CLUSTAL W(1.81) multiple sequence alignment ENSMUSP00000074516/1-1494 MRILANKTRLPHPRRREAPGSPPLSPRGHCPPAPAKPMHPENKLTNHGKTGNGGAQSQHQ ENSRNOP00000061788/1-1443 MRILANKTRLPHPRRREAPGSPPLSPRGHCPPAPAKPMHPENKLTNHGKTGNGGAQSQHQ ENSP00000335320/1-1499 MRILANKTRLPHPRRREAPGSPPLSPRGHCPPAPAKPMHPENKLTNHGKTGNGGAQSQHQ ENSCPOP00000008786/1-1496 MRILANKTRLPHPRRREAPGSPPLSPRGHCPPAPAKPMHPENKLTNHGKTGNGGAQSQHQ XP_004856790.1/1-1495 MRILANKTRLPHPRRREAPGSPPLSPRGHCPPAPAKPMHPENKLTNHGKTGNGGAQSQHQ ************************************************************ ENSMUSP00000074516/1-1494 NVNQGPTCNLGSKGVGAGSHGAKANQISPSNSSLKNPQAGVSPFSSLKGKVKRERSVSVD ENSRNOP00000061788/1-1443 NVNQGPTCNLGSKGVGAGSHGAKANQISPSNSSLKNPQAGVSPFSSLKGKVKRERSVSVD ENSP00000335320/1-1499 NVNQGPTCNVGSKGVGAGNHGAKANQISPSNSSLKNPQAGVPPFSSLKGKVKRDRSVSVD ENSCPOP00000008786/1-1496 NVNQGPTCNLGSKGVGAGSHGVKANQISPSNSSLKNPQAGVPSFGSLKGKVKRERSVSVD XP_004856790.1/1-1495 NVNQGPTCNLGSKGVGAGSHGAKANQISPSNSSLKNPQAGVPPFSSLKGKVKRERSVSVD *********:********.**.*******************..*.********:****** ENSMUSP00000074516/1-1494 SGEQREAGTPSLDSEAKEVAPRSKRRCVLERKQPYSGDEWCSGPDSEEDDKPIAAAHNCN ENSRNOP00000061788/1-1443 SGEQREAGTPSLDSEAKEVAPRSKRRCVLERKQPYSGDEWCSGPDSEEDDKPIGATHNCN ENSP00000335320/1-1499 SGEQREAGTPSLDSEAKEVAPRSKRRCVLERKQPYSGDEWCSGPDSEEDDKPIGATHNCN ENSCPOP00000008786/1-1496 SGEQREAGTPSLDSEAKEVAPRSKRRCVLERKQPYSGDEWCSGPDSEEDDKPIGAAHNCN XP_004856790.1/1-1495 SGEQREAGTPSLDSEAKEVAPRSKRRCVLERKQPYSGDEWCSGPDSEEDDKPIGASHNCN *****************************************************.*:**** ENSMUSP00000074516/1-1494 VADPAMVTPQLGPGQTAQLPLSESSAPGPQHGPQPGLRPDVPGGGG--GGVPGKPPSQFV ENSRNOP00000061788/1-1443 VADPAMVAPQLGPGQTAQLPLSENSAPGPQHGPPPGLRPDVPGGGG--GGVPGKPPSQFV ENSP00000335320/1-1499 VADPAMAAPQLGPGQTTQLPLSESSVPGAPHGPPPGLRPDAPGGGGGGGGVPGKPPSQFV ENSCPOP00000008786/1-1496 VADPAMAAPQLGPGQTAQLPLNESSAPGAQHGPPPGLRPDGPGAGA--GGVSGKPPSQFV XP_004856790.1/1-1495 VADPAMAAPQLGPSQTAQLPLSESSAPGPPHGPPPGLRPDASGA----GGVPGKPPSQFV ******.:*****.**:****.*.*.**. *** ****** .*. ***.******** ENSMUSP00000074516/1-1494 YVFTTHLANTAAEAVLQGRAESILAYHQQNVPRAKLDQAPKVPPTPEPLPLNTPSAGTPQ ENSRNOP00000061788/1-1443 YVFTTHLANTAAEAVLQGRAESILAYHQQNVPRAKLDQAPKVPPTPEPLPLNTPSAGTPQ ENSP00000335320/1-1499 YVFTTHLANTAAEAVLQGRADSILAYHQQNVPRAKLDQAPKVPPTPEPLPLSTPSAGTPQ ENSCPOP00000008786/1-1496 YVFTTHLANTAADAVLQGRADSILAYHQQNVPRAKLDQAPKVPPTPEPLPLSTPSAGTPQ XP_004856790.1/1-1495 YVFTTHLANTAADAVLQGRADSILAYHQQNVPRAKLDQAPKVPPTPEPLSLSTPSAGTPQ ************:*******:****************************.*.******** ENSMUSP00000074516/1-1494 SQPPPLPPPP-PAPGSAPPALPPEGPPEDTSQDLAPNSVGAASTGGGTGGTHPNTPTAAT ENSRNOP00000061788/1-1443 SQPPPLPPPP-PAPGSAPPALPQEGPPEDTSQDLAPNSVGAASTGGGTGGTHPNTPTAAT ENSP00000335320/1-1499 SQPPPLPPPPPPAPGSAPPALPPEGPPEDSSQDLAPNSVGAASTGGGTGGTHPNTPTATT ENSCPOP00000008786/1-1496 SQPPPLPPPPAPAPGSAPPALPPEGPPEDTSQDLAPNSVGAASTGGGTGGTHPNTPTAAT XP_004856790.1/1-1495 SQPPPLPPPPPPAPGSAPPALPPEGPPEDTSQDLAPNSVGAASTGGGTGGTHPNTPTAAT ********** *********** ******:****************************:* ENSMUSP00000074516/1-1494 ANNPLPPGGDPGSAPGSALLGEATPTGNGQRNLVGSEGLSKEQLEHRERSLQTLRDIERL ENSRNOP00000061788/1-1443 ANNPLPPGGDPGSAPGSALLGEATPTGNGQRNLVGSEGLSKEQLEHRERSLQTLRDIERL ENSP00000335320/1-1499 ANNPLPPGGDPSSAPGPALLGEAAAPGNGQRSLVGSEGLSKEQLEHRERSLQTLRDIERL ENSCPOP00000008786/1-1496 ANNPLPPGGDPGSASGPGLLREATPTGNGQRNLVGSEGLSKEQLEHRERSLQTLRDIERL XP_004856790.1/1-1495 ANNPLPPGGDPGSAPGPALLGEATPTGNGQRSLVGSEGLSKEQLEHRERSLQTLRDIERL ***********.**.*..** **:..*****.**************************** ENSMUSP00000074516/1-1494 LLRSGETEPFLKGPPGGAGEGGPPAQAPSAAQPPPSAPPGGLKKYEEPLQSMISQTQSLG ENSRNOP00000061788/1-1443 LLRSGETEPFLKGPPGGAVEGGPPAQAPSAAQQPPSAPPPGLKKYEEPLQSMISQTQSLG ENSP00000335320/1-1499 LLRSGETEPFLKGPPGGAGEGGPPAQAPPPPQQPPTAPPSGLKKYEEPLQSMISQTQSLG ENSCPOP00000008786/1-1496 LLRSGETEPFLKGPPGGAGEGGPPAQAPSASQQPPTAPPGGLKKYEEPLQSMISQTQSLG XP_004856790.1/1-1495 LLRSGETEPFLKGPPGGAGEGGPPAQAPSAAQQPLTAPPSGLKKYEEPLQSMISQTQSLG ****************** *********...* * :*** ******************** ENSMUSP00000074516/1-1494 GPPLEHEVPGHPQGGDMGQQMNMMMQRLGQDSLTPEQVAWRKLQEEYYEEKRRKEEQIGL ENSRNOP00000061788/1-1443 GPPLEHEVPGHPQGGDMGQQMNMMMQRLGQDSLTPEQVAWRKLQEEYYEEKRRKEEQIGL ENSP00000335320/1-1499 GPPLEHEVPGHPPGGDMGQQMNMMIQRLGQDSLTPEQVAWRKLQEEYYEEKRRKEEQIGL ENSCPOP00000008786/1-1496 GPPLEHEVPGHPPGGDMGQQMNMMMQRLGQDSLTPEQVAWRKLQEEYYEEKRRKEEQIGL XP_004856790.1/1-1495 APPLEHEVPGHPPGGDMGQQMNMMMQRLGQDSLTPEQVAWRKLQEEYYEEKRRKEEQIGL .*********** ***********:*********************************** ENSMUSP00000074516/1-1494 HGGRPLQDMVGMGGMMGRGPPPPYHSKPGDQWPPGMGAQLRGPMDVQDPMQLRPGPPFPG ENSRNOP00000061788/1-1443 HGGRPLQDMVGMG----------------------------------------------- ENSP00000335320/1-1499 HGSRPLQDMMGMGGMMVRGPPPPYHSKPGDQWPPGMGAQLRGPMDVQDPMQLRGGPPFPG ENSCPOP00000008786/1-1496 HGGRPLQDMMGMGGMMVRGPPPPYHSKPGDQWPPGMGAQLRGPMDVQDAMQLRGGPPFPG XP_004856790.1/1-1495 HGGRPLQDMMGMGGMMVRGPPPPYHSKPGDQWPPGMGTQLRGPMDVQDPMQLRGGSPFPG **.******:*** ENSMUSP00000074516/1-1494 PRFPGNQMQRVPGFGGMQSMPMEVPMNAMQRPVRPGMAWNEDLPPIGGPSNFAQNAVPYP ENSRNOP00000061788/1-1443 ----GNQMQRVPGFGGMQSIPMEVPMNAMQRPVRPGMAWNEDLPPIGGPSNFAQNAVPYP ENSP00000335320/1-1499 PRFPGNQIQRVPGFGGMQSMPMEVPMNAMQRPVRPGMGWTEDLPPMGGPSNFAQNTMPYP ENSCPOP00000008786/1-1496 PRFPGNQMQRVPGFGGMQSMPMEVPMNAMQRPVRPGMGWTEDLPPMGGPSNFAQNAVPYP XP_004856790.1/1-1495 PRFPGNQMQRVPGFGAMQSMPMEVPMNAMQRPVRPGMGWTEDLPPMGGPSNFAQNAVPYP ***:*******.***:*****************.*.*****:*********::*** ENSMUSP00000074516/1-1494 GGQGEAERFMTPRVREELLRHQLLEKRSMGMQRPLGMAGSGMGQSMEMERMIQAHRQMDP ENSRNOP00000061788/1-1443 GGQGEAERFMTPRVREELLRHQLLEKRSMGMQRPLGMAGSGMGQSMEMERMIQTHRQMDP ENSP00000335320/1-1499 GGQGEAERFMTPRVREELLRHQLLEKRSMGMQRPLGMAGSGMGQSMEMERMMQAHRQMDP ENSCPOP00000008786/1-1496 GGQGEAERFMTPRVREELLRHQLLEKRSMGMQRPLGMAGSSMGQSMEMERMMQAHRQMDP XP_004856790.1/1-1495 GGQGEVERFMTPRVREELLRHQLLEKRSMGMQRPLGMAGSGMGQSMEMERMMQAHRQMDP *****.**********************************.**********:*:****** ENSMUSP00000074516/1-1494 AMFPGQMTGGDGLAGTPMGIEFGGGRGLLSPPMGQSGLREVDPPMGPGNLNMNMNVNMNM ENSRNOP00000061788/1-1443 TMFPGQMTGGDGLAGTPMGIEFGGGRGLLSPPMGQSGLREVDPPMGPGNLNMNMNVNMNM ENSP00000335320/1-1499 AMFPGQMAGGEGLAGTPMGMEFGGGRGLLSPPMGQSGLREVDPPMGPGNLNMNMNVNMNM ENSCPOP00000008786/1-1496 TMFPGQMAGGEGLAGTPMGMEFGGGRGLLSPPMGQSGLREVDAPMGPGNLNMNMNVNMNM XP_004856790.1/1-1495 TMFPGQMAGGEGLAGTPMGMEFGGGRGLLSPPMGQSGLREVDPPMGPGNLNMNMNVNMNM :******:**:********:**********************.