CLUSTAL W(1.81) multiple sequence alignment ENSCPOP00000008917/1-1115 ------------------------------------------------------------ XP_004921118.1/1-1360 MPSSADPALGGGAGLSWAEKKLEERRKRRRFLSPQQPPLLLPLLQPQLLQPPPPPPPLLF ENSP00000181839/1-1512 MPSSSDTALGGGGGLSWAEKKLEERRKRRRFLSPQQPPLLLPLLQPQLLQPPPPPPPLLF ENSMUSP00000036013/1-1511 MPSSSDTALGGGGGLSWAEKKLEERRKRRRFLSPQQPPLLLPLLQPQLLQPPPPPPPLLF ENSRNOP00000018431/1-1508 MPSSSDTALGGGGGLSWAEKKLEERRKRRRFLSPQQPPLLLPLLQPQLLQPPPPPPPLLF ENSCPOP00000008917/1-1115 ------------------------------------------------------------ XP_004921118.1/1-1360 LAAPGTAAAAAAAAAAASA----------------------------------------- ENSP00000181839/1-1512 LAAPGTAAAAAAAAAASSSCFSPGPPLEVKRLARGKRRAGGRQKRRRGPRAGQEAEKRRV ENSMUSP00000036013/1-1511 LAAPGAAAAAAAAAAASSSCFSPGPPLEVKRLARGKRRPGGRQKRRRGPRAGQEAEKRRV ENSRNOP00000018431/1-1508 LAAPGAAAAAAAAAAASSSCFSPGPPLEVKRLARGKRRPGGRQKRRRGPRAGQEAEKRRV ENSCPOP00000008917/1-1115 ------------------------------------------------------------ XP_004921118.1/1-1360 ------------------------------------------------------------ ENSP00000181839/1-1512 FSLPQPQQDGGGGASSGGGVTPLVEYEDVSSQSEQGLLLGGASAATAATAAGGTGGSGGS ENSMUSP00000036013/1-1511 FSLPQPQQDGGGGASSGGGVTPLVEYEDVSSQSEQGLLLGGASAATAATAAGGTGGNGGS ENSRNOP00000018431/1-1508 FSLPQPQQDGGGGASSGGGVTPLVEYEDVSSQSEQGLLLGGASAATAATAAGGTGGNGGS ENSCPOP00000008917/1-1115 ------------------------------------------------------------ XP_004921118.1/1-1360 ---------------------------------------------SCASKGRGRHG---- ENSP00000181839/1-1512 PASSSGTQRRGEGSERRPRRDRRSSSGRSKERHREHRRRDGQRGGSEASKSRSRHSHSGE ENSMUSP00000036013/1-1511 PASSSGTQRRAEGSERRPRRDRRSSSGRSKERHREHRRRDGTRSGSEASKARSRHGHSGE ENSRNOP00000018431/1-1508 PASSSGTQRRAEGXQRRPRRDRRSSSGRSKERHREHRRRDGTRSGSEASKARSRHGHSGE ENSCPOP00000008917/1-1115 ------------------------------------------------------------ XP_004921118.1/1-1360 DRAEPAESGSRSSSRGRRRKSASATSSSGGRKERDSKVRRGRSRAGKEPPSAYREPPKAY ENSP00000181839/1-1512 ERAEVAKSGSSSSSGGRRKSASATSSSSSSRKDRDSKAHRSRTKSSKEPPSAYKEPPKAY ENSMUSP00000036013/1-1511 ERAEAAKSGSSSSSGGRRKSASATSSSSSSRKDRDLKAHRSRTKSSKEPPSAYKEPPKAY ENSRNOP00000018431/1-1508 ERAEAAKSGSSSSSGGRRKSASATSSSSSSRKDRDLKAHRSRTKSSKEPPSAYKEPPKAY ENSCPOP00000008917/1-1115 ------------------------------------------------------------ XP_004921118.1/1-1360 RDDKAEPRAYRRRPRSPSP-PGRDDSPGSHRAAPGPRSRRSPSPAGG--SPYTRR-PRSP ENSP00000181839/1-1512 REDKTEPKAYRRR-RSLSPLGGRDDSPVSHRASQSLRSRKSPSPAGGGSSPYSRRLPRSP ENSMUSP00000036013/1-1511 REDKSEPKAYRRRQRSLSPLGGRDESPVSHRASQSLRSRKSPSPAGGGSSPYSRRLPRSP ENSRNOP00000018431/1-1508 REDKSEPKAYRRRQRSLSPLGGRDESPVSHRASQSLRSRKSPSPAGGGSSPYSRRLPRSP ENSCPOP00000008917/1-1115 -------------------------------------SPYSPVLRRSAKSRSRSPYSSRH XP_004921118.1/1-1360 SPY-RRRSRSYSRASSYERGGDVSPSPYSGGSWRRSRSPYSPVLRRSAKSRSRSPYSSRH ENSP00000181839/1-1512 SPYSRRRSPSYSRHSSYERGGDVSPSPYSSSSWRRSRSPYSPVLRRSGKSRSRSPYSSRH ENSMUSP00000036013/1-1511 SPYSRRRSPSYSRHSSYERGGDVSPSPYSSSSWRRSRSPYSPVLRRSAKSRSRSPYSSRH ENSRNOP00000018431/1-1508 SPYSRRRSPSYSRHSSYERGGDVSPSPYSSSSWRRSRSPYSPVLRKKKKAMELKPFNNYY ********:. *: . .*:.. : ENSCPOP00000008917/1-1115 SRSRSRHRLSRSRSRHSSISPSTLTLKSSLAAELNKNKKARAAEAARAAEAAKAAEAAKA XP_004921118.1/1-1360 SRSRSRHRLSRSRSRHSSISPSTLTLKSSLAAELNKNKKARAAEAARAAEAAKAAEAAKA ENSP00000181839/1-1512 SRSRSRHRLSRSRSRHSSISPSTLTLKSSLAAELNKNKKARAAEAARAAEAAKAAEATKA ENSMUSP00000036013/1-1511 SRSRSRHRLSRSRSRHSSISPSTLTLKSSLAAELNKNKKARAAEAARAAEAAKAAEAAKA ENSRNOP00000018431/1-1508 TRPSSLHILSRFVFRHVLLTPEWLTLCQSLVKELS---FPRAAEAARAAEAAKAAEAAKA :*. * * *** ** ::*. *** .**. **. .*****************:** ENSCPOP00000008917/1-1115 AEAAAKAAKASNTSTPTKVNTETGASSSQTNHVKDVKKVKTELAPSPSSGGTLKNDKAKT XP_004921118.1/1-1360 AEAAAKAAKASNTSTPTKGNTETGASSSQTNHVKDVKKLKTEHAPSPSSGGTLKNDKAKS ENSP00000181839/1-1512 AEAAAKAAKASNTSTPTKGNTETSASASQTNHVKDVKKIKIEHAPSPSSGGTLKNDKAKT ENSMUSP00000036013/1-1511 AEAAAKAAKASNASTPTKGNTETGASVSQTNHVKEVKKLKTEHAPSPSSGGTVKSDKAKT ENSRNOP00000018431/1-1508 AEAAAKAAKASSVSTPTKGNTETGASVSQTNHVKEVKKLKTEHAPSPSSGGTVKSDKTKT ***********..***** ****.** *******:***:* * *********:*.**:*: ENSCPOP00000008917/1-1115 KPPLQVTKVDNNLVLDKTTKKTAVVGKESKSAATKEEPVSLKEKTKPLTPSIGAKEKEQH XP_004921118.1/1-1360 KPPLQVTKVDNNLIVDKATKKTAVIGKESKSAATKEEPVSLKEKTKPLTPSVGAKEKEQH ENSP00000181839/1-1512 KPPLQVTKVENNLIVDKATKKAVIVGKESKSAATKEESVSLKEKTKPLTPSIGAKEKEQH ENSMUSP00000036013/1-1511 KPPLQVTKVDNNLTVEKATKKT-VVGKESKPAATKEEPVSTKEKSKPLTPSTGAKEKEQH ENSRNOP00000018431/1-1508 KPPLQVTKVDNNLIVEKATKKT-VVGKESKPAATKEEPVSTKEKTKPLTPSVGAKEKEQH *********:*** ::*:***: ::*****.******.** ***:****** ******** ENSCPOP00000008917/1-1115 VTLVTSTLPPLPLPPMLPEDKDADSLRGNISVKAVKKEVEKKLRCLLADLPLPPELP--G XP_004921118.1/1-1360 VTLVTSTLPPLPLPPMLPEDKDTDSLRGSISVKAVKKEVEKKXRCLLADLALPSHLPPKG ENSP00000181839/1-1512 VALVTSTLPPLPLPPMLPEDKEADSLRGNISVKAVKKEVEKKLRCLLADLPLPPELP--G ENSMUSP00000036013/1-1511 VALVTSTLPPLPLPPMLPEDKDADSLRGNISVKAVKKEVEKKLRCLLADLPLPPELP--G ENSRNOP00000018431/1-1508 VALVTSTLPPLPLPPMLPEDKDADSLRGNISVKAVKKEVEKKLRCLLADLPLPPELP--G *:*******************::*****.************* *******.**..** * ENSCPOP00000008917/1-1115 GDDLSKSPEEKKTTTQLHSKRRPKICGPRYGEIKEKDIDWGKRCVDKFDIIGIIGEGTYG XP_004921118.1/1-1360 GEDLSKSPEEKKTATQLHSKRRPKICGPRYGEIKEKDIDWGKRCVDKFDIIGIIGEGTYG ENSP00000181839/1-1512 GDDLSKSPEEKKTATQLHSKRRPKICGPRYGETKEKDIDWGKRCVDKFDIIGIIGEGTYG ENSMUSP00000036013/1-1511 GDDLSKSPEEKKTAAQLHSKRRPKICGPRYGEIKEKDIDWGKRCVDKFDIIGIIGEGTYG ENSRNOP00000018431/1-1508 GDDLSKSPEEKKTATQLHSKRRPKICGPRYGEIKEKDIDWGKRCVDKFDIIGIIGEGTYG *:***********::***************** *************************** ENSCPOP00000008917/1-1115 QVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTHQSIINMKEIVTDKEDA XP_004921118.1/1-1360 QVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTHQSIINMKEIVTDKEDA ENSP00000181839/1-1512 QVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTHQSIINMKEIVTDKEDA ENSMUSP00000036013/1-1511 QVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTHQSIINMKEIVTDKEDA ENSRNOP00000018431/1-1508 QVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTHQSIINMKEIVTDKEDA ************************************************************ ENSCPOP00000008917/1-1115 LDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQLMEGLDYCHKKNFLHRD XP_004921118.1/1-1360 LNFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQLMEGLDYCHKKNFLHRD ENSP00000181839/1-1512 LDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQLMEGLDYCHKKNFLHRD ENSMUSP00000036013/1-1511 LDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQLMEGLDYCHKKNFLHRD ENSRNOP00000018431/1-1508 LDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQLMEGLDYCHKKNFLHRD *:********************************************************** ENSCPOP00000008917/1-1115 IKCSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYRPPELLLGEERYTPAIDV XP_004921118.1/1-1360 IKCSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYRPPELLLGEERYTPAIDV ENSP00000181839/1-1512 IKCSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYRPPELLLGEERYTPAIDV ENSMUSP00000036013/1-1511 IKCSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYRPPELLLGEERYTPAIDV ENSRNOP00000018431/1-1508 IKCSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYRPPELLLGEERYTPAIDV ************************************************************ ENSCPOP00000008917/1-1115 WSCGCILGELFTKKPIFQANQELAQLELISRICGSPCPAVWPDVIKLPYFNTMKPKKQYR XP_004921118.1/1-1360 WSCGCILGELFTKKPIFQANQELAQLELISRICGSPCPAVWPDVIKLPYFNTMKPKKQYR ENSP00000181839/1-1512 WSCGCILGELFTKKPIFQANQELAQLELISRICGSPCPAVWPDVIKLPYFNTMKPKKQYR ENSMUSP00000036013/1-1511 WSCGCILGELFTKKPIFQANQELAQLELISRICGSPCPAVWPDVIKLPYFNTMKPKKQYR ENSRNOP00000018431/1-1508 WSCGCILGELFTKKPIFQANQELAQLELISRICGSPCPAVWPDVIKLPYFNTMKPKKQYR ************************************************************ ENSCPOP00000008917/1-1115 RKLREEFVFIPAAALDLFDYMLALDPSKRCTAEQALQCEFLRDVEPSKMPPPDLPLWQDC XP_004921118.1/1-1360 RKLREEFVFIPAAALDLFDYMLALDPSKRCTAEQALQCEFLRDVEPSKMPPPDLPLWQDC ENSP00000181839/1-1512 RKLREEFVFIPAAALDLFDYMLALDPSKRCTAEQALQCEFLRDVEPSKMPPPDLPLWQDC ENSMUSP00000036013/1-1511 RKLREEFVFIPAAALDLFDYMLALDPSKRCTAEQALQCEFLRDVEPSKMPPPDLPLWQDC ENSRNOP00000018431/1-1508 RKLREEFVFIPAAALDLFDYMLALDPSKRCTAEQALQCEFLRDVEPSKMPPPDLPLWQDC ************************************************************ ENSCPOP00000008917/1-1115 HELWSKKRRRQKQMGMTDDVSTIKAPRKELSLGLDDSRTNTPQGVLPTTQLKSQGNSNVA XP_004921118.1/1-1360 HELWSKKRRRQKQMGMTDDVSTIKAPRKDLSLGLDDSRTNTPQGVLPATQLKSQGNSNVA ENSP00000181839/1-1512 HELWSKKRRRQKQMGMTDDVSTIKAPRKDLSLGLDDSRTNTPQGVLPSSQLKSQGSSNVA ENSMUSP00000036013/1-1511 HELWSKKRRRQKQMGMTDDLSTIKAPRKDLSLGLDDSRTNTPQGVLPPAQLKSQSNSNVA ENSRNOP00000018431/1-1508 HELWSKKRRRQKQMGMTDDLSTIKAPRKDLSLGLDDSRTSTPQGVLPPAQLKSQNSSSGA *******************:********:**********.*******.:*****..*. * ENSCPOP00000008917/1-1115 PVITGSGQQLNHSELAILLNLLQSKTSINMADFVQVLNIKVNSETQQQLNKITFLLN-FG XP_004921118.1/1-1360 PVITGPGQQLNHSELAILLNLLQSKTSINMADFVQVLNIKVNSETQQQLNKINLPAGILA ENSP00000181839/1-1512 PVKTGPGQHLNHSELAILLNLLQSKTSVNMADFVQVLNIKVNSETQQQLNKINLPAGILA ENSMUSP00000036013/1-1511 PVITGPGQPLNHSELAILLNLLQSKSSVNMADFVQVLNIKVNSETQQQLNKINLPAGILA ENSRNOP00000018431/1-1508 PVITGPGQPLNHSELAILLNLLQSKSSVNMADFVQVLNIKVNSETQQQLNKINLPAGILA ** **.** ****************:*:************************.: . :. ENSCPOP00000008917/1-1115 TGEKQTDPSTPQQESSKPLGGIQPSSQTVPPKVETDAAQAAVQSAFAVLLTQLIKAQQSK XP_004921118.1/1-1360 TGEKQTDPSTPQQESSKPLGGIQPSSQTVQPKVETDAAQAAVQSAFAVLLTQLIKAQQSK ENSP00000181839/1-1512 TGEKQTDPSTPQQESSKPLGGIQPSSQTIQPKVETDAAQAAVQSAFAVLLTQLIKAQQSK ENSMUSP00000036013/1-1511 TGEKQTDPSTPQQESSKSLGGVQP-SQTIQPKVETDAAQAAVQSAFAVLLTQLIKAQQSK ENSRNOP00000018431/1-1508 TGEKQTDPSTPQQESSKSLGGVQP-SQSIQPKVETDAAQAAVQSAFAVLLTQLIKAQQSK *****************.***:** **:: ****************************** ENSCPOP00000008917/1-1115 QKDVLLEERENGSGHDASLQLRPPPEPSTPVSGQDDLIQQQDRRRLELTPEPDRPRILPP XP_004921118.1/1-1360 QKDVLLEERENGSGHDASLQLRPPPEPGTPVSGQDDLIQHQDRRRLELTPEPERPRILPP ENSP00000181839/1-1512 QKDVLLEERENGSGHEASLQLRPPPEPSTPVSGQDDLIQHQDMRILELTPEPDRPRILPP ENSMUSP00000036013/1-1511 QKDAMLEERENGSGHEAPLQLRPPLEPSTPGSGQDDLIQHQDRRILELTPEPDRPRILPP ENSRNOP00000018431/1-1508 QKDAMLEERENGSGHDAPVQLRPPPEPSTPASGQDDLIQHQDRRILELTPEPERPRILPP ***.:**********:*.:***** **.** ********:** * *******:******* ENSCPOP00000008917/1-1115 DQRPPEPPEPPPVTEEDLDYRTENQHVSTTSSSLTDPHAGVKAALLQLLAQHQPQDEPKR XP_004921118.1/1-1360 DQRPPEPPEPPPVTEEDLDYRTENQHVPTTSSSLTDPHAGVKAALLQLLAQHQPQEEPKR ENSP00000181839/1-1512 DQRPPEPPEPPPVTEEDLDYRTENQHVPTTSSSLTDPHAGVKAALLQLLAQHQPQDDPKR ENSMUSP00000036013/1-1511 DQRPPEPPEPPPVTEEDLDYRTENQHVPTTSSSLTDPHAGVKAALLQLLAQHQPQDDPKR ENSRNOP00000018431/1-1508 DQRPPEPPEPPPVTEEDLDYRTENQHGPTTSSSLTDPHAGVKAALLQLLAQHQPQDDPKR ************************** .***************************::*** ENSCPOP00000008917/1-1115 EGGIDYPAGDTYVPTSDYKDSFGSSSFSSAPYVSNDGLGSSS-AAPLERRSFIGNSDIQP XP_004921118.1/1-1360 EGGIDYSAGDTYVPTSDYKDSFGTSSFSSAPYVSSDGLGSSS-AAPLERRSFIGNSDIPS ENSP00000181839/1-1512 EGGIDYQAGDTYVSTSDYKDNFGSSSFSSAPYVSNDGLGSSS-APPLERRSFIGNSDIQS ENSMUSP00000036013/1-1511 EGGIDYPTGDTYVPSSDYKDNFG-SSFSAAPYVSSDGLGSSSAAAPLEARSFIGNSDIQS ENSRNOP00000018431/1-1508 EGGIDYSTGDTYVPSSDYKDNFG-ASFSAAPYVSSDGLGSSSAAAPLEARSFIGNSDIQS ****** :*****.:*****.** :***:*****.******* *.*** ********* . ENSCPOP00000008917/1-1115 LDNYSTASSHSGGPPQPSAFSESFPSSVAGYGDIYLNAGPMLFSGDKDHRFEYSHGPIAV XP_004921118.1/1-1360 LDNYSTASSHSGGPPQPSAFSESFPSSVAGYGDIYLNAGPMLFSGDKDHRFEYSHGPIAV ENSP00000181839/1-1512 LDNYSTASSHSGGPPQPSAFSESFPSSVAGYGDIYLNAGPMLFSGDKDHRFEYSHGPIAV ENSMUSP00000036013/1-1511 LDNYSTASSHTGGPPQTSAFTESFASSVAGYGDIYLNAGPMLFSGDKDHRFEYSHGPITV ENSRNOP00000018431/1-1508 LDNYSTASSHTGGPPQTSAFTESFPSSVAGYGDIYLNAGPMLFSGDKDHRFEYSHGPITV **********:*****.***:***.*********************************:* ENSCPOP00000008917/1-1115 LANSNDPSAGPESTHPLPAKMHNYNYGGNLQENPGGPSLMHGQTWTSPAQGPGYSQGYRG XP_004921118.1/1-1360 LANSSDPSTGPESTHPLPAKMHNYNYGGNLQENPGGPSLMHGQTWTSPAQGPGYSQGYRG ENSP00000181839/1-1512 LANSSDPSTGPESTHPLPAKMHNYNYGGNLQENPSGPSLMHGQTWTSPAQGPGYSQGYRG ENSMUSP00000036013/1-1511 LTNSNDPSTGPESTHPLPAKMHNYNYGGNLQENPGGPSLMHGQTWTSPAQGPGYSQGYRG ENSRNOP00000018431/1-1508 LTNSSDPSTGPESTHPLPAKIHNYNYGGNLQENPGGPSLMHGQTWTSPAQGPGYSQGYRG *:**.***:***********:*************.************************* ENSCPOP00000008917/1-1115 HISTSAGRGRGRGLPY XP_004921118.1/1-1360 HIGTSAGRGRGRGLPY ENSP00000181839/1-1512 HISTSTGRGRGRGLPY ENSMUSP00000036013/1-1511 HISTSAGRGRGRGLPY ENSRNOP00000018431/1-1508 HISTSAGRGRGRGLPY **.**:**********