CLUSTAL W(1.81) multiple sequence alignment ENSMUSP00000027027/1-887 ----MEAFSVRFESASSIEERKEQTRNARAEVLRQAKHNFEKEQRGEERKRLRDEDTWML ENSRNOP00000030298/1-888 ----MAAFGLRFESASSIEERKEQTRIARAEVLRQAKHNFEKEQRDKELKQLRGEDTWML ENSCPOP00000010851/1-886 ----MAASSGRFESAKSIEERKELCRIARAEVLRQAKANFEKEERRKELKRLRGEDTWML ENSP00000282251/1-894 MATSMAAASGRFESAKSIEERKEQTRNARAEVLRQAKANFEKEERRKELKRLRGEDTWML XP_004856551.1/1-882 ----MAASSGRFESAKSIEERKEQTRIARAEVLRQAKANFEKEERWKELKRLRGEDTWML * * . *****.******* * ********** *****:* :* *:**.****** ENSMUSP00000027027/1-887 PDVHERIEQFSQEHSEKKKKKKDKHSKKVKKEKKKKRKKQKCQKQSESTDSSASSEDEWV ENSRNOP00000030298/1-888 PDVNERIEQFAQEHSEKKKKKKNKHSKKVKKEKKKKRKKQKCQIQSESTDNSSSSEDEWV ENSCPOP00000010851/1-886 PDVSERIEEFSKEHSDTEKMNVNTEVSEGKRNKKKWSFKTSFIRNSHSSHWLNNIVLFWI ENSP00000282251/1-894 PDVNERIEQFSQEHSVKKKKKKDKHSKKAKKEKKKKSKKQKYEKNNESSDSSSSSEDEWV XP_004856551.1/1-882 PDVNEQIEQFSKEHSLKKKKKKEKHSKKEKKEKKKKSKKQKYEK-SESTDSSSSSEDEWV *** *:**:*::*** .:* : :.. .: *::*** * . ..*:. . *: ENSMUSP00000027027/1-887 EAAPSQISDKEKTWKVKDKRTEEECDSHDIQRDEWMTIDFMSIKTVSSSSLKAEKETLRQ ENSRNOP00000030298/1-888 EAAPSQIPGKEKTWKVKDKKTEKECDSQSIQHDEWMTVDFMSIKTVSSSSLKAEKETLRQ ENSCPOP00000010851/1-886 LLVEQVMRNKWIYWNIKFCETSR-YRNQLEQRDEWMTVDFMSVKTVSSSSLKTEKEMTRK ENSP00000282251/1-894 EAVPSQTPDKEKAWKVKDEKSGK-DDTQIIKRDEWMTVDFMSVKTVSSSSLKAEKETMRK XP_004856551.1/1-882 EAVPSQTPGNEKAWKAKDEKLEKEDDSQAIQRDEWMTVDFLSVKTVSSSSLKAEKEMTRK . . .: *: * . . .: ::*****:**:*:*********:*** *: ENSMUSP00000027027/1-887 IEREKTQVLEQSKLLERELNPYWKDGGTGLPSKTC-ILPVTKAKGVEDGGLSWLRKSCQR ENSRNOP00000030298/1-888 IEQEKTQALEQSKLLERELNPYWKDGGTGLPPENC-ILPVTKAGGVEDGGLSWLRKSCQR ENSCPOP00000010851/1-886 IEREKSQALEQSKLLERELNPYWKDGGTGLPSEDCGVSSLTKASGVEDGGLSWLRKSCQR ENSP00000282251/1-894 IEQEKNQALEQSKLMERELNPYWKDGGTGLPPEDCSVSSITKVSVVEDGGLSWLRKSYLR XP_004856551.1/1-882 IEREKNQALEQCKLLERELNPYWKDGGTGLPSEDCSESSV-KVSGIEDGGLSWLRKSYQR **:**.*.***.**:****************.: * .: *. :*********** * ENSMUSP00000027027/1-887 MKEQAQKENRNFEDIVAEKYGSMEIFQSKLKEAEKIAYKKEDCGWERWRKPTYSDRAQCS ENSRNOP00000030298/1-888 MKEQAQKENRNFEDIVAEKYGSMEIFQSKLKEVEKITYKREDYGQERWRKSAYSEKAQRS ENSCPOP00000010851/1-886 MREQAEKQNRKFEDIVAERYGSMEIFQLKLEEAEKTASRNEDSRQELWRKPTYSDKVQRS ENSP00000282251/1-894 MKEQAEKQSRNFEDIVAERYGSMEIFQSKLEDAEKAASTKEDYRRERWRKPTYSDKAQNC XP_004856551.1/1-882 MKEQAEKQNRKFEDIVAERYGSMEIFQLKLEEAEKTASKNQDYRQERWRKPTYSDKVQNS *:***:*:.*:*******:******** **::.** : .:* * ***.:**::.* . ENSMUSP00000027027/1-887 QASGTSDLVKCKNLSEDRHLEMEPANSSNY-KFSGPDTGKRSGTLQTCRRESALRKNQDS ENSRNOP00000030298/1-888 QASGTSDLVKCKNISEDRHMEMEPTSSSNC-KFSGPDSGKGPGTLGTCRRESAIRKSQES ENSCPOP00000010851/1-886 QETRKLDLVKYSKNSRDRYDTTEITNSSNKDKFSDNEKGKRYRSLESHRKEFSLRQNQEF ENSP00000282251/1-894 QESRESDLVKYGNSSRDRYATTDTAKNSNNEKFIGDEKDKRPGSLETCRRESNPRQNQEF XP_004856551.1/1-882 QE-KKLDLVKYNKSSRVKYDTTEIANSSNNDKFSSNEKDKRDGSLESHRREFSPRQNQEF * **** : *. :: : :..** ** . :..* :* : *:* *:.*: ENSMUSP00000027027/1-887 S--GNLRSKFLRPSDEDELSFHKR-KNFESSSSYSPLVAQASLHCDFRKLTENSEESSAS ENSRNOP00000030298/1-888 S--ENLRSKFLRPSDEDELSFHKR-RNFQSSTSHSSLVAQASLHCDFRKPTDYSEESSTS ENSCPOP00000010851/1-886 TSPGNLRPKFLKPSDDEEVSSHSKDRNFEP-SDLSTLVAQGSSQCGFRKPMENSEEKLTH ENSP00000282251/1-894 SF-GNLRAKFLRPSDDEELSFHSKGRKFEPLSSSSALVAQGSLCSGFRKPTKNSEERLTS XP_004856551.1/1-882 TTPGNLRPKFLRPSDDDELSSHSKARNFEP-SSSSTLVAQGSLQCGFQKPMENNEERLTS : ***.***:***::*:* *.: ::*:. :. *.****.* ..*:* . .** : ENSMUSP00000027027/1-887 CSRSDRRQENRKPSDKKPLETWSYNANQHSTGGRREQLQAESMSCDPPGRGLQQDMTLTI ENSRNOP00000030298/1-888 WSRSDGR-EDRKPSDQKSLETWSCSTNEDSIRDRREQLQSERERHDPPARGQLQDIMLTV ENSCPOP00000010851/1-886 WSQSDGG-GDKKHSSKKPLETSRSVDYQHVSGDTEEKLPVKSVKK------HGQDTESTV ENSP00000282251/1-894 WSRSDGR-GDKKHSNQKPSETST-DEHQHVPEDPREKSQDEVLRDDPPKKEHLRDTKSTF XP_004856551.1/1-882 WSRSDGR-GDKKHSSKKPLDTSSGVDSRHIPGDVGEKLPAENVRDDPP--------KSTF *:** ::* *.:*. :* .. . *: : *. ENSMUSP00000027027/1-887 AG-PEAESTYILNVDEKNKLGAKIIKAEMMGNMELAEQLKAQLKEANKFKET--QMPAKR ENSRNOP00000030298/1-888 AG-PKTEPIYPLNADEKNKLGAKIIKAEMMGNMELAEQLKAQLKEANKFKETIRQIPAKR ENSCPOP00000010851/1-886 PGIPENESIRVLSVDEKNKLGAKIIKAEMMGNMELAEQLKAQLEKANKIKDTVTQISSKT ENSP00000282251/1-894 AGSPERESIHILSVDEKNKLGAKIIKAEMMGNMELAEQLKVQLEKANKFKETITQIPKKS XP_004856551.1/1-882 TGSPEDESIHVLSVDEKNKLGAKIIKAEMMGNMELAVKLKAQLEKANKLKETVTQISSKT .* *: *. *..********************** :**.**::***:*:* *:. * ENSMUSP00000027027/1-887 L-GVEHEDEQEVILIQTDKSGRMWPVSSPRETLDMKAERRKRKRVSTHEDKERVRYFPDD ENSRNOP00000030298/1-888 S-GVEHEDEQEVILTRTDESGRVWPVSSPRETLDMKEERRKRQRASTHEDKERIRYFPDD ENSCPOP00000010851/1-886 TGAEETADQEEVILVRTDASGRVWPVTTP-EPLESKAGSRKRHRVSTHEEKQRVRYFHDD ENSP00000282251/1-894 --GVENEDQQEVILVRTDQSGRVWPVNTPGKSLESQGGRRKRQMVSTHEERERVRYFHDD XP_004856551.1/1-882 TGAEENVDQQEVILVRTDESGRVWPVNTT-QPLESKTGSRKRHRVSTHEEKERVRYFHDD . * *::**** :** ***:***.:. :.*: : ***: .****:::*:*** ** ENSMUSP00000027027/1-887 DHLSLKDLVKNEKIGTDINQNRLFMKMASKFMGKSDEDNYTLDDMFVSKAAEKEHLGKKE ENSRNOP00000030298/1-888 DHLSLNDLVRNEKMGTDIDQNRLFMKMASKFMGKSHGDYCTLDDMFVSKAAEKEHPGKKE ENSCPOP00000010851/1-886 DHLSLNDLVKNEKMGTAESQNKLFMRMASKFMGKADGDYYTLDDMFVSKAAEGECFGEEE ENSP00000282251/1-894 DNLSLNDLVKNEKMGTAENQNKLFMRMASKFMGKTDGDYYTLDDMFVSKAAERERLGEEE XP_004856551.1/1-882 DHLSLNDLVKNEKMGTAESQNKLFMRMASKFMGKADGDYYTLDDMFVSKAAEREHLGEEE *:***:***:***:** .**:***:********:. * ************ * *::* ENSMUSP00000027027/1-887 ESQRRRAIAEHQSLAAKMAKCLYCFDSSQFPKHLIVAIGVKVYLCLPSFQSLTEGHCFIV ENSRNOP00000030298/1-888 ESQRRRAIAEHQVLAAQMAKCLYCLDSSQFPKHLIVAIGVKVYLCLPNSRSLTEGHCLIV ENSCPOP00000010851/1-886 QNLRKKAVAEHQRLAAQMEKCLYCFDSSQFPKHLIVAIGVKVYLCLPNFRSLTEGHCLIV ENSP00000282251/1-894 ENQRKKAIAEHRSLAAQMEKCLYCFDSSQFPKHLIVAIGVKVYLCLPNVRSLTEGHCLIV XP_004856551.1/1-882 QNQRKKAIAEHQRLAAQMEKCLYCFDSSQFPKHLIVAIGIKVYLCLPNFQSLFEGHCLIV :. *::*:***: ***:* *****:**************:*******. :** ****:** ENSMUSP00000027027/1-887 PLQHHQAATVLDEDVWEEIQMFRKSLVKMFEDKELDCIFLETNMGLKKHYHMVYECIPLP ENSRNOP00000030298/1-888 PLQHHQAATVLDEDIWEEIQMFRKSLVKMFEDKELKCIFLETSMGLKKQYHMVYECIPLP ENSCPOP00000010851/1-886 PLQHHRAATLLDEDIWEEIQMFRKSLVKMFEDKGLDCVFLETNMSMKKHYHMVYECIPLP ENSP00000282251/1-894 PLQHHRAATLLDEDIWEEIQMFRKSLVKMFEDKGLDCIFLETNMSMKKQYHMVYECIPLP XP_004856551.1/1-882 PLQHHRAATLLDEDIWEEIQMFRKSLVKMFEDKGLDCIFLETNMNMKKQYHMVYECIPLP *****:***:****:****************** *.*:****.*.:**:*********** ENSMUSP00000027027/1-887 KEVGDMAPIYFKKAIMESDEEWSMNKKLIDLSSKDIRKSVPRGLPYFAVDFGLQGGFAHI ENSRNOP00000030298/1-888 KEVGDMAPIYFKKAIMESDEEWSMNKKLIDLSSKDIRKSVPRGLPYFAVDFGLQGGFAHI ENSCPOP00000010851/1-886 KEVGDMAPVYFKKAIMESDEEWSMNKKLIDLSSKDIRKSVPRGLPYFSVDFGLQGGFAHV ENSP00000282251/1-894 KEVGDMAPIYFKKAIMESDEEWSMNKKLIDLSSKDIRKSVPRGLPYFSVDFGLHGGFAHV XP_004856551.1/1-882 KEVGDMAPVYFKKAIMESDEEWSMNKKLIDLSSKDIRKSVPRGLPYFSVDFGLQGGFAHV ********:**************************************:*****:*****: ENSMUSP00000027027/1-887 IEDQYRFPHYFGKEIIGGMLDLEPRLWRKGIRESFEDQRKKSLQFAQWWKPYDITKSKSS ENSRNOP00000030298/1-888 IEDQYKFPHYFGKEVIGGMLDLEPRLWRNGIRESFEDQRKKVLQFAQWWKPYDVTKSKSI ENSCPOP00000010851/1-886 IEDQHKFPHYFGKEIIGGMLDLEPRLWRKGIQENFEDQRKKALQFAQWWKPYDFTKSKKC ENSP00000282251/1-894 IEDQHKFPHYFGKEIIGGMLDIEPRLWRKGIRESFEDQRKKALQFAQWWKPYDFTKSKNY XP_004856551.1/1-882 IEDQHKFPHYFGKEIIGGMLDLEPRLWRKGIRESFEDQRKKALQFAQWWKPYDFTKSKKC ****::********:******:******:**:*.******* ***********.****.