CLUSTAL W(1.81) multiple sequence alignment ENSMUSP00000086027/1-757 MSGNNLSGNDEFDEQLRMQELYGGDPKEGDTQNEPSGEAHSLGQPPDDTPYEWDLDKKAW ENSRNOP00000061583/1-776 MSGSNLSGNDEFDEQLRMQELY-GDPKEGDTQNEPSGETDSLGQPPDDTPYEWDLDKKAW ENSP00000218364/1-755 MSGTNLDGNDEFDEQLRMQELY-GDGKDGDTQTDAGGEPDSLGQQPTDTPYEWDLDKKAW ENSCPOP00000009423/1-628 MSGTNLN-DDEFDEHFRMQELY-GD-KDGDIHKDPSGETESFGQPPADTPYEWDLDKRAW XP_004862389.1/1-754 MSGSNLNKNDEFDEQLRMQELY-GDTKDSDTENDPSEETESFGQQAADTPYEWDLDKKAW ***.**. :*****::****** ** *:.* ..:.. *..*:** . **********:** ENSMUSP00000086027/1-757 FPKITEDFIATYQANYGFSSDGASSSTANVQDANTKAVEEPPQKEVPETPDSKRKGEKRK ENSRNOP00000061583/1-776 FPKITEDFIASYQANYGFSGDGAPSSTGNVQDANTKTVEEPPQKEIPETTDSKKRGEKRK ENSP00000218364/1-755 FPKITEDFIATYQANYGFSNDGASSSTANVEDVHARTAEEPPQEKAPEPTDARKKGEKRK ENSCPOP00000009423/1-628 FPKITEDFIATYQANYGFTSDGASGSTEHVSDTSMRTAEEPPQRKTPEPTDPKKRGEKRK XP_004862389.1/1-754 FPKITEDFIATYQANYGFCSDGASSSTAHVPDTSMRTAKDLPQGKTPEPTEPRKKGEKRK **********:******* .***..** :* *. ::.:: ** : **..:.:::***** ENSMUSP00000086027/1-757 AESGWFHVEEDRNTNVYVSGLPPDITVDEFIQLMSKFGIIMRDPQTEEFKVKLYKDDQGN ENSRNOP00000061583/1-776 AESGWFHVEEDRNTNVYVSGLPPDITVDEFIQLMSKFGIIMRDPQTEEFKVKLYKDDQGN ENSP00000218364/1-755 AESGWFHVEEDRNTNVYVSGLPPDITVDEFIQLMSKFGIIMRDPQTEEFKVKLYKDNQGN ENSCPOP00000009423/1-628 GDSGWFHVEEDRNTNVYVSGLPPDITVDEFIQLMSKFGIIMRDPQTEEFKVKLYKDNQGN XP_004862389.1/1-754 GESGWFHVEEDRNTNVYVSGLPPDITVDEFIQLMSKFGIIMRDPQTEEFKVKLYKDNQGN .:******************************************************:*** ENSMUSP00000086027/1-757 LKGDGLCCYLKKESVELALKLLDEDEIRGYKLHVEVAKFQLKGEYDASKKKKKCKDYKKK ENSRNOP00000061583/1-776 LKGDGLCCYLKKESVELALKLLDEDEIRGYKLHVEVAQFQLKGEYDASKKKKKCKDYKKK ENSP00000218364/1-755 LKGDGLCCYLKRESVELALKLLDEDEIRGYKLHVEVAKFQLKGEYDASKKKKKCKDYKKK ENSCPOP00000009423/1-628 LKGDGLCCYLKRESVELALKLLDEDEIRGYKLHVEVAKFQLKGEYDASKKKKKCKDYKKK XP_004862389.1/1-754 LKGDGLCCYLKRESVELALKLLDEDEIRGYKLHVEVAKFQLKGEYDASKKKKKCKDYKKK ***********:*************************:********************** ENSMUSP00000086027/1-757 LSLQQKQLDWRPERRAGPNRLRHERVVILKNMFHPMDFEDDPLVLNEIREDLRVECSKFG ENSRNOP00000061583/1-776 LSLQQKQLDWRPERRAGPNRLRHERVVILKNMFHPMDFEDDPLVLNEIREDLRVECSKFG ENSP00000218364/1-755 LSMQQKQLDWRPERRAGPSRMRHERVVIIKNMFHPMDFEDDPLVLNEIREDLRVECSKFG ENSCPOP00000009423/1-628 LSLQQKQLDWRPERRAGPSRMRHERVVIIKNMFHPEDFEDDPLVLNEIREDLRVECAKFG XP_004862389.1/1-754 LSVQQKQLDWRPERRAGPSRMRHERVVILKNMFHPTDFEDDPLVLNEIRDDLRVECSKFG **:***************.*:*******:****** *************:******:*** ENSMUSP00000086027/1-757 QIRKLLLFDRHPDGVASVSFREPEEADHCIQTLDGRWFGGRQITAQAWDGTTDYQVEETS ENSRNOP00000061583/1-776 QIRKLLLFDRHPDGVASVSFREPEEADNCIQTLDGRWFGGRQITAQAWDGTTDYQVEETS ENSP00000218364/1-755 QIRKLLLFDRHPDGVASVSFRDPEEADYCIQTLDGRWFGGRQITAQAWDGTTDYQVEETS ENSCPOP00000009423/1-628 QIKKLLLFDRHPDGVASVSFRDAEEADHCIQTLDGRWFGGRQITAQAWDGTTDYQVEETS XP_004862389.1/1-754 QIKKLLLFDRHPDGVASVSFRDPEEADHCIQTLDGRWFGGRQITAQPWDGTTDYQVEETA **:******************:.**** ******************.************: ENSMUSP00000086027/1-757 REREERLRGWEAFLNAPEASRGLRRMDSIAGSERPGPSRMRHFSEHPSMSNMKAQEATTG ENSRNOP00000061583/1-776 REREERLRGWEAFLNAPEANRGLQRMDSICGSERPGPSRVRHFSEHPSMSNMGAQEATTG ENSP00000218364/1-755 REREERLRGWEAFLNAPEANRGLRRSDSVSASERAGPSRARHFSEHPSTSKMNAQETATG ENSCPOP00000009423/1-628 REREERLKGWEAFLNAPEANRSLQRSDSVSASEMAGPSRARHFSEPPSTWKMNAQEAETG XP_004862389.1/1-754 REREERLKGWEAFLSTPEANRGLRRSDSVSASEMAGPSRMRHFSEGPSTLKMNAQEAETG *******:******.:***.*.*:* **:..** .**** ***** ** :* ***: ** ENSMUSP00000086027/1-757 MAFEETIDENKFEKAE-EGGESEGDASEKDAKEGGSDGD------------------HPE ENSRNOP00000061583/1-776 MAFEETIDENKFEKAEDDGGESEGDASEKDAKEGESDGDYPERESDEGCSKRQCEEGCPD ENSP00000218364/1-755 MAFEEPIDEKKFEKTE-DGGEFEEGASENNAKESSPEKE--------------AEEGCPE ENSCPOP00000009423/1-628 MVFEEPVDEKKFEKTE-DRREFEEDASGKDPKEG-------------------------- XP_004862389.1/1-754 MVFEEPINEKKFEKTE-DGGEFEEDAYEEDTKEGELEKE--------------SKDDCPE *.***.::*:****:* : * * .* ::.**. ENSMUSP00000086027/1-757 REGGEGCSKKENEEGCPERALEPEEGNPQTEAQENGPEREARKK-SKMDYEKNGFSKESE ENSRNOP00000061583/1-776 RESGEGCSKRESGEGCPERELELEEGNPKKESQENGPERESKKK-GKENYEKNGLAKESE ENSP00000218364/1-755 KESEEGCPKRGFEGSCSQK--ESEEGNPVRGSEEDSPKKESKKKTLKNDCEENGLAKESE ENSCPOP00000009423/1-628 ---------------------------------KHGSKRESTKKILGKTCEENGLASESE XP_004862389.1/1-754 KESEEGCPEREAGGDCPEK--EFEEGSPGKELKKNGSKRESKKR-LKKGDEESSLANKSE :...::*: *: *:..::.:** ENSMUSP00000086027/1-757 DNDLGKESEGEDSLKKESEDDDSEEESEEDSSEKQ----SQDGSDKEIEENGVKKDVDQD ENSRNOP00000061583/1-776 DNDLNRESEGEDSPKKESEEDDSERESEEDSSEKQ----SENGSDKELEENGVKKDFDQD ENSP00000218364/1-755 D-DLNKESEEEVGPTKESEEDDSEKESDEDCSEKQ----SEDGSEREFEENGLEKDLDEE ENSCPOP00000009423/1-628 DDDANPGSKEEGSPQKESEEDDSERESDEDHSEKQ----SEDGSEKELEENGVEQDFDEE XP_004862389.1/1-754 VDDADKESKGESSPQKESEEDDSEKESDEDCLEKQSENSSENSSEEELEENGVKQDFDED * . *: * . ****:****.**:** *** *::.*:.*:****:::*.*:: ENSMUSP00000086027/1-757 VSDKEFPEDV-EKESEENETDKSEF-DEGSERVLDEEGSEREFEEDSDEKEEEGDDDEE- ENSRNOP00000061583/1-776 ASDKEFPENV-EKESEENETDKSEF-DEGSERVLGEEGSEREFEEDSDEKEEEEDDDEEK ENSP00000218364/1-755 GSEKELHENVLDKELEENDSENSEFEDDGSEKVLDEEGSEREFDEDSDEKEEEEDT---- ENSCPOP00000009423/1-628 GSDRDFPENLFDKELEEYDTDKSEF--EDTERMLDVEDSEREFDEESDEKDDEET----- XP_004862389.1/1-754 GSDKEFPENLLDRELEENDTDNSEF--EGSERVLDMEDSEREFDEESDEKDEEET----- *:::: *:: ::* ** ::::*** :.:*::*. *.*****:*:****::* ENSMUSP00000086027/1-757 EVVYERVFDDDSDDIEEEEEADEKECEDADDKEEDNDIDEKLFDDSDEKEDEEDTDGKKD ENSRNOP00000061583/1-776 EVVYERVFEDDSDDFEEEEEAYEKECEDADEKEEDDDVDEKVFDDSDEKEDEEDTDVRKD ENSP00000218364/1-755 ---YEKVFDDESDEKEDEEYADEKGLEAADKKAEEGDADEKLFEESDDKED-EDADGKEV ENSCPOP00000009423/1-628 ---YDQVFDDE------------------------------------------------- XP_004862389.1/1-754 ---YEKVFDDESDEKEDEEDVDGKWHEDADVKEED-DTDEKLFEDSDEKEDKEDADGKEG *::**:*: ENSMUSP00000086027/1-757 DDASDKVFE-DNSNEKLFDEEEGPNEKLFDDSDERGTVGNV--KEDGSQSTDSSFALSSS ENSRNOP00000061583/1-776 DDASDKVFE-DNSNEKLFNEEEGPNEKLFDDSDERGTVGNV--KEDGSQSTDSSFALSSS ENSP00000218364/1-755 EDADEKLFEDDDSNEKLFDEEEDSSEKLFDDSDERGTLGGFGSVEEGPLSTGSSFILSS- ENSCPOP00000009423/1-628 --------EDDNSIEK-FDEVSFG-EKEFDDGDDSGTLGNV--MEE-------------- XP_004862389.1/1-754 EDVDEKLFEDDNSLEK-FDEEESSIEKIFDDSDERGTLENV--KEEGLLSTGSSLFLSSD * *:* ** *:* . ** ***.*: **: .. *: ENSMUSP00000086027/1-757 DDDDDEV ENSRNOP00000061583/1-776 DDDGDEV ENSP00000218364/1-755 DDDDDDI ENSCPOP00000009423/1-628 ------- XP_004862389.1/1-754 DDSDDDI