CLUSTAL W(1.81) multiple sequence alignment XP_004851986.1/1-933 ------------------------------MSA--------------------------- ENSP00000412178/1-1117 METFFRRHFRGKVPGPGEGQQRPSSVGLPTGKARRRSPAGQASSSLAQRRRSSAQLQGCL ENSMUSP00000106934/1-1123 METFFRKHFQRKARGPGERQRRSSGVGLPTGKARRRSPAGQASSSLAQRRRSSAQLQGCF ENSCPOP00000008649/1-931 ------------------------------MEPRDGSPEARSSDS--------------- ENSRNOP00000024280/1-929 ------------------------------MEPRDPSPEARSSDS--------------- .. XP_004851986.1/1-933 LGAG-GSAGGDRDAAAALGP---------------------------------------- ENSP00000412178/1-1117 LSCGVRAQGSSRRRSSTVPPSCNPRFIVDKVLTPQPTTVGAQLLGAPLLLTGLVGMNEEE ENSMUSP00000106934/1-1123 PSCGVGTRGASRRRSSTAPPTCNPRFMVDVVPTLQPVTVGAQLLGAPLLLAGLTSMKEEE ENSCPOP00000008649/1-931 ESASASSSGSERDA---------------------------------------------- ENSRNOP00000024280/1-929 ESASASSSGSERDA---------------------------------------------- ... : *..* XP_004851986.1/1-933 ----------------AEVPGTEA------------------------------------ ENSP00000412178/1-1117 G----VQEDVVAEASSAIQPGTKTPGPPPPRGAQPLLPLPRYLRRASSHLLPADAVYDHA ENSMUSP00000106934/1-1123 EEEGVQEGNETAEATSDARPGTRT-TPFSHQGTWPLLPMPRCLRRASSHLLPADVECGHT ENSCPOP00000008649/1-931 ----------------GPEPDKAL------------------------------------ ENSRNOP00000024280/1-929 ----------------DPEPDKAP------------------------------------ *.. XP_004851986.1/1-933 --------REL---------PGP-------------------LRQMWRYRSWDVPQIPAE ENSP00000412178/1-1117 LWGLHGYYRRLSQRRPSGQHPGPGGR--RASGTTAGTMLPTRVRPLSRRRQVALRRKAAG ENSMUSP00000106934/1-1123 LWGLHGHYRRLSQRWPSGQHPGLGGRSPRASGAAACPMIPARVRPLSRRRQVALRRKSAG ENSCPOP00000008649/1-931 --------RRLSKRRF----PG--------------------LRLFGHR----------- ENSRNOP00000024280/1-929 --------RRLTKRRF----PG--------------------LRLFGHR----------- *.* ** :* : : XP_004851986.1/1-933 APQTQ----KATTKSGLQHLAPPPPTLGAPCGESERQIRSTVDWS-SATYGEHIWFETNV ENSP00000412178/1-1117 PQAWSALLAKAITKSGLQHLAPPPPTPGAPCSESERQIRSTVDWSESATYGEHIWFETNV ENSMUSP00000106934/1-1123 PQPWSTLLMKAITKSGLQHLAPPPPTPGAPCGESEEQIQSTVDWSESAVYGEHIWFETNV ENSCPOP00000008649/1-931 ---------KAITKSGLQHLAPPPPTLGAPCGESERQIRSTVDWSESATYGEHIWFETNV ENSRNOP00000024280/1-929 ---------KAITKSGLQHLAPPPPTPGAPCGESERQIRSTVDWSESAAYGEHIWFETNV ** ************** ****.***.**:****** **.*********** XP_004851986.1/1-933 SGDFCYVGEQYCVAKMLQKSVPRKKCAACKIVVHTPCIEQLEKINFRCKPSFRESGSRNV ENSP00000412178/1-1117 SGDFCYVGEQYCVARML-KSVSRRKCAACKIVVHTPCIEQLEKINFRCKPSFRESGSRNV ENSMUSP00000106934/1-1123 SGDFCYVGEQHCVAKMLPKSAPRKKCAACKIVVHTQCIKQLEKINFRCKPSFRESGSRNV ENSCPOP00000008649/1-931 SGDFCYVGEQYCVAKMLQKSVPRKKCAACKIVVHTPCIEQLEKINFRCKPSFRESGSRNI ENSRNOP00000024280/1-929 SGDFCYVGEQYCVAKMLPKSAPRRKCAACKIVVHTPCIGQLEKINFRCKPSFRESGSRNV **********:***:** **..*:*********** ** ********************: XP_004851986.1/1-933 REPTFVRHHWVHRRRQDGKCRHCGKGFQQKFTFHSKEIVAISCSWCKQAYHSKVSCFMLQ ENSP00000412178/1-1117 REPTFVRHHWVHRRRQDGKCRHCGKGFQQKFTFHSKEIVAISCSWCKQAYHSKVSCFMLQ ENSMUSP00000106934/1-1123 REPTFVRHHWVHRRRQDGKCRHCGKGFQQKFTFHSKEIVAISCSWCKQAYHSKVSCFMMQ ENSCPOP00000008649/1-931 REPTFVRHHWVHRRRQDGKCRHCGKGFQQKFAFHSKEIVAISCSWCKQAYHSKVSCFMLQ ENSRNOP00000024280/1-929 REPTFVRHHWVHRRRQDGKCRHCGKGFQQKFTFHSKEIVAISCSWCKQAYHSKVSCFMLQ *******************************:**************************:* XP_004851986.1/1-933 QIEEPCSLGVHAALVIPPTWILRARRPQNTLKASKKKKRASFKRKSSKKGPEESRWRPFI ENSP00000412178/1-1117 QIEEPCSLGVHAAVVIPPTWILRARRPQNTLKASKKKKRASFKRKSSKKGPEEGRWRPFI ENSMUSP00000106934/1-1123 QIEEPCSLGVHAAVVIPPTWILRARRPQNTLKASKKKKRASFKRRSSKKGPEEGRWRPFI ENSCPOP00000008649/1-931 QIEEPCSLGVHAAVVIPPTWILRARRPQNTLKASKKKKRASFKRKSSKKGPEESRWRPFI ENSRNOP00000024280/1-929 QIEEPCSLGVHAAVVIPPTWILRARRPQNTLKASKKKKRASFKRRSSKKGPEEGRWRPFI *************:******************************:********.****** XP_004851986.1/1-933 IRPTPSPLMKPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVFDLSQGGPKEALEMYRKVH ENSP00000412178/1-1117 IRPTPSPLMKPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVFDLSQGGPKEALEMYRKVH ENSMUSP00000106934/1-1123 IRPTPSPLMKPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVFDLSQGGPREALEMYRKVH ENSCPOP00000008649/1-931 IRPTPSPLMKPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVFDLSQGGPKEALEMYRKVH ENSRNOP00000024280/1-929 IRPTPSPLMKPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVFDLSQGGPREALEMYRKVH *************************************************:********** XP_004851986.1/1-933 NLRILACGGDGTVGWILSTLDQLRLKPPPPVAILPLGTGNDLARTLNWGGGYTDEPVSKI ENSP00000412178/1-1117 NLRILACGGDGTVGWILSTLDQLRLKPPPPVAILPLGTGNDLARTLNWGGGYTDEPVSKI ENSMUSP00000106934/1-1123 NLRILACGGDGTVGWILSTLDQLRLKPPPPVAILPLGTGNDLARTLNWGGGYTDEPVSKI ENSCPOP00000008649/1-931 NLRILACGGDGTVGWILSTLDQLRLKPPPPVAILPLGTGNDLARTLNWGGGYTDEPVSKI ENSRNOP00000024280/1-929 NLRILACGGDGTVGWILSTLDQLRLKPPPPVAILPLGTGNDLARTLNWGGGYTDEPVSKI ************************************************************ XP_004851986.1/1-933 LSHVEEGNVVQLDRWDLCAEPNPDAGPEERDEGATDRLPLDVFNNYFSLGFDAHVTLEFH ENSP00000412178/1-1117 LSHVEEGNVVQLDRWDLHAEPNPEAGPEDRDEGATDRLPLDVFNNYFSLGFDAHVTLEFH ENSMUSP00000106934/1-1123 LSHVEEGNVVQLDRWDLRAEPNPEAGPEERDDGATDRLPLDVFNNYFSLGFDAHVTLEFH ENSCPOP00000008649/1-931 LSHVEEGNVVQLDRWDLRAEPNPEAGPEERDEGATDRLPLDVFNNYFSLGFDAHVTLEFH ENSRNOP00000024280/1-929 LSHVEEGNVVQLDRWDLRAEPNPEAGPEERDDGATDRLPLDVFNNYFSLGFDAHVTLEFH ***************** *****:****:**:**************************** XP_004851986.1/1-933 ESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIRVVCDGMDLTPKIQDLKPQC ENSP00000412178/1-1117 ESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIRVVCDGMDLTPKIQDLKPQC ENSMUSP00000106934/1-1123 ESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIRVVCDGMDLTPKIQDLKPQC ENSCPOP00000008649/1-931 ESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIRVVCDGMDLTPKIQDLKPQC ENSRNOP00000024280/1-929 ESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIRVVCDGMDLTPKIQDLKPQC ************************************************************ XP_004851986.1/1-933 IVFLNIPRYCAGTMPWGHPGEHHDFEPQRHDDGYLEVIGFTMTSLAALQVGGHGERLTQC ENSP00000412178/1-1117 VVFLNIPRYCAGTMPWGHPGEHHDFEPQRHDDGYLEVIGFTMTSLAALQVGGHGERLTQC ENSMUSP00000106934/1-1123 IVFLNIPRYCAGTMPWGHPGEHHDFEPQRHDDGYLEVIGFTMTSLAALQVGGHGERLTQC ENSCPOP00000008649/1-931 IVFLNIPRYCAGTMPWGHPGEHHDFEPQRHDDGYLEVIGFTMTSLAALQVGGHGERLTQC ENSRNOP00000024280/1-929 IVFLNIPRYCAGTMPWGHPGEHHDFEPQRHDDGYLEVIGFTMTSLAALQVGGHGERLTQC :*********************************************************** XP_004851986.1/1-933 REVLLTTAKAIPVQVDGEPCKLSASRIRIALRNQATMVQKAKRRSAAPLHSDQQPVPEQL ENSP00000412178/1-1117 REVVLTTSKAIPVQVDGEPCKLAASRIRIALRNQATMVQKAKRRSAAPLHSDQQPVPEQL ENSMUSP00000106934/1-1123 REVLLTTAKAIPVQVDGEPCKLSASRIRIALRNQATMVQKAKRRSTAPLHSDQQPVPEQL ENSCPOP00000008649/1-931 REVLLTTAKAIPVQVDGEPCKLAASRIRIALRNQATMVQKAKRRSAAPLHSDQQPVPEQL ENSRNOP00000024280/1-929 REVLLTTAKAIPVQVDGEPCKLAASRIRIALRNQATMVQKAKRRSTAPLHSDQQPVPEQL ***:***:**************:**********************:************** XP_004851986.1/1-933 RIQVSKVSMHDYEALHYDKEQLKEASVPLGTVVVPGDSDLELCRAHIERLQQESDGAGAK ENSP00000412178/1-1117 RIQVSRVSMHDYEALHYDKEQLKEASVPLGTVVVPGDSDLELCRAHIERLQQEPDGAGAK ENSMUSP00000106934/1-1123 RIQVSRVSMHDYEALHYDKEQLKEASVPLGTVVVPGDSDLELCRAHIERLQREPDGAGAK ENSCPOP00000008649/1-931 RIQVSRVSMHDYEALHYDKEQLKEASVPLGTVVVPGDSDLELCRAHIEKLQQESDGAGAK ENSRNOP00000024280/1-929 RIQVSRVSMHDYEALHYDKEQLKEASVPLGTVVVPGDSDLELCRAHIERLQQEPDGAGAK *****:******************************************:**:*.****** XP_004851986.1/1-933 SPTCQKLSPKWCFLDATTASRFYRIDRAQEHLNYVTEIAQDEIYILDPELLGASAQPDLP ENSP00000412178/1-1117 SPTCQKLSPKWCFLDATTASRFYRIDRAQEHLNYVTEIAQDEIYILDPELLGASARPDLP ENSMUSP00000106934/1-1123 SPMCHQLSSKWCFLDATTASRFYRIDRAQEHLNYVTEIAQDEIYILDPELLGASARPDLP ENSCPOP00000008649/1-931 SPTCQKLSPKWCFLDATTASRFYRIDRAQEHLNYVTEIAQDEIYILDPELLGASARPDPV ENSRNOP00000024280/1-929 SPMCHPLSSKWCFLDATTASRFYRIDRAQEHLNYVTEIAQDEIYILDPELLGASARPDLP ** *: **.**********************************************:** XP_004851986.1/1-933 PPPSPLPASP-CSPTPR-SLQGDTVPPPGEALMEAAQRNDFCKLQELHRAGGDLLHRDSR ENSP00000412178/1-1117 TPTSPLPTSP-CSPTPR-SLQGDAAPPQGEELIEAAKRNDFCKLQELHRAGGDLMHRDEQ ENSMUSP00000106934/1-1123 TPTSPLPASP-CSPTPG-SMQGDTALPQGEELIEAAKRNDCCKLQELHRAGGDLMHRDQK ENSCPOP00000008649/1-931 SPRTPAPLSPGCIPVCSWSLQGDTVPPPGEALIEAAQRNDFCKLQELHRAGGDLVHRDSR ENSRNOP00000024280/1-929 TPTSPLPASP-CSPTPG-SLQGDAALPQGEELIEAAKRNDFCKLQELHRAGGDLMHRDHQ .* :* * ** * *. *:***:. * ** *:***:*** *************:*** : XP_004851986.1/1-933 GRTLLHHAVSAGSKEVVRYLLDHAPPEILDAVEENGETCLHQAAALGQRTICHFIVEAGA ENSP00000412178/1-1117 SRTLLHHAVSTGSKDVVRYLLDHAPPEILDAVEENGETCLHQAAALGQRTICHYIVEAGA ENSMUSP00000106934/1-1123 SRTLLHHAVSTGSKEVVRYLLDHAPPEILDAVEENGETCLHQAAALGQRTICHYIVEAGA ENSCPOP00000008649/1-931 GRTLLHHAVSAGSKEVVRYLLDHAPPEILDAVEENGETCLHQAAALGQRTICHYIVEAGA ENSRNOP00000024280/1-929 SRTLLHHAVSTGSKEVVRYLLDHAPPEILDAVEENGETCLHQAAALGQRTICHYIVEAGA .*********:***:**************************************:****** XP_004851986.1/1-933 SLMKTDQQGDTARQRAEKAQDTELAAYLENRQHYQMIQREDQETAV ENSP00000412178/1-1117 SLMKTDQQGDTPRQRAEKAQDTELAAYLENRQHYQMIQREDQETAV ENSMUSP00000106934/1-1123 SLMKTDLQGDTPRQRAEKAQDTELAAYLENRQHYQMIQREDQETAV ENSCPOP00000008649/1-931 SLMKTDQQGDTPRQRAEKAQDTELAAYLENRQHYQMIQREDQETAV ENSRNOP00000024280/1-929 SLMKTDQQGDTPRQRAEKAQDTELAAYLENRQHYQMIQREDQETAV ****** ****.**********************************