CLUSTAL W(1.81) multiple sequence alignment ENSP00000263071/1-830 -----------MGLGLLLPLLLLWTRGTQGSELD-----PKGQHVCVASSPSAELQCCAG ENSMUSP00000044248/1-820 -------MLAAMGLELVFSLLLLWTQGTQGSTLD-----PAGQHVCKGSSP-SELQCCPG ENSRNOP00000053177/1-823 -------MLTAMGLGLVFSLLLFWTREIQGSTLD-----PAGQHVCIGSSP-SELQCCSG ENSCPOP00000009308/1-798 INPGPPTPLAAMGLELLLPLLLLWTQETQESELD-----PKGQNVCRGSSPLAKLVCCPG XP_004857195.1/1-817 -----------MGLELLLPLLLLWTQKTQESELDPEGLDPEGQNVCKSSSPLAELLCCPG *** *::.***:**: * * ** * **:** .*** ::* **.* ENSP00000263071/1-830 WRQKDQECTIPICEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCP ENSMUSP00000044248/1-820 WRQKDQECTIPICEGPDACRKEEVCVKPGLCRCKPGFFGAQCSSRCPGQYWGHDCRETCP ENSRNOP00000053177/1-823 WRQKDQECTIPICEGPDACKKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRETCP ENSCPOP00000009308/1-798 WKQKDGDCTVPVCEGLDACRKDEVCVKPGFCRCKPGFFGAQCSSSCPDQYWGPDCRETCA XP_004857195.1/1-817 WRQKDQECTIPICEGPDACRKDEVCVKPGLCRCKPGFFGAQCSSPCPDQYWGPDCREICS *:*** :**:*:*** ***:*:*******:**********:*** **.**** **** *. ENSP00000263071/1-830 CHPHGQCEPATGACQCQADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQ ENSMUSP00000044248/1-820 CHPRGQCEPATGDCQCQPNYWGRLCEFPCTCGPHGQCDPKTGLCHCDPGWWSPTCRRPCQ ENSRNOP00000053177/1-823 CHPRGQCEPATGVCQCQPNYWGKLCEFPCTCGPHGKCDPKTGLCHCDPGWWSPTCRRPCQ ENSCPOP00000009308/1-798 CYPHGKCDPATGVCQCHAGRWGDNCESQCSCGPHGHCNPKTGQCRCDPGWWSATCRRQCQ XP_004857195.1/1-817 CHPHGKCDPVTGVCRCQADRWGSNCEFQCSCGTHGRCDPKTGLCHCDPGWWSDTCRRRCR *:*:*:*:*.** *:*:.. ** ** *:**.**:*:* ** *:*:***** **** *: ENSP00000263071/1-830 CNTAAARCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQCE ENSMUSP00000044248/1-820 CN-PASRCDQATGTCVCPPGWWGRRCSFSCNCHTSPCMQDSGRCVCLPGWWGPECSRKCQ ENSRNOP00000053177/1-823 CN-PLARCDQVTGACICPTGWWGHRCSFSCNCHTSPCLQDSGRCTCLQGWWGPECSRRCQ ENSCPOP00000009308/1-798 CN-PAARCDPDTGNCLCPLGMWGRRCNFRCHCHNSPCAPDTGRCMCQAGWLEPDCKR--- XP_004857195.1/1-817 CN-PLAQCDATTGTCLCPSGWWGERCNFRCSCHKSPCTPDTGRCKCLPGWWGTDCRQPCS ** . ::*: ** *:* * **.**.* * ** *** *:*** * ** .:* : ENSP00000263071/1-830 CVRGRCSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESC ENSMUSP00000044248/1-820 CVRGQCSVTSGHCSCPPGFHGIRCELPCNPGHYGAQCKESCGHCELNATCSPVTGNCESC ENSRNOP00000053177/1-823 CVRGQCSVTSGHCSCPPGFQGALCELPCKPGRYGAQCKESCGHCEPNATCSPVTGNCESC ENSCPOP00000009308/1-798 --------------------------PCAPGYYGLQCRQRCGHCKHNAPCSVDTGSCESC XP_004857195.1/1-817 CIYGSCHGTSGQCICKLGFQGTNCDLPCTPGYYGLHCFQRCGHCKQSAPCSKDLGFCESC ** .* :* :* . **:*: . .** * **** ENSP00000263071/1-830 EPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDPCPT ENSMUSP00000044248/1-820 KPGWNGTQCKQPCPAGTFGERCTGQCPRCRLGEPCQAETGHCQHCDPGWLGHRCENPCPL ENSRNOP00000053177/1-823 KPGWNGTQCKQPCPPGTFGERCTGKCPRCRLEEPCQVETGHCQRCDPGWLGHRCEKPCPL ENSCPOP00000009308/1-798 EPGWNGTRCQQPCSPGTFGENCSQQCPHCRDGEPCQIETGDCEHCDPGRLGPRCEDTCPS XP_004857195.1/1-817 EPGWNGTLCQVPCSPGTFGETCSQQCPHCRGGEPCQVETGHCEHCDPGRMGPRCEDSCPV :****** *: ** .***** * :**:** *.*: :**.*::**** :* ***..** ENSP00000263071/1-830 GTFGEDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCECPEGL ENSMUSP00000044248/1-820 GTFGKGCSSTCPACAQGTCDAVTGECVCSAGYWGTSCNSSCPAGFHGNNCSMPCQCPEGL ENSRNOP00000053177/1-823 GTFGKGCSSTCPACVQGTCNAVTGECVCSAGYWGTSCNSSCPSGFHGNNCSMPCQCPEGL ENSCPOP00000009308/1-798 GTFGEGCSSPCPTCVQGACDAVSGECVCSAGYWGTSCNSSCLSGSYGNNCSLPCQCSDGL XP_004857195.1/1-817 GTFGEDCSSICPTCVQGACDPQTGECVCSAGYWGTSCNSSCLPGFYGNNCSLPCQCSDGL ****:.*.* **:*.**:*:. :*:*********.***:** .* :*****:**:*.:** ENSP00000263071/1-830 CHPVSGSCQPGSGSRDTALIAGSLVPLLLLFLGLACCACCCWAPRSDLKDRPARDGATVS ENSMUSP00000044248/1-820 CHPVSGTCQLGRHGKN-ALIVGILVPLLLLLMGIVCCAYCCSGTRLDPKDRPERNGAAFF ENSRNOP00000053177/1-823 CHPESGACQLGPHGKN-ALIVGILVPLLLLLMGIICCVYCCSASRLDPKDRPERNGAAFF ENSCPOP00000009308/1-798 CDPVSGACLWGR--KKSLLIGSILGPLLLLLLGIACCAYCHCATSREPKDRPARGGTALS XP_004857195.1/1-817 CSPVSGACHWGHLSKEVALIAGSLVLLLLLLLGIACY---CWATRLDPKDRPSRGGTTLS * * **:* * :. ** . * ****::*: * .. : **** *.*::. ENSP00000263071/1-830 RMKLQVWGTLTSLGSTLPCRSLSSHKLPWVTVSHHDPEVPFNHSFIEPPSAGWATDDSFS ENSMUSP00000044248/1-820 RMKQQVWGALTNLGSALPCGSLSNYKLPWVTVSHHDPEVPFNHSFIEPPSAGWASDDSFS ENSRNOP00000053177/1-823 RMKQQVWGALTSLGSALPCGSLSNYKLPWVTVSHHDPEVPFNHSFIEPPSAGWASDDSFS ENSCPOP00000009308/1-798 RMKQQFWGALSSLGSVLPCGSLSGYKLPWVTVSHHDPEVPFNHSFIEQPSAGWASEDSFS XP_004857195.1/1-817 RMKQRVCGALSSLGSALLCGSLSGYKLPWVTVSHHDPEVPFNHSFIEQPSAGWASEDSFS *** :. *:*:.***.* * ***.:********************** ******::**** ENSP00000263071/1-830 SDPESGEADEVPAYCVPPQEGMVPVAQAGSSEASLAAGAFPPPEDASTPFAIPRTSSLAR ENSMUSP00000044248/1-820 SDPDSGEEDEAHAYFVPPREEMVPMAQEESPEASLPGGSFPPPEDASTPFPIPRTSSLAR ENSRNOP00000053177/1-823 SDPDSGEEDEAHAYFMPPREETVPMTQEESPAASLPGGPFPPPEDASTPFPIPRTSSLAR ENSCPOP00000009308/1-798 SDSESGAENENSAYCVSSPKGMVPVAPAELSPRESSEATFPPPEDASTPFPIPRTSSLAR XP_004857195.1/1-817 SDSESGAENEDSAYCVSSPKGTVPVAQAESLEA-----TFPPPEDASTPFPIPRTSSLAR **.:** :* ** :.. : **:: .***********.********* ENSP00000263071/1-830 AKRPSVSFAEGTKFAPQSRRSSGELSSPLRKPKRLSRGAQSGPEGREAEESTGPEEAEAP ENSMUSP00000044248/1-820 AKRPSVSFAEGTKFAPQNGRSSGDLSSPIRKPKRLSRGAQPRPEGQEAEESTGPEQVNTE ENSRNOP00000053177/1-823 AKRPSVSFAEGTKFAPQNGRSSGDLSSPIRKPKRLSRGAQPRPEGQEAEESTGPEQENPE ENSCPOP00000009308/1-798 AKRPSVSFAEGTKFVSQSGRSSGELHSPARKPKRLSRGAQPGPEGRETEESTSLEQAKMD XP_004857195.1/1-817 AKRPSVSFAEGTKFVSQSCRSSGELSSPIRKPKRLSRGAQAGPESQETEESTSMEQAQVD **************..*. ****:* ** ***********. **.:*:****. *: : ENSP00000263071/1-830 ESFPAAASPGDSATGHRRPPLGGRTVAEHVEAIEGSVQESSGPVTTIYMLAGKPRGSEGP ENSMUSP00000044248/1-820 EDAPTATSSGDPATSHGQLPPGSQMVAECAETTDGGIQESSGSVATIYMLAGTPQKPEGP ENSRNOP00000053177/1-823 EDVPTATSSGDAATSHGQLPPGSRTVTECVETTDGGIQESSGSVATIYMLAGTPQKPEGP ENSCPOP00000009308/1-798 KAPTAAARSGNSANGH-QAPCGSQKVAKPGETTEGSMQESSDSAASIYMLVGMPEKSKGP XP_004857195.1/1-817 KAPPAAARPSNSANGH-RFPLDNQRVAEHGETTKDNVQKSSDSVATIYMLAGMPERSEGP : .:*: ..:.*..* : * ..: *:: *: ...:*:**...::****.* *. .:** ENSP00000263071/1-830 VRSVFRHFGSFQKGQAEAKVKRAIPKPPRQALNRKKGSPGLASGSVGQSPNSAPKAGLPG ENSMUSP00000044248/1-820 VWSVFRRLGNYQKDQMDPKVKSAIPKPLRRSLGRNQAS-----------AGSAPGAVLSQ ENSRNOP00000053177/1-823 VWSVFRRLGNYQKDQAAPKVKSAIPKPLRRSLGRNQASSGLS-----QSSGSAPGAVLSG ENSCPOP00000009308/1-798 VRSVLRRLGNFQKGQEEPKVKSAIPKPPRRALGQKKGS---------QSPGLAPSANAAG XP_004857195.1/1-817 VWSVFRRLGNFQKGQAEAKVKSAIPKPPRRALAQ-KGSTTPSPGSANQSPGLAPS--LVG * **:*::*.:**.* .*** ***** *::* : :.* .. ** ENSP00000263071/1-830 ATGPMAVRPEEAVRGLGAGTESSRRAQEPVSGCGSPEQDPQKQAEEERQEEPEYENVVPI ENSMUSP00000044248/1-820 AMESTAVRPEETPRGLGDGIESSGTVQEPDAGGSSLEQDSQKQAEEKEQEEPLYENVVPM ENSRNOP00000053177/1-823 AMESTAVKPEEASRGLGDGIESLGTVQEPVVGSSSPEQGSQKQAEEQEQEEPLYENVVPM ENSCPOP00000009308/1-798 AVEPVGVKPEEVSRGLGDGRESPGRPQEPISSSSLPEQDPQKHVEEEEQEEPLYEN-VHT XP_004857195.1/1-817 AAESRGVRQEEVSRVLGDGSENPGGTWEPVSRNSLPEHAPQKQAEEEGAEEPLYEN-VRV * . .*: **. * ** * *. ** . *: .**:.**: *** *** * ENSP00000263071/1-830 SRPPEP ENSMUSP00000044248/1-820 SVPPQH ENSRNOP00000053177/1-823 LQH--- ENSCPOP00000009308/1-798 SGWPES XP_004857195.1/1-817 PG----