CLUSTAL W(1.81) multiple sequence alignment ENSMUSP00000130758/1-1068 MAELTNYKDAASNRHLRFKLQSLSRRLDELEEATKNLQRAEDELLDLQDKVIQAEGSDSS ENSRNOP00000016514/1-1073 MADIANYKDAASNRHLRFKLQSLSRRLDELEEATKNLQKAEDELLDLQDKVIQAEGSNSS ENSP00000303758/1-1076 MAEFTSYKETASSRHLRFKLQSLSRRLDELEEATKNLQKAEDELLDLQDKVIQAEGSNSS XP_004850602.1/1-1072 MAEVASYKDTSSSRHLRFKLQSLSRRLDELEEATKNLQKAEDELLDLQDKVIQAEGSNSS ENSCPOP00000009654/1-1021 MAEVASYKDTASSRHLRFKLQSLSRRLDELEEATKNLQKAEDELLDLQDKVIQAEGSNSS **:.:.**:::*.*************************:******************:** ENSMUSP00000130758/1-1068 TLAEIEVLRQRVLKIEGKDEEIKRAEDLCHTMKEKLEEEENLTRELKSEIERLQKRMVDL ENSRNOP00000016514/1-1073 MLAEIEVLRQRVLKIEGKDEEIKRAEDLCHTMKEKLEEEENLTRELKSEIDRLQKRMADL ENSP00000303758/1-1076 MLAEIEVLRQRVLRIEGKDEEIKRAEDLCRLMKEKLEEEENLTRELKSEIERLQKRMAEL XP_004850602.1/1-1072 MLAEIEVLRQQVLRIEGKDEEIKKAEDLCHLMKEKLEEEENLTRELKSEIERLQKRMAEL ENSCPOP00000009654/1-1021 MLAEIEVLRQQVLRIEGKDEEIKRAEDLCHLMKEKLEEEENLTRELKCEIERLQKRMAEL *********:**:*********:*****: ****************.**:******.:* ENSMUSP00000130758/1-1068 EKLEEALSRSKNECSQLCLSLNEERNLTKKISSELEMLRVKVKELESSEDRLDKTEQSLV ENSRNOP00000016514/1-1073 EKLEEALSRSKNECSQLCLSLNEERNLTKKISSELEMLRVKVKELESSEDRLEKTEQSLV ENSP00000303758/1-1076 EKLEEAFSRSKNDCTQLCLSLNEERNLTKKISSELEMLRVKVKELESSEDRLDKTEQSLA XP_004850602.1/1-1072 EKLEEAFSRSKNDCTQLCLSLNEERNLTKKISSELEMLRVKVKELESSEDRLDKTEQNLV ENSCPOP00000009654/1-1021 EKLEEAFSRSKNDCTQLCLSLNEERNLTKKISSELEMLRVKVKELESSEDRLDKTEQNLA ******:*****:*:*************************************:****.*. ENSMUSP00000130758/1-1068 SELEKLKSLTLSFVNERKYLNEKEKENEKIIKELTQKLEQNKKMNRDHMRNASTFLERND ENSRNOP00000016514/1-1073 SELEKLKSLTLSFVNERKYLNEKEKENEKLIKELTQKLEQNKKINRDHMRNASTFLERND ENSP00000303758/1-1076 SELEKLKSLTLSFVSERKYLNEKEKENEKLIKELTQKLEQNKKMNRDYTRNASN-LERND XP_004850602.1/1-1072 SELEKLKSLTLSFVSERKYLNEKEKENEKLIKELTQKLEQNKKMNRDYTRNASNLLERND ENSCPOP00000009654/1-1021 SELEKLKSLTLSFVSERKYLNEKEKENEKLIKELTQKLEQNKKMNRDYTRNASNLLERND **************.**************:*************:***: ****. ***** ENSMUSP00000130758/1-1068 LRIEDGISSTLSSKESKRKGSLDYLKQVENETRDKSENEKNRNQEDNKVKDLNQEIEKLK ENSRNOP00000016514/1-1073 LRIEDGISSTLPSKESRRKGSLDYLKQVENETRDKSENEKNRNQEDNKVKDLNQEIEKLK ENSP00000303758/1-1076 LRIEDGISSTLPSKESRRKGGLDYLKQVENETRNKSENEKNRNQEDNKVKDLNQEIEKLK XP_004850602.1/1-1072 LRIEDGISSALPSKESRRKGALDYLKQVENETRNKSENEKNRNQEDNKVKDLNQEIEKLK ENSCPOP00000009654/1-1021 LRIEDGISSTLPSKESRRKDALDYLKQVENETRNKSENEKNRNQEDNKVKDLNQEIEKLK *********:*.****:**..************:************************** ENSMUSP00000130758/1-1068 TQIKHFESLEEELKKMRAKNNDLQDNYLTELNRNRSLASQLEEIKLQVRKQKELGNGDIE ENSRNOP00000016514/1-1073 TQIKHFESLEEELKKMRAKNNDLQDNYLTELNKNRSLASQLEEVKLQVKKQKELGNGDIE ENSP00000303758/1-1076 TQIKHFESLEEELKKMKSKNNDLQDNYLSEQNKNKLLASQLEEIKLQIKKQKELENGEVE XP_004850602.1/1-1072 TQIKHFESLEEELKKMRAKNSDLQDNYLSEQNKNKILASQLEEIKLQIKKQKQLENGEIE ENSCPOP00000009654/1-1021 TQIKHFESLEEELKKMRAKNNDLQDNYLSEQNKNKILASQLEEIKLQIKKQKELENGEVE ****************::**.*******:* *:*: *******:***::***:* **::* ENSMUSP00000130758/1-1068 GEDAFLLGRGRHERTKLKGHGSEASVSKHTSRELSPQHKRERLRNREFALSNEHYSLSSK ENSRNOP00000016514/1-1073 GEDAFLLGRGRHERTKLKGHGGEVSVSKHTSREQSPQHKRERLRNRGFALNDEHCSLSNK ENSP00000303758/1-1076 GEDAFLSSKGRHERTKFRGHGSEASVSKHTARELSPQHKRERLRNREFALNNENYSLSNR XP_004850602.1/1-1072 REDAFLSSKGRHERTKFRGHGGEACGSKYPSRELSPQHKRERLRNREFALHSENYSVSNR ENSCPOP00000009654/1-1021 GEEVFLSSKGRHERTKFRGLGGEASMAKHASRDLSPQHKRDRLRNRELPLSSEHYTLGSR *:.** .:*******::* *.*.. :*:.:*: ******:***** :.* .*: ::..: ENSMUSP00000130758/1-1068 QASSPVFTNKRAAKASNMGMGTDSGTQETKRTEDRFAPGSSHSEGKRGREQPSVLSRYPP ENSRNOP00000016514/1-1073 QVSSPAFTNKRAAKASNMGVGPDSGTQETKRTEDRLAPGSSQSEGKKGREQPSVLSRYPP ENSP00000303758/1-1076 QVSSPSFTNRRAAKASHMGVSTDSGTQETKKTEDRFVPGSSQSEGKKSREQPSVLSRYPP XP_004850602.1/1-1072 HVSSPTFTSRRVAKASNMVAGTESGAQETKRTEDRFAPGSSQSDGKKAREQPSVLSRYPP ENSCPOP00000009654/1-1021 QVSSPTLTSRRAAKASSVGAGTDSGAQEARRTEDRFAPGSSQSEGKRAREQPSVLSRYPP :.*** :*.:*.**** : ..:**:**:::****:.****:*:**:.************ ENSMUSP00000130758/1-1068 AAQEHTKVWKGAPKPGTESGLKGKVEKTTRTFSDSTHVSVPNDIVGKGDKTSDLSSEAHC ENSRNOP00000016514/1-1073 AAQDHTKVWRGNPKPGTESGLKGKVEKTTRTFSDSAHGSVPNDVVGKGDKTSDFSSEAHC ENSP00000303758/1-1076 AAQEHSKAWKGTSKPGTESGLKGKVEKTTRTFSDTTHGSVPSDPLGRADKASDTSSETVF XP_004850602.1/1-1072 AAQEHSKVWKGTPKPGTESGLKGKVEKTTRTFSNSTHGSVPSDTLDRADKASDTLSEAHF ENSCPOP00000009654/1-1021 AAQEHNKVWKGTPKPGTEGGLKGKVEKTTRTFSNSMLGSVPGDALGRAERASEPSSEAPL ***:*.