CLUSTAL W(1.81) multiple sequence alignment ENSMUSP00000005431/1-738 MASILLRSCRGRGPARLAP-PRAASPRGSLRDRACLSCTRTLGLTSRESVLSRCCTPAHP ENSRNOP00000022540/1-739 MASILLRSCRGRGPARLAS-PRAASPRGSLRDRACLSCTRTVGLTSHESVLSRCCTPANP ENSP00000305653/1-739 MASILLRSCRGRAPARLPPPPRYTVPRGSPGDPAHLSCASTLGLRNCLNVPFGCCTPIHP ENSCPOP00000010193/1-706 MASILLRR-KGEAQLAAGP--ASTPRRGSLGHRACLSCTSTVGLRSRVIVPSGCCALARP XP_004847465.1/1-738 MASILLRSCRGRAPVRLPP-PGSAAPRGLPGEP-HAGCASLLGLVFVLTVPSGCCAPAHP ******* :*.. . : ** . .*: :** * **: .* ENSMUSP00000005431/1-738 VYLCFKGEPLSCWTQRPECQGTAARTTWTPASARLVVTGPQYLPVRGWHSSSPLGEDSVI ENSRNOP00000022540/1-739 VYLYFKSEPLSCWTQRPECQGTVARAAWTPASARLVVTGPQYLPVRGWHSSSPLGEDSMI ENSP00000305653/1-739 VYTSSRGDHLGCWALRPECLRIVSRAPWTSTSVGFVAVGPQCLPVRGWHSSRPVRDDSVV ENSCPOP00000010193/1-706 LHLC-------CWTPRPEYLCMVVAAPWGPAAMAVLVGRPCYLPMRGWHSSPPLHDDSVV XP_004847465.1/1-738 LYLYLRVEPCGHWTLRPERLCMVAGAPWTPTAVGVVVGGPRYLPVRGWHSSPCLSDDSVV :: *: *** . :.* .:: .:. * **:****** : :**:: ENSMUSP00000005431/1-738 EKSLKSLKDKNKKLEEGGPVYSPPAQVVVRKSLGQKVLDELRHYYHGFRLLWIDTKIAAR ENSRNOP00000022540/1-739 EKSLKSLKDKNKKLEEGGPVYSPPAQVVVKKSLGQKILDELKHYYHGFRLLWIDTKIAAR ENSP00000305653/1-739 EKSLKSLKDKNKKLEEGGPVYSPPAEVVVKKSLGQRVLDELKHYYHGFRLLWIDTKIAAR ENSCPOP00000010193/1-706 EKSLKSLKDKNKKLEEGGPVYSPATPAAVRRSLGQRVLDELRHYYHGFRLLWIDTKIAAR XP_004847465.1/1-738 EKSLKSLKDKNKKLEEGGPVYSPAAPVAVKKSLGQRVLDELKHYYHGFRLLWIDTKIAAR ***********************.: ..*::****::****:****************** ENSMUSP00000005431/1-738 MLWRILNGHTLTRRERRQFLRICADLFRLVPFLVFVVVPFMEFLLPVVVKLFPNMLPSTF ENSRNOP00000022540/1-739 MLWRILNGHTLTRRERRQFLRICADLFRLVPFLVFVVVPFMEFLLPVVVKLFPNMLPSTF ENSP00000305653/1-739 MLWRILNGHSLTRRERRQFLRICADLFRLVPFLVFVVVPFMEFLLPVAVKLFPNMLPSTF ENSCPOP00000010193/1-706 TLWRILHGHTLTRRERRQFLRICADLFRLVPFLVFVVVPFMEFLLPVAVKLFPNMLPSTF XP_004847465.1/1-738 MLWRILHGHALTRRERRQFLRICADLFRLVPFLVFVVVPFMEFLLPVAVKLFPNMLPSTF *****:**:*************************************.************ ENSMUSP00000005431/1-738 ETQSIKEERLKKELRVKLELAKFLQDTIEEMALKNKAAKGNATKDFSAFFQKIRETGERP ENSRNOP00000022540/1-739 ETQSIKEERLKKELRVKLELAKFLQDTIEEMALKNKAAKGNATKDFSAFFQKIRETGERP ENSP00000305653/1-739 ETQSLKEERLKKELRVKLELAKFLQDTIEEMALKNKAAKGSATKDFSVFFQKIRETGERP ENSCPOP00000010193/1-706 ETQSIKEERLKKELRVKLELAKFLQDTIEEMALKNKAAKGSATQDFSAFFQKIRETGERP XP_004847465.1/1-738 ETQSIKEERLKKELRVKLELAKFLQDTIEEMALKNKAAKGSATQDFSVFFQKIRETGERP ****:***********************************.**:***.************ ENSMUSP00000005431/1-738 SNEEIMRFSKLFEDELTLDNLTRPQLVALCKLLELQSIGTNNFLRFQLTMRLRSIKADDK ENSRNOP00000022540/1-739 SNEEIMRFSKLFEDELTLDNLTRPQLVALCKLLELQSIGTNNFLRFQLTMRLRSIKADDK ENSP00000305653/1-739 SNEEIMRFSKLFEDELTLDNLTRPQLVALCKLLELQSIGTNNFLRFQLTMRLRSIKADDK ENSCPOP00000010193/1-706 SNEEIMRFSKLFEDELTLDNLTRPQLVALCKLLELQSIGTNNFLRFQLTMRLRSIKADDK XP_004847465.1/1-738 SNEEIMRFSKLFEDELTLDNLTRPQLVALCKLLELQSIGTNNFLRFQLTMRLRSIKADDK ************************************************************ ENSMUSP00000005431/1-738 LISEEGVDSLTVKELQAACRARGMRALGVTEDRLKGQLKQWLDLHLHHEIPTSLLILSRA ENSRNOP00000022540/1-739 LISEEGVDSLTVKELQAACRARGMRALGVTEDRLKGQLKQWLDLHLYHEIPTSLLILSRA ENSP00000305653/1-739 LIAEEGVDSLNVKELQAACRARGMRALGVTEDRLRGQLKQWLDLHLHQEIPTSLLILSRA ENSCPOP00000010193/1-706 LIAEEGVDTLNVKELQAACRARGMRALGVTEDRLRSQLKQWLDLHLHQEVPTSLLVLSRA XP_004847465.1/1-738 LIAEEGVDSLNVKELQAACRARGMRALGVTEDRLRSQLKQWLDLHLHQEVPTSLLVLSRA **:*****:*.***********************:.**********::*:*****:**** ENSMUSP00000005431/1-738 MYLPDTLSPADQLKSTLQTLPEIVAKEAQVKVAEVEGEKVDNKAKLEATLQEEAAIQQEH ENSRNOP00000022540/1-739 MYLPDTLSPADQLKSTLQTLPEIVAKEAQVKAAEVEGEQVDNKAKLEATLQEEAAIQQEH ENSP00000305653/1-739 MYLPDTLSPADQLKSTLQTLPEIVAKEAQVKVAEVEGEQVDNKAKLEATLQEEAAIQQEH ENSCPOP00000010193/1-706 MYLPDTLSPADQIKSTLQTLPEIVAKEAQVKAAEVEGEQVDNKAKLEATLQEEAAIQQEH XP_004847465.1/1-738 MYLPDTLSPADQLKSTLQTLPEIVAKEAQVKAAEVEGEQVDNKAKLEATLQEEAAIRQEH ************:******************.