CLUSTAL W(1.81) multiple sequence alignment ENSRNOP00000065604/1-971 ----------------------------------------MDLNSASSVVLQVLTQATSQ ENSMUSP00000079667/1-975 ----------------------------------------MDLNSASSVVLQVLTQATSQ ENSCPOP00000008452/1-974 ----------------------------------------MDLNSASTVVLQVLTQATSQ ENSP00000386992/1-1015 MVQPIIHLGYVVYSLLYLGYKPVQHVTALNTVSSCHKMVSMDLNSASTVVLQVLTQATSQ XP_004862940.1/1-975 ----------------------------------------MDLNSASTVVLQVLTQATSQ *******:************ ENSRNOP00000065604/1-971 DTAVLKPAEEQLKQWETQPGFYSVLLNIFTNHTLDINVRWLAVLYFKHGIDRYWRRVAPH ENSMUSP00000079667/1-975 DTAVLKPAEEQLKQWETQPGFYSVLLNIFTNHTLDINVRWLAVLYFKHGIDRYWRRVAPH ENSCPOP00000008452/1-974 DTAILKPAEEQLKQWETQPGFYSVLLNIFTNHSLDINVRWLAVLYFKHGIDRYWRRVAPH ENSP00000386992/1-1015 DTAVLKPAEEQLKQWETQPGFYSVLLNIFTNHTLDINVRWLAVLYFKHGIDRYWRRVAPH XP_004862940.1/1-975 DTAVLKPAEEQLKQWETQPGFYSVLLNIFTNHSLDINVRWLAVLYFKHGIDRYWRRVAPH ***:****************************:*************************** ENSRNOP00000065604/1-971 ALSEEEKSTLRAGLITNFNEPINQIATQIAVLIAKVARLDCPRQWPELIPTLVESVKVQD ENSMUSP00000079667/1-975 ALSEEEKSTLRAGLITNFNEPINQIATQIAVLIAKVARLDCPRQWPELIPTLVESVKVQD ENSCPOP00000008452/1-974 ALSEEEKSTLRAGLITNFNEPINQIATQIAVLIAKVARLDCPRQWPELIPTLIESVKVQD ENSP00000386992/1-1015 ALSEEEKTTLRAGLITNFNEPINQIATQIAVLIAKVARLDCPRQWPELIPTLIESVKVQD XP_004862940.1/1-975 ALSEEEKSTLRAGLITNFNEPINQIATQIAVLIAKVARLDCPRQWPELIPTLIESVKVQD *******:********************************************:******* ENSRNOP00000065604/1-971 DLRQHRALLTFYHVTKTLASKRLAADRKLFYDLASGIYNFACSLWNHHTDTFLQQVSSGN ENSMUSP00000079667/1-975 DLRQHRALLTFYHVTKTLASKRLAADRKLFYDLASGIYNFACSLWNHHTDTFLQHVSSGN ENSCPOP00000008452/1-974 DLRQHRALLTFYHVTKTLASKRLAADRKLFYDLASGIYTFACSLWNHHTDTFLQQVSSGN ENSP00000386992/1-1015 DLRQHRALLTFYHVTKTLASKRLAADRKLFYDLASGIYNFACSLWNHHTDTFLQEVSSGN XP_004862940.1/1-975 DLRQHRALLTFYHVTKTLASKRLAADRKLFYDLASGIYTFACSLWNHHTDTFLQQVSSGN **************************************.***************.***** ENSRNOP00000065604/1-971 EAAVLSSLERTLLSLKVLRKLTVNGFVEPHKNMEVMGFLHGIFERLKQFLECSRSIGTDN ENSMUSP00000079667/1-975 EAAVLSSLERTLLSLKVLRKLTVNGFVEPHKNMEVMGFLHGIFERLKQFLECSRSIGTDN ENSCPOP00000008452/1-974 EVAVLSSLERTLLSLKVLRKLTVNGFVEPHKNMEVMVSNRSNFNAYNVFL-IGRNIGVDN ENSP00000386992/1-1015 EAAILSSLERTLLSLKVLRKLTVNGFVEPHKNMEVMGFLHGIFERLKQFLECSRSIGTDN XP_004862940.1/1-975 EVAVLSSLERTLLSLKVLRKLTVNGFVEPHKNMEVMGFLHGIFERLKQFLECSRNIGTDN *.*:******************************** :. *: : ** .*.**.** ENSRNOP00000065604/1-971 VCRDRLEKTIILFTKVLLDFLDQHPISFTPLIQRSLEFSVSYVFTEVGEGVTFERFIVQC ENSMUSP00000079667/1-975 VCRDRLEKTIILFTKVLLDFLDQHPISFTPLIQRSLEFSVSYVFTEVGEGVTFERFIVQC ENSCPOP00000008452/1-974 VCRDRLEKTIILFTKVLLDFLDQHPFSFIPLIQRSLEFSVSYVFTEVGEGITFERFIVQC ENSP00000386992/1-1015 VCRDRLEKTIILFTKVLLDFLDQHPFSFTPLIQRSLEFSVSYVFTEVGEGVTFERFIVQC XP_004862940.1/1-975 VCRDRLEKTIILFTKVLLDFLDQHPFSFTPLIQRSLEFSVSYVFTEVGEGVTFERFIVQC *************************:** *********************:********* ENSRNOP00000065604/1-971 MNLIKMIVKNYAYKPSKNFEDSSPETLEAHKIKMAFFTYPTLTEICRRLVSHYFLLTEEE ENSMUSP00000079667/1-975 MNLIKMIVKNYAYKPSKNFEDSSPETLEAHKIKMAFFTYPTLTEICRRLVSHYFLLTEEE ENSCPOP00000008452/1-974 MNLIKMIVKNYAYKPSKNFEDSSPETLEAHKIKMAFFTYPTLTEICRRLVSHYFLLTEEE ENSP00000386992/1-1015 MNLIKMIVKNYAYKPSKNFEDSSPETLEAHKIKMAFFTYPTLTEICRRLVSHYFLLTEEE XP_004862940.1/1-975 MNLIKMIVKNYAYKPSKNFEDSSPETLEAHKIKMAFFTYPTLTEICRRLVSHYFLLTEEE ************************************************************ ENSRNOP00000065604/1-971 LTMWEEDPEGFTVEETGGDSWKYSLRPCTEVLFIDIFHEYNQTLTPVLLEMMQTLQGTSQ ENSMUSP00000079667/1-975 LTMWEEDPEGFTVEETGGDSWKYSLRPCTEVLFIDIFHEYNQTLTPVLLEMMQTLEGPTN ENSCPOP00000008452/1-974 LTMWEEDPEGFTVEETGGDSWKYSLRPCTEVLFIDIFHEYNQTLTPVLLEMMQTLQGPTN ENSP00000386992/1-1015 LTMWEEDPEGFTVEETGGDSWKYSLRPCTEVLFIDIFHEYNQTLTPVLLEMMQTLQGPTN XP_004862940.1/1-975 LTMWEEDPEGFTVEETGGDSWKYSLRPCTEVLFIDIFHEYNQTLTPVLLEMMQTLQGPTN *******************************************************:*.:: ENSRNOP00000065604/1-971 VTGFNFVLF--SVYNAVGLAAFELFDSVDFDQWFKTQLLPELQVSHNR-QPLRRRVIWLI ENSMUSP00000079667/1-975 VEDMNALLIKDAVYNAVGLAAFELFDSVDFDQWFKTQLLPELQVSHNRYKPLRRRVIWLI ENSCPOP00000008452/1-974 VEDMNALLIKDAVYNAVGLAAYELFDSVDFDQWFKNQLLPELQVIHNRYKPLRRRVIWLI ENSP00000386992/1-1015 VEDMNALLIKDAVYNAVGLAAYELFDSVDFDQWFKNQLLPELQVIHNRYKPLRRRVIWLI XP_004862940.1/1-975 VEDMNALLIKDAVYNAVGLAAYELFDSVDFDQWFKNQLLPELQVIHNRYKPLRRRVIWLI * .:* :*: :*********:*************.******** *** :********** ENSRNOP00000065604/1-971 GQWISVKFKSDLRPRLYEAICNLLQDQDLVVRIETATTLKLALD---FWTDQFLPYLETM ENSMUSP00000079667/1-975 GQWISVKFKSDLRPMLYEAICNLLQDQDLVVRIETATTLKLTVDDFEFRTDQFLPYLETM ENSCPOP00000008452/1-974 GQWISVKFKSDLRPMLYEAICNLLQDQDLVVRIETATTLKLTVDDFEFRTDQFLPYLETM ENSP00000386992/1-1015 GQWISVKFKSDLRPMLYEAICNLLQDQDLVVRIETATTLKLTVDDFEFRTDQFLPYLETM XP_004862940.1/1-975 GQWISVKFKSDLRPMLYEAICNLLQDQDLVVRIETATTLKLTVDDFEFRTDQFLPYLETM ************** **************************::* * *********** ENSRNOP00000065604/1-971 FTLLFQLLQQVTECDTKMHVLHVLSCVIERVNIQVMFILKKLLTYMFSFHLCTDTYSLGM ENSMUSP00000079667/1-975 FTLLFQLLQQVTECDTKMHVLHVLSCVIERVNVQIRPYVGCLVQYLPLLWKQSEEHNM-L ENSCPOP00000008452/1-974 FTLLFQLLQQVTECDTKMHVLHVLSCVIERVNMQIRPYVGCLVQYLPLLWKQSEEHNM-L ENSP00000386992/1-1015 FTLLFQLLQQVTECDTKMHVLHVLSCVIERVNMQIRPYVGCLVQYLPLLWKQSEEHNM-L XP_004862940.1/1-975 FTLLFQLLQQVTECDTKMHVLHVLSCVIERVNMQIRPYVGCLVQYLPLLWKQSEEHNM-L ********************************:*: : *: *: : :: :.: : ENSRNOP00000065604/1-971 RGGILEFLI-INRGLGADSKNLYPFLLPVIQLSTDVSQPPHVYLLEDGLELWLVTLENSP ENSMUSP00000079667/1-975 RCAILTTLIHLVQGLGADSKNLYPFLLPVIQLSTDVSQPPHVYLLEDGLELWLVTLENSP ENSCPOP00000008452/1-974 RCAILTTLIHLVQGLGADSKNLYPFLLPVIQLSTDVSQPPHVYLLEDGLELWLVTLENSP ENSP00000386992/1-1015 RCAILTTLIHLVQGLGADSKNLYPFLLPVIQLSTDVSQPPHVYLLEDGLELWLVTLENSP XP_004862940.1/1-975 RCAILTTLIHLVQGLGADSKNLYPFLLPVIQLSTDVSQPPHVYLLEDGLELWLVTLENSP * .** ** : :*********************************************** ENSRNOP00000065604/1-971 CVTPELLRIFQNMSPLLELPSSCLANELSSENLRTCFKIINGYIFLSSTEFLQTYAAGLC ENSMUSP00000079667/1-975 CVTPELLRIFQNMSPLL---------ELSSENLRTCFKIINGYIFLSSTEFLQTYAAGLC ENSCPOP00000008452/1-974 CITPELLRVFQNMSPLL---------ELSSENLRTCFKIINGYIFLSSTEFLQTYAAGLC ENSP00000386992/1-1015 CITPELLRIFQNMSPLL---------ELSSENLRTCFKIINGYIFLSSTEFLQTYAVGLC XP_004862940.1/1-975 CITPELLRVFQNMSALL---------ELSSENLRTCFKIINSYIFLSSTEFLQTYAVGLC *:******:*****.** ***************.**************.*** ENSRNOP00000065604/1-971 QSFYELLPEITTEGQVQVLKVVENTLKVNPVLGPQMFQRILPYVFRGVIEGERYPVVMSI ENSMUSP00000079667/1-975 QSFYELLPEITTEGQVQVLKVVENALKVNPVLGPQMFQRILPCVFRGVIEGERYPVVMSI ENSCPOP00000008452/1-974 QSFCELLKEITTEGQVQVLEVVENALKVNPVLGPQMFQPILPYVFKGIIEGERYPVVMST ENSP00000386992/1-1015 QSFCELLKEITTEGQVQVLKVVENALKVNPILGPQMFQPILPYVFKGIIEGERYPVVMST XP_004862940.1/1-975 QSFCELLKEITTEGQVQVLKVVENALKVNPVLGPQMFQPILPCVFRGIIEGERYPVVMST *** *** ***********:****:*****:******* *** **:*:*********** ENSRNOP00000065604/1-971 YLAVMGRVLLQNASFFSSLLNEMGHEFNQEMDQLLGNVIEMWVDRMDNITQPERKKLSAL ENSMUSP00000079667/1-975 YLAVMGRVLLQNTSFFSSLLNEMGHEFNQEMDQLLGNVIEMWVDRMDNITQPERKKLSAL ENSCPOP00000008452/1-974 YLGVMGRVLLQNASFFSSLLNEMAHKFNQEMDQLLGNMIEMWVDRMDNITQPERRKLSAL ENSP00000386992/1-1015 YLGVMGRVLLQNTSFFSSLLNEMAHKFNQEMDQLLGNMIEMWVDRMDNITQPERRKLSAL XP_004862940.1/1-975 YLGVMGRVLLQNASFFSSLLNEMAHKFNQEMDQLLGNMIEMWVDRMDNITQPERRKLSAL **.*********:**********.*:***********:****************:***** ENSRNOP00000065604/1-971 ALLSLLPSDNRSLTDPFKGKKNQSTVAIKSKQNQNS-------CMLMSHHEEPKVTEDEE ENSMUSP00000079667/1-975 ALLSLLPSDNSVIQDKFCGIINISVEALHDVMTEDPETRTYKDCMLMSQHEEPKVTEDEE ENSCPOP00000008452/1-974 ALLSLLPSENSVIQDKFCGIINISVEGLHDVMTEDPETGTYKDCMLMSHLEEPKVTEDEE ENSP00000386992/1-1015 ALLSLLPSDNSVIQDKFCGIINISVEGLHDVMTEDPETGTYKDCMLMSHLEEPKVTEDEE XP_004862940.1/1-975 ALLSLLPSDNSVIQDKFCGIINISVEGLHDVMTEDPETRTYKDCMLMSHLEEPKVTEDEE ********:* : * * * * *. .::. .::. *****: ********** ENSRNOP00000065604/1-971 PPTEQDKRKKMLALKDPVHTVSLQQFIYEKLKAQQEILGEQGFQSLMETVDTEIVTQLQE ENSMUSP00000079667/1-975 PPTEQDKRKKMLALKDPVHTVSLQQFIYEKLKAQQEILGEQGFQSLMETVDTEIVTQLQE ENSCPOP00000008452/1-974 PPTEQDKRKKMLALKDPVHTVSLQQFIYEKLKAQQEVLGEQGFQSLMETVDTEIVTQLQE ENSP00000386992/1-1015 PPTEQDKRKKMLALKDPVHTVSLQQFIYEKLKAQQEMLGEQGFQSLMETVDTEIVTQLQE XP_004862940.1/1-975 PLTEQDKRKKMLALKDPVHMVSLQQFVYEKLKAQQEVLGEQGFQSLMETVDTEIVTQLQE * ***************** ******:*********:*********************** ENSRNOP00000065604/1-971 FLQGF ENSMUSP00000079667/1-975 FLQGF ENSCPOP00000008452/1-974 FLQGF ENSP00000386992/1-1015 FLQGF XP_004862940.1/1-975 FLQGF *****