CLUSTAL W(1.81) multiple sequence alignment ENSMUSP00000002305/1-940 MAGAAAAVAAGAAAGAAAAAGSVSAPGRASAPPPPPPVYCVCRQPYDVNRFMIECDVCKD ENSRNOP00000066727/1-843 ------------------------------------------------------------ ENSP00000380692/1-941 MAGAAAAVAAGAAAGAAAAAVSVAAPGRASAPPPPPPVYCVCRQPYDVNRFMIECDICKD ENSCPOP00000010087/1-895 ---------------------------------------------------LIDCQTVHV XP_004851336.1/1-942 MAGAAAAVAAGAAAGAAAAAVSVAAPGRASAPPPPPPVYCVCRQPYDVNRFMIECDICKD ENSMUSP00000002305/1-940 ----WFHGSCVGVEEHHAVDIDLYHCPDCAALHGSSLMKKRRNWHRHDYTEVDDGSKPVQ ENSRNOP00000066727/1-843 -------------------------------------VKKRRNWHRHDYTEADDGSKPVQ ENSP00000380692/1-941 ----WFHGSCVGVEEHHAVDIDLYHCPNCAVLHGSSLMKKRRNWHRHDYTEIDDGSKPVQ ENSCPOP00000010087/1-895 LTFIFLYFSCVGVEEHHAVDIDLYHCPNCALLHGSSLMKKRRNWHRHDYTEVDDGSKPVQ XP_004851336.1/1-942 ----WFHGSCVGVEEHHAVDIDLYHCPNCALLHGSSLMKKRRNWHRHDYTEIDDGSKPVQ :************* ******** ENSMUSP00000002305/1-940 AGTRAFVKELRSRVFPSADEIIVKMHGSQLTQRYLEKHGFDVPIMVPKLDDLGLRLPSPA ENSRNOP00000066727/1-843 AGTRAFVKELRSRVFPSADEVIVKMHGSQLTQRYLEKHGFDVPIMVPKLDDLGLRLPSPA ENSP00000380692/1-941 AGTRTFIKELRSRVFPSADEIIIKMHGSQLTQRYLEKHGFDVPIMVPKLDDLGLRLPSPT ENSCPOP00000010087/1-895 AGTRTFVKELRARIFPSADEIIVKMHGSQLTQRYLEKHGFDAPIMVPKLDDLGLRLPSPA XP_004851336.1/1-942 AGTRTFVKELRARVFPSADEIIVKMHGSQLTQRYLEKHGFDAPIMVPKLDDLGLRLPPPA ****:*:****:*:******:*:******************.***************.*: ENSMUSP00000002305/1-940 FSVMDVERYVGGDKVIDVIDVARQADSKMTLHNYVKYFMNPDRPKVLNVISLEFSDTKMS ENSRNOP00000066727/1-843 FSVMDVERYVGGDKVIDVIDVARQADSKMTLHNYVKYFMNPNRPKVLNVISLEFSDTKMS ENSP00000380692/1-941 FSVMDVERYVGGDKVIDVIDVARQADSKMTLHNYVKYFMNPNRPKVLNVISLEFSDTKMS ENSCPOP00000010087/1-895 FSVMDVERYVGGDKVIDVIDVARQADSKMTLHNYVKYFTNPDRPKVLNVISLEFSDTKMS XP_004851336.1/1-942 FSVLDVERYVGGDKVIDVIDVARQADSKMTLHNYVKYFMKPNRPKVLNVISLEFSDTKMS ***:********************************** :*:****************** ENSMUSP00000002305/1-940 ELVEVPDIARKLSWVENYWPDDSVFPKPFVQKYCLMGVQDSYTDFHIDFGGTSVWYHVLW ENSRNOP00000066727/1-843 ELVEVPDIARKLSWVENYWPDDSVFPKPFVQKYCLMGVQDSYTDFHIDFGGTSVWYHVLW ENSP00000380692/1-941 ELVEVPDIAKKLSWVENYWPDDSVFPKPFVQKYCLMGVQDSYTDFHIDFGGTSVWYHVLW ENSCPOP00000010087/1-895 ELVEVPDIARKLSWVENYWPDDSVFPKPFVQKYCLMGVQDSYTDFHIDFGGTSVWYHVLW XP_004851336.1/1-942 ELVEVPDIARKLSWVENYWPDDSVFPKPFVQKYCLMGVQDSYTDFHIDFGGTSVWYHVLW *********:************************************************** ENSMUSP00000002305/1-940 GEKIFYLIKPTNENLALYESWSSSVTQSEVFFGDKVDKCYKCVVKQGHTLFVPTGWIHAV ENSRNOP00000066727/1-843 GEKIFYLIKPTNENLALYESWSSSVTQSEVFFGDKVDKCYKCVVKQGHTLFVPTGWIHAV ENSP00000380692/1-941 GEKIFYLIKPTDENLARYESWSSSVTQSEVFFGDKVDKCYKCVVKQGHTLFVPTGWIHAV ENSCPOP00000010087/1-895 GEKIFYLIKPTNENLALYESWSSSVTQSEVFFGDKVDKCYKCVVKQGHTLFVPTGWIHAV XP_004851336.1/1-942 GEKIFYLIKPTNENLALYESWSSSVTQSEVFFGDKVDKCYKCVVKQGHTLFVPTGWIHAV ***********:**** ******************************************* ENSMUSP00000002305/1-940 LTSQDCMAFGGNFLHNLNIGMQLRCYEMEKRLKTPDLFKFPFFEAICWFVAKSLLETLKE ENSRNOP00000066727/1-843 LTSQDCMAFGGNFLHNLNIGMQLRCYEMEKRLKTPDLFKFPFFEAICWFVAKSLLETLKE ENSP00000380692/1-941 LTSQDCMAFGGNFLHNLNIGMQLRCYEMEKRLKTPDLFKFPFFEAICWFVAKNLLETLKE ENSCPOP00000010087/1-895 LTSQDCMAFGGNFLHNLNIGMQLRCYEMEKRLKTPDLFKFPFFEAICWFVAKNLLETLKE XP_004851336.1/1-942 LTSQDCMAFGGNFLHNLNIGMQLRCYEMEKRLKTPDLFKFPFFEAICWFVAKNLLETLKE ****************************************************.******* ENSMUSP00000002305/1-940 LKEDGFQPQSYLVQGVKALHTALKLWMKKELVSEHAFEIPDNVRPGHLIKELSKVIRAIE ENSRNOP00000066727/1-843 LKEDGFQPQTYLVQGVKALHTALKLWMKKELVSEHAFEIPDNVRPGHLIKELSKVIRAIE ENSP00000380692/1-941 LREDGFQPQTYLVQGVKALHTALKLWMKKELVSEHAFEIPDNVRPGHLIKELSKVIRAIE ENSCPOP00000010087/1-895 LREDGFQPQTYLVQGVKALHTALKLWMKKELVSEHAFEIPDNVRPGHLIKELSKVIRAIE XP_004851336.1/1-942 LREDGFQPQTYLVQGVKALHTALKLWMKKELVSEHAFEIPDNVRPGHLIKELSKVIRAIE *:*******:************************************************** ENSMUSP00000002305/1-940 EENGKPVKSQGIPSVCPVSRPSNEASPPYHSRRKMRKLRDHNVRTPSNLDILELHTREVL ENSRNOP00000066727/1-843 EENGKPVKSQGIPSVCPVSRPSNDASPPGHSRRKMRRLRDHNVRTPSNLDILELHTREVL ENSP00000380692/1-941 EENGKPVKSQGIPIVCPVSRSSNEATSPYHSRRKMRKLRDHNVRTPSNLDILELHTREVL ENSCPOP00000010087/1-895 EENSKPVKSQGIPTVCPVARSSNEATSPYHSRRKMRKLRDHNVRTPSNLDILELHTREVL XP_004851336.1/1-942 EENSKPVKSQGIPTVCPVSRSSIEATSSYHSRRKMRKLRDHSVRTPSNLDILELHTREVL ***.********* ****:*.* :*:.. *******:****.****************** ENSMUSP00000002305/1-940 KRLEMCPWEEDLLSSKLNGKFNKHLQPSSTVPEWRAKDNDLRLLLTNGRIIKDERQLFAD ENSRNOP00000066727/1-843 KRLEMCPWEEDILSSKLNGKFNKHLQPSSTVPEWRAKDNDLRLLLTNGRIIKDERQLFAD ENSP00000380692/1-941 KRLEMCPWEEDILSSKLNGKFNKHLQPSSTVPEWRAKDNDLRLLLTNGRIIKDERQPFAD ENSCPOP00000010087/1-895 KRLEMCPWEEDTLSSKLNGKFNKHLQPSSTVPEWRAKDNDLRLLLTNGRIIKDERQPFAD XP_004851336.1/1-942 KRLEMCPWEEDTLSSKLNGKFNKHLQPSSTVPEWRAKDNDLRLLLTNGRIIKDERQPFAD *********** ******************************************** *** ENSMUSP00000002305/1-940 RSLYTADSENEEDKKPTQNANMKTEQSSGREEAESQGSPKPLNRIFTSVRSELRSRPSEY ENSRNOP00000066727/1-843 RSLYTADSENEEDKKPTKKANVKTEQSSGREAAESDGSPKPLNRIFPSVKSELRSRPSEY ENSP00000380692/1-941 QSLYTADSENEEDKRRTKKAKMKIEESSGVEGVEHEESQKPLNGFFTRVKSELRSRSSGY ENSCPOP00000010087/1-895 QSLYTADSESEDDKRRTRKANMKTEASSEIEGTEREEPPKPLNRLFTSVKSELRSRSSEY XP_004851336.1/1-942 QSLYTADSENEEDKRRTKKANVKTEASSGTEGMESEEPQKPLNRLFTSVKSELRNRSSEY :********.*:**: *::*::* * ** * * : . **** :*. *:****.*.* * ENSMUSP00000002305/1-940 SDGSDSEDSGPDCTALKINFATEDSESSGDEKKHEITSHFKEESDIVRNLLQKSQKPSRQ ENSRNOP00000066727/1-843 SDVSDSEDSGPDCTAVKINFATEESESSGDEKKHEITSNFKEESDVVRNLLQKSQKPSRN ENSP00000380692/1-941 SDISESEDSGPECTALKSIFTTEESESSGDEKKQEITSNFKEESNVMRNFLQKSQKPSRS ENSCPOP00000010087/1-895 SDISDSEDSGPDCTALKINFTTEESESSGDEKKQEVTSNFKEESNAMKNFLQKSQKPSRS XP_004851336.1/1-942 SDISDSEDSGPDCTALKINFTTEESESSGDEKKQEVTSNFKEESNVMKNFFQKSQKPSRS ** *:******:***:* *:**:*********:*:**:*****: ::*::********. ENSMUSP00000002305/1-940 EIPVKRECPTSTSTEEEAIQGMLSMAGLHYSSCLQRQIQSTDCSGEKNSLQDPSSCHGSN ENSRNOP00000066727/1-843 EIPVKRECPTSTSTEEEAIQGMLSMAGLHYSTCL----QSTDCSGEKNSLQDPSSCHSSN ENSP00000380692/1-941 EIPIKRECPTSTSTEEEAIQGMLSMAGLHYSTCLQRQIQSTDCSGERNSLQDPSSCHGSN ENSCPOP00000010087/1-895 EIPVKRECPTSTSTEEEAIQGMLSMAGLHYSTCLQRQMQSTDCSGARNSPEDPSSCPSSN XP_004851336.1/1-942 EIPIKRECPTSTSTEEEAIQGMLSMARLHYSTCLQRQMQSTDCSGARNSPEDPSSFHSSN ***:********************** ****:** ******* :** :**** .** ENSMUSP00000002305/1-940 PEFRQLYRCNKPVEFGYHAKTEDQDLMTSSWNKQFDRTSRFNAQDLSRSQKHIKKESSSE ENSRNOP00000066727/1-843 PEFRQLYRYNKPVEFGYHAKTEDQDLMTSSWNKQFDRTSRFNAQDLSRSQKYIKKESSSE ENSP00000380692/1-941 HEVRQLYRYDKPVECGYHVKTEDPDLRTSSWIKQFD-TSRFHPQDLSRSQKCIRKEGSSE ENSCPOP00000010087/1-895 HEVRQSYRYDKPVECGYHVKTEEQDLRTSSWIKQIDRTSKFNPQDLNRNQKCIKKEGSSE XP_004851336.1/1-942 HEVRQSYRYDKPVEYGYHVKTQDQDLRTSSWIKQIDRTSRFNPQDVSRNQKCNKKEGSSE *.** ** :**** ***.**:: ** **** **:* **:*:.**:.*.** :**.*** ENSMUSP00000002305/1-940 INQKAQSRHCVDSNSSSIQNGKYTLNPSLVS--CQISNGSLSPERPIGETSFSMPLHPTK ENSRNOP00000066727/1-843 ISQKAQSRHCVDSNNSSIQNGKYMLNHSLVS--CQINNGSLSPERPIGETSFSVPLHPTK ENSP00000380692/1-941 ISQRVQSRNYVDSSGSSLQNGKYMQNSNLTSGACQISNGSLSPERPVGETSFSVPLHPTK ENSCPOP00000010087/1-895 ASQKVQSRNCMESSGTGLLSGNCAQNSGVAAGMCQMNSGSVSPERPAGEPSFSVPLHPTK XP_004851336.1/1-942 TSQKVKSRNCMDSNVAGLLNGKYTQNSSMVAGVCQINSGSLSPEMPAGESSFSVPLHPTK .*:.:**: ::*. :.: .*: * .:.: **:..**:*** * **.***:****** ENSMUSP00000002305/1-940 RPASNPPPISNQATKGKRPKKGMATAKQRLGKILKLNRNGHARFFV ENSRNOP00000066727/1-843 RPASNPPPISNQATKGKRPKKGMATAKQRLGKILKLNRNGHARFFV ENSP00000380692/1-941 RPASNPPPISNQATKGKRPKKGMATAKQRLGKILKLNRNGHARFFV ENSCPOP00000010087/1-895 RPASNPPPVSNQATKGKRPKKGMATAKQRLGKILKLNRNGHARFFV XP_004851336.1/1-942 RPASNLPPISNQATKGKRPKKGMATAKQRLGKILKLNRNGHARFFV ***** **:*************************************