******:*****************:*** ENSMUSP00000005431/1-738 LE-ELKRASEAVKDIQPEVAEATLPGRPGPEPQPPVDDVILPSEVLTDTAPVLEGLKGEE ENSRNOP00000022540/1-739 LE-ELKRAAETAKDIQPEVAEATVPGRPGAELQPKMVDVIPPSEILKDTAPVLEGLKGEE ENSP00000305653/1-739 REKELQKRSEVAKDFEPERV-VAAPQRPGTEPQPEMPDTVLQSETLKDTAPVLEGLKEEE ENSCPOP00000010193/1-706 HEKELQRAAEAQKGTELEGVGATTLGKPIAEPQLEVPDVILPSVVLKDTAPVLEGLKEEE XP_004847465.1/1-738 HEKELQRAAEVEKGAELEGVGATTPEKPVAELRPEMPDVILPSEALKDTAPVLEGLKEEE * **:: :*. *. : * . .: :* .* : : *.: * *.********** ** ENSMUSP00000005431/1-738 ITKEEIDILSDACSKLQEQKKSLTKEKEELELLKEDVQDYSEDLQEIKKELSKTGEEKYI ENSRNOP00000022540/1-739 ITKEEIDILSDACSKLKEQKKSLTKEKEELELLKEDVQDYSEDLQEIKKELSKTGDEKYI ENSP00000305653/1-739 ITKEEIDILSDACSKLQEQKKSLTKEKEELELLKEDVQDYSEDLQEIKKELSKTGEEKYV ENSCPOP00000010193/1-706 ITKEEIDILSDACSKLKEQKKSLTKEKEELELLKEDVQDYSEDLQEIKKELSKTGEEQLV XP_004847465.1/1-738 ITKEEIDVLSDACSKLKEQKKSLTKEKEELELLKEDVQDYSEDLREIKRELSKTGEDKLV *******:********:***************************:***:******::: : ENSMUSP00000005431/1-738 EESAASKRLSKRVQQMIGQIDGLITQLETTQQDGKLGP-SQSTPTGESVISITELISAMK ENSRNOP00000022540/1-739 EESTASKRLSKRVQQMIGQIDGLITQLETTQQNGKLDPAAASSPTGESVISVDELISAMK ENSP00000305653/1-739 EESKASKRLTKRVQQMIGQIDGLISQLEMDQQAGKLAP-ANGMPTGENVISVAELINAMK ENSCPOP00000010193/1-706 EESKASKRLTKRVQQMIGQIDRLIAQLEAGQQSGRLGP-AQGSPVGENVISVTELISAMK XP_004847465.1/1-738 EESKASKRLTQRVQQMIGQIDGLIAQLEAGQQTGRLGP-DESAPGGENVISVTELISAMK *** *****::********** **:*** ** *:* * . * **.***: ***.*** ENSMUSP00000005431/1-738 QIKHIPEHKLISLTSALDDNKDGNINIDDLVKVIDLVNKEDVQISTTQVAEIVATLEKEE ENSRNOP00000022540/1-739 QIKHIPEHKLISLTSALDENKDGNINIDDLVKVIDLVNKEDVQISTTQVAEIVATLEKEE ENSP00000305653/1-739 QVKHIPESKLTSLAAALDENKDGKVNIDDLVKVIELVDKEDVHISTSQVAEIVATLEKEE ENSCPOP00000010193/1-706 QVKHIPENKLVSLASALDENKDGKINIDDLVKVIELVDKEDVHISTSQVAEIVATLE--- XP_004847465.1/1-738 QIKHIPENKLVSLASALDENKDGKINIDDLVKVIELVDKEDIHISTSQVAEIVATLEKEE *:***** ** **::***:****::*********:**:***::***:********** ENSMUSP00000005431/1-738 KIEEKEKAKEKAEKEAAEVKN ENSRNOP00000022540/1-739 KVEEKEKAKEKAEKEAAEVKN ENSP00000305653/1-739 KVEEKEKAKEKAEKEVAEVKS ENSCPOP00000010193/1-706 --------------------- XP_004847465.1/1-738 KVGEQEKAKEKAEKEAAEVQN