CLUSTAL W(1.81) multiple sequence alignment ENSP00000369121/1-1167 MPNSVLWAVDLFGRVYTLSTAGQYWEMCKDSQLEFKRVSATTQCCWGIACDNQVYVYVCA ENSMUSP00000082844/1-1166 MPTSVLWAVDLFGRVYTLSTAGQYWELCKDVQLEFKRVSAATQCCWGIAGDNQVYLYVCS ENSRNOP00000001347/1-1166 MPTSMLWAVDLFGRVYTLSTAGQYWELCKDVQLEFKRVSAATQCCWGIACDNQVYLYVCS XP_004840530.1/1-1166 MPASVLWAVDLFGRVYTLSTAGQYWQLCRDAQLEFKRLSAATQCCWGIAGDNQVYLYVGA ENSCPOP00000009366/1-1158 MPTSVLWAVDLFGRVYTLSTAGQYWELCRDTQLEFKRVSAATQCCWGIACDNQVYLYMCA ** *:********************::*:* ******:**:******** *****:*: : ENSP00000369121/1-1167 SDVPIRRREEAYENQRWNPMGGFCEKLLLSDRWGWSDVSGLQHRPLDRVALPSPHWEWES ENSMUSP00000082844/1-1166 SDVPIRHREEAYENQRWNPMGGFCEKLLPSDRWPWSDVSGLQHRPLDGVALPSPHWEWES ENSRNOP00000001347/1-1166 SDVPIRHREEAYENQRWNPMGGFCEKLLPSDRWSWSDVSGLQHRPLDGVALPSPYWEWES XP_004840530.1/1-1166 SDVPIRRREETYENQRWNPMGGFCEKLLPSDRWPWSDVSGLQHRLLDGVALPSPHWEWES ENSCPOP00000009366/1-1158 SDVSIRCREEAYENQRWNPMGGFCEKLLPSDRWAWSDVSGLQHRPLDGVALPSPHWEWES ***.** ***:***************** **** ********** ** ******:***** ENSP00000369121/1-1167 DWYVDENFGGEPTEKGGWTYAIDFPATYTKDKKWNSCVRRRKWIRYRRYKSRDIWAKIPS ENSMUSP00000082844/1-1166 DWYVDENFGGEPTEKGGWTYAMDFPATYTRDKKWNSCVRRRKWIRYRRYKSRDSWAKIPS ENSRNOP00000001347/1-1166 DWYVDENFGGEPTEKGGWTYAMDFPATYTRDKKWNSCVRRRKWIRYRRYKSRDTWAKIPS XP_004840530.1/1-1166 DWYVDENFGGEPTEKGGWTYAIDFPATYTRDKKWNSCVRRRKWIRYRRYKSRDVWAKIPS ENSCPOP00000009366/1-1158 DWYVDENFGGEPTEKGGWTYAIDFPATYTRDKKWNSCVRRRKWIRYRRYKSRDAWAKIPS *********************:*******:*********************** ****** ENSP00000369121/1-1167 KDDPKELPDPFNDLSVGGWEITEEPVGRLSVWAVSLQGKVWYREDVSHSNPEGSSWSLLD ENSMUSP00000082844/1-1166 KDDPKELPDPFNDLSVGGWEITEEPVGRLSVWAVSLQGKVWYREDVSHPNPEGSSWSLVE ENSRNOP00000001347/1-1166 KDDPKELPDPFNDLSVGGWEITEEPVGRLSVWAVSLQGKVWYRENVSHPNPEGSSWSLVD XP_004840530.1/1-1166 KDDPKDLPDPFSDLSVGGWEITEEPVGRLSVWAVSLQGKVWYREDVSHPNPEGSSWSLVD ENSCPOP00000009366/1-1158 KDDVKDLPDPFNDLSVGGWEITEEPVGRLSVWAVSLQGKVWYREDVSHPNPEGSSWSLVD *** *:*****.********************************:***.*********:: ENSP00000369121/1-1167 TPGEVVQISCGPHDLLWATLWEGQALVREGINRSNPKGSSWSIVEPPGSENGVMHISVGV ENSMUSP00000082844/1-1166 TPGEVVQISCGPHDLIWATLWEGQALVREGVCRNNPKGSYWSMVEPPGSENGIMHVSAGV ENSRNOP00000001347/1-1166 TPGEVVQISCGPHDLIWATLWEGQALVREGICRNNPKGNSWSIVEPPGSENGIMHVSAGV XP_004840530.1/1-1166 TPGEAVQISCGPHDLLWVTLWEGQALVREGINRNNPKGSSWSVVEPPGAGNGITHVSAGV ENSCPOP00000009366/1-1158 TPGEAVQISCGPHDLLWVTLWEGQALVREGINRNNPKGSSWSVVEPPGSENGIMHVSAGV ****.**********:*.************: *.****. **:*****: **: *:*.** ENSP00000369121/1-1167 SVVWAVTKDWKVWFRRGVNSHNPCGTSWIEMVGEMTMVNVGMNDQVWGIGCEDRAVYFRQ ENSMUSP00000082844/1-1166 SVVWAITKDRKVWFRRGVNSHNPCGTSWIEMVGEMTMVNVGLNDQVWGISCEDRAVYFRQ ENSRNOP00000001347/1-1166 SVVWAITKDRKVWFRRGVNSHNPCGTSWIEMVGEMTMVNVGLNDQVWGISCEDRAVYFRQ XP_004840530.1/1-1166 SVVWAVTKDRKVWFRRGVNSHNPCGTSWLEMVGEMTMVNVGLNDQVWGIGCEERVVYFRQ ENSCPOP00000009366/1-1158 SVVWAVTKDRKVWFRRGVNSHNPGGTSWIEMVGEMTMVNVGLNDQVWGIGAEERAVYFRQ *****:*** ************* ****:************:*******..*:*.***** ENSP00000369121/1-1167 GVTPSELSGKTWKAIIAARECDRSHSGSSSSLLSAGCFFGDEVRGSG-ESAPSDTDASSE ENSMUSP00000082844/1-1166 GVTPSELSGKTWKAIVVGRESDRSHSGSSSSLLSAGCFFGDEVRGSGTESAPSDTDASLE ENSRNOP00000001347/1-1166 GVTPSELSGKTWKAIVVGRESDRSHSGSSSSLLSAGCFFGEEVRGSGTESAPSDTDASSE XP_004840530.1/1-1166 GVTPSELSGKTWKAIVAARESDHSHSGSSSSLLSAGCFFGDEVKGGS-ESAPSDTDAASE ENSCPOP00000009366/1-1158 GVTPSELSGKTWKAIVAGRESDRSHTGSSSSLLSAGCFFGDEVKGNS-ESAPSDTDTTSE ***************:..**.*:**:**************:**:*.. ********:: * ENSP00000369121/1-1167 VERPGPGQILPAEPLDDSKNATGNSASGLGAGRTAEDTVEDACPAEGSREA----RPNTH ENSMUSP00000082844/1-1166 VERQGPEQPLPKEALDNSTNLKGSLSKGHETSGNTDHSTENACLTEGKEKAPETSRSDEC ENSRNOP00000001347/1-1166 VERQGPERSLPKESLDNSRNLKGSSSKGHESTRNTEDPMENACLAEGQAKAPKTSGPDEC XP_004840530.1/1-1166 AERPRPEQSAPEELSDNSRDPKGSSALSPETGGSAECASVDTCPAEGQGEATQAPGASER ENSCPOP00000009366/1-1158 AERSGPEHSAPQEPLDSSRDHKDNSALGPETEGTAECILENTCPDVEGKEAAQASVTSEH .** * : * * *.* : ... : . : .:: ::* :* .. ENSP00000369121/1-1167 PGPAPTPAELPWTNIDLKEAKKVPSHSAAGFPETTSLSSLGLLPLGLEEPYGVDDHPLWA ENSMUSP00000082844/1-1166 RGPASTPAELPWTNIDLKEPKKVSNQPAAGFPETAGLSSLGLFPMGMEEPYGADDHPLWA ENSRNOP00000001347/1-1166 HGPAPTPAELPWTNIDLKEPKKASNQPAAGFPETSGLSSLGLFPMGMEEPYGADDHPLWA XP_004840530.1/1-1166 PVVASTPAELPWTNIDLKEPRNAPSHSTAGFAETTGLSSLGLCPLGLDEPYGVDEPLLWA ENSCPOP00000009366/1-1158 PNLASAPAELPWTNIDLKEPRKVPSHSAAGFAETVGLSSLGLFPLGLDEPFGADDHPLWA *.:*************.::...:.:***.** .****** *:*::**:*.*: *** ENSP00000369121/1-1167 WVSGGGCVVEACAMPRWFTVQAAGLSSSVHMLSLSITPAQTAAWRKQIFQQLTERTKREL ENSMUSP00000082844/1-1166 WVSGGACAVEAGSTLKWFTIQ-SGLSPSVQTLSLSITPAQTAAWRKQIFQQLTERTKREL ENSRNOP00000001347/1-1166 WVSGGGCAVEAGSALKWFTVQ-SGLSPSVQTLSLSITPAQTAAWRKQIFQQLTERTKREL XP_004840530.1/1-1166 WVSGGSCTVEVGSALKWFTVQ-SGLSPSVQSLSLSITPAQTAAWRKQIFQQLTERTKREL ENSCPOP00000009366/1-1158 WVSGGGCAVEAGSALKWFTVQ-SGLSPSVQTLSLSISPAQTAAWRKQIFQQLTERTKREL *****.