CLUSTAL W(1.81) multiple sequence alignment ENSMUSP00000099718/1-1032 -----MAAEARCRPRSRG-IALREAVML----LLYFGVPTGHSYNLDPENALLYQGPSGT ENSRNOP00000006880/1-1036 -----MAAEAMCRPRPRG-VALQEAVMLLLYFGVHFRVPTGHSYNLDPESALLYQGPSGT ENSP00000380227/1-1032 -----MAWEARREPGPRR-AAVRETVML----LLCLGVPTGRPYNVDTESALLYQGPHNT ENSCPOP00000008508/1-1035 -----PAARAPRRARPHP-QAARETVMLLLLQLLCLRVPGGQPYNVDTESALLYPGAPGT XP_004868219.1/1-1041 MFPSRSAWLLQRGAEPDPAAAVRGAVLLLL--LLCLRVPGAHPYNVDAESALLFRGAPGT * . . * : :*:* : : ** .:.**:*.*.***: *. .* ENSMUSP00000099718/1-1032 LFGYSVVLHSHGSKRWLIVGAPTASWLSNASVVNPGAIYRCGIRKNPNQTCEQLQLGSPS ENSRNOP00000006880/1-1036 LFGYSVVLHSHGTKRWLIVGAPTASWLANASVVNPGAIYRCRIGKNPNQICEQLQLGSPS ENSP00000380227/1-1032 LFGYSVVLHSHGANRWLLVGAPTANWLANASVINPGAIYRCRIGKNPGQTCEQLQLGSPN ENSCPOP00000008508/1-1035 LFGYSVVLHSHGADRWWKRGAQRAAQLALSARAPPGDL-QMQDRKDPNRTCEQLQLGSPT XP_004868219.1/1-1041 LFGYSVVLHSHGPDRWLVVGAPTATWLANASVLSPGAIYKCRIGKNPSRTCEQLQLGSPT ************..** ** * *: :: ** : : *:*.: *********. ENSMUSP00000099718/1-1032 GEPCGKTCLEERDNQWLGVTLSRQPGENGSIVTCGHRWKNIFYMKSDNKLPTGICYVMPS ENSRNOP00000006880/1-1036 GEPCGKTCLEERDNQWLGVTISRQPGENGSIVTCGHRWKNIFYMKNNNKLPTGVCYGMPS ENSP00000380227/1-1032 GEPCGKTCLEERDNQWLGVTLSRQPGENGSIVTCGHRWKNIFYIKNENKLPTGGCYGVPP ENSCPOP00000008508/1-1035 GEPCGKTCLEERDNQWLGVTLSRQLPCFVSLVTCGHRWKNIFYIKNENKLPTGVCYGMPS XP_004868219.1/1-1041 GEPCGKTCLEERDNQWLGVTLSRQPGENGSIVTCGHRWKNIFYVRHENKLPTGVCYGMPS ********************:*** *:************:: :****** ** :*. ENSMUSP00000099718/1-1032 DLRTELSKRMAPCYKDYTRKFGENFASCQAGISSFYTQDLIVMGAPGSSYWTGTVFVYNI ENSRNOP00000006880/1-1036 DLRTELSKRMAPCYQDFVRKFGENFASCQAGISSFYTQDLIVMGAPGSSYWTGSVFVYNI ENSP00000380227/1-1032 DLRTELSKRIAPCYQDYVKKFGENFASCQAGISSFYTKDLIVMGAPGSSYWTGSLFVYNI ENSCPOP00000008508/1-1035 DLRTELSKRMAPCYQDYVRKFGENFASCQAGISSFFTEDLIVMGAPGSSYWTGSLFVYNI XP_004868219.1/1-1041 DLRTELSKRMAPCYQDYVRKFGENFASCQAGISSFFTEDLIVMGAPGSSYWTGSLFVYNI *********:****:*:.:****************:*:***************::***** ENSMUSP00000099718/1-1032 TTNQYKAFVDRQNQVKFGSYLGYSVGAGHFRSPHTTEVVGGAPQHEQIGKAYIFSIDENE ENSRNOP00000006880/1-1036 TTNKYKAFVDRQNQVKFGSYLGYSVGAGHFRNPHTTEVVGGAPQHEQIGKAYIFSIDESE ENSP00000380227/1-1032 TTNKYKAFLDKQNQVKFGSYLGYSVGAGHFRSQHTTEVVGGAPQHEQIGKAYIFSIDEKE ENSCPOP00000008508/1-1035 TTNKYKAFLDKQNQVKFGSYLGYSVGAGHFRGQHTTEVVGGAPQHEQIGKAYIFSIDAKE XP_004868219.1/1-1041 TTNKYKAFVDKHNQVKFGSYLGYSVGAGHFRSPHTTEVVGGAPQHEQIGKAYVFSIDAKE ***:****:*::*******************. *******************:**** .* ENSMUSP00000099718/1-1032 LNIVYEMKGKKLGSYFGASVCAVDLNADGFSDLLVGAPMQSTIREEGRVFVYINSGMGAV ENSRNOP00000006880/1-1036 LTIVYEMKGKKLGSYFGASVCAVDLNADGFSDLLVGAPMQSTIREEGRVFVYINSGMGAV ENSP00000380227/1-1032 LNILHEMKGKKLGSYFGASVCAVDLNADGFSDLLVGAPMQSTIREEGRVFVYINSGSGAV ENSCPOP00000008508/1-1035 LSIIHEMKGKKLGSYFGASVCAVDLNADGFSDLLVGAPMHSTIREEGRVFVFINSGTNCI XP_004868219.1/1-1041 LNILYEMKGKKLGSYFGASICAVDLNADGFSDLLVGAPMHSTVREEGRVFVFINSGVGAV *.*::**************:*******************:**:********:**** ..: ENSMUSP00000099718/1-1032 MVEMERVLVGSDKYAARFGESIANLGDIDNDGFEDIAIGAPQEDDLRGAVYIYNGRVDGI ENSRNOP00000006880/1-1036 MVEMERVLVGSDKYAARFGESMANLGDIDNDGFEDIAIGAPQEDDLRGAVYIYNGRVDGI ENSP00000380227/1-1032 MNAMETNLVGSDKYAARFGESIVNLGDIDNDGFEDVAIGAPQEDDLQGAIYIYNGRADGI ENSCPOP00000008508/1-1035 FLEMETPLIGSDKYAARFGEAIVNLGDIDSDGFEDVAIGAPQEDDLRGAIYIYNGRVDGI XP_004868219.1/1-1041 MNEMETALIGSDKYAARFGESIVNLGDIDNDGFEDVAIGAPQEDELRGAIYIYNGRVDGI : ** *:***********::.******.*****:********:*:**:******.*** ENSMUSP00000099718/1-1032 SSTYSQRIEGQQISKSLRMFGQSISGQIDADNNGYVDVAVGAFQSDSAVLLRTRPVVIVE ENSRNOP00000006880/1-1036 SSTYSQRIEGRQISQSLRMFGQSISGQIDADNNGYVDVAVGAFQSDSAVLLRTRPVVIVE ENSP00000380227/1-1032 SSTFSQRIEGLQISKSLSMFGQSISGQIDADNNGYVDVAVGAFRSDSAVLLRTRPVVIVD ENSCPOP00000008508/1-1035 SSSFSQRIGGLQISESLSMFGQSISGQIDADNNGYIDIAVGAFRSDSAVLLRTRPVVIVE XP_004868219.1/1-1041 SSAFSQRIGGLQISESLSMFGQSISGQIDADNNGYIDVAVGAFRSESAVLLRTRPVVIVE **::**** * ***:** *****************:*:*****:*:*************: ENSMUSP00000099718/1-1032 ASLSHPESVNRTKFDCTENGLPSVCMHLTLCFSYKGKEVPGYIVLFYNVSLDVHRKAESP ENSRNOP00000006880/1-1036 ASLSHPESVNRTKFDCTENGLLSVCVDLKLCFSYKGKEVPGYIVLFYNVSLDVHRKAESP ENSP00000380227/1-1032 ASLSHPESVNRTKFDCVENGWPSVCIDLTLCFSYKGKEVPGYIVLFYNMSLDVNRKAESP ENSCPOP00000008508/1-1035 ASLSNPESVNRTKFDCVENGLPSVCMDLTLCFSYKGKEVPGYIVLFYNMSLDVNRKTESP XP_004868219.1/1-1041 ASLSHPESVNRTKFDCVENGAPSVCMDLKLCFSYKGKEVPGYIVLFYNMSLDVNRKAESP ****:***********.*** ***:.*.*******************:****:**:*** ENSMUSP00000099718/1-1032 SRFYFFSNGTSDVITGSIRVSSSGEKCRTHQAFMRKDVRDILTPIHVEATYHLGHHVITK ENSRNOP00000006880/1-1036 SRFYFFSNGTSDMITRSIRVSSSGEKCRTHQAFMRKDVRDILTPIQVEATYHLGHHVITK ENSP00000380227/1-1032 PRFYFSSNGTSDVITGSIQVSSREANCRTHQAFMRKDVRDILTPIQIEAAYHLGPHVISK ENSCPOP00000008508/1-1035 SRFYFSSNGTSDVITGSIQVWNRRVNCRTHQAFMRKDVRDILTPIQVEAAYHLGHHVISK XP_004868219.1/1-1041 SRFYFSSNGTSDVITGSIQVSSRRANCRTHQAFMRKDVRDILTPIQIEAAYHLGHHVISK .**** ******:** **:* . :*******************::**:**** ***:* ENSMUSP00000099718/1-1032 RNTEEFPPLQPILQQKKEKDVIRK-MINFARFCAYENCSADLQVSAKVGFLKPYENKTYL ENSRNOP00000006880/1-1036 RNTEEFPPLQPILQQKKEKDIIRK-TINFARFCAYENCSADLQVSAKVGFLKPYENKTYL ENSP00000380227/1-1032 RSTEEFPPLQPILQQKKEKDIMKK-TINFARFCAHENCSADLQVSAKIGFLKPHENKTYL ENSCPOP00000008508/1-1035 RSAEEFPPLQPILQQKKEKDLKRKHNINFARFCAHENCSADLQVSAKIGFFKPYENKTYL XP_004868219.1/1-1041 RSTEEFPPLQPILQQKKEKDMIKK-VINFARFCAHENCSADLQVSAKIGFFKPYENKTYL *.:*****************: :* ********:************:**:**:****** ENSMUSP00000099718/1-1032 AVGSMKTIMLNVSLFNAGDDAYETTLNVQLPTGLYFIKILDLEEKQINCEVTESSGIVKL ENSRNOP00000006880/1-1036 AVGSMKTIMLNVSLFNAGDDAYETTLNVQLPTGLYFIKILDLEEKQINCDVTESSGVVKL ENSP00000380227/1-1032 AVGSMKTLMLNVSLFNAGDDAYETTLHVKLPVGLYFIKILELEEKQINCEVTDNSGVVQL ENSCPOP00000008508/1-1035 AVGSMKTLMLNVSLFNAGDDAYETTLHIRLPTGLYFIKMLDLGEKQINCEVTDTSGTVKL XP_004868219.1/1-1041 AVGSTKTLMLNVSLFNAGDDAYETTLYIRLPTGLYFIKILDLEEKQINCEVTDNSGTVKL **** **:****************** ::**.******:*:* ******:**:.** *:* ENSMUSP00000099718/1-1032 ACSLGYIYVDRLSRIDISFLLDVSSLSRAHEDLSISVHASCENEGELDQVRDNRVTLTIP ENSRNOP00000006880/1-1036 ACSLGYIYVDRLSRIDISFLLDVSSLSRAHEDLSINVHASCENEGKLDQVKDNRVTLVIP ENSP00000380227/1-1032 DCSIGYIYVDHLSRIDISFLLDVSSLSRAEEDLSITVHATCENEEEMDNLKHSRVTVAIP ENSCPOP00000008508/1-1035 DCTLGYIYVDHLSRMDVSFLLDVSSLRRADEDLNITVLASCENEREMNKLMDNKVTVTIP XP_004868219.1/1-1041 HCTLGYIYVDYLSRTDVSFLLDVSSLRRAEEDLNIMVLASCANEGEMDKLQDNKVIVAIP *::****** *** *:********* **.***.* * *:* ** ::::: ..:* :.** ENSMUSP00000099718/1-1032 LRYEVMLTVHGLVNPTSFVYGSSEENEPETCMAEKLNLTFHVINTGISMAPNVSVKIMVP ENSRNOP00000006880/1-1036 LRYEVMLAVHGFVTPTSFVYGSSEENEPEMCMAEKLNLTFHVINTGISMAPNVSVKIMVP ENSP00000380227/1-1032 LKYEVKLTVHGFVNPTSFVYGSNDENEPETCMVEKMNLTFHVINTGNSMAPNVSVEIMVP ENSCPOP00000008508/1-1035 LRYEVMLAVHGFVNPTSFMYGSTEDSELESCVSEKMNFTFHVINTGISMAPNVSVEIMVP XP_004868219.1/1-1041 LRYEVMLAVHGFVNPASFVYGSSEDNEPETCMTEKMNFTFHVINMGISMAPNVSVEIMIP *:*** *:***:*.*:**:***.::.* * *: **:*:****** * ********:**:* ENSMUSP00000099718/1-1032 NSFLPQDDKLFNVLDVQTTTGQCHFKHYGRECTFAQQKGIAGTLTDIVKFLSKTDKRLLY ENSRNOP00000006880/1-1036 NSFLPRNDKLFNVLDVQATMGQCQFEHYGRECALAQQKGIAGTLTDLVKFLSKTDKRLLY ENSP00000380227/1-1032 NSFSPQTDKLFNILDVQTTTGECHFENYQRVCALEQQKSAMQTLKGIVRFLSKTDKRLLY ENSCPOP00000008508/1-1035 NAFVPQTDKLFNVLDVQTTTGQCKFENYQRECVSGQKRDAMETVRSIFKFLSKTDKRVLY XP_004868219.1/1-1041 NSFLPRTDKLFNILDVQTTTGQCKFENYPRECATEQQRYAVETLKGILTFLSKTDRRVLY *:* *: *****:****:* *:*:*::* * *. *:: *: .:. ******:*:** ENSMUSP00000099718/1-1032 CMKADQHCLDFLCNFGKMESGKEASVHIQLEGRPSILEMDETSSLKFEIKATAFPEPHPK ENSRNOP00000006880/1-1036 CMKADRHCLDFLCNFGKMESGKEASVHIQLEGRPSILEMDETSSLKFEIKATAFPEPHPK ENSP00000380227/1-1032 CIKADPHCLNFLCNFGKMESGKEASVHIQLEGRPSILEMDETSALKFEIRATGFPEPNPR ENSCPOP00000008508/1-1035 CMKTDSYCLNFLCNFGKMESGKEASVHIQLEGRPSVLEMDDTSALKFEIRATAFPEPHPK XP_004868219.1/1-1041 CMKADPYCLSFLCNFGKMESGKEASVHIQLEGRPSILEMDDTSALKFEIRATAFPEPHPR *:*:* :**.*************************:****:**:*****:**.****:*: ENSMUSP00000099718/1-1032 VIELNKDENVAHVFLEGLHHQRPKRHFTIIIITISLLLGLIVLLLISCVMWKAGFFKRQY ENSRNOP00000006880/1-1036 VIELNKDENIAHVYLEGLHHQRPKRHFTIVIVTISLLLGLIVLLLISCVMWKAGFFKRQY ENSP00000380227/1-1032 VIELNKDENVAHVLLEGLHHQRPKRYFTIVIISSSLLLGLIVLLLISYVMWKAGFFKRQY ENSCPOP00000008508/1-1035 VIELNEDENIAHVLLEGLHHQKPKRRVTIVIISSSLLLGLAVLFVISCVMWKAGFFKRQY XP_004868219.1/1-1041 VIELNKDENAAHVLLEGLHHQKPKRHFTIVIISSSLLLGFVVLFLISCVMWKAGFFKRQY *****:*** *** *******:*** .**:*:: *****: **::** ************ ENSMUSP00000099718/1-1032 KSILQEENRRDSWSYVNSKSNDD-- ENSRNOP00000006880/1-1036 KSILQEENRRDSWSYVNSKSNDD-- ENSP00000380227/1-1032 KSILQEENRRDSWSYINSKSNDD-- ENSCPOP00000008508/1-1035 KSILQEEN-RDSWSYVNSKNNDD-- XP_004868219.1/1-1041 KSILQEEN-RDSWSYVNSKSNDNDD ******** ******:***.**: