPEGPG----SQPELQIQEAPCPLKGDQPSPCLSSAEDSGVDEGQGSPSDMTHSS XP_004850396.1/1-1006 SQPPLVLEGPG----SKPELQTQETSCPLKQDQPSPCLSSAEDSGVDEGQGSPSEMTHSS ENSP00000364956/1-1019 AQLSLVREGPV----SEPEPGTQEVLCQLKRDQPSPCLSSAEDSGVDEGQGSPSEMVHSS ENSMUSP00000081221/1-1033 SQLPLVSQEPVPEPVSQPEPGTHEALCKLKRDQPSPCLSSAEDSGVEEGQGSPSEMTHPS ENSRNOP00000016333/1-1031 SQLPLVSQEPGPEPVSQPEPGTQETLCKLKGDQPSPCLSSAEDSGVDEGQGSPSEMTHPS :* .** : * *:** :*. * ** ***************:*******:*.*.* ENSCPOP00000010857/1-1003 EFRVDNNHLLLLMIHVFRENEEQLFKMIQMSTGHMEGNLQLLYVLLTDCYVYLLRKGATE XP_004850396.1/1-1006 EFRVDNNHLLLLMIHVFRENEEQLFKMIRMSTGHMEGNLQLLYVLLTDCYVYLLRKGATE ENSP00000364956/1-1019 EFRVDNNHLLLLMIHVFRENEEQLFKMIRMSTGHMEGNLQLLYVLLTDCYVYLLRKGATE ENSMUSP00000081221/1-1033 EFRVDNNHLLLLMIHVFRENEEQLFKMIRMSTGHMEGNLQLLYVLLTDCYVYLLRKGATE ENSRNOP00000016333/1-1031 EFRVDNNHLLLLMIHVFRENEEQLFKMIRMSTGHMEGNLQLLYVLLTDCYVYLLRKGATE ****************************:******************************* ENSCPOP00000010857/1-1003 KPYLVEEAVSYNELDYVSVGLDQQTVKLVCTNRRKQFLLDTADVALAEFFLASLKSAMIK XP_004850396.1/1-1006 KPYLVEEAVSYNELDYVSVGLDQQTVKLVCTNRRKQFLLDTADVALAEFFLASLKSAMIK ENSP00000364956/1-1019 KPYLVEEAVSYNELDYVSVGLDQQTVKLVCTNRRKQFLLDTADVALAEFFLASLKSAMIK ENSMUSP00000081221/1-1033 KPYLVEEAVSYNELDYVSVGLDQQTVKLVCTNRRKQFLLDTADVALAELFLASLKSAMIK ENSRNOP00000016333/1-1031 KPYLVEEAVSYNELDYVSVGLDQQTVKLVCTNRRKQFLLDTADVALAELFLASLKSAMIK ************************************************:*********** ENSCPOP00000010857/1-1003 GCREPPYPSVLTDATMEKLALAKFVAQESKCEASTVTVHFYGLVHWEDPMD--------- XP_004850396.1/1-1006 GCREPPYPSILTDATMEKLALAKFVAQESKCEASTVTVHFYGLVHWEDPMDEVLDPVPCH ENSP00000364956/1-1019 GCREPPYPSILTDATMEKLALAKFVAQESKCEASAVTVRFYGLVHWEDPTDESLGPTPCH ENSMUSP00000081221/1-1033 GCREPPYPSILTDATMEKLALAKFVAQESKCEASAVTVHFYGLVHWEDPMEEALGPVPCQ ENSRNOP00000016333/1-1031 GCREPPYPSVLTDATMERLALAKFVAQESKCEASTVTVHFYGLVHWEDPMEEALGPVPCQ *********:*******:****************:***:********** : ENSCPOP00000010857/1-1003 CSPPEGAITKEGVLHYKAGTSYLGKEHWKTCFVVLSNGILYQYPDRTDVIPLLSVNMGGE XP_004850396.1/1-1006 CSPLEGAITKEGVLHYKAGTSYLGKEHWKTCFVVLSNGILYQYPDRTDVIPLLSVNMGGE ENSP00000364956/1-1019 CSPPEGTITKEGMLHYKAGTSYLGKEHWKTCFVVLSNGILYQYPDRTDVIPLLSVNMGGE ENSMUSP00000081221/1-1033 CSPAEGTITKEGMLHYKASTSYLGKEHWKACFVVLSNGILYQYPDRTDVIPLLSVNMGGE ENSRNOP00000016333/1-1031 CSPAEGTITKEGMLHYKASTSYLGKEHWKACFVVLSNGILYQYPDRTDVIPLLSVNMGGE *** **:*****:*****.**********:****************************** ENSCPOP00000010857/1-1003 QCSGCWRSNTTDRPHAFQVILADRPCLELSAESEAEMTDWMQHLCQARSKGVIPQGVAPS XP_004850396.1/1-1006 QCGGCRRSNTTDRPHAFQVILADRPCLELSAESEAEMADWMQHLCQAVSKGVIPQGVTPS ENSP00000364956/1-1019 QCGGCRRANTTDRPHAFQVILSDRPCLELSAESEAEMAEWMQHLCQAVSKGVIPQGVAPS ENSMUSP00000081221/1-1033 QCGGCRRSNTTDRPHAFQVILADRPCLELSADSEAEMADWMQHLCQAVSKGVIPQGIAPS ENSRNOP00000016333/1-1031 QCGGCRRSNTTDRPHAFQVILADRPCLELSADSEAEMADWMQHLCQAVSKGVIPQGIAPS **.** *:*************:*********:*****::******** ********::** ENSCPOP00000010857/1-1003 PCIPCCLVITGDHLFTCHEDCQTSFFRSLGTARLADVSAVSMESGKEYCILEFSQDSLQL XP_004850396.1/1-1006 PCIPCCLVITSDHLFTCHEDCQTSFFRSLGTARLADISAISMEPGKEYCILEFSQDSPQL ENSP00000364956/1-1019 PCIPCCLVLTDDRLFTCHEDCQTSFFRSLGTAKLGDISAVSTEPGKEYCVLEFSQDSQQL ENSMUSP00000081221/1-1033 PCIPCCLVITEDRLFTCHEDCQTSFFRSLGTARLADITAISTELGKEYCVLEFSQDSPQL ENSRNOP00000016333/1-1031 PCIPCCLVITEDRLFTCHEDCQTSFFRSLGTARLADITAISTELGKEYCVLEFSQDSPQL ********:* *:*******************:*.*::*:* * *****:******* ** ENSCPOP00000010857/1-1003 PAPWVIYLSCPSELDRFLSALNSGWKAIYQVDLPHKAIREASSRQKLENALSLIHSAWQR XP_004850396.1/1-1006 PTPWVIYLSCTSELDRFLSALNSGWKAIYQVDLPQKAIHEASTRQKFEDALSLIHSAWQR ENSP00000364956/1-1019 LPPWVIYLSCTSELDRLLSALNSGWKTIYQVDLPHTAIQEASNKKKFEDALSLIHSAWQR ENSMUSP00000081221/1-1033 LQPWVIYLSCTSELDRFLTALSSGWKAIYQVDLPHKAIHEASIKQKFEDALSLIHSAWQR ENSRNOP00000016333/1-1031 PKPWVIYMSCTSELDRFLTALSSGWKAIYQVDLPHKAIHEASIKQKFEDALSLIHSAWQR *****:**.*****:*:**.****:*******:.**:*** ::*:*:*********** ENSCPOP00000010857/1-1003 SDSLCRGRASRDPWC XP_004850396.1/1-1006 SDSLCRGRASRDPWC ENSP00000364956/1-1019 SDSLCRGRASRDPWC ENSMUSP00000081221/1-1033 SDSLCRGRASRDPWC ENSRNOP00000016333/1-1031 SDSLCRGRASRDPWC ***************