*.**. : :***:* :***.**: *****:*********************** ENSP00000369121/1-1167 ENFRHYEQAVEQSVWVKTGALQWWCDWKPHKWVDVRLALEQFTGHDGVRDSILFIYYVVH ENSMUSP00000082844/1-1166 ESFRHYEQAVEQSVWVKTGALQWWCDWKPHKWVDVRVALEQFTGHDGARDSILFIYYVVH ENSRNOP00000001347/1-1166 ESFRHYEQAVEQSVWVKTGALQWWCDWKPHKWVDVRVALEQFTGHDGARDSILFIYYVVH XP_004840530.1/1-1166 ENFRHYEQAVEQSVWVKTGSLQWWCDSKPHKWVDVRVALEQFTGHDGTHDSILFIYYMVH ENSCPOP00000009366/1-1158 ENFRHYEQAVEQSVWVKTGTLQWWCDWKPHKWVDVRVALEQFTGHDGARDSILFVYYIVH *.*****************:****** *********:**********.:*****:**:** ENSP00000369121/1-1167 EEKKYIHIFLNEVVALVPVLNETKHSFALYTPERTRQRWPVRLAAATEQDMNDWLALLSL ENSMUSP00000082844/1-1166 EEKKYLHVFLNEVTVLVPVLNEAKHSFALYTPERTRQRWPVRLAAATEQDMNDWLALLSL ENSRNOP00000001347/1-1166 EEKKYLHVFLNEVTVLVPVLNEAKHSFALYTPERTRQRWPVRLAATTEQDMNDWLTLLSL XP_004840530.1/1-1166 EEKKYFHVFLNEVTALVPVLSEAKHCFALYNPERTRQRWPVRLAAPTEQDMNDWLALLSL ENSCPOP00000009366/1-1158 EEKKYFHVFLNEVTVLVPVLNEAKHSFALYTAERTRQRWPVRLAAATEQDMNDWLALLSL *****:*:*****..*****.*:**.****..*************.*********:**** ENSP00000369121/1-1167 SCCESRKVQGRPSPQAIWSITCKGDIFVSEPSPDLEAHEHPLPCDQMFWRQMGGHLRMVE ENSMUSP00000082844/1-1166 SCCESRKVHGRPSPQAIWSVTCKGDIFVSEPSPDLEARERLLPCDQMFWRQMGGHLRIIE ENSRNOP00000001347/1-1166 SCCESRKVHGRPSLQAIWSVTCKGDIFVSEPSPDLEAHEHLLPCDQMFWRQMGGHLRIIE XP_004840530.1/1-1166 SCCISRKVHGRPSPRAIWSVTCKGDVFVSEPSPDLEAQDRLLPCDQMFWRQMGGHLSMVE ENSCPOP00000009366/1-1158 SCCESRKIHGRPSPQAIWSVTCKGDIFVSEPSSDLEAQDHLLPCDQMFWRQMGGHLRMVE *** ***::**** :****:*****:******.****::: *************** ::* ENSP00000369121/1-1167 ANSRGVVWGIGYDHTAWVYTGGYGGGCFQGLASSTSNIYTQSDVKCVHIYENQRWNPVTG ENSMUSP00000082844/1-1166 ANSRGVVWGIGYDHTAWVYTGGYGGGCFQGLASSTSNIYTQSDVKSVYIYENQRWNPVTG ENSRNOP00000001347/1-1166 ANSRGVVWGIGYDHTAWVYTGGYGGGCFQGLASSTSNIYTQSDVKSVYIYENQRWNPVTG XP_004840530.1/1-1166 ANSRGVVWGIGYDHTAWVYTGGYSGGCVHGLATSNSNIYTQSDVKSICIYENQRWNPVTG ENSCPOP00000009366/1-1158 ANSRGVVWGIGYDHTAWVYTGGYGGGCFQGLASSTSNIYTQSDVKSICIYENQRWNPVTG ***********************.***.:***:*.**********.: ************ ENSP00000369121/1-1167 YTSSRGLPTDRYMWSDASGLQECTKAGTKPPSLQWAWVSDWFVDFSVPGGTDQEGWQYAS ENSMUSP00000082844/1-1166 YT-SRGLPTDRFMWSDVTGLQECTKAGTKPPSLQWTWVSDWYVDFSVPGGTDQEGWQYAS ENSRNOP00000001347/1-1166 YT-SRGLPTDRYMWSDVTGLQECTKAGTKPPSLQWTWVSDWYVDFSVLGGTDQEGWQYAS XP_004840530.1/1-1166 YT-SRGLPTDRYMWSDATGLQECTKASTKPPSLQWTWVSDWYVDFSVPGGTDQEGWQYAS ENSCPOP00000009366/1-1158 YT-SRGLPTDRYMWSDATGLQECTKASTKPPSLQWTWVSDWYVDFSVPGGTDQEGWQYAS ** ********:****.:********.********:*****:***** ************ ENSP00000369121/1-1167 DFPASYHGSKTMKDFVRRRCWARKCKLVTSGPWLEVPPIALRDVSIIPESP---GAEGSG ENSMUSP00000082844/1-1166 DFPASYHGYKTMKDFVRRRCWARKCKLVTSGPWLEVAPITLSDVSIIPESA---HADGRG ENSRNOP00000001347/1-1166 DFPASYHGYKTMKDFVRRRCWARKCKLVTSGPWLEVAPIALSDVSIIPESA---DANGRG XP_004840530.1/1-1166 DFPASYHGYKTMKDFVRRRCWARKCKLVTSGPWLEVAPVALGDVSIIPESPESPEGDGRG ENSCPOP00000009366/1-1158 DFPASYHGYKTMKDFVRRRCWARKCKLVTNGPWLEVAPIALGDVSI--------NGDGRS ******** ********************.******.*::* **** .:* . ENSP00000369121/1-1167 HSIALWAVSDKGDVLCRLGVSELNPAGSSWLHVGTDQPFASISIGACYQVWAVARDGSAF ENSMUSP00000082844/1-1166 HNVALWAVSDKGDVLCRLGVSELNPAGSSWLHVGTDQPFASVSIGACYQVWAVARDGSAF ENSRNOP00000001347/1-1166 HNIALWAVSDKGDVLCRLGVSELNPAGSSWLHVGTDQPFASVSIGACYQVWAVARDGSAF XP_004840530.1/1-1166 RSIALWAVSDKGDILCRLGVSELNPAGSSWLHIGTDQPFASISIGACYQVWAVARDGSAF ENSCPOP00000009366/1-1158 HNIALWAVSDKGDVLCRLGVSELNPVGSSWLHIGTDQPFASVSIGACYQVWAVARDGSAF :.:**********:***********.******:********:****************** ENSP00000369121/1-1167 YRGSVYPSQPAGDCWYHIPSPPRQRLKQVSAGQTSVYALDENGNLWYRQGITPSYPQGSS ENSMUSP00000082844/1-1166 YRGSVSPSQPAGDCWYHIPSPPKQKLTQVSVGQTSVYALDENGNLWYRAGITPSYPQGSS ENSRNOP00000001347/1-1166 YRGSVSPSQPAGDCWYHIPSPPKQKLTQVSVGQTSVYALDENGNLWYRAGITPSYPQGSS XP_004840530.1/1-1166 YRGSVSPSRPAGDCWYHIPSPPKQRLTQVSVGQTSVYALDENGNLWYRGGVTPSYPQGSS ENSCPOP00000009366/1-1158 YRGSVSPSQPAGDCWYHIPSPPKQRLVQVSVGQTSVYALDENGNLWYRAGVTPSYPQGSS ***** **:*************:*:* ***.***************** *:********* ENSP00000369121/1-1167 WEHVSNNVCRVSVGPLDQVWVIANKVQGSHSLSRGTVCHRTGVQPHEPKGHGWDYGIGGG ENSMUSP00000082844/1-1166 WEHVSNNVRKVSVGPLDQVWVIANKVQGSHGLSRGTVCRRMGVQPREPKGQGWDYGIGGG ENSRNOP00000001347/1-1166 WEHVSNNVRKVSVGPLDQVWVIANKVQGSHGLSRGTVCRRMGVQPREPKGQGWDYGIGGG XP_004840530.1/1-1166 WEHVSTNVRRVSVGPLDQVWVIADKVQGTHGLSRGTVCRRTGVQPQEPRGLGWDYGIGGG ENSCPOP00000009366/1-1158 WEHVSNNVRKVSVGPLDQVWVIANKVQGTHGLSRGTVCRRTGVQPREPKGQGWDYGIGGG *****.** :*************:****:*.*******:* ****:**:* ********* ENSP00000369121/1-1167 WDHISVRANATRAPRSSSQEQEPSAPPEAHGPVCC ENSMUSP00000082844/1-1166 WDHISVRANATRVPRNMSRDREARGP----GPVCC ENSRNOP00000001347/1-1166 WDHISVRANATRAPRNMSRDQEAHGP----GPVCC XP_004840530.1/1-1166 WDHISVRANATRASRSVSTEQEAQD------PVCC ENSCPOP00000009366/1-1158 WDHISIRANATRASRNVSQEQKV--P----GPVSC *****:******..*. * ::: **.*