CLUSTAL W(1.81) multiple sequence alignment ENSMUSP00000115127/1-449 ------------------------------------------------------------ ENSRNOP00000028936/1-815 ------------------------------------------------------------ ENSP00000283141/1-812 ------------------------------------------------------------ ENSCPOP00000010119/1-818 ------------------------------------------------------------ XP_004847925.1/1-968 MALVILQVKFYTTFGFEGAFCLHLKKTLVPIFVSCPYKRSLIRENVAMSTVRARPAGPAR ENSMUSP00000115127/1-449 ------------------------------------------------------------ ENSRNOP00000028936/1-815 ------------------------------------------------------------ ENSP00000283141/1-812 ------------------------------------------------------------ ENSCPOP00000010119/1-818 ------------------------------------------------------------ XP_004847925.1/1-968 DADVGRAFLDLKHRVSGTGSFNWTSRRRFKALSQLRPGLSPRLAGVSGSGRSAAPRPGMR ENSMUSP00000115127/1-449 -----------------------------------------------MSTLQSLIIDGFH ENSRNOP00000028936/1-815 ---------------------CTQKHEYPLRSIMKDAGTGQAQG---AFWLQSLVTDAFH ENSP00000283141/1-812 ---------------------MQAKNKDALQP-IKEDRTGKAQDD--AFWLQSLITDAFH ENSCPOP00000010119/1-818 ---------------------QQLNSENSLKP-TETSVMGKSNLQPSLLQLQSLITGAFH XP_004847925.1/1-968 AVSDPGLREGTEGSGSQGPGLGRENNEDVLQSVKEDDGLRKAQD---AFWLQSLITDAFH ****: ..** ENSMUSP00000115127/1-449 GNGFHMIEEYLQQKESHVPQKYNHLLLHHLDRLIKEELDKNEFQNCSLLLKCIQRFFRDD ENSRNOP00000028936/1-815 GKGFHTIEEYLQQRESQGPQKYTHLLLHHLDRLINEELDKNEFQNCSLLLKCIQRFFKED ENSP00000283141/1-812 DKGFQKIKEYFQQKESHFPQKYNRLLLYRLDRSINKELDKNEFQSVSLLLKCIQRFLVDG ENSCPOP00000010119/1-818 GKRFQEIQEYLQQKESQFPQKYDHLLLHHLDRSVNQELDKNEFQHVSLLLKCIQRFFKDD XP_004847925.1/1-968 GKGFQEIQAYLQQKESHLPQKYDHLLLHHLDGSVNKELDKNEFRHVSLLLKCVQRFFKDD .: *: *: *:**:**: **** :***::** :::*******: ******:***: :. ENSMUSP00000115127/1-449 PDHEEPLLIQQGLIPKMVSWFEIITGLLITKVLASEALLTNALEDFLDTALIISRHSRKA ENSRNOP00000028936/1-815 SDQEESLLIQQGLIPKMVSWFETMTGFLMTEVLASEALLTNAVEDFLDTALIVSRHSRTG ENSP00000283141/1-812 LKEDEPLLIRQGLIPKLVSWFERTTGILTSEGLASDTSLICVIEDFFDTALIISRSSSEG ENSCPOP00000010119/1-818 LGKEEPLLIQQGLIPKMASWFERTTGFLSTDTLASDTALADLLEDFLDSALIISSSSTKG XP_004847925.1/1-968 LRKDETLLIQQGLIPKMASWFERTTGFLGTEALASSTVLKPVIEDFFDTALIISRSSPKG .:*.***:******:.**** **:* :. ***.: * :***:*:***:* * . ENSMUSP00000115127/1-449 TVQMLDSFILRLGFLVAEDSVKPSIQQETLATLNCILNAAPQEERRKLSSAEGACCLMKE ENSRNOP00000028936/1-815 TIQMLDSFILRLGFLVTEGSVKPYIQQEALKTVNCILNAAPREERRKLSSTEGARCLMKE ENSP00000283141/1-812 KIQMLDSFLLSLGFLVTEKTVNHLLQQEGLKTFNCILHAVPREERKKFPLSEGMCHLMKD ENSCPOP00000010119/1-818 KIQMLDSFIFSLGLLVTEKTVNLLIQQEALRTLNSILQGIPRTEKRRLPLAEGMSNLMKD XP_004847925.1/1-968 KIQMLDSFILILGFLVTEKTVNHLIQQEALRTLNSILQGIPREERRRLPSAEGACHLMKD .:******:: **:**:* :*: :*** * *.*.**:. *: *::::. :** ***: ENSMUSP00000115127/1-449 LARTILTVGDYSQQVALSEALCRMSVGRQRNDLAMQWFENTALAEAFKKIKNREFETDCR ENSRNOP00000028936/1-815 LARTILTVGDYSQQVALSEALCRMAVGSWRNELATQWFEDTVLAEAFKEVKNWEFETDCR ENSP00000283141/1-812 LARTLLTVGDYDQQVAISEALCRLTIKKSRDELVHKWFDDEVIAEAFKEIKDREFETDSR ENSCPOP00000010119/1-818 FARTILTVGDYDQQIALSEALCRMTTRASRGTLVHQWFDDDVLAQGFKQIRDREFETDSR XP_004847925.1/1-968 LARTILTVGDYDQQVALSEALCRMTSRTSRNDLVHQWFDDDVLAEGFKKIKDREFETDGR :***:******.**:*:******:: *. *. :**:: .:*:.**:::: ***** * ENSMUSP00000115127/1-449 QFLNFLNNRLGNQRRVYSFPCLAAFADGQEMRKPADEKLEEFWIDFNLGSQSVTFYIDNA ENSRNOP00000028936/1-815 QFLNFLNNRLGDQRRVYSFPCLAAFADAQEMRKPADEKLEEFWIDFNLGSQSVTFYIDNA ENSP00000283141/1-812 RFLNHLNNRLGDQRRVYSFPCIAAFADEHEMRKPADEKLEKFWIDFNLGSQSVTFYIDNA ENSCPOP00000010119/1-818 RFLNHLNDRLGDQRRVYSFPCVAAFAAGHEMRKPANENLEHFWIDFNLGSQSVTFYIDNA XP_004847925.1/1-968 RFLNHLNDRLGDQRRVYSFACVAAFADGHEMRKPADEKLEKFWIDFNLGSQSVTFYIDNA :***.**:***:*******.*:**** :******:*:**.******************* ENSMUSP00000115127/1-449 ESALWEPVKLLKEAMVKFIIIENDRIKMFIVYLKQPIVISKREAKKIEIHFDRQLGILQA ENSRNOP00000028936/1-815 ESALWEPVQLLKEAVTKFFIIERQLLLLLLLCLERHGMVPYKRILISLLSFDVAFSQAE- ENSP00000283141/1-812 ENTLWDSVTLPKEAVMNFSITETEKIKIFIIYLKKPMIISYKEVMKIEIHFDLQFNISQV ENSCPOP00000010119/1-818 ESTLWEPVRLAKESMHNFSITENEKVKILIIYLKAPVVISKKEVMDVAIHFNLQDHVSQA XP_004847925.1/1-968 ESALWEPIRVAKEAVVNFGITENEKAKIFIIYLKEPIVISKKEVMKIEIHFDLQVHISQA *.:**:.: : **:: :* * * : :::: *: ::. :. : *: : ENSMUSP00000115127/1-449 SIQALGEDKQAPSFQTSVLVKLFSGLEKEDGEIPGRCEREAEDAEESTLLPELVDAEADR ENSRNOP00000028936/1-815 DLRILGSVKKAHSFQASVLIKVSSGLEKEDGEIPSSLEGETEDKEESTVLPEFVDAEVDQ ENSP00000283141/1-812 SIQALGEDKQMLPDQTKISSELFSKSDKEDRESPSGLERETEQAEESTNMVEFMSAEDDR ENSCPOP00000010119/1-818 AARALGEEKQVLPGQMKISLESFSKFEK-DSEIPSNLERQTEQAEESTELAESVSAEVDR XP_004847925.1/1-968 SVQALGEDKQVLPDQMKMSSEHFKKSEKEDSEIPSSLERQTEQAEESTEAAESMSAGGDR : **. *: . * .: : . :* * * *. * ::*: **** * :.* *: ENSMUSP00000115127/1-449 CLITRCFNVQTVPGV--------------------------------------------- ENSRNOP00000028936/1-815 CLITRRFNVQSVPTV------------------SKGSQEQTKSEDCSPE--------NSK ENSP00000283141/1-812 CLITLHLNDQSEPPV------------------IGEPASDSHLQPVPPF---------GV ENSCPOP00000010119/1-818 CVITVLSGPQPGPPV------------------YGYLSIKSGFEPKPVF--------ALL XP_004847925.1/1-968 CVITLLSDSQAGPPVKVTSKHEHSSIVQDPSVQIQAPKLDDKSREGSAFEDDTKQERGIS *:** . *. * * ENSMUSP00000115127/1-449 ------------------------------------------------------------ ENSRNOP00000028936/1-815 PDEPEQEKFNDRKHYILESNEGSSSNTSERSWTQNHKRKSLRTYSQRRKTRV-SSLRILP ENSP00000283141/1-812 PDFPQQPKSHYRKHLFSESNQDSS--TSELSWTSNQKKKSLKSYSSRKKTRTRSNLRILP ENSCPOP00000010119/1-818 FFSQVGEKFSYRRHLFSERERDSSSSASELSWFANQKKKSLRPYASRRKPRVRSSTRILP XP_004847925.1/1-968 DTKKKRTPFDYRKHLFSEEEHGSSSSTNEQSWTSNQKRKSLKPYSSRKKTRVRSRLKILP ENSMUSP00000115127/1-449 ------------------------------------------------------------ ENSRNOP00000028936/1-815 LSPIRSGRVPEKDEAEL-TPLWKGIPRRNNSTPLNISETKLRESSVLLTPEASTQKIEFQ ENSP00000283141/1-812 VFPPSSGSGHEKDQAKLLSPSEKEIPEQNNTTSPKTSEQKFQDSFAFLTAEDSAQKTELQ ENSCPOP00000010119/1-818 LFPPIRGSEHEKGQAKLPTPGWQDSSRLKNATPSEMSEKILQGSSALLSPEKSVQKTELQ XP_004847925.1/1-968 LFPHSSASEHEKSQAKLLTPVWKDSSRQNNATPSEMSGRKLQGSSGFLSLKDSAQKTELQ ENSMUSP00000115127/1-449 ------------------------------------------------------------ ENSRNOP00000028936/1-815 SPHSSSSLSSLERPEVEKNEPQIVNCEPFMGNRSSKHKLESSEHRETPDGSAVALKQSRL ENSP00000283141/1-812 DPHSLSELSSLKHSE-DEEKPKIVNQESLTESTSLKHKLRNLEDKDIPEGSFAKSQQSRL ENSCPOP00000010119/1-818 SPHSASDLFSFEDSEVEEDLSQIITQESLMENTGFKHKLENLEDKDAPEWSFAKAKQSRL XP_004847925.1/1-968 SPHPLSDLPALEDSEVEENVSQIINQESLMENTGFKHKLANLEDKDSPEGSFAKPKQSRL ENSMUSP00000115127/1-449 ------------------------------------------------------------ ENSRNOP00000028936/1-815 E--DAPGSPIVAEHRPYMPSLSDISTPSQEDVPENTNSSALKMAFENFTRDLKRKFELRL ENSP00000283141/1-812 EEEVAPGSPFSITEERELPE--GISTSSLEVVPENLNGSAILPTFENFTKKRKRKYELRY ENSCPOP00000010119/1-818 EAGDVPGSSGLAVKDKHDPFL-DISTPYLGDVPENLEVSAIVAALENCTGALKRKYELSY XP_004847925.1/1-968 EDGDVPGPPSLA-----------------DIVPENLDGSAVITALENFTGELKRRYELGY ENSMUSP00000115127/1-449 ------------------------------------------------------------ ENSRNOP00000028936/1-815 KQREIPLSSEKAKEVPACLIRLWNQIHTCRQDKLEGFHSSVLQELGSLEKDLQTLECLEK ENSP00000283141/1-812 RKR--PFNSENAKKAPDCLIKLLNQMQLFRLNKLERFQNLVLQELSSLKQDIQALEHLEK ENSCPOP00000010119/1-818 RES--PVHSNVAKKAPDCLLKLLSQIHLHRLNKLEDFRKFVLQKLSSLEKDILALEHLEK XP_004847925.1/1-968 RKS--PVYSKTAKKAPDCLLKLLNQIHLHRLNKLENFHNFVLQQLSNLEKDIQALKHLEK ENSMUSP00000115127/1-449 -----------------------------S ENSRNOP00000028936/1-815 DALEFWERQSADLQSFCDQQVWRYYTTILL ENSP00000283141/1-812 EVLEFWGKQSADLQSFCDLQVLRFNSTQTS ENSCPOP00000010119/1-818 DVLEFWEKQSDDLRSFCDMQVLRYFFKDTS XP_004847925.1/1-968 DVLEFWEKQSDDLKSFCDLQVLRLNPIQPS