*.*:* .*****.**************:: ***.* :.:.:::*: **: ENSMUSP00000130758/1-1068 GKRGQVPGHASQGTQAVESSCSKAIGALSSSQKASSEGLSKGKKTANGLAADANFSNSKA ENSRNOP00000016514/1-1073 GKRGQVPGHASQVTQVAESGCSKAIGALASSQRASSEGLSKGKKAANGLETDANFPHSKA ENSP00000303758/1-1076 GKRGHVLGNGSQVTQAANSGCSKAIGALASSRRSSSEGLSKGKKAANGLEADNSCPNSKA XP_004850602.1/1-1072 SKRAQVPDSESQVTPATDHVCSKATGALASSRRSSSEGLSKGKKAANGLEADTGSPTSKA ENSCPOP00000009654/1-1021 GKRGQVLAGGSQLAQATDPACSKAVGALASSRRSSAEGLSKSRKAANGLEADTASPSAKA .**.:* ** : ..: **** ***:**:::*:*****.:*:**** :* . :** ENSMUSP00000130758/1-1068 PILSKYPYSSRSQENILQGFSLPNKEGVDQPVAVVMEDSSQHEALRCRVIKSSGREKPDS ENSRNOP00000016514/1-1073 PILSKYPYSSRSQENILQGFSVPNKEGVDHSVAVVMEDSSQHEALRCRVIKSSGREKPDS ENSP00000303758/1-1076 PVLSKYPYSCRSQENILQGFSTSHKEGVNQPAAVVMEDSSPHEALRCRVIKSSGREKPDS XP_004850602.1/1-1072 SILSKYPYSSRSQENILQGFSTPNKE-VEQPVAVVMEDSSHHEALRCRVIKSSGGEKPDS ENSCPOP00000009654/1-1021 PILSKYPYSSRSQENILQGFSAAHKE-AEQSIAVVMEDSSQHEALRCRVIKSSGRENPDS .:*******.*********** .:** .::. ******** ************* *:*** ENSMUSP00000130758/1-1068 DDDLDIESFVTAKLVNTTITPEPEPKPQPNSREKVKSRGGTRTALFENDKNAAIENDSVK ENSRNOP00000016514/1-1073 DDDLDIESLVTAKLVNTTITPEPEPKLQPNSREKVKSRGGTRTALFENDKNAAVENDSAK ENSP00000303758/1-1076 DDDLDIASLVTAKLVNTTITPEPEPKPQPNSREKAKTRGAPRTSLFENDKDAGMENESVK XP_004850602.1/1-1072 DDDLDMASLVTAKLVNTTITPEPEPKLPPTPREKAKSRGEHRISRFENDKNTGIESESVK ENSCPOP00000009654/1-1021 DDDLDTASLVTAKLVNTTITPEPEPKLPPNSREKAKARGEHRTSLFENDKNGGIENESVK ***** *:***************** *..***.*:** * : *****: .:*.:*.* ENSMUSP00000130758/1-1068 PTRPSSNAIEFPDANCAGVKNQRPFSPREALRSRAIIKPVIIDKDVKKIMGGSGTEVVLE ENSRNOP00000016514/1-1073 SMRSSSNAVEFPDANCAGVKNQRPFSPREALRSRAIIKPVIIDKDVKKIMGGSGTEVVLE ENSP00000303758/1-1076 SVRASTNTMELPDTNGAGVKSQRPFSPREALRSRAIIKPVIVDKDVKKIMGGSGTETTLE XP_004850602.1/1-1072 PVRASSNAVELADANGAGVKSQRPFSPREALRSRGVIKPVIIDKNVKKIMGGSGTEAVLE ENSCPOP00000009654/1-1021 PVRGSSNSMELPDASRAGVKSQRPFSPREALRSRGVIKPVIIDKNVKKIMGGSGTEAVLE . * *:*::*:.*:. ****.*************.:*****:**:***********..** ENSMUSP00000130758/1-1068 KQKSTSKSVTSKVTSSITIYPSDSSGPRAVPSEAPRERHTSTSNIQVGPPELTAISNHVS ENSRNOP00000016514/1-1073 KQKSTPKSVTSKVTSSITIYPSDSSGPRAVPTEAPRERHTSTSNIQVGPPELTSVSNHIS ENSP00000303758/1-1076 KQKPVSKPGPNKVTSSITIYPSDSSSPRAAPGEALRERHTSTSNIQVGLAELTSVSNHVS XP_004850602.1/1-1072 KQKLTSKPGPNKVTSSITIYPCDSSSPRAGPGEALRERHTSTSNIQVGPAELMPVSNHVS ENSCPOP00000009654/1-1021 KQKSSCKPGPNKVTSSITIYPSDSSSPRASPGETPRERHTSTSNIQVGPPELIPVSNHVS *** *. ..**********.***.*** * *: ************* .** .:***:* ENSMUSP00000130758/1-1068 SPLELSIHKHDITLQLTEAERVGDGSPKNRAEMVVSRSSILIKPSESVEKNSHVPPAETI ENSRNOP00000016514/1-1073 SPLELSIHKHDITLQLTEAERVGDGSPKNRAETVVSRSSILIKPSDSVERNSHAFPAETI ENSP00000303758/1-1076 SPFELSIHKHDITLQLAEAERMADGPLKDRPETVVSRSSIIIKPSDPVERNSHAPPAETI XP_004850602.1/1-1072 SPFELSIHKHDITVQLTEAERLGDGSSKNRPDMVVSRSSILIKPSDSVERNSHAAPAETI ENSCPOP00000009654/1-1021 SPLEFSIHKHDIGVQLADAERLGDGPSKNRPDTVVSRSSILIKPSDSVERNSHAAPAETI **:*:******* :**::***:.**. *:*.: *******:****:.**:***. ***** ENSMUSP00000130758/1-1068 RWKSHSA-----SSDSRHITVRNAWKSKRDLKCSEDPPTGIGRNMEAT--NAYTQRPCTD ENSRNOP00000016514/1-1073 RWKSHSTSSEVASSDTRHITVRNAWKSKRDLKCSEDPPTRIGRNVEAT--NAYTQRSSTD ENSP00000303758/1-1076 RWKSHSAPSEVGFSDARHVTVRNAWKSRRDLKSLEDPPTRIGKNVESTNSNAYTQRSSTD XP_004850602.1/1-1072 RWKSHSTPSEGGSSDTRHITVRNAWKTKEDLKSFEDAPTQVGRNMEST--NTYIQRSSTD ENSCPOP00000009654/1-1021 RWKSHSAPSEVGSSDARHVTVRNAWKSKRDLKSLEDPPTQAGRNMGPS--TTHIQRSSTD ******: **:**:*******::.***. **.** *:*: .: .:: **..** ENSMUSP00000130758/1-1068 FLELEQPRSQPSEQGARRVG-NSGDAPELSPRRTQSSLTASEVLTRRDRMGGAITAASCN ENSRNOP00000016514/1-1073 FLELEQPRSHPPEQGTRKVG-NSGDAPELSSRRTQSSLTASEVLTRRNRIGDAVTAASWN ENSP00000303758/1-1076 FSELEQPRSCLFEQGTRRVGPSSGDAPEPSSRRTQSSLTVSEVLTRRNRVGDTITVAAWN XP_004850602.1/1-1072 FSELEQPRSYLSESGIRRVG-NSGDAAELSSRRTQSSLTVSEVLTHRSRAGDRVMAAAWN ENSCPOP00000009654/1-1021 FSELEQPRSYLSESGPRKVG-NSGDAAELSSRRTQSSLTVSEVLTHRSRAGDTVLAAAWN * ******* *.* *:** .****.* *.********.*****:*.* *. : .*: * ENSMUSP00000130758/1-1068 HSSSM-EEGEDSTFVTSRRIHNPLEHSELPGKQGLPEPEPVWTEERLHPAKPYAEED ENSRNOP00000016514/1-1073 HSSNV-EEGEDSTFVSSRRVHNPLEHSEPPGKQGLPESERVWTEERLHPARPYAEED ENSP00000303758/1-1076 HSASMEEEGEDCTLSVYRQLHNSLDPSELPGKQGLPESGRVRAEERLRPTRPCAEEN XP_004850602.1/1-1072 HSAGM-EEGEDCALSVHRRLHNSLEQSEWPVKPGLPELGRVRAEERLRPSRPCAEEN ENSCPOP00000009654/1-1021 HSAGM---------------------------------------------------- **:.: