CLUSTAL W(1.81) multiple sequence alignment ENSCPOP00000010848/1-778 MEVKKLSISWQFLIVLVLILQFLSALDFDPYRVLGVSRTASQADIKKAYKKLAREWHPDK XP_004850393.1/1-780 MEVKKLTLSWQFLIVLVLILQILTALDFDPYRVLGVSRTASQADIKKAYKKLAREWHPDK ENSP00000365007/1-782 MEVRKLSISWQFLIVLVLILQILSALDFDPYRVLGVSRTASQADIKKAYKKLAREWHPDK ENSMUSP00000048714/1-772 MELKRLGVSWRFLMVLVLILQSLSALDFDPYRVLGVSRTASQADIKKAYKKLAREWHPDK ENSRNOP00000017247/1-771 MELKRLSISWQFLIVLVLILQSLSALDFDPYRVLGVSRTASQADIKKAYKKLAREWHPDK **:::* :**:**:******* *:************************************ ENSCPOP00000010848/1-778 NRDPGAADKFIQISKAYEILSNEEKRSSYDRYGDAGENQ----QQQQREYRFRHFHENFY XP_004850393.1/1-780 NRNPGAADKFIQISKAYEILSNEEKRSNYDHYGDAGENQRH--QQQQREYRFHHFHENFY ENSP00000365007/1-782 NKDPGAEDKFIQISKAYEILSNEEKRSNYDQYGDAGENQGYQKQQQQREYRFRHFHENFY ENSMUSP00000048714/1-772 NKDPGAEDRFIQISKAYEILSNEEKRTNYDHYGDAGENQGY--QKQQREHRFRHFHENFY ENSRNOP00000017247/1-771 NKDPGAEDKFIQISKAYEILSNEEKRTNYDHYGDAGENQGY---QQQREYRFRHFHENFY *::*** *:*****************:.**:******** :****:**:******* ENSCPOP00000010848/1-778 FDESFFHFPFNSEQRDSIDEKYLLHFSHYVNEVVPDSFKKPYLIKITSDWCFSCIHIEPI XP_004850393.1/1-780 FDESFFHFPFNSERRDSIDEKYLLHFSHYVNEVVPDSFKKPYLIKITSDWCFSCIHIEPI ENSP00000365007/1-782 FDESFFHFPFNSERRDSIDEKYLLHFSHYVNEVVPDSFKKPYLIKITSDWCFSCIHIEPV ENSMUSP00000048714/1-772 FDESFFHFPFNAERRDSGDEKYLLHFSHYVNEVLPESFKRPYLIKITSDWCFSCIHIEPV ENSRNOP00000017247/1-771 FDESFFHFPFNSERRDSIDEKYLLHFSHYVNEVVPDSFKKPYLIKITSDWCFSCIHIEPI ***********:*:*** ***************:*:***:*******************: ENSCPOP00000010848/1-778 WKEVVQELEGLGVGIGVVHAGYERRLAHHLGAHSTPSILGIVNGKVSFFHNAVVRENLRQ XP_004850393.1/1-780 WKEVVQELEGLGVGIGVVHAGYERRLAHHLGAHSTPSILGIINGKISFFHNAVVQENLRQ ENSP00000365007/1-782 WKEVIQELEELGVGIGVVHAGYERRLAHHLGAHSTPSILGIINGKISFFHNAVVRENLRQ ENSMUSP00000048714/1-772 WKEVVQELEGLGVGIGVVHAGYERRLAHHLGAHSTPSILGVISGKITFFHNAVVHENLRQ ENSRNOP00000017247/1-771 WKEVVQELEGLGVGIGVVHAGYERRLAHHLGAHSTPSILGIINGKISFFHNAVVHENLRQ ****:**** ******************************::.**::*******:***** ENSCPOP00000010848/1-778 FVESLLPGNLVEKVTNKNYVRFLSGWQQENKPHVLLFDQGPSVPLLYKLTAFAHKDYLSF XP_004850393.1/1-780 FVESLLPGSLVEKVTSKNYVRFLSGWQKENKPHVLLFDQGPSVPLLYKLTAFAYKDYLSF ENSP00000365007/1-782 FVESLLPGNLVEKVTNKNYVRFLSGWQQENKPHVLLFDQTPIVPLLYKLTAFAYKDYLSF ENSMUSP00000048714/1-772 FVESLLPGNLVEKVTNKNYVRFLSGWQQENKPHALLFGQTPAVPLMYKLTAFAYKDYVSF ENSRNOP00000017247/1-771 FVESLLPGNLVEKVTNKNYVRFLSGWQQENKPHALLFGQTPAAPLLYKLTAFAYKDYVSF ********.******.***********:*****.***.* * .**:*******:***:** ENSCPOP00000010848/1-778 GYANVGVRGAEEMTRQYNINVYVPTILVFKEHINKPADVMQARGLKRQLVDNFITQNKYL XP_004850393.1/1-780 GYVSFRRRGAEEMTRQYNINVYAAAILVFKEHITKPADMIQAQSLKKQVMDDFITQNKYL ENSP00000365007/1-782 GYVYVGLRGTEEMTRRYNINIYAPTLLVFKEHINRPADVIQARGMKKQIIDDFITRNKYL ENSMUSP00000048714/1-772 GYVYVGLRGVEEMTRQYNVNLYTPTMLIFKEHINKPADVIQARGLKKQVIEDFIAQNKYL ENSRNOP00000017247/1-771 GYVYVGLRGVEEMTRQYNVNIYAPTMLIFKEHINKPADAIQARGLKKQVIEDFITQNKYL **. . **.*****:**:*:*..::*:*****.:*** :**:.:*:*::::**::**** ENSCPOP00000010848/1-778 MAARLTSQKLFHELCPVKRSHRQRKYCVVLLTPEATKLSKAFEAFLSFALANTQDTVRFV XP_004850393.1/1-780 LAARLTSQKLFHELCPVKRSHRQRKYCVVLLTPEATKLSKPFEAFLSFALANTRDTVRFV ENSP00000365007/1-782 LAARLTSQKLFHELCPVKRSHRQRKYCVVLLTAETTKLSKPFEAFLSFALANTQDTVRFV ENSMUSP00000048714/1-772 LASRLTSQRLFHELCPVKRSHRQRKYCVVLLTAETNKVSKPFEAFLSFALANTQDTVRFV ENSRNOP00000017247/1-771 LASRLTSQKLFHELCPVKRSHRQRKYCVVLLTAEANKLSKPFDAFLSFALANTQDTVRFV :*:*****:***********************.*:.*:**.*:**********:****** ENSCPOP00000010848/1-778 HVYSSRQPEFASTLLPHSEAFQGNSAVSILERRNTAGRVVYKTLAEPWTGSKSDKFILLG XP_004850393.1/1-780 HVYSSRQQEFASTLLPHSEAFQGKSAVSVLERRNTAGRVVYRTLEEPWTGSESNKFILLG ENSP00000365007/1-782 HVYSNRQQEFADTLLPDSEAFQGKSAVSILERRNTAGRVVYKTLEDPWIGSESDKFILLG ENSMUSP00000048714/1-772 HVYSNRQQEFASTLLPDMEAFQGKSGVSILERRNTAGRVVFKTLEDPWTGSESDKFVLLG ENSRNOP00000017247/1-771 HVYSSRQQEFASTLLPDIEAFQGKSGVSILERRNTAGRVVFKTLEDPWTGSESDKFVLLG ****.** ***.****. *****:*.**:***********::** :** **:*:**:*** ENSCPOP00000010848/1-778 LLDQLRTDPGLLASEAVLPDLTDELAPIFLLRWLYSASDYLTDCWETMIHSNWREMMPLL XP_004850393.1/1-780 FLDQLRKDPGLLASEAVLPDLTDELAPVFLLRWLYSASDYLADCWDIMFHSNWREMMPFL ENSP00000365007/1-782 YLDQLRKDPALLSSEAVLPDLTDELAPVFLLRWFYSASDYISDCWDSIFHNNWREMMPLL ENSMUSP00000048714/1-772 YLDQLRKDPAFLSSEAVLPDLTDELAPVFFLRWLYSVSDYLSDFWESLLHSNWREMMPLL ENSRNOP00000017247/1-771 YLDQLRKDPAFLSSEAVLPDLTDELAPVFLLRWLYSVSDYLSDFWESLLHSNWREMMPLL *****.**.:*:**************:*:***:**.***::* *: ::*.*******:* ENSCPOP00000010848/1-778 SLIFSALFILFGTVIVQAFSDSSDERESHPPEKEEVPEKTGKTEPSFTKESSSKIPKKGF XP_004850393.1/1-780 SLIFSALFILFGTVIIQAFSDSSDERESHPPDKEEIPEKAGKTEPSFTKESSSKIPKKGF ENSP00000365007/1-782 SLIFSALFILFGTVIVQAFSDSNDERESSPPEKEEAQEKTGKTEPSFTKENSSKIPKKGF ENSMUSP00000048714/1-772 SLIFSALFILFGTVMVQAFSDSNEERESHPADKEEVPEKAGKTEPSFTKESSSKIPKKGF ENSRNOP00000017247/1-771 SLIFSALFILFGTVIVQAFSDSNEERESHPPDKEEVPEKAGKTEPSFTKESSSKIPKKGF **************::******.:**** *.:*** **:**********.********* ENSCPOP00000010848/1-778 VEVTELTDVTYTSNLVRLRPGHMNVVLILSNSTRSVLLQKFAFEVYTFTGSSCLHFSFLS XP_004850393.1/1-780 VEVTELTDVTYTSNLVRLRPGHMNVVLILSNSTRSVLLQKFAFEVYTFTGSSCLHFSFLS ENSP00000365007/1-782 VEVTELTDVTYTSNLVRLRPGHMNVVLILSNSTKTSLLQKFALEVYTFTGSSCLHFSFLS ENSMUSP00000048714/1-772 VEVTELTDVTYTSNLVRLRPGHMNVVLILSNSTKTSLLQKFALEVYTFTGSSSLHFSFLT ENSRNOP00000017247/1-771 VEVTELTDVTYTSNLVRLRPGHMNVVLILSNSTKTSLLQKFALEVYTFTGSSSLHFSFLT *********************************:: ******:*********.******: ENSCPOP00000010848/1-778 LDKHREWLEYLLEFAQDAAPIPNQYDKHFMERDYTGYVLALNGHKKYFCLFKPQKTVEEE XP_004850393.1/1-780 LDKHREWLEYLLEFAQDAALIPNQYDKHFMERDYTGYVLALNGHKKYFCLFKPQKTVEEE ENSP00000365007/1-782 LDKHREWLEYLLEFAQDAAPIPNQYDKHFMERDYTGYVLALNGHKKYFCLFKPQKTVEEE ENSMUSP00000048714/1-772 LDKHREWLEYLLEFAQDAAPIPNQYDKHFMERDYTGYVLALNGHKKYFCLFKPLKTV-DE ENSRNOP00000017247/1-771 LDKHREWLEYLLEFAQDAAPIPNQYDKHFMERDYTGYVLALNGHKKYFCLFKPLKTV-DE ******************* ********************************* *** :* ENSCPOP00000010848/1-778 ETMGSCGDLDASLHPGEARGKPLGGPGPRPIKGKLSKLSLWMERLLEGSLQRFYIPSWPE XP_004850393.1/1-780 EAMGSCGDLDSSLHLGEARGKPSGGPGPRPIKGKLSKLSLWMERLLEGSLQRFYIPSWPE ENSP00000365007/1-782 EAIGSCSDVDSSLYLGESRGKPSCGLGSRPIKGKLSKLSLWMERLLEGSLQRFYIPSWPE ENSMUSP00000048714/1-772 ETVASC-DPDSS------RGKPSCGLGPKPLKGKLSKLSLWMERLLEGSLQRFYIPSWPE ENSRNOP00000017247/1-771 ETVGSC-DLDSS------RGKPPCGLGPKPLKGKLSKLSLWMERLLEGSLQRFYIPSWPE *::.** * *:* **** * *.:*:***************************** ENSCPOP00000010848/1-778 LD XP_004850393.1/1-780 LD ENSP00000365007/1-782 LD ENSMUSP00000048714/1-772 LD ENSRNOP00000017247/1-771 LD **