CLUSTAL W(1.81) multiple sequence alignment ENSMUSP00000113899/1-1014 MQDAQDSDIGLEGLTPEGTSADRECQRGPETIAHEAQDAGTPNSGDATGVVDGEREATMR ENSRNOP00000028329/1-1040 MQDTQDSDISLEGLTREGAPADRECQRGPETIVHEAQDAGTPNSGDATGAVDGEREATMR ENSP00000347454/1-986 ----------------------------------------------------------MR ENSCPOP00000009891/1-961 ----------------------------------------------------------MR XP_004852224.1/1-996 --------------MEETIPTEEAVRCPLLTKAAGAVDGDGAPPGGPRG-----QAATMR ** ENSMUSP00000113899/1-1014 VPEKYSTLPAEDRSVHIVNICAIEDLGYLPSEGTLLNSLSVDPDAECKYGLYFRDGKRKV ENSRNOP00000028329/1-1040 VPEKYSTLPAEDRSVHIVNICAIEDLGYLPSEGTLLNSLSVDPDAECKYGLYFRDGKRKV ENSP00000347454/1-986 VNEKYSTLPAEDRSVHIINICAIEDIGYLPSEGTLLNSLSVDPDAECKYGLYFRDGRRKV ENSCPOP00000009891/1-961 VHEKYSTLPAEDRSVHIINICAIEDIGYLPSEGTLLNSLSVDPDAKCKYGLYFRDGKRKV XP_004852224.1/1-996 VHEKYSTLPAEDRSVHIINICAIEDIGYLPSEGTLLNSLSVDPDAKCKYGLYFRDGKRKV * ***************:*******:*******************:**********:*** ENSMUSP00000113899/1-1014 DYILVYHHKRASGSRTLARRGLQNDMVLGTRSVRQDQPLPGKGSPVDAGSPEVPMDYHED ENSRNOP00000028329/1-1040 DYILVYHHKRASGSRTLARRGLQNDMVLGTRSVRQDQPLPGKGSPVDVGSPEAPMDYHED ENSP00000347454/1-986 DYILVYHHKRPSGNRTLVRRVQHSDTPSGARSVKQDHPLPGKGASLDAGSGEPPMDYHED ENSCPOP00000009891/1-961 DYILVYHHKRPSGSRALPKRVLHNDAALGARGAKQDQPLPGKGSQVEAGSPEPSVDYHED XP_004852224.1/1-996 DYILVYHHKRPSGSRALPRRVLHNDAALGARSAKQDQPLPGKGGQVEAGSPEPPMDYHED **********.**.*:* :* :.* *:*..:**:******. ::.** * .:***** ENSMUSP00000113899/1-1014 DKRFRREEYEGNLLEAGLELENDEDTKIHGVGFVKIHAPWHVLCREAEFLKLKMPTKKVY ENSRNOP00000028329/1-1040 DKRFRREEYEGNLLEAGLELERDEDTKIHGVGFVKIHAPWHVLCREAEFLKLKMPTKKVY ENSP00000347454/1-986 DKRFRREEYEGNLLEAGLELERDEDTKIHGVGFVKIHAPWNVLCREAEFLKLKMPTKKMY ENSCPOP00000009891/1-961 DKQFRREEYEGNLLEAGLELERDQDTKIHGVGFVKIHAPWNVLCREAEFLKLKMPTKKMY XP_004852224.1/1-996 DKHFRREEYEGNLLEAGLELERDQDTKIHGVGFVKIHAPWNVLCREAEFLKLKMPTKKMY **:******************.*:****************:*****************:* ENSMUSP00000113899/1-1014 HISETRGLLKTINSVLQKITDPIQPKVAEHRPQTTKRLSYPFSREKQHLFDLTDRDSFFD ENSRNOP00000028329/1-1040 HISETRGLLKTINSVLQKITDPIQPKVAEHRPQTTKRLSYPFSREKQHLFDLTDRDSFFD ENSP00000347454/1-986 HINETRGLLKKINSVLQKITDPIQPKVAEHRPQTMKRLSYPFSREKQHLFDLSDKDSFFD ENSCPOP00000009891/1-961 NISETRGLLKTINSVLQKITDPIQPKVAEHRPQTTKRLYYPFSREKQHLFDLSDKDSFFD XP_004852224.1/1-996 HISETRGLLKTINSVLQKITDPIQPKVAEHRPQTTKRLYYPFSREKQHLFDLSDKDSFFD :*.*******.*********************** *** *************:*:***** ENSMUSP00000113899/1-1014 SKTRSTIVYEILKRTTCTKAKYSM----------------------GITSLLANGVYSAA ENSRNOP00000028329/1-1040 SKTRSTIVYEILKRTTCTKAKYSMGQGEGRRKDSALLSKRRKCGKYGITSLLANGVYSAA ENSP00000347454/1-986 SKTRSTIVYEILKRTTCTKAKYSM----------------------GITSLLANGVYAAA ENSCPOP00000009891/1-961 SKTRSTIVYEILKRTTCTKAKYSM----------------------GITSLLANGVYSAA XP_004852224.1/1-996 SKTRSTVVYEILKRTTCTKAKYSM----------------------GITSLLANGVYSAA ******:***************** ***********:** ENSMUSP00000113899/1-1014 YPLHDGDYEGDNVEFNDRKLLYEEWASYGVFYKYQPIDLVRKYFGEKVGLYFAWLGAYTQ ENSRNOP00000028329/1-1040 YPLHDGDYEGDNVEFNDRKLLYEEWASYGVFYKYQPIDLVRKYFGEKVGLYFAWLGAYTQ ENSP00000347454/1-986 YPLHDGDYNGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEKIGLYFAWLGVYTQ ENSCPOP00000009891/1-961 YPLHDGDYEGDNVDFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEKIGLYFAWLGAYTQ XP_004852224.1/1-996 YPLHDGDYEGDNVEFNDRKLLYEEWASYGVFYKYQPIDLVRKYFGEKIGLYFAWLGAYTQ ********:*:**:************ ********************:********.