***************** ENSMUSP00000074516/1-1494 NMNLNVQMTPQQQMLMSQKMRGPGDMMGPQGLSPEEMARVRAQNSSGMMGGPQKMLMPSQ ENSRNOP00000061788/1-1443 NMNLNVQMTPQQQMLMSQKMRGPGDMMGPQGLSPEEMARVRAQNSSGMMAGPQKMLMPSQ ENSP00000335320/1-1499 NMNLNVQMTPQQQMLMSQKMRGPGDLMGPQGLSPEEMARVRAQNSSGVMGGPQKMLMPSQ ENSCPOP00000008786/1-1496 NMNLNVQMTPQQQMLMSQKMRGPGDMMGPQGLSPEEMARVRAQNSSGMMSGPQKMLMPSQ XP_004856790.1/1-1495 NMNLNVQMTPQQQMLMSQKMRGPGDMMGPQGLSPEEIARVRAQNSSSMMGGPQKMLMPSQ *************************:**********:*********.:*.********** ENSMUSP00000074516/1-1494 FPNQGQQGFSGGQGPYQAMPQDMGNTPDMFSPDQSSVPMGTVGTARLSHMPLPPASNPPG ENSRNOP00000061788/1-1443 FPNQGQQGFSGGQGPYQAMPQDMGNTPDMFSPDQSSVPMGAVGTARLSHMPLPPASNPPG ENSP00000335320/1-1499 FPNQGQQGFSGGQGPYQAMSQDMGNTQDMFSPDQSSMPMSNVGTTRLSHMPLPPASNPPG ENSCPOP00000008786/1-1496 FPNQGQQGFSGGQGPYQAMPQDMGNAQDMFSPDQGSIPMGSVGTTRLSHMPLPAASNPPG XP_004856790.1/1-1495 FPNQGQQGFSGGQGPYQAMPQDMGNTQDMFSPDQGSMPMGTVGTTRLSHMPLAAASNPPG *******************.*****: *******.*:**. ***:*******..****** ENSMUSP00000074516/1-1494 SVHLASNRGLGRRPSDLTISINQMGSPGMGHLKSPTLSQVHSPLVTSPSANLKSPQTPSQ ENSRNOP00000061788/1-1443 SVHSAPNRGLGRRPSDLTISINQMGSPGMGHLKSPTLSQVHSPLVTSPSANLKSPQTPSQ ENSP00000335320/1-1499 TVHSAPNRGLGRRPSDLTISINQMGSPGMGHLKSPTLSQVHSPLVTSPSANLKSPQTPSQ ENSCPOP00000008786/1-1496 SVHSAPNRGLGRRPSDLTISINQMGSPGMGHLKSPTLNQVHSPLVTSPSANLKSPQTPSQ XP_004856790.1/1-1495 SVHSAPNRGLGRRPSDLTISINQMGSPGMGHLKSPTLSQVHSPLVTSPSANLKSPQTPSQ :** *.*******************************.********************** ENSMUSP00000074516/1-1494 MVPLPSANPPGPLKSPQVLSSSLGVRSPTGSPSRLKSPSMAVPSPGWVASPKTAMPSPGV ENSRNOP00000061788/1-1443 MVPLPSANPPGPLKSPQVLSSSLSVRSPTGSPSRLKSPSMAVPSPGWVASPKTAMPSPGV ENSP00000335320/1-1499 MVPLPSANPPGPLKSPQVLGSSLSVRSPTGSPSRLKSPSMAVPSPGWVASPKTAMPSPGV ENSCPOP00000008786/1-1496 MVPLPSANPPGPLKSPQVLSSSLNVRSPTGSPSRLKSPSMAVPSPGWAASPKTAMPSPGV XP_004856790.1/1-1495 MVPLASANPPGPLKSPQVLSSSLNVRSPTGSPSRLKSPSMAVPSPGWVSSPKTAMPSPGV ****.**************.***.***********************.:*********** ENSMUSP00000074516/1-1494 SQNKQPPLSINSSSTLGNVEQGALPPSAPRNSSSAPPANPSSGLMNPSLPFTSSPDPTPS ENSRNOP00000061788/1-1443 SQNKQPPLNINSSSTLGNLEQGALPPAGPRNSSSAPPANPPSSLMNPSLPFTSSPDPTPS ENSP00000335320/1-1499 SQNKQPPLNMNSSTTLSNMEQGTLPPSGPRSSSSAPPANPPSGLMNPSLPFTSSPDPTPS ENSCPOP00000008786/1-1496 SQNKQPPLSMNSS-TMGNMEQGALPASGPRNSSSAPPANPPSSLMNPSLPFTSSPDPTPS XP_004856790.1/1-1495 SQNKQPPLNMNSSSTLTNMEQGALPPSGPRSSSSAPPANPPSSLMNPSLPFTSSPDPTPS ********.:*** *: *:***:**.:.**.*********.*.***************** ENSMUSP00000074516/1-1494 QNPLSLMMSQMSKYAMPSSTPLYHNAIKTIATSDDELLPDRPLLPPPPPPQGSGPGISNN ENSRNOP00000061788/1-1443 QNPLSLMMSQMSKYAMPSSTPLYHNAIKTIATSDDELLPDRPLLPPPPPPQGSGPGISNN ENSP00000335320/1-1499 QNPLSLMMTQMSKYAMPSSTPLYHNAIKTIATSDDELLPDRPLLPPPPPPQGSGPGISNS ENSCPOP00000008786/1-1496 QNPLSLMMSQMSKYAMPSSTPLYHNAIKTIATSDDELLPDRPLLPPPPPPQGSGPGISNN XP_004856790.1/1-1495 QNPLSLMMSQMSKYAMPSSTPLYHNAIKTIATSDDELLPDRPLLPPPPPPQGSGPGISNN ********:**************************************************. ENSMUSP00000074516/1-1494 QPNQMHMNPAAAQSPMGMNLPGQQPLSHEPPPTMLPSPTPLGSNIPLHPNAQGTGGSSQN ENSRNOP00000061788/1-1443 QPNQMHMNPAAAQSPMGMNLPGQQPLSHEPPPTMLPSPTPLGSNIPLHPNAQGTGGPSQN ENSP00000335320/1-1499 QPSQMHLNSAAAQSPMGMNLPGQQPLSHEPPPAMLPSPTPLGSNIPLHPNAQGTGGPPQN ENSCPOP00000008786/1-1496 QPNQMHLNSAAAQSPMGMNLPGQQPLSHEPPPTMLPSPTPLGSNIPLHPNAQGAGGPPQN XP_004856790.1/1-1495 QPNQMHLNSTAAQSPMAMNLPGQQPLSHEPPPTMLPSPTPLGSNIPLHPNAQGAGGPPQN **.***:*.:******.***************:********************:**..** ENSMUSP00000074516/1-1494 SMMMAPGGPDSLNAPCGPVPSSSQMMSFPPRLQQPHGAMAPT--GAGGPGLQQHYPSGMA ENSRNOP00000061788/1-1443 SMMMAPGGPDSLNTPCGPVPSSSQMMSFPPRLQQPHGAMAAT--GGGGPGLQQHYPSGMA ENSP00000335320/1-1499 SMMMAPGGPDSLNAPCGPVPSSSQMMPFPPRLQQPHGAMAPTGGGGGGPGLQQHYPSGMA ENSCPOP00000008786/1-1496 SMMLAPGGPDSLNAPCGPVPSSSQMMPFPPRLQQPHGAMTPAGGGGGGPGLQQHYPSGIP XP_004856790.1/1-1495 SMMMAPGGPDSLNAPCGPVPSSSQMMPFPPRLQQPHGAMAPAGGGGGGPGLQQHYPSGMP ***:*********:************.************:.: *.************:. ENSMUSP00000074516/1-1494 LPPEDLPTQPPGPIPPQQHLMGKGMTGRMGDAYPPGVLPGVASVLNDPELSEVIRPTPTG ENSRNOP00000061788/1-1443 LPPEDLPNQPPGPIPSQQHLMGKGMAGRMGDAYPPGVLPGVASVLNDPELSEVIRPTPTG ENSP00000335320/1-1499 LPPEDLPNQPPGPMPPQQHLMGKAMAGRMGDAYPPGVLPGVASVLNDPELSEVIRPTPTG ENSCPOP00000008786/1-1496 LPPEDMPSQPPGPMPPQQHLMGKGMAGRMGDAYPPGVLPGVASVLNDPELSEVIRPTPTG XP_004856790.1/1-1495 LPPEDMPSQPAGPMPPQHHLMGKGMAGRMGDAYPPGVLPGVASVLNDPELSEVIRPTPTG *****:*.**.**:*.*:*****.*:********************************** ENSMUSP00000074516/1-1494 IPEFDLSRIIPSEKPSSTLQYFPKSENQPPKAQPPNLHLMNLQNMMAEQTPSRPPNLPGQ ENSRNOP00000061788/1-1443 IPEFDLSRIIPSEKPSSTLQYFPKNENQPPKAQPPNLHLMNLQNMMAEQAPSRPPNLPGQ ENSP00000335320/1-1499 IPEFDLSRIIPSEKPSSTLQYFPKSENQPPKAQPPNLHLMNLQNMMAEQTPSRPPNLPGQ ENSCPOP00000008786/1-1496 IPEFDLSRIIPSEKPSSTLQYFPKSENQPPKAQPPNLHLMNLQNMMAEQTPSRPPNLPGQ XP_004856790.1/1-1495 IPEFDLSRIIPSEKPSSTLQYFPKSENQPAKAQPPNLHLMNLQNMMAEQTPSRPPNLPGQ ************************.****.*******************:********** ENSMUSP00000074516/1-1494 QGVQRGLSMSMCHPGQMSLLGRTGVPPQQGMVPHGLHQGVMSPPQGLMTQQNFMLMKQRG ENSRNOP00000061788/1-1443 QGVQRGLSMSMCHPGQMSLLGRTGVPPQQGMVPHGLHQGVMSPPQGLMTQQNFMLMKQRG ENSP00000335320/1-1499 QGVQRGLNMSMCHPGQMSLLGRTGVPPQQGMVPHGLHQGVMSPPQGLMTQQNFMLMKQRG ENSCPOP00000008786/1-1496 QGVQRGLNMSMCHPGQMSLLGRTGVPPQQGMVPHGLHQGVMSPPQGLMTQQNFMLMKQRG XP_004856790.1/1-1495 QGVQRGLNMSMCHPGQMSLLGRTGVPPQQGMVPHGLQQGVMSPPQGLMTQQNFMLMKQRG *******.****************************:*********************** ENSMUSP00000074516/1-1494 VGGEVYTQPPHMLSPQGSLMGPPPQQNLMVSHPLRQRSVSLDSQMGYLPTPGSMANLPF ENSRNOP00000061788/1-1443 VGGEVYTQPPHMLSPQGSLMAPPPQQNLMVSHPLRQRSVSLDSQMGYLPTPGGMANLPF ENSP00000335320/1-1499 VGGEVYSQPPHMLSPQGSLMGPPPQQNLMVSHPLRQRSVSLDSQMGYLPAPGGMANLPF ENSCPOP00000008786/1-1496 VGGEVYSQPPHMLSPQGSLMGPPSQQNLMVSHPLRQRSVSLDSQMGYLPAPGSMANLPF XP_004856790.1/1-1495 VGGEVYTQPPHMLSPQGSLMGPPPQQNLMVSHPLRQRSVSLDSQIGYLPAPGSMANLPF ******:*************.**.********************:****:**.******