CLUSTAL W(1.81) multiple sequence alignment ENSP00000340507/1-1050 MEVAVEKAVAAAAAASAAASGGPSAAPSGENEAESRQGPDSERGGEAARLNLLDTCAVCH XP_004851301.1/1-1011 MEVAVEK-----AAAPAAAAGGPSAAPSGENEAESRQGPDSERGGEASRLNLLDTCAVCH ENSCPOP00000010171/1-929 ------------------------------------------------------------ ENSRNOP00000050587/1-866 ------------------------------------------------------------ ENSMUSP00000031859/1-1051 MEVAVEK----AAAAAAPAGGPAAAAPSGENEAESRQGPDSESGGEASRLNLLDTCAVCH ENSP00000340507/1-1050 QNIQSRAPKLLPCLHSFCQRCLPAPQRYLMLPAPMLGSAETPPPVPAP----GSPVSGSS XP_004851301.1/1-1011 QNIQSRAPKLLPCLHSFCQRCLPAPHRYLMLPAPMLGAADSAPPLLAP----GSPVGGSS ENSCPOP00000010171/1-929 ------------------------------------------------------------ ENSRNOP00000050587/1-866 ------------------------------------------------------------ ENSMUSP00000031859/1-1051 QNIQSRVPKLLPCLHSFCQRCLPAPQRYLMLTAPALGSAETPPPAPAPAPAPGSPAGGPS ENSP00000340507/1-1050 PFATQVGVIRCPVCSQECAERHIIDNFFVKDTTEVPSSTVEKSNQVCTSCEDNAEANGFC XP_004851301.1/1-1011 PFAAQVGVIRCPICSQECAERHIIDNFFVKDTTEVPSSTVEKSNQVCTSCEDNAEANGFC ENSCPOP00000010171/1-929 -----VGVIRCPICSQECAERHIIDNFFVKDTTEVPSSTVEKSNQVCTSCEDNAEANGFC ENSRNOP00000050587/1-866 ------------------------------------------------------------ ENSMUSP00000031859/1-1051 PFATQVGVIRCPVCSQECAERHIIDNFFVKDTTEVPSSTVEKSNQVCTSCEDNAEANGFC ENSP00000340507/1-1050 VECVEWLCKTCIRAHQRVKFTKDHTVRQKEEVSPEAVGVTSQRPVFCPFHKKEQLKLYCE XP_004851301.1/1-1011 VECVEWLCKTCIRAHQRVKFTKDHTVRQKEEVSPEAVGVTSQRPVFCPFHKKEQLKLYCE ENSCPOP00000010171/1-929 VECVEWLCKTCIRAHQRVKFTKDHTVRQKEEVSPEAVGVTSQRPVFCPFHKKEQLKLYCE ENSRNOP00000050587/1-866 ------------------------------------------------------------ ENSMUSP00000031859/1-1051 VECVEWLCKTCIRAHQRVKFTKDHTVRQKEEVSPEAVGVTSQRPVFCPFHKKEQLKLYCE ENSP00000340507/1-1050 TCDKLTCRDCQLLEHKEHRYQFIEEAFQNQKVIIDTLITKLMEKTKYIKFTGNQIQNRII XP_004851301.1/1-1011 TCDKLTCRDCQLLEHKEHRYQFIEEAFQNQKVIIDTLITKLMEKTKYIKYTGNQIQNRII ENSCPOP00000010171/1-929 TCDKLTCRDCQLLEHKEHRYQFIEEAFQNQKVIIDTLITKLMEKTKYIKYTGNQIQNRII ENSRNOP00000050587/1-866 ------------------------------------------------------------ ENSMUSP00000031859/1-1051 TCDKLTCRDCQLLEHKEHRYQFIEEAFQNQKVIIDTLITKLMEKTKYIKYTGNQIQNRII ENSP00000340507/1-1050 EVNQNQKQVEQDIKVAIFTLMVEINKKGKALLHQLESLAKDHRMKLMQQQQEVAGLSKQL XP_004851301.1/1-1011 EVNQNQKQVEQDIKVAIFTLMVEINKKGKALLHQLESLAKDHRMKLMQQQQEVAGLSKQL ENSCPOP00000010171/1-929 EVNQNQKQVEQDIKVAIFTLMVEINKKGKALLHQLESLAKDHRMKLMQQQQEVAGLSKQL ENSRNOP00000050587/1-866 ------------------------------------------------------------ ENSMUSP00000031859/1-1051 EINQNQKQVEQDIKVAIFTLMVEINKKGKALLHQLESLAKDHRMKLMQQQQEVAGLSKQL ENSP00000340507/1-1050 EHVMHFSKWAVSSGSSTALLYSKRLITYRLRHLLRARCDASPVTNNTIQFHCDPSFWAQN XP_004851301.1/1-1011 EHVMHFSKWAVSSGSSTALLYSKRLITYRLRHLLRARCDASPVTNNIIQFHCDPSFWAQN ENSCPOP00000010171/1-929 EHVMHFSKWAVSSGSSTALLYSKRLITYRLRHLLRARCDASPVTNNTIQFHCDPSFWAQN ENSRNOP00000050587/1-866 ------------------------------------------------------------ ENSMUSP00000031859/1-1051 EHVMHFSKWAVSSGSSTALLYSKRLITYRLRHLLRARCDASPVTNTTIQFHCDPSFWAQN ENSP00000340507/1-1050 IINLGSLVIEDKESQPQMPKQNPVVEQNSQPPSGLSSNQLSKFPTQISLAQLRLQHMQQQ XP_004851301.1/1-1011 IINLGSLVIEDKESQPQMPKQNPVVEQNSQPPGGLSSNQLSKFPTQISLAQLRLQHMQQ- ENSCPOP00000010171/1-929 IINLGSLVIEDKESQPQMPKQNPVVEQNSQPPGGLSSNQLSKFPTQISLAQLRLQHMQQQ ENSRNOP00000050587/1-866 ------------------------------------------------------------ ENSMUSP00000031859/1-1051 IINLGSLVIEDKESQPQMPKQNPVVEQSSQPPGGLPSNQLSKFPTQISLAQLRLQHIQQQ ENSP00000340507/1-1050 VMAQRQQVQRRPAPVGLPNPRMQGPIQQPSISHQQPPPRLINFQNHSPKPNGPVLPPHPQ XP_004851301.1/1-1011 ---------------------------------QQPPPRLINFQNHSPKPNGPVLPPHPQ ENSCPOP00000010171/1-929 VMAQRQQVQRRPAPVGLPNPRMQGPIQQPSISHQQPPPRLINFQNHSPKPNGPVLPPHPQ ENSRNOP00000050587/1-866 -MAQRQQVQRRPAPVGSPNPRMQGPIQQPSISLQHPPPRLINFQNHSPKPNGPVLPPYPQ ENSMUSP00000031859/1-1051 VMAQRQQVQRRPAPVGLPNPRMQGPIQQPSISHQHPPPRLINFQNHSPKPNGPVLPPYPQ *:**********************:** ENSP00000340507/1-1050 QLRYPPNQNIPRQ-AIKPNPLQMAFLAQQAIKQWQISSGQGTPSTTNSTSSTPSSPTITS XP_004851301.1/1-1011 QLRYPPNQNMPRQ-AIKPNPLQMAFLAQQAIKQWQISSGQAAATTASSSSSTPSSPTITS ENSCPOP00000010171/1-929 QLRYPPNQNVPRQ-AIKPNPLQMAFLAQQAIKQWQISSGQAAASTTSSSSSTPSSPTITS ENSRNOP00000050587/1-866 QLRYPPSQNIPRQ-AIKPNPLQMAFLAQQAIKQWQISSGQATPTTASSSSSTPSSPTITS ENSMUSP00000031859/1-1051 QLRYSPSQNVPRQTTIKPNPLQMAFLAQQAIKQWQISSVQAPPTTASSSSSTPSSPTITS ****.*.**:*** :*********************** *...:*:.*:*********** ENSP00000340507/1-1050 AAGYDGKAFGSPMIDLSSPVGGSYNLPSLPDIDCSSTIMLDNIVRKDTNIDHGQPRPPSN XP_004851301.1/1-1011 AAGYDGKAFGSPMIDLSAPVGGSYNLPSLPDIDCSSTIMLDNIGRKDTSTDHGQPRPPSN ENSCPOP00000010171/1-929 AAGYDGKGFGSPMIDLSAPVGGSYNLPSLPDIDCSSTIMLDNIGKKEPSTDHSQPRPPSN ENSRNOP00000050587/1-866 AAGYDGKAFSSPMIDLSAPVGGSYNLPSLPDIDCSSTILLDNIARKDTSVDPGQPRPPSN ENSMUSP00000031859/1-1051 AAGYDGKAFSSPMIDLSAPVGGSYNLPSLPDIDCSSTIMLDNIARKDTGVDHAQPRPPSN *******.*.*******:********************:**** :*:.. * .******* ENSP00000340507/1-1050 RTVQSPNSSVPSPGLAGPVTMTSVHPPIRSPSASSVGSRGSSGSSSKPAGADSTHKVPVV XP_004851301.1/1-1011 RTVQSPNSSVPSPGLAGPVTMTSVHPPIRSPSASSVGSRGSSGSSSKPTGADSTHKVPVV ENSCPOP00000010171/1-929 RTVQSPNSSVPSPGLAGPVTMTSVHPPIRSPSASSVGSRGSSGSSSKPTGADSTHKVPVV ENSRNOP00000050587/1-866 RTVQSPNSSVPSPGLAGPVTMTSVHPPIRSPSASSVGSRGSSGSSSKPAGADSTHKVPVV ENSMUSP00000031859/1-1051 RTVQSPNSSVPSPGLAGPVTMTSVHPPIRSPSASSVGSRGSSGSSSKPAGADSTHKVPVV ************************************************:*********** ENSP00000340507/1-1050 MLEPIRIKQENSGPPENYDFPVVIVKQESDEESRPQNANYPRSILTSLLLNSSQSSTSEE XP_004851301.1/1-1011 MLEPIRIKQENSGPPENYDFPVVIVKQESDEESRPQNTNYPRSILTSLLLNSSQSSASEE ENSCPOP00000010171/1-929 MLEPIRIKQENSGPPENYDFPVVIVKQESDEESRPQNTNYSRSILTSLLLNSSQRSASEE ENSRNOP00000050587/1-866 MLEPIRIKQENSGPPENYDFPVVIVKQESDEESRPQNTNYPRSILTSLLLNSSQSSASEE ENSMUSP00000031859/1-1051 MLEPIRIKQENSGPPENYDFPVVIVKQESDEESRPQNTNYPRSILTSLLLNSSQSSASEE *************************************:**.************* *:*** ENSP00000340507/1-1050 TVLRSDAPDSTGDQPGLHQDNSSNGKSEWLDPSQKSPLHVGETRKEDDPNEDWCAVCQNG XP_004851301.1/1-1011 TVVRSDAPDSTGDQPGLHQENPSNGKSEWPNASQKSPVHVGETRKEDDPNEDWCAVCQNG ENSCPOP00000010171/1-929 PVVRSDAPDSTGDQPGLHQENSSSGKSEWLDTSQKSPLHVGDTRKEDDPNEDWCAVCQNG ENSRNOP00000050587/1-866 TVLRSDAPDSTGDQPALHHENSPNGKSEWPDASQKSPVHVGETRKEDDPNED-------- ENSMUSP00000031859/1-1051 TVLRSDAPDSTGDQPGLHQENSSNGKSEWSDASQKSPVHVGETRKEDDPNEDWCAVCQNG .*:************.**::*...***** :.*****:***:********** ENSP00000340507/1-1050 GELLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFCRDLSKPEVEYDCDAPSHNSEKKKTE XP_004851301.1/1-1011 GELLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFCRDLSKPEVEYDCDAPTHNLEKKKTE ENSCPOP00000010171/1-929 GELLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFCRDLSKPEVEYDCDAPSHNLDKKKTE ENSRNOP00000050587/1-866 --------------------------CGEWICTFCRDLSKPEVEYDCDAPSHNSDKRKSE ENSMUSP00000031859/1-1051 GELLCCEKCPKVFHLTCHVPTLTNFPSGEWICTFCRDLSKPEVDYDCDVPSHHSEKRKSE .****************:****.*:*: :*:*:* ENSP00000340507/1-1050 GLVKLTPIDKRKCERLLLFLYCHEMSLAFQDPVPLTVPDYYKIIKNPMDLSTIKKRLQED XP_004851301.1/1-1011 GLVKLTPIDKRKCERLLLFLYCHEMSLAFQDPVPLIVPDYYKIIKNPMDLSTIKKRLQED ENSCPOP00000010171/1-929 ALVKLAPIDKRKCERLLLFLYCHEMSLAFQDPVPLTVPDYYKIIKNPMDLSTIKKRLQED ENSRNOP00000050587/1-866 GLTKLTPIDKRKCERLLLFLYCHEMSLAFQDPVPLT------------------------ ENSMUSP00000031859/1-1051 GLTKLTPIDKRKCERLLLFLYCHEMSLAFQDPVPLTVPDYYKIIKNPMDLSTIKKRLQED .*.**:***************************** ENSP00000340507/1-1050 YSMYSKPEDFVADFRLIFQNCAEFNEPDSEVANAGIKLENYFEELLKNLYPEKRFPKPEF XP_004851301.1/1-1011 SSLYTKPEDFVADFRLIFQNCAEFNEPDSEVANAGIKLESYFEELLKNLYPEKRFPKVEF ENSCPOP00000010171/1-929 SSLYTKPEDFVADFRLIFQNCAEFNEPDSEVANAGIKLESYFEELLKNLYPEKRFPKVEF ENSRNOP00000050587/1-866 --------------------------PDSEVANAGIKLESYFEELLKNLYPEKRFPKLEF ENSMUSP00000031859/1-1051 YCMYTKPEDFVADFRLIFQNCAEFNEPDSEVANAGIKLESYFEELLKNLYPEKRFPKVEF *************.***************** ** ENSP00000340507/1-1050 RNESEDNKFSDDSDDDFVQPRKKRLKSIEERQLLK------------------------- XP_004851301.1/1-1011 RNESEDNKFSDDSDDDFVQPRKKRLKSIEERQLLK------------------------- ENSCPOP00000010171/1-929 RNESEDNKCSDDSDDDFVQPRKKRLKSIEERQLLK------------------------- ENSRNOP00000050587/1-866 RHDVEDCKFSDDSDDDFVQPRKKRLKSMEDRQLLKTSTNIDLKSLGICETIPISSYLKEK ENSMUSP00000031859/1-1051 RHEAEDCKFSDDSDDDFVQPRKKRLKSTEDRQLLK------------------------- *:: ** * ****************** *:***** ENSP00000340507/1-1050 ------------------------------------------------------------ XP_004851301.1/1-1011 ------------------------------------------------------------ ENSCPOP00000010171/1-929 ------------------------------------------------------------ ENSRNOP00000050587/1-866 ERLRQPTAAHSQPRRHEVWRRKQSGVRTIKRGGPADERLVIAIAEDNIHFGQGLGGTEME ENSMUSP00000031859/1-1051 ------------------------------------------------------------ ENSP00000340507/1-1050 ------------------------------------------------------------ XP_004851301.1/1-1011 ------------------------------------------------------------ ENSCPOP00000010171/1-929 ------------------------------------------------------------ ENSRNOP00000050587/1-866 STWKPPPRGLILTSNDSQQAAKREEQSLVLPSGKAQTHNHQQQGNIPSGATVALTSADAD ENSMUSP00000031859/1-1051 ------------------------------------------------------------ ENSP00000340507/1-1050 ------------------------------------------------------------ XP_004851301.1/1-1011 ------------------------------------------------------------ ENSCPOP00000010171/1-929 ------------------------------------------------------------ ENSRNOP00000050587/1-866 ACVVIKDGVLNGKDAVSSAFMIYIEFAVIMLLNKKELTCGHETIILIRNIYLSSTWPRLL ENSMUSP00000031859/1-1051 ------------------------------------------------------------ ENSP00000340507/1-1050 ------------------------------------------------------------ XP_004851301.1/1-1011 ------------------------------------------------------------ ENSCPOP00000010171/1-929 ------------------------------------------------------------ ENSRNOP00000050587/1-866 SLLYDVSQMISHPCICHSDKFEEHPDFIRKGRDLVFERLDFSRLNKRGEIHIKLSGIIST ENSMUSP00000031859/1-1051 ------------------------------------------------------------ ENSP00000340507/1-1050 ------------------------------------------------------------ XP_004851301.1/1-1011 ------------------------------------------------------------ ENSCPOP00000010171/1-929 ------------------------------------------------------------ ENSRNOP00000050587/1-866 GRFKKLVKWLSAVRDAQAESSPGTSHASAPLPNAHLSSVNVDGVEVRRHQGPQHEEEANE ENSMUSP00000031859/1-1051 ------------------------------------------------------------ ENSP00000340507/1-1050 ---------------------------------------------------- XP_004851301.1/1-1011 ---------------------------------------------------- ENSCPOP00000010171/1-929 ---------------------------------------------------- ENSRNOP00000050587/1-866 AGTEEEAEEVIGTDTEDLPGWPHKALSLGRLLFLNRPNCGILSQFPHNPFTK ENSMUSP00000031859/1-1051 ----------------------------------------------------