CLUSTAL W(1.81) multiple sequence alignment ENSP00000394114/1-586 MERDSHGNASPARTPSAGASPAQASPAGTPPGRASPAQASPAQASPAGTPPGRASPAQAS ENSMUSP00000034597/1-548 MDRGSHRNSSPARTPP-QASPA----------RTSPARA-PPQASPARTPP------QAS ENSRNOP00000021949/1-539 MDRGSHRNASPARPSP-QASPA----------RASP-QASPARTPPPQASPARASPPQAS ENSCPOP00000010740/1-509 -------NASPAWTTPAQASPA----------RTPPAQASPPRTSPAQAPS--------- XP_004856738.1/1-520 MERDSCWNTSPARTPPAQASPA----------RTPPAQASPARTPPAQVSPARTPPAQAS *:*** ... **** *:.* :* *.::.*. ... ENSP00000394114/1-586 PAGTPPGRASPGRASPAQASPAQASPARASPALASLSRSSSGRSSSARSASVTTSPTRVY ENSMUSP00000034597/1-548 PTRTPP-QASPARAPPPQASPARASPARASLARAPPSRSSSGRSSSARSASTTSSPTRVY ENSRNOP00000021949/1-539 PAR---------------ASPARASPVRASPARAPPSRSSSGRSSSARSASTTSSPTRVY ENSCPOP00000010740/1-509 -------------------------------TRKSPSRSSSNKSSSAKSASMTSSPTKAY XP_004856738.1/1-520 PARTPPAQVSPARTSSAQASPARTSPAPTSSTRKSPSRSSSSRSS-AKSASTTSSPTKAY : . *****.:** *:*** *:***:.* ENSP00000394114/1-586 LVRATPVGAVPIRSSPARSAPATRATRESPGTSLPKFTWREGQKQLPLIGCVLLLIALVV ENSMUSP00000034597/1-548 LVRATPVGAVPIRASPARSAPATRATRESPGLSFPKFSWQETQRQLPLIGCVILLISLVI ENSRNOP00000021949/1-539 LVRAIPVGTV-IRASPARSAPATRATRESPGLSFPKFSWQETQRQLPLIGCVLLLISLVI ENSCPOP00000010740/1-509 LVRAKPV-VIPIRASPARSAAATSTNRQSLGFGLPKISWQECKKQLPLIGCVLLLIALVI XP_004856738.1/1-520 LVRATPV-AVPIQASPARSATAARTTRQR------------------------------- **** ** .: *::******.*: :.*: ENSP00000394114/1-586 SLIILFQFWQGHTGIRYKEQRESCPKHAVRCDGVVDCKLKSDELGCVRFDWDKSLLKIYS ENSMUSP00000034597/1-548 SLILLFYFWRGHTGIKYKEPLESCPIHAVRCDGVVDCKMKSDELGCVRFDWDKSLLKVYS ENSRNOP00000021949/1-539 SLILLFYFWRGHTGIKYKEPLESCPKHAVRCDGVVDCKMKSDELGCVRFDWDKSLLKVYS ENSCPOP00000010740/1-509 SLIVLFYFWQGHTGIKYKEAVESCPIHAVRCDGVTDCKLRSDELGCVRFDWDTSLLKVYS XP_004856738.1/1-520 ----LVFFWQGHTGIKYKEAVESCPIHAVRCDGVLDCKLRSDELGCVRFDWDKSLLKVYS *. **:*****:*** **** ******** ***::************.****:** ENSP00000394114/1-586 GSSHQWLPICSSNWNDSYSEKTCQQLGFESAHRTTEVAHRDFANSFSILRYNSTIQESLH ENSMUSP00000034597/1-548 GSSGEWLPVCSSSWNDTDSKRTCQQLGFDSAYRTTEVAHRDITSSFLLSEYNTTIQESLY ENSRNOP00000021949/1-539 GSSGEWLPVCSSSWNDTDSERTCQQLGFDSAYRTTEVAHRDVTSSFLLSEYNSTIQESLT ENSCPOP00000010740/1-509 GTSREWLPICSSSWNDSDSQKTCQQLGFESAYRTTEVAHGDFASSFSISEFNSTIQESLY XP_004856738.1/1-520 GSSHEWLPICSSSWNDSDSQKTCQQLGFESAYRTAEVAHRDFSSSFSISEYNSTIQESLH *:* :***:***.***: *::*******:**:**:**** *.:.** : .:*:****** ENSP00000394114/1-586 RSECPSQRYISLQCSHCGLRAMTGRIVGGALASDSKWPWQVSLHFGTTHICGGTLIDAQW ENSMUSP00000034597/1-548 RSQCPSRRYVSLQCSHCGLRAMTGRIVGGALTSESKWPWQVSLHFGTTHICGGTLIDAQW ENSRNOP00000021949/1-539 RSECPSRRYVSLQCAHCGLRAMTGRIVGGALTSESKWPWQVSLHFGTTHICGGTLIDAQW ENSCPOP00000010740/1-509 RSQCPSQRYVSLQCSHCGLRAMTGRIVGGVLASGSKWPWQVSLHYGTTHICGGTLIDPQW XP_004856738.1/1-520 RSECPSQRYVSLQCSHCGLRAMTGRIVGGVLTSGSKWPWQVSLHYGTTHICGGTLIDPQW **:***:**:****:**************.*:* **********:************.** ENSP00000394114/1-586 VLTAAHCFFVTREKVLEGWKVYAGTSNLHQLPEAASIAEIIINSNYTDEEDDYDIALMRL ENSMUSP00000034597/1-548 VLTAAHCFFVTREKLLEGWKVYAGTSNLHQLPEAASISQIIINGNYTDEQDDYDIALIRL ENSRNOP00000021949/1-539 VLTAAHCFFVTREKILEGWKVYAGTSNLHQLPEAASISQIIINGNYTDEQDDYDIALVRL ENSCPOP00000010740/1-509 VLTAAHCFFVTREKMLEGWKVYAGTNNLHQLPEAASIAQIIINSNYTDEQDDYDIALMRL XP_004856738.1/1-520 VLTAAHCFFVTREKMLEGWKVYVGTNNLKQLPEAASIAQIIINSNYTDEQDDYDIALMRL **************:*******.**.**:********::****.*****:*******:** ENSP00000394114/1-586 SKPLTLSAHIHPACLPMHGQTFSLNETCWITGFGKTRETDDKTSPFLREVQVNLIDFKKC ENSMUSP00000034597/1-548 SKPLTLSAHIHPACLPMHGQTFGLNETCWITGFGKTKETDEKTSPFLREVQVNLIDFKKC ENSRNOP00000021949/1-539 SKPLTLSAHIHPACLPLHGQTFGLNETCWITGFGKTKETDEKTSPFLREVQVNLIDFKKC ENSCPOP00000010740/1-509 SKPLTLSTHIHPVCLPMHGQTFSLNETCWITGFGKTKETDEKTSPFLREVQVNLIDFNKC XP_004856738.1/1-520 SKPLTLSTHIHPVCLPMHGQTFSLNKTCWITGFGKTKETDEKTSPFLREVQVNLIDFKEC *******:****.***:*****.**:**********:***:****************::* ENSP00000394114/1-586 NDYLVYDSYLTPRMMCAGDLRGGRDSCQGDSGGPLVCEQNNRWYLAGVTSWGTGCGQRNK ENSMUSP00000034597/1-548 NDYLVYDSYLTPRMMCAGDLRGGRDSCQGDSGGPLVCEQNNRWYLAGVTSWGTGCGQKNK ENSRNOP00000021949/1-539 NDYLVYDSYLTPRMMCAGDLRGGRDSCQGDSGGPLVCEQNNRWYLAGVTSWGTGCGQKNK ENSCPOP00000010740/1-509 NSYSVYDNYLTPRMMCAGDLAGGRDSCQGDSGGPLVCEQKNRWYLAGVTSWGTGCGQRNK XP_004856738.1/1-520 NDYLVYDNYLTPRMMCAGDLRGGRDSCQGDSGGPLVCEQNNRWYLAGVTSWGTGCGQRNK *.* ***.************ ******************:*****************:** ENSP00000394114/1-586 PGVYTKVTEVLPWIYSKMEVRSLQQDTAPSRLGTSSGGDPGGAPRL ENSMUSP00000034597/1-548 PGVYTKVTEVLPWIYRKME--------SEVRFRKS----------- ENSRNOP00000021949/1-539 PGVYTKVTEVLPWIYRKME--------SEVRFRKS----------- ENSCPOP00000010740/1-509 PGVYTKVSEVLPWIYSKME--------SEVRFQKS----------- XP_004856738.1/1-520 PGVYTKVSEVLPWIYTKME--------SEVRFRKS----------- *******:******* *** : *: .*