*** ENSMUSP00000113899/1-1014 MLIPASIVGVIVFLYGCATVDENIPSMEMCDQRYNITMCPLCDKTCSYWKMSSACATARA ENSRNOP00000028329/1-1040 MLIPASIVGVIVFLYGCATVDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARA ENSP00000347454/1-986 MLIPASIVGIIVFLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARA ENSCPOP00000009891/1-961 MLIPASIVGIIVFLYGCATVDQNIPSMEMCDQRYNITMCPLCDKTCSYWKMSSACATARA XP_004852224.1/1-996 MLIPASIVGIIVFLYGCATVDQNIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARA *********:*********:*:***********:************************** ENSMUSP00000113899/1-1014 SHLFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRWDLTGFEEEE----DHPRAEYEA ENSRNOP00000028329/1-1040 SHLFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRWDLTGFEEEEVSSCDHPRAEYEA ENSP00000347454/1-986 SHLFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKDHPRAEYEA ENSCPOP00000009891/1-961 SHLFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKDHPRAEYEA XP_004852224.1/1-996 SHLFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRWDLTGFEEEE----DHPRAEYEA *********************************************** ********* ENSMUSP00000113899/1-1014 RVLEKSLRKESRNKE--------------------------TDKVKLTWRDRFPAYFTNL ENSRNOP00000028329/1-1040 RVLEKSLRKESRNKE--------------------------TDKVKLTWRDRFPAYFTNL ENSP00000347454/1-986 RVLEKSLKKESRNKEKRRHIPEESTNKWKQRVKTAMAGVKLTDKVKLTWRDRFPAYLTNL ENSCPOP00000009891/1-961 RVLEKSLRKEFKNKE--------------------------TDKVKLTWKDRFPAYLTNL XP_004852224.1/1-996 RVLEKSLRKESKNKE--------------------------TDKVKLTWKDRFPAYLTNL *******:** :*** ********:******:*** ENSMUSP00000113899/1-1014 VSIIFMIAVTFAIVLGVIIYRISTAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLD ENSRNOP00000028329/1-1040 VSIIFMIAVTFAIVLGVIIYRISTAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLD ENSP00000347454/1-986 VSIIFMIAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLD ENSCPOP00000009891/1-961 VSIIFMIAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLD XP_004852224.1/1-996 VSIIFMIAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLD *********************** ************************************ ENSMUSP00000113899/1-1014 EVYGCIARWLTKIEVPKTEKSFEERLTFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYV ENSRNOP00000028329/1-1040 EVYGCIARWLTKIEVPKTEKSFEERLTFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYV ENSP00000347454/1-986 EVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYV ENSCPOP00000009891/1-961 EVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYV XP_004852224.1/1-996 EVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYV ************************** ********************************* ENSMUSP00000113899/1-1014 YIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKFIRYLKLRRQSP ENSRNOP00000028329/1-1040 YIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKFIRYLKLRRQSP ENSP00000347454/1-986 YIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSP ENSCPOP00000009891/1-961 YIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRRLRRRRQSP XP_004852224.1/1-996 YIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRRLRRRRQSP ************************************************:** *: ::*** ENSMUSP00000113899/1-1014 SDREEYVKRKQRYEVDFNLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIE ENSRNOP00000028329/1-1040 SDREEYIKRKQRYEVDFNLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIE ENSP00000347454/1-986 PDHEECVKRKQRYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIE ENSCPOP00000009891/1-961 SDHEEQGKRKQRYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIE XP_004852224.1/1-996 SDHEEQGKRKQRYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIE .*:** *********:******************************************* ENSMUSP00000113899/1-1014 IRLDAKKFVTELRRPVAIRAKDIGIWYNILRGVGKLAVIINAFVISFTSDFIPRLVYLYM ENSRNOP00000028329/1-1040 IRLDAKKFVTELRRPVAIRAKDIGIWYNILRGVGKLAVIINAFVISFTSDFIPRLVYLYM ENSP00000347454/1-986 IRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYLYM ENSCPOP00000009891/1-961 IRLDAKKFVTELRRPVAVRAKDIGIWYNILRGVGKLAVIINAFVISFTSDFIPRLVYLYM XP_004852224.1/1-996 IRLDAKKFVTELRRPVAVRAKDIGIWYNILRGVGKLAVIINAFVISFTSDFIPRLVYLYM *****************:**************:*************************** ENSMUSP00000113899/1-1014 YSQNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSEHKYDIS ENSRNOP00000028329/1-1040 YSQNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSEHKYDIS ENSP00000347454/1-986 YSKNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDIS ENSCPOP00000009891/1-961 YSQNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSEHKYDIS XP_004852224.1/1-996 YSQNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSEHKYDIS **:***************************************************:***** ENSMUSP00000113899/1-1014 KDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMREEQG ENSRNOP00000028329/1-1040 KDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMREEQG ENSP00000347454/1-986 KDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMREEQD ENSCPOP00000009891/1-961 KDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMREEQG XP_004852224.1/1-996 KDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMREEQG ***********************************************************. ENSMUSP00000113899/1-1014 KQQLLDTWMEKEKPRDV-PCNNHSPTTHPEA-GDGSPVPSYEYHGDAL ENSRNOP00000028329/1-1040 KQQLLDTWMEKEKPRDV-PCNNHSPTAHPEA-GDSSPVPSYEYHGGAL ENSP00000347454/1-986 KQQLLETWMEKERQKDEPPCNHHNTKACPDSLG--SPAPSHAYHGGVL ENSCPOP00000009891/1-961 KQQLLDTWMEKEHAREE-PCNNHTPKACSDSCGSSGPALSHAYHGDAL XP_004852224.1/1-996 KQQLLDTWMEKGHAPED-PCNNHNPKAHSDSCGSSGPAPSHAYCGDAL *****:***** : : ***:*...: .:: * .*. *: * *..*