CLUSTAL W(1.81) multiple sequence alignment ENSP00000351327/1-854 MMAYSDTTMMSDDIDWLRSHRGVCKVDLYNPEGQQDQDRKVICFVDVSTLNVEDKDYKDA ENSMUSP00000050962/1-849 MIAYCGTTTMSDDIDWLHSRRGVCKVDLYSPKGQQDQDRKVICFVDVSTLNVEDKDSKGA ENSRNOP00000003939/1-729 MIAYCGTTKMSDDIDWLHSRRGVCKVDLYSPKGQQDQDRKVICFVDVSTLNVED-DSKGA ENSCPOP00000008074/1-804 -----------------------------------------ICFVDVSTLNAEDKDSKGA XP_004872068.1/1-841 ------MARMMSDIDWLHSCRGVCKVDLYSPIRQQDQERKVICFVDVSNLNAEDKDSKGA *******.**.** * *.* ENSP00000351327/1-854 ASSSSEGNLNLGSLEEKEIIVIKDTEKKDQSKTEGSVCLFKQAPSDPVSVLNWLLSDLQK ENSMUSP00000050962/1-849 AGSRSEGELNLETLEEKEIIVIKDTEKQDQSKTEGSVCLFKQAPSDPISVLNWLLNDLQK ENSRNOP00000003939/1-729 AGPRSEGELNLENLEEKEIIVIKDTEKQDQSKTEGSVCLFKQAPSDPISVLNWLLNDLQK ENSCPOP00000008074/1-804 AGSSSELDFNLQTLEDKEIIVIKDTEKQDQSKMEGSVCLFKQAPFDPLIVLNWLLNDLQK XP_004872068.1/1-841 TGSSSEFNFNLQTLEDKEIVVIKDTEKKDQSKIEGSVCLFKQAPFDPLVVLHWLLIDLQK :.. ** ::** .**:***:*******:**** *********** **: **:*** **** ENSP00000351327/1-854 YALGFQHALSPSTSTCKHKVGDTEGEYHRASSENCYSVYADQVNIDYLMNRPQNLRLEMT ENSMUSP00000050962/1-849 YALGFQHALSPSASSCKHKVGDLEGDYSKIPSENCYSVYADQVNFDYLNKGPQNLRLEMA ENSRNOP00000003939/1-729 YALGFQHALSPSASSCKHKVGDLEGDYHKIPSENCYSVYADQVNLDYLNKGPQNLRLEMA ENSCPOP00000008074/1-804 YALGFQHALSPSTSSCKHKVGDLD-NYNK--SGNCYSVYADKLSIDHMAKGPQRLRLEMT XP_004872068.1/1-841 HALGFQHALSPSASSCKHKAGDID-DYHK--TGNCYSVYADKLSIDHTAKGPQCLHLEMT :***********:*:****.** : :* : : ********::.:*: : ** *:***: ENSP00000351327/1-854 AAKNTNNNQSPSAPPAKPPSTQRAVISPDGECSIDDLSFYVNRLSSLVIQMAHKEIKEKL ENSMUSP00000050962/1-849 ASKNTNNNQSPSNPATKSPSNQRSVATPEGECSMDDLSFYVNRLSSLVIQMARKEIKDKL ENSRNOP00000003939/1-729 ASKNTNNNQSPSNPATKSPSNQRSVATPDGECSMDDLSYYVNRLSSLVIQMARKEIKDKL ENSCPOP00000008074/1-804 AAKNTNNNQSPSTPVVKSSNTQREVKSPDGECSMDDLSYYVNRLSSLVIQMARKEIKDKL XP_004872068.1/1-841 ATKNTNNNQSPSTPVVKSSNTQKEVKSPDGECSMDDLSYYVNQLSSLVIQMACKEIKEKL *:********** * .*....*: * :*:****:****:***:********* ****:** ENSP00000351327/1-854 EGKSKCLHHSICPSPGNKERISPRTPASKIASEMAYEAVELTAAEMRGTGEESREGGQKS ENSMUSP00000050962/1-849 EGGSKCLHHSMY-TSGDKGKTSPRSAVSKIASEMAHEAVELTSSEMRGNGEDCRD-GRKT ENSRNOP00000003939/1-729 EGGNKCLHHSMY-TSGEKGKTSPRSAVSKIASEMAHEAVELTSSEMRGNGEEGRD-GRKT ENSCPOP00000008074/1-804 ENGSKCLHHSVYLPPGDKGKSSPRSPLSKIASEMAHEAVELTSSEMRGTGEENKEGGQKT XP_004872068.1/1-841 ESGSKGLHHSVYQPTGEKGKNSPHSPLSKIASEMAHEEVELTSSEMCGTGEENQEGGQKT *. .* ****: ..*:* : **::. ********:* ****::** *.**: :: *:*: ENSP00000351327/1-854 FLYSELSNKSKSGDK-QMSQRESKEFADSISKGLMVYANQVASDMMVSLMKTLKVHSSGK ENSMUSP00000050962/1-849 FLYSEMCNKNKCGEKQQMCPKDSKEFADSISKGLMVYANQVASDMMVSVMKTLKVHSCGK ENSRNOP00000003939/1-729 FLYSELSNKNKCGEKQQMCPKDSKEFADSISKGLMVYANQVASDMMVSVMKTLKVHSCGK ENSCPOP00000008074/1-804 FMYSELSNKSKCGEK-QMFQKDSKEFADSISKGLMVYANