CLUSTAL W(1.81) multiple sequence alignment ENSCPOP00000009615/1-564 ------------------------------------------------------------ ENSP00000455041/1-758 MSESSGSALQPGR-PSRQPAVHPENLSLDSSCFSSPPVNFLQELPSYRSIARRRTTVHSR XP_004855860.1/1-614 ------------------------------------------------------------ ENSMUSP00000046927/1-726 --MSEGSAGDPGHGSSRQRAVHPENLSLGSSCF-SPPVNFLQELPSYRSVARRRTNILSR ENSRNOP00000022800/1-726 --MSEGNAGDPGHGSSRQRAVHPENLSLGPSCF-SPPVNFLQELPSYRSVARRRTNILSR ENSCPOP00000009615/1-564 ------------------------------------------------------------ ENSP00000455041/1-758 DKQSGTLLKPTDSYSSQLEDRIAENLSSHSLRNYALNISEKRRLRDIQETQMKYLSEWDQ XP_004855860.1/1-614 ---------------------------------------------------MKYLSEWDQ ENSMUSP00000046927/1-726 DKQSGTLLKPTDSFSCQLDGGITENLNSQSIRKYALNISEKRRLRDIQETQMKYLSEWDQ ENSRNOP00000022800/1-726 DKQSGTLLKPTGSFSSQLDGGITENLNSQSIRKYALNISEKRRLRDIQETQMKYLSEWDQ ENSCPOP00000009615/1-564 ----------------------------------GKFGTGIQSYFSFLRFLVLLNSVIFL ENSP00000455041/1-758 WKRYSSKSWKRFLEKAREMTTHLELWREDIRSIEGKFGTGIQSYFSFLRFLVLLNLVIFL XP_004855860.1/1-614 WKQYSSKSWKRFSEKAREVTRHLELWREDIRSIEGKFGTGIQSYFSFLRFLVLLNLVIFL ENSMUSP00000046927/1-726 WKRYSSKSWKRFLEKAREMTTHLELWRKDIRSIEGKFGTGIQSYFSFLRFLVVLNLVIFL ENSRNOP00000022800/1-726 WKRYSSKSWKRFIEKAREMTTHLELWRKDIRSIEGKFGTGIQSYFSFLRFLVVLNLVIFL ******************:** **** ENSCPOP00000009615/1-564 IIFMLVLLPECLGGANVTPSTPV-TSYK----QCTVYPGSSSGLIYFYSYIIDLLSGTGF ENSP00000455041/1-758 IIFMLVLLPVLLTKYKITNSSFVLIPFKDMDKQCTVYPVSSSGLIYFYSYIIDLLSGTGF XP_004855860.1/1-614 IIFVLVLLPVLLTSYKFTNSTFVLIPLKDMDMQCTIHPVSTSGLIYFYSYIIDLLSGSGF ENSMUSP00000046927/1-726 IIFMLVLLPILLTKYKITNSTFVLIPFKDMDIQCTLYPISSSGLIYFYSYIIDLLSGTGF ENSRNOP00000022800/1-726 IIFMLVLLPIILTKYKITNSTFVLIPFKDMDMQCTLYPISSSGLIYFYSYIIDLLSGTGF ***:***** * :.* *: * . * ***::* *:****************:** ENSCPOP00000009615/1-564 LEETYLFYGHYTI---------Y---VPHLFSNTPCLCFGIYFICCVXVIDIACTGETGL ENSP00000455041/1-758 LEETSLFYGHYTIDGVKFQNFTYDLPLAYLLSTIASLALSLLWIVKRSV--------EGF XP_004855860.1/1-614 LEETSLFYGHYTIDGIKFQNFTYDLPLAYLISTIAYLVLSLLWIVKRSV--------EGF ENSMUSP00000046927/1-726 LEETSLFYGHYTIDGVKFQSFTYDLPLAYLISTIAYLALSLLWIVKRSV--------EGF ENSRNOP00000022800/1-726 LEETSLFYGHYTIDGVKFQNFTYDLPLAYLISTIAYLALSLLWIVKRSV--------EGF **** ******** * :.:*:*. . * :.: :* * *: ENSCPOP00000009615/1-564 KVGDYERLKWKEHKKVQIDE--EGIIGFC-PLKLLHYTAHKCIFFAPQADLEEERIRQKI ENSP00000455041/1-758 KI---NLIRSEEHFQSYCNKIFAG-WDFCITNRSMADLKHSSLRYELRADLEEERMRQKI XP_004855860.1/1-614 KV---NLIRSEEHFQSYCNKIFAG-WDFCITSRSMADLKHSSLRYELRADLEEERIRQKI ENSMUSP00000046927/1-726 KI---NLIRSEEHFQSYCNKIFAG-WDFCITNRSMAELKHSSLRYELRADLEEERIRQKI ENSRNOP00000022800/1-726 KI---NLIRSEEHFQSYCNKIFAG-WDFCITNRSMAELKHSSLRYELRADLEEERIRQKI *: : :: :** : :: * .** . : : *..: : :*******:**** ENSCPOP00000009615/1-564 AQRTSEETIRIYSLRLLLNCIVLAVLAACFYAIYLATIFSQEHMNLPEIAEIGKMVFGEN ENSP00000455041/1-758 AERTSEETIRIYSLRLFLNCIVLAVLGACFYAIYVATVFSQEHMK----KEIDKMVFGEN XP_004855860.1/1-614 AQRTSEETIRIYSLRLFLNCIVLAVLAACFYAIYLATTFSQGHMK----KEIDKMVFGEN ENSMUSP00000046927/1-726 AERTSEETIRIYTLRLFLNCIVLAVLAACFYAIYLATAFSQEHMK----KEIDKMVFGEN ENSRNOP00000022800/1-726 AERTSEETIRIYSLRLFLNCIVLAVLAACFYAIYLATTFSQEHMK----KEIDKMVFGEN *:**********:***:*********.*******:** *** **: **.******* ENSCPOP00000009615/1-564 LLILYLPSIVITLANFITPIIFAKIIHYEDYSPGFEIRLTILRCVFMRLATICVLVFTLG ENSP00000455041/1-758 LFILYLPSIVITLANFITPMIFAKIIRYEDYSPGFEIRLTILRCVFMRLATICVLVFTLG XP_004855860.1/1-614 LLILYLPSIVITLANFITPIIFAKIIHYEDYSPGFEIRLTILRCVFMRLATICVLVFTLG ENSMUSP00000046927/1-726 LLILYLPSIVITLANFITPIIFAKIIHYEDYSPGFEIRLTILRCVFMRLATICVLVFTLG ENSRNOP00000022800/1-726 LLILYLPSIVITLANFITPIIFAKIIHYEDYSPGFEIRLTILRCVFMRLATICVLVFTLG *:*****************:******:********************************* ENSCPOP00000009615/1-564 SKITSCDDTTCELCGYNQKLYPCWETQVGQEMYKLMIFDLIIILAVTLFVDFPRKLLVTY ENSP00000455041/1-758 SKITSCDDDTCDLCGYNQKLYPCWETQVGQEMYKLMIFDFIIILAVTLFVDFPRKLLVTY XP_004855860.1/1-614 SEITSCDDNTCELCGYNQKLYPCWETQVGQEMYKLMIFDFIIILAVTLFVDFPRKLLVTY ENSMUSP00000046927/1-726 SKITSCGDSTCELCGYNQKLYPCWETQVGQEMYKLMIFDFIIILAVTLFVDFPRKLLVTY ENSRNOP00000022800/1-726 SKITSCGDSTCELCGYNQKLYPCWETQVGQEMYKLMIFDFIIILAVTLFVDFPRKLLVTY *:****.* **:***************************:******************** ENSCPOP00000009615/1-564 CSSWKLIQCWGQQEFAIPDNVLGIVYGQTICWIGAFFSPLLPAIATAKFIIIFYVKELSL ENSP00000455041/1-758 CSSCKLIQCWGQQEFAIPDNVLGIVYGQTICWIGAFFSPLLPAIATLKFIIIFYVKEWSL XP_004855860.1/1-614 CSSWKLIQCWGQQEFAIPDNVLGIVYGQTICWIGAFFSPLLPAIATLKFIIIFYVKELSL ENSMUSP00000046927/1-726 CASSKLIQCWGQQEFAIPDNVLGIVYGQTICWIGAFFSPLLPAIATLKFVIIFYVKELSL ENSRNOP00000022800/1-726 CASSKLIQCWGQQEFAIPDNVLGIVYGQTICWIGAFFSPLLPAIATLKFVIIFYVKELSL *:* ****************************************** **:******* ** ENSCPOP00000009615/1-564 LYTCKPSPRQFRASNSNFFFLLVLLIGLCLAIIPLTVSMSSIPSSKACGPFTNYNTTWEV ENSP00000455041/1-758 LYTCRPSPRPFRASNSNFFFLLVLLIGLCLAIIPLTISISRIPSSKACGPFTNFNTTWEV XP_004855860.1/1-614 LYTCRPSPRQFRASNSNFFFLLVLLIGLCLAIIPLTISMSRIPSSKACGPFTNYNTTWEV ENSMUSP00000046927/1-726 LYTCRPSPRQFRASNSNFFFLLVLLIGLCLAIIPLTISMARIPSSKACGPFTNFNTTWEV ENSRNOP00000022800/1-726 LYTCRPSPRQFRASNSNFFFLLVLLIGLCLAIIPLTISMARIPSSKACGPFTNFNTTWEV ****:**** **************************:*:: ************:****** ENSCPOP00000009615/1-564 IPSTVTTFPSSLQSVIHGITSEAFAVPFFMIICLIMFYFIALAGAHKRVVMQLREQLSLE ENSP00000455041/1-758 IPKTVSTFPSSLQSFIHGVTSEAFAVPFFMIICLIMFYFIALAGAHKRVVIQLREQLSLV XP_004855860.1/1-614 IPKTVTTFPSSLQSVIHGITSEAFAVPFFMIICLIMFYFIALAGAHKQVVIQLREQLSLE ENSMUSP00000046927/1-726 IPQTVSTFPSSLQTLIHAVTSEAFAVPFFMIICLVMFYFIALAGAHKQVVVQLREQLSLE ENSRNOP00000022800/1-726 IPQTVSTFPSSLQTLIHGVTSEAFAVPFFMIICLVMFYFIALAGAHKRVVAQLREQLSLE **.**:*******:.**.:***************:************:** ******** ENSCPOP00000009615/1-564 SRDK------------------------RYLIQKLTEAQQDL------------- ENSP00000455041/1-758 RKHSSRGSWLGTFTQDTARKVLFSWEGVKLLQPSLTTTSPKLCLEAQPRPASLIH XP_004855860.1/1-614 SRDK------------------------RYLIQKLTEAQQDL------RDQ---- ENSMUSP00000046927/1-726 SRDK------------------------RYLIQKLTEAQREV------RSQPASA ENSRNOP00000022800/1-726 SRDK------------------------RYLIQKLTEAQRDV------RSQPALA :.. : * .** :. .: