CLUSTAL W(1.81) multiple sequence alignment ENSCPOP00000010099/1-773 ------------------------------------------------------------ XP_004851166.1/1-1282 MKLATGLWGWLSLLVAAGTVRPGASQSVCAGTENKLSSLSDLEQQYRALRKYYENCEVVM ENSP00000342235/1-1308 MKPATGLWVWVSLLVAAGTVQPSDSQSVCAGTENKLSSLSDLEQQYRALRKYYENCEVVM ENSMUSP00000112713/1-1308 MKLATGLWVWGSLLMAAGTVQPSASQSVCAGTENKLSSLSDLEQQYRALRKYYENCEVVM ENSRNOP00000019283/1-1281 --------------------------SVCAGTENKLSSLSDLEQQYRALRKYYENCEVVM ENSCPOP00000010099/1-773 ------------------------------------------------------------ XP_004851166.1/1-1282 GNLEITSIEHNRDLSFLRSIREVTGYVLVALNQFRYLPLENLRIIRGTKLYEDRYALAIF ENSP00000342235/1-1308 GNLEITSIEHNRDLSFLRSVREVTGYVLVALNQFRYLPLENLRIIRGTKLYEDRYALAIF ENSMUSP00000112713/1-1308 GNLEITSIEHNRDLSFLRSIREVTGYVLVALNQFRYLPLENLRIIRGTKLYEDRYALAIF ENSRNOP00000019283/1-1281 GNLEITSIEHNRDLSFLRSIREVTGYVLVALNQFRYLPLENLRIIRGTKLYEDRYALAIF ENSCPOP00000010099/1-773 ------------------------------------------------------------ XP_004851166.1/1-1282 LNYRKDGNFGLQELGLKNLTEILNGGVYVDQNKFLCYADTIHWQDIVRNPWPSNLTLVST ENSP00000342235/1-1308 LNYRKDGNFGLQELGLKNLTEILNGGVYVDQNKFLCYADTIHWQDIVRNPWPSNLTLVST ENSMUSP00000112713/1-1308 LNYRKDGNFGLQELGLKNLTEILNGGVYVDQNKFLCYADTIHWQDIVRNPWPSNMTLVST ENSRNOP00000019283/1-1281 LNYRKDGNFGLQELGLKNLTEILNGGVYVDQNKFLCYADTIHWQDIVRNPWPSNMTLVST ENSCPOP00000010099/1-773 ------------------------------------------------CC---------- XP_004851166.1/1-1282 NGSSGCGRCHKSCTGRCWGPTENHCQTLTRTVCAEQCDGRCYGPYVSDCCHRECAGGCSG ENSP00000342235/1-1308 NGSSGCGRCHKSCTGRCWGPTENHCQTLTRTVCAEQCDGRCYGPYVSDCCHRECAGGCSG ENSMUSP00000112713/1-1308 NGSSGCGRCHKSCTGRCWGPTENHCQTLTRTVCAEQCDGRCYGPYVSDCCHRECAGGCSG ENSRNOP00000019283/1-1281 IGSSGCGRCHKSCTGRCWGPTENHCQTLTRTVCAEQCDGRCYGPYVSDCCHRECAGGCSG ** ENSCPOP00000010099/1-773 ------------------------------------------------------------ XP_004851166.1/1-1282 PKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQLEHNFNAKYTYGAFCVKKCPHNFVVD ENSP00000342235/1-1308 PKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQLEHNFNAKYTYGAFCVKKCPHNFVVD ENSMUSP00000112713/1-1308 PKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQLEHNFNAKYTYGAFCVKKCPHNFVVD ENSRNOP00000019283/1-1281 PKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQLEHNFNAKYTYGAFCVKKCPHNFVVD ENSCPOP00000010099/1-773 ------------------------------------------------------------ XP_004851166.1/1-1282 SSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLMSAQTVDSSNIDKFINCT ENSP00000342235/1-1308 SSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLMSAQTVDSSNIDKFINCT ENSMUSP00000112713/1-1308 SSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLMSAQTVDSSNIDKFINCT ENSRNOP00000019283/1-1281 SSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLMSAQTVD-SNIDKFINCT ENSCPOP00000010099/1-773 ------------------------------------------------------------ XP_004851166.1/1-1282 KINGNLIFLVTGIHGDPYNAIEAIDPEKLNVFRTVREITGFLNIQSWPPNMTDFSVFSNL ENSP00000342235/1-1308 KINGNLIFLVTGIHGDPYNAIEAIDPEKLNVFRTVREITGFLNIQSWPPNMTDFSVFSNL ENSMUSP00000112713/1-1308 KINGNLIFLVTGIHGDPYNAIDAIDPEKLNVFRTVREITGFLNIQSWPPNMTDFSVFSNL ENSRNOP00000019283/1-1281 KINGNLIFLVTGIHGDPYNAIDAIDPEKLNVFRTVREITGFLNIQSWPPNMTDFSVFSNL ENSCPOP00000010099/1-773 ----------------------------------------------CFH----------- XP_004851166.1/1-1282 VTIGGRVLYSGLSLLILKQQGITSLQFQSLKEISAGNIYITDNSNLCYYHTINWTTLFST ENSP00000342235/1-1308 VTIGGRVLYSGLSLLILKQQGITSLQFQSLKEISAGNIYITDNSNLCYYHTINWTTLFST ENSMUSP00000112713/1-1308 VTIGGRVLYSGLSLLILKQQGITSLQFQSLKEISAGNIYITDNSNLCYYHTINWTTLFST ENSRNOP00000019283/1-1281 VTIGGRVLYSGLSLLILKQQGITSLQFQSLKEISAGNIYITDNSNLCYYHTINWTTLFST *:: ENSCPOP00000010099/1-773 ------------------------------------------------------------ XP_004851166.1/1-1282 INQRIVIRDNRKAENCTAEGMVCNQLCSSNGCWGPGPDQCLSCRRFSRGRICIESCNLYD ENSP00000342235/1-1308 INQRIVIRDNRKAENCTAEGMVCNHLCSSDGCWGPGPDQCLSCRRFSRGRICIESCNLYD ENSMUSP00000112713/1-1308 INQRIVIRDNRRAENCTAEGMVCNHLCSNDGCWGPGPDQCLSCRRFSRGKICIESCNLYD ENSRNOP00000019283/1-1281 VNQRIVIRDNRRAENCTAEGMVCNHLCSNDGCWGPGPDQCLSCRRFSRGKICIESCNLYD ENSCPOP00000010099/1-773 SEFREFENGSVCVECDPQCEKVEEGLLTCHGPGPDNCTKCSHFKDGPNCVEKCPDGLQGA XP_004851166.1/1-1282 GELREFENGSVCVECDSQCEKMEEGLLTCHGPGPDNCTKCSHFKDGPNCVEKCPDGLQGA ENSP00000342235/1-1308 GEFREFENGSICVECDPQCEKMEDGLLTCHGPGPDNCTKCSHFKDGPNCVEKCPDGLQGA ENSMUSP00000112713/1-1308 GEFREFENGSICVECDSQCEKMEDGLLTCHGPGPDNCTKCSHFKDGPNCVEKCPDGLQGA ENSRNOP00000019283/1-1281 GEFREFENGSICVECDSQCEKMEDGLLTCHGPGPDNCTKCSHFKDGPNCVEKCPDGLQGA .*:*******:*****.****:*:************************************ ENSCPOP00000010099/1-773 NSFIFKYADQDRECHPCHPNCTQGCNGPTIHDCIYYPWTGHSTLPQHARTPLIAAGVIGG XP_004851166.1/1-1282 NSFIFKYADQDRECHPCHPNCTQGCIGSTIEDCI----------GLMDRTPLIAAGVIGG ENSP00000342235/1-1308 NSFIFKYADPDRECHPCHPNCTQGCNGPTSHDCIYYPWTGHSTLPQHARTPLIAAGVIGG ENSMUSP00000112713/1-1308 NSFIFKYADQDRECHPCHPNCTQGCNGPTSHDCIYYPWTGHSTLPQHARTPLIAAGVIGG ENSRNOP00000019283/1-1281 NSFIFKYADQDRECHPCHPNCTQGCNGPTSHDCIYYPWTGHSTLPQHARTPLIAAGVIGG ********* *************** *.* .*** ************ ENSCPOP00000010099/1-773 LFILVIVGLTFAVYVRRKSIKKKRALRRFLETELVEPLTPSGTAPNQAQLRILKETELKR XP_004851166.1/1-1282 LFILVIVGLTFAVYVRRKSIKKKRALRRFLETELVEPLTPSGTAPNQAQLRILKETELKR ENSP00000342235/1-1308 LFILVIVGLTFAVYVRRKSIKKKRALRRFLETELVEPLTPSGTAPNQAQLRILKETELKR ENSMUSP00000112713/1-1308 LFILVIMALTFAVYVRRKSIKKKRALRRFLETELVEPLTPSGTAPNQAQLRILKETELKR ENSRNOP00000019283/1-1281 LFILVIMALTFAVYVRRKSIKKKRALRRFLETELVEPLTPSGTAPNQAQLRILKETELKR ******:.**************************************************** ENSCPOP00000010099/1-773 IKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHL XP_004851166.1/1-1282 IKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHL ENSP00000342235/1-1308 VKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHL ENSMUSP00000112713/1-1308 VKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHL ENSRNOP00000019283/1-1281 VKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASVDHPHL :*****************************************************:***** ENSCPOP00000010099/1-773 VRLLGVCLSPTIQLVTQLMPHGCLLDYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLV XP_004851166.1/1-1282 VRLLGVCLSPTIQLVTQLMPHGCLLDYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLV ENSP00000342235/1-1308 VRLLGVCLSPTIQLVTQLMPHGCLLEYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLV ENSMUSP00000112713/1-1308 VRLLGVCLSPTIQLVTQLMPHGCLLDYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLV ENSRNOP00000019283/1-1281 VRLLGVCLSPTIQLVTQLMPHGCLLEYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLV *************************:********************************** ENSCPOP00000010099/1-773 HRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQ XP_004851166.1/1-1282 HRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQ ENSP00000342235/1-1308 HRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQ ENSMUSP00000112713/1-1308 HRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQ ENSRNOP00000019283/1-1281 HRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQ ************************************************************ ENSCPOP00000010099/1-773 SDVWSCGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMID XP_004851166.1/1-1282 SDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMID ENSP00000342235/1-1308 SDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMID ENSMUSP00000112713/1-1308 SDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMID ENSRNOP00000019283/1-1281 SDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMID ***** ****************************************************** ENSCPOP00000010099/1-773 ADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMKLPSPNDSKFFQNLLDEEDLEDMMDAE XP_004851166.1/1-1282 ADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMKLPSPNDSKFFQNLLDEEDLEDMMDAE ENSP00000342235/1-1308 ADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMKLPSPNDSKFFQNLLDEEDLEDMMDAE ENSMUSP00000112713/1-1308 ADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMKLPSPNDSKFFQNLLDEEDLEDMMDAE ENSRNOP00000019283/1-1281 ADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMKLPSPNDSKFFQNLLDEEDLEDMMDAE ************************************************************ ENSCPOP00000010099/1-773 EYLVPQAFNIPPPIYTSRARIDSNRSEIGHSPPPAYTPMSGNQFVYRDGGFAAEQGMPVP XP_004851166.1/1-1282 EYLVPQAFNIPPPIYTSRARIDSNR----------------NQFVYRDGGFAPEQGMPVP ENSP00000342235/1-1308 EYLVPQAFNIPPPIYTSRARIDSNRSEIGHSPPPAYTPMSGNQFVYRDGGFAAEQGVSVP ENSMUSP00000112713/1-1308 EYLVPQAFNIPPPIYTSRTRIDSNRSEIGHSPPPAYTPMSGNQFVYQDGGFATQQGMPMP ENSRNOP00000019283/1-1281 EYLVPQAFNIPPPIYTSRTRIDSNRSEIGHSPPPAYTPMSGNQFVYQDGGFATQQGMPMP ******************:****** *****:*****.:**:.:* ENSCPOP00000010099/1-773 YRATTSTIPEAPAAQGATAEIFDDSCCNGTLRKPVAPHSQEDSSTQRYSADPTVFASERS XP_004851166.1/1-1282 YRATTSTIPEAPVAQGAAAEIFDDSCCNGTLRKPVVPHAQEDSSTQRYSADPTLFAPERS ENSP00000342235/1-1308 YRAPTSTIPEAPVAQGATAEIFDDSCCNGTLRKPVAPHVQEDSSTQRYSADPTVFAPERS ENSMUSP00000112713/1-1308 YRATTSTIPEAPVAQGATAEMFDDSCCNGTLRKPVAPHVQEDSSTQRYSADPTVFAPERN ENSRNOP00000019283/1-1281 YRATTSTIPEAPVAQGATAEMFDDSCCNGTLRKPVVPHVQEDSSTQRYSADPTVFAPERN ***.********.****:**:**************.** **************:**.**. ENSCPOP00000010099/1-773 PRGELDEEGYMTPMRDKPKQEYLNPVEENPFVSRRKNGNPQALDNPEYHKAANGPPKTED XP_004851166.1/1-1282 PRGELDEEGYMTPMRDKPKQEYLNPVEENPFVSRRKNGDLQALDNPEYHNASNGPPKAED ENSP00000342235/1-1308 PRGELDEEGYMTPMRDKPKQEYLNPVEENPFVSRRKNGDLQALDNPEYHNASNGPPKAED ENSMUSP00000112713/1-1308 PRGELDEEGYMTPMHDKPKQEYLNPVEENPFVSRRKNGDLQALDNPEYHSASSGPPKAED ENSRNOP00000019283/1-1281 PRAELDEEGYMTPMHDKPKQEYLNPVEENPFVSRRKNGDLQALDNPEYHSASSGPPKAED **.***********:***********************: *********.*:.****:** ENSCPOP00000010099/1-773 EYVNEPLYLNTFANALGKAEYLKNSVLSVPEKAKKAFDNPDYWNHSLPPRSTLQHPDYLQ XP_004851166.1/1-1282 EYVNEPLYLNTFANALGNAEYLKNSVLSVPEKAKKAFDNPDYWNHSLPPRSTLQHPDYLQ ENSP00000342235/1-1308 EYVNEPLYLNTFANTLGKAEYLKNNILSMPEKAKKAFDNPDYWNHSLPPRSTLQHPDYLQ ENSMUSP00000112713/1-1308 EYVNEPLYLNTFANALGSAEYMKNSVLSVPEKAKKAFDNPDYWNHSLPPRSTLQHPDYLQ ENSRNOP00000019283/1-1281 EYVNEPLYLNTFTNALGNAEYMKNSLLSVPEKAKKAFDNPDYWNHSLPPRSTLQHPDYLQ ************:*:**.***:**.:**:******************************* ENSCPOP00000010099/1-773 EYSTKYFYKQNGRIRPIVAENPEYLSEFSLKPGTVLPPPPYRHRNTVV XP_004851166.1/1-1282 EYSTKYFYKQNGRIRPIVAENPEYLSEFSLKPGTVLPPPPYRHRNTVV ENSP00000342235/1-1308 EYSTKYFYKQNGRIRPIVAENPEYLSEFSLKPGTVLPPPPYRHRNTVV ENSMUSP00000112713/1-1308 EYSTKYFYKQNGRIRPIVAENPEYLSEFSLKPGTMLPPPPYRHRNTVV ENSRNOP00000019283/1-1281 EYSTKYFYKQNGRIRPIVAENPEYLSEFSLKPGTMLPPPPYRHRNTVV **********************************:*************