CLUSTAL W(1.81) multiple sequence alignment ENSMUSP00000040568/1-926 ------------------------------------------------------------ ENSRNOP00000027032/1-926 ------------------------------------------------------------ ENSP00000386125/1-1030 MVTLGAGVRLFTGVYPVVLNQIRATSEASAITRTTMPAPELTSTSRAEDTRDTGVQLRKR ENSCPOP00000009244/1-936 ------------------------------------------------------------ XP_004856306.1/1-942 ------------------------------------------------------------ ENSMUSP00000040568/1-926 -----------------------------------MAAARPALTDSLSFCLAQLTAAAGE ENSRNOP00000027032/1-926 -----------------------------------MAAARPALTDSLSFCLAQLTAAAGE ENSP00000386125/1-1030 KIPQARHSRKRQRTFSFRSLGSAARSGAESEARAKMAAAKPTLTDSLSFCLAQLAAAAGE ENSCPOP00000009244/1-936 -----------------------------------MAAAKATLTDSLSFCLAQLTAAAGE XP_004856306.1/1-942 -----------------------------------MAATRATLTDSLSFCLAQLTAAAGE ***::.:************:***** ENSMUSP00000040568/1-926 GPGGGKDPATNETPLGRALLALRTRHIKAAEGIERFRARGGLRPLLALLRRTAAAGPAPS ENSRNOP00000027032/1-926 GPGGGKDPATNETALGRVLLALRTRHIKAAEGIERFRARGGLRPLVALLRRTAAAGPAPS ENSP00000386125/1-1030 ALGGEKDPATNETPLSRALLALRTRHIKAAGGIERFRARGGLRPLLALLRRAAAAGSAPS ENSCPOP00000009244/1-936 GLYGGKDPATNETPLGRALLALRTRHIKAAGGIERFRARGGLRPLLALLRRAAAADPAPS XP_004856306.1/1-942 GLAGGKDPAINETPLGRALLALRTRHIKAAGGIERFRARDGLRPLLALLRR-AAADPAPS . * **** ***.*.*.************ ********.*****:***** ***..*** ENSMUSP00000040568/1-926 QAASGSAPSSVASAGST-----PGHAPAAESLLTPSLPMRLRKTLDLALSILANCCTEGA ENSRNOP00000027032/1-926 QAASGSAPPSVASAGSS-----PGPAPAAESPLTLSAPMRLRKTLDLALSILANCCTEGA ENSP00000386125/1-1030 QAGPGSAPSSAASGASS-PAPASGPAPSAVSSSSPTPPVRLRKTLDLALSILADCCTEGA ENSCPOP00000009244/1-936 PAGPGSAPLSVASAASAGPSPSPNPASSAVSPSSPSPPMRLRKTLDLALSILANCCTEGA XP_004856306.1/1-942 HAGPGSAPLSVASAASAGPSPSPSP-PSSVSLSTSSPPVRLRKTLDLALSILANCCTEGA *..**** *.**..*: .. .:: * : : *:**************:****** ENSMUSP00000040568/1-926 CRAEVRRLGGILPLVTILQCVKTDSIQNRTARALGNLAMEPESCRDIHS-AGAVPFLVES ENSRNOP00000027032/1-926 CRSEVRRIGGILPLVTILQCVRIDSIQNRTARALGNLAMEPESCGDIHS-AGAVPFLVES ENSP00000386125/1-1030 CRTEVRRLGGILPLVTILQCMKTDSIQNRTARALGNLAMEPESCGDIHC-AGAVPLLVES ENSCPOP00000009244/1-936 CRAEVRRLGGILPLVTILQCVKTDSIQNRTARALGNLAMEPESCGEIHSAAGAVPLLVES XP_004856306.1/1-942 CRAEVRRLGGILPLVTILQCVKTDSIQNRTARALGNLAVEPESCGEIHS-AGAVPLLVES **:****:************:: ***************:***** :**. *****:**** ENSMUSP00000040568/1-926 LTACQDSQCLQSIVRALRNLADSPQHRLALAQQGAVRPLAELLATAPDPALTAALVRALL ENSRNOP00000027032/1-926 LTACQDSQCLQSIVRALRNLADSPQHRLALAQQGAVRPLAELLATAPDPALTSALVRALL ENSP00000386125/1-1030 LTACQDSQCLQSVVRALRNLADSPQHRLALAQQGAVRPLAELLATAPDAALTLALVRALL ENSCPOP00000009244/1-936 LTACQDSQCLQSVVRALRNLADSPQHRLALAQQGAVRPLAELLAAAPDPALTSALVRALL XP_004856306.1/1-942 LTACQDSQCLQSVVRALRNLADSPQHRLALAQQGAVRPLAELLAAAPDPALTSALVRALL ************:*******************************:***.*** ******* ENSMUSP00000040568/1-926 ELSRGCSRACAEQLSLGGALGPLVSLASHPKRAIREAAILILANLCAQGLVRPALGNAGG ENSRNOP00000027032/1-926 ELSRGCSRACAEQLSLGGGLGPLVSLASHPKRAIREAAILILANLCAQGLVRPALGNAGG ENSP00000386125/1-1030 ELSRGCSRACAEQLSLGGGLGPLVSLASHPKRAVREGTILILANLCAQGLIRPALGNAGG ENSCPOP00000009244/1-936 ELSRGCTRACAEQLSLGGGLGPLVSLASHPKRMVRETTILILANLCAQGLVRPALGNAGG XP_004856306.1/1-942 ELSRGCSRACAEQLSLGGGLGPLVSLASHPKRMVREATILILANLCAQGLVRPALGNAGG ******:***********.************* :** :************:********* ENSMUSP00000040568/1-926 VEVLLGELRRRRSPGGSSSATQQPLVRAVCLLCREAINRARLRDAGGLELLMGLLQDPGA ENSRNOP00000027032/1-926 VEVLLGELRRRRGPSGSSSASQQPLVRAVCLLCREAINRARLRDAGGLELLMGLLQDPGA ENSP00000386125/1-1030 VEVLVDELRQRRDPNGASPTSQQPLVRAVCLLCREAINRARLRDAGGLDLLMGLLRDPRA ENSCPOP00000009244/1-936 VEVLLGELRRRRGPSGASPASQQPLVRAVCLLCREAINRARLRDAGGLELLMGLLRDPRA XP_004856306.1/1-942 VEVLLGELRRRRGPSGASPASQQPLVRAVCLLCREAINRARLRDAGGLEVLMGLLRDPHA ****:.***:**.*.*:*.::***************************::*****:** * ENSMUSP00000040568/1-926 SAWHPRVVAALVGFLYDTGALGKLQALGLVPLLARQLCGEAGEEEEEGIEAASWDFPEER ENSRNOP00000027032/1-926 SAWHPRVVAALVGFLYDTGALGKLQALGLVPLLARQLCGEAGEEEEEGVEAASWDFPEER ENSP00000386125/1-1030 SAWHPRIVAALVGFLYDTGALGRLQALGLVPLLAGQLCGEAGEEEEEGREAASWDFPEER ENSCPOP00000009244/1-936 SAWHPRVVAALVGFLYDTGALGRLQALGLVPLLAGQLCGDAGEEEEEGREAASWDFPEER XP_004856306.1/1-942 SAWHPRVVAALVGFLYDTGALGRLQALGLVPLLAGQLCDNTGEEEEEGREAASWDFPEER ******:***************:*********** ***.::******* *********** ENSMUSP00000040568/1-926 TSGQAEGGSFRSLRLWLISEGYAAGPGDISPDWSPERCPMPEPSESVSPTPGQTSMSTPR ENSRNOP00000027032/1-926 TSGQPEGGSFRSLRLWLISEGYAAGPGDISPDWSPERCPMPEPSESVSPTPGQTSMSTPR ENSP00000386125/1-1030 TPERAQGGSFRSLRSWLISEGYATGPDDISPDWSPEQCP-PEPMEPASPAPTPTSLRAPR ENSCPOP00000009244/1-936 TPERAEAGSFRSLRSWLISEGYA---GDVSPDWSPEHCPLPEPTDPISSTPGKTSLRTPG XP_004856306.1/1-942 TPERAEAGSFRSLRSWLISEGYAVGPGDVSPDWSPEHFPLPEPADSISNTPGKTSLRTPC *. :.:.******* ******** .*:*******: * *** :. * :* **: :* ENSMUSP00000040568/1-926 TLRKPGRIP----AATPEEPWGQEGPALLLLSRFSQAPDPSGALVTGPALCGLLAYVTGA ENSRNOP00000027032/1-926 TLRKLGRVP----AATTEEPWGQEGPALLLLSRFSQAPDPSGALVTGPALCGLLAYVTGA ENSP00000386125/1-1030 TQRTPGRSP----AAAIEEPWGREGPALLLLSRFSQAPDPSGALVTGPALYGLLTYVTGA ENSCPOP00000009244/1-936 IPRTLGRSP--AGPSALEEPWGREGPALLLLSRFSQAPDPSGALVTGPALCGLLAYVTGA XP_004856306.1/1-942 TLHTLGYSPTAAAATAAEEPWGREGPALLLLSRFSQAPDPSGALVTGPALCGLLAYVTGA :. * * .:: *****:*************************** ***:***** ENSMUSP00000040568/1-926 PGPPNPRALRILARLTCNPACLEAFVRTYGAALLRAWLVLGVSPDDWPVPHARPVHRSQH ENSRNOP00000027032/1-926 PGPPNPRALRILARLTCNPACLEAFVRSYGAALLRAWLVLGVSPDDWPVPHARPVHRSQH ENSP00000386125/1-1030 PGPPSPRALRILSRLTCNPACLEAFVRSYGAALLRAWLVLGVAPDDWPAPRARPTLHSRH ENSCPOP00000009244/1-936 PGPPNPRALRILARLTCNPACLEAFVRSYGAALLRAWLVLGVAPDDWPAPRTRPVRRNQH XP_004856306.1/1-942 PGPPSPRALRILARLTCNPACLEAFVRSYGAALLRAWLVLGVAPDDWPAPRPRPVCRNQH ****.*******:**************:**************:*****.*:.**. :.:* ENSMUSP00000040568/1-926 RELGEMLLQNLTVQAESPFGVGALTHLLLSGSPEDRVACALTLPFIC-RKPTLWRRLLLD ENSRNOP00000027032/1-926 RELGEMLLQNLTVQAESPFGVGALTHLLLSGSPEDRVACALTVPFIC-RKPTLWRRLLLD ENSP00000386125/1-1030 RELGERLLQNLTVQAESPFGVGALTHLLLSGSPEDRVACALTLPFIC-RKPSLWRRLLLE ENSCPOP00000009244/1-936 RELGEMLLQNLTVQAESPFGVGALTHLLLSGSSEDRVACALTLPFICRRKPSLWRRLLLD XP_004856306.1/1-942 RELGEMLLQNLTVQAESPFGVGALTHLLLSGSSEDRVACALTLPFIC-RKPSLWRRLLLD ***** **************************.*********:**** ***:*******: ENSMUSP00000040568/1-926 QGGLRLLLTALTQPAPHPLFLFFAADSLSCLQGLVSPTASPVPLPALPLELDSPPPCLYE ENSRNOP00000027032/1-926 QGGLRLLLTALTQPAPHPLFLFFAADSLSCLQGLVSPSASPVPLPDLPLELDSPSPCLYK ENSP00000386125/1-1030 QGGLRLLLAALTRPAPHPLFLFFAADSLSCLQDLVSPTVSPAVPQAVPMDLDSPSPCLYE ENSCPOP00000009244/1-936 QGGLRLLLTALTRPAPHPLFLFFAADSLFCLQGLVSPTMSPAFPAAVPVDVEPPSPCLYE XP_004856306.1/1-942 QGGLRLLLTALTRPAPHPLFLFFAADSLFCLQGLVSPVMSPAFPPETPVELDPPSPCLYE ********:***:*************** ***.**** **. *::::.*.****: ENSMUSP00000040568/1-926 PLLGPAPAPAPDLHFVLDSGLQLPAQRAASAAASPFFRALLSGSFAEAQMDLVPLRGLSP ENSRNOP00000027032/1-926 PLLGPAPAPAPDLHFVLDSGLQLPAQRAASAAASPFFRALLSGSFAEAQMNLVPLRGLSP ENSP00000386125/1-1030 PLLGPAPVPAPDLHFLLDSGLQLPAQRAASATASPFFRALLSGSFAEAQMDLVPLRGLSP ENSCPOP00000009244/1-936 PLLGPAPVPAPDLYFLLDSGLQLP-QRAVSATASPFFRALLSGSFAEAHMDLVPLRGLSP XP_004856306.1/1-942 PLLGPAPVPAPDLYFLLDSGLQLPAQRAASATASPFFRALLSGSFAEAKMDLVPLRGLSP *******.*****:*:******** ***.**:****************:*:********* ENSMUSP00000040568/1-926 GAAWPVLHHLHGCRGCGAALGPVPPPGQPLLGSKAEEALEAAGRFLLPALEEELEEAVGR ENSRNOP00000027032/1-926 SAAWPVLHHLHGCRGCGAALGPIPPPGQPLLGSKAEEALEAAGRFLLPALEEELEEAVGR ENSP00000386125/1-1030 GAAWPVLHHLHGCRGCGAALGPVPPPGQPLLGSEAEEALEAAGRFLLPGLEEELEEAVGR ENSCPOP00000009244/1-936 SAAWPILHHLHGCRGCGAALGPIPLAGQPLLGSEAEEALEAAGRFLLPSLEEELEEAVGR XP_004856306.1/1-942 SAAWPVLHHLHGCRGCGAALGPVPAPGQPLLGSDAEEALEAAARFLLPGLEEELEEAVGR .****:****************:* .*******.********.*****.*********** ENSMUSP00000040568/1-926 IHLSPRGGPESVGEVFRLGRPRLAAHCARWTLEPGQCPRKRALALTGLVEAAGEEAGPLT ENSRNOP00000027032/1-926 IHLSPQGGPESVGEVFRLGRPRLAAHCARWTLEPGQCPRKRALALTGLVEAAGEEAGPLT ENSP00000386125/1-1030 IHLGPQGGPESVGEVFRLGRPRLAAHCARWTLGSEQCPRKRGLALVGLVEAAGEEAGPLT ENSCPOP00000009244/1-936 IHLGPEGSPESVGEVFRLGRPRLTAYCARWTLGPARCP-KRALALAGLVEAAGEEAGPLT XP_004856306.1/1-942 IHLGAEGAPESVVEVFRLGRPRLAALCARWTLGPGQCPRKRALALVGLVEAAGEEAGPLT ***...*.**** **********:* ****** . :** **.***.************** ENSMUSP00000040568/1-926 EALLAVVMGIES--------- ENSRNOP00000027032/1-926 EALLAVVMGVES--------- ENSP00000386125/1-1030 EALLAVVMGIELGARVPA--- ENSCPOP00000009244/1-936 EALLSVVMGIESGGKSPS--- XP_004856306.1/1-942 EALLAVVMGIESRDKGPSLDG ****:****:*