CLUSTAL W(1.81) multiple sequence alignment ENSP00000444797/1-801 ---------------------------------------------------------MAS ENSMUSP00000106394/1-771 MPHPTWRPHRVHPGASGSTSRRAPQPRPLPGSLWSCGRAGFEHPYAGRLGDCEAAAPAAS ENSRNOP00000001479/1-707 ------------------------------------------------------------ ENSCPOP00000008123/1-703 ------------------------------------------------------------ XP_004840442.1/1-727 ---------------------------------------------MTNTDTAAPESNTDT ENSP00000444797/1-801 SGEDISNDDDDMHPAAAGMADGVHLLGFSDEILLHILSHVPSTDLILNVRRTCRKLAALC ENSMUSP00000106394/1-771 SGEDMSSEEE----AAAEAAGDTHLLGFSDEILLHILSHVPSTDLVLSVRRTCRKLAALC ENSRNOP00000001479/1-707 ----MSNDDE----AAAEAAGDTHLLGFSDEILLHILSHVPSTDLVLNVRRTCRKLAALC ENSCPOP00000008123/1-703 ----TMAPD-----ATAETGGSVHLLGFSDEILLHILSHVPSTDLVVNVRRVCRKLAALS XP_004840442.1/1-727 VGPDTAAPDTAAPAAAAEVAGSAHLLGFSDEILLHILSHVPSTDLVVNVRHVCRKLAALS : *:* ....**********************::.**:.*******. ENSP00000444797/1-801 LDKSLIHTVLLQKDYQASEDKVRQLVKEIGREIQQLSMAGCYWLPGSTVEHVARCRSLVK ENSMUSP00000106394/1-771 LDKSLVHTVLLQKDYQASEEKVKQLVKEIGREIQQLNMAGCYWLSGSTIEHVARCHSLVK ENSRNOP00000001479/1-707 LDKSLVHTVLLQKDYQASEEKVKQLVKEIGREIQQLNMAGCYWLPGSTIEHVARCHSLVK ENSCPOP00000008123/1-703 LDKSLVHTVLLQKDYQASEDKVKQLVKVIGREIQQLSMAGCYWLSGSTIEHVARCRGLVK XP_004840442.1/1-727 LDKSLVHTVLLQKDYQASEDKVKQLVKVIGREIQQLSMAGCYWLSGVTIEHVARCHSLVK *****:*************:**:**** ********.*******.* *:******:.*** ENSP00000444797/1-801 VNLSGCHLTSLRLSKMLSALQHLRSLAIDVSPGFDASQLSSECKATLSRVRELKQTLFTP ENSMUSP00000106394/1-771 VNLSGCHLTSLRLSKVLSALQHLRSLAIDVSPGFDASQLSSECKATLSRVQELKQTLFTP ENSRNOP00000001479/1-707 VNLSGCHLTSLRLSRVLSCLQRLRSLAIDVSPGFDASQLSSECKATLSRVQELKQTLFTP ENSCPOP00000008123/1-703 MNLSGCHLTSLRLSKVLSALQQLRSLAIDVSPGFDASQLSSECRATLSRVRELKQTLFTP XP_004840442.1/1-727 VNLSGCHLTSLRLSKVLSALQQLRSLALDVIPGFDASQLSSECRATLSRVQELKQTLFTP :*************::**.**:*****:** ************:******:********* ENSP00000444797/1-801 SYGVVPCCTSLEKLLLYFEILDRTREGAILSGQLMVGQSNVPHYQNLRVFYARLAPGYIN ENSMUSP00000106394/1-771 SYGVVPCCASLQKLLLYFEILDRTREGAVLSGQLMVGQSNVPHYQNLRVFYARLAPGYIN ENSRNOP00000001479/1-707 SYGVVPCCASLQKLLLYFEILDRTREGAVLSGQLMVGQSNVPHYQNLRVFYARLAPGYIN ENSCPOP00000008123/1-703 SYGVVPCCASLQKLLLYFEILDRTREGAVLSGQLMVGQSNVPHYQNLRIFYARLAPGYIN XP_004840442.1/1-727 SYGVVPCCASLQKLLLYFEILDRTREGAVLSGQLMVGQSNVPHYQNLRVFYARLAPGYIN ********:**:****************:*******************:*********** ENSP00000444797/1-801 QEVVRLYLAVLSDRTPQNLHAFLISVPGSFAESGATKNLLDSMARNVVLDALQLPKSWLN ENSMUSP00000106394/1-771 QEVVRLYLAVLSDRTPENLHAFLISVPGSFAESGATKNLLDSMARNVALDALQLPKSWLN ENSRNOP00000001479/1-707 QEVVRLYLAVLSDRTPENLHAFLISVPGSFAESGATKNLLDSMARNVALDALQLPKSWLN ENSCPOP00000008123/1-703 QEVVRLYLAVLSDRTPENLHAFLISVPGSFAESGATKNLLESMARNVALDALQLPKSWLN XP_004840442.1/1-727 QEVVRLYLAVLSDRTPENLHAFLISVPGSFAESGATKNLLESMARNVALDALQLPKSWLN ****************:***********************:******.************ ENSP00000444797/1-801 GSSLLQHMKFNNPFYFSFSRCTLSGGHLIQQVINGGKDLRSLASLNLSGCVHCLSPDSLL ENSMUSP00000106394/1-771 GSTLLQHMKFNNPFYFSFSRCTLSGGHLIQRLINGGKDLRSLASLNLSGCVHCLSADSLL ENSRNOP00000001479/1-707 GSTLLQHMKFNNPFYFSFSRCTLSGGHLIQRLINGGKDLRSLASLNLSGCVHCLSADSLL ENSCPOP00000008123/1-703 GSSLLQHMKFNNPFYFSFSRCTLSGGHLIQRVINGGKDLRSLASLNLSGCVHCLLPDSLL XP_004840442.1/1-727 GSSLLQHIKFNNPFYFSFSRCTLSGGHLIQRVINDGKDLRSLASLNLSGCVHCLSPDSLL **:****:**********************::**.******************* .**** ENSP00000444797/1-801 RKAEDDIDSSILETLVASCCNLRHLNLSAAHHHSSEGLGRHLCQLLARLRHLRSLSLPVC ENSMUSP00000106394/1-771 RKAEDDIDSSILETLVESCCNLHHLNLSAAHHHSSDGLGRHLCQLLARLCHLRSLSLPVC ENSRNOP00000001479/1-707 RKAEDDIDSSILETLVESCCNLHHLNLSAAHHHSSDGLGRHLCQLLARLCHLRSLSLPVC ENSCPOP00000008123/1-703 HKAEDDIDSSILETLVASCCNLRHLNLSAAHHHSSEGLGRHLCHLLARLRHLRSLSLPVC XP_004840442.1/1-727 RKAEDDIDSSILETLVASCCNLRHLNLSAAHHHSSEGLGRHLCHLLARLCHLRSLSLPVC :*************** *****:************:*******:***** ********** ENSP00000444797/1-801 SVADSAPRADRAPAQPAMHAVPRGFGKKVRVGVQSCPSPFSGQACPQPSSVFWSLLKNLP ENSMUSP00000106394/1-771 SVADSAPRPDRAPAPPAMHAVPRGFGKKVRIGVQTCPNPFVGQSAPQPASVFWSLLKKLP ENSRNOP00000001479/1-707 SVADSAPRPDRAPAPPAMHAVPRGFGKKVRIGVQTCPNPFVGQSAPQPASVFWSLLKKLP ENSCPOP00000008123/1-703 SVADSAPRADRAPAQPAMHAVPRGFGKKVRIGVQTCSGPFAGH---QPSSAFWSLLKNLP XP_004840442.1/1-727 SVADSAPRADRVPAQPAMHAVPRGFGKRVRIGVQTCPGPFAGQ---QPSSAFWSLLKNLP ********.**.** ************:**:***:*..** *: **:*.******:** ENSP00000444797/1-801 FLEHLELIGSNFSSAMPRNEPAIRNSLPPCSRAQSVGDSEVAAIGQLAFLRHLTLAQLPS ENSMUSP00000106394/1-771 FLEHLELIGSNFSSAMPRNEPAIRNSLPPCSRAQNVGDSEVAAIGQLTFLRHLTLAQLPG ENSRNOP00000001479/1-707 FLEHLELIGSNFSSAMPRNEPAIRNSLPPCSRAQNVGDSEVAAIGQLTFLRHLTLAQLPG ENSCPOP00000008123/1-703 FLEHLELIGSNFSSAMPRNEPAIRNSLPPCSRAQNVGDSEVAAIGQLAFLQHLTLAQLPG XP_004840442.1/1-727 FLEHLELIGSNFSSAMPRNEPAIRNSLPPCSRAQNVGDSEVAAIGQLAFLQHLTLAQLPG **********************************.************:**:********. ENSP00000444797/1-801 VLTGSGLVNIGLQCQQLRSLSLANLGMMGKVVYMPALSDMLKHCKRLRDLRLEQPYFSAN ENSMUSP00000106394/1-771 MLTGSGLVSIGLQCQHLQSLSLANLGMMGKVVYMPALADMLKHCKRLKDLRLEQPYFNAN ENSRNOP00000001479/1-707 MLTGSGLVSIGLQCQQLQSLSLANLGMMGKVVYMPALADMLKHCKRLKDLRLEQPYFNAN ENSCPOP00000008123/1-703 ILTGSGLLSIGLQCQQLQSLSLANLGMMGKVVYMPALSDMLKHCRRLKDLRLEQPYFNAN XP_004840442.1/1-727 ILTGSGLVSIGLQCQQLQSLSLANLGMMGKVVYVPALSDMLKHCRQLKDLRLEQPYFNAN :******:.******:*:***************:***:******::*:*********.** ENSP00000444797/1-801 AQFFQALSQCPSLQRLCLVSRSGTLQPDAVLAFMARCLQVVMCHLFTGESLATCKSLQQS ENSMUSP00000106394/1-771 AQFFQALGQCSSLQRLCLVSRSGTLQPDAVLAFMARCLQVVMCHMFTGESLTTCKSLQQS ENSRNOP00000001479/1-707 AQFFQALGQCSSLQRLCLVSRSGTLQPDAVLAFMARCLQVVMCHMFTGESLTTCKSLQQS ENSCPOP00000008123/1-703 AQFFQALSQCASLQRLCLVSRSGTLQPDAVLAFMARCLHLVVCHMFTGESLTTCKSLQQS XP_004840442.1/1-727 AQFFQALSQCASLQRLCLVSRSGTLQPDAVLAFMARCLHVVMCHMFTGESLATCKSLQQS *******.**.***************************::*:**:******:******** ENSP00000444797/1-801 LLRRWGEVTGRRPQLFTELREEPSARTSRATGRRQPCLPDSGVVCCPCGRPLAVSGIILV ENSMUSP00000106394/1-771 LLRSF---QAERPAL--------------------------NVVIF----PLLHEGL--- ENSRNOP00000001479/1-707 LLRSF---QAERPAL--------------------------NVVIF----PLLHEGL--- ENSCPOP00000008123/1-703 LLRSF---QAERPAL--------------------------NVVIF----PLLHEGL--- XP_004840442.1/1-727 LLRSF---QAERPAL--------------------------NVVIF----PLLHEGL--- *** : ..** * .** ** .*: ENSP00000444797/1-801 GVSPSLVVKTTCVYRVLFKNLDYASIFFLVCLFETESHSVVQAGVQWRDLSSLQPLLSGL ENSMUSP00000106394/1-771 ---------TDVIRDVPMLHLDEITLF-----------------------------KSRV ENSRNOP00000001479/1-707 ---------TDVIRDVPMVHLDEITLF-----------------------------KSRV ENSCPOP00000008123/1-703 ---------TDVIRDVPMVHLDEITLF-----------------------------KSRV XP_004840442.1/1-727 ---------TDVIRDVPMVHLDEITLF-----------------------------KSRV * : * : :** ::* * : ENSP00000444797/1-801 QPQPPEQLGLQVCTTIPG ENSMUSP00000106394/1-771 AEEPPNLWW--------- ENSRNOP00000001479/1-707 AEEPPNLWW--------- ENSCPOP00000008123/1-703 AEEPPNLWW--------- XP_004840442.1/1-727 AEEPPNLWW--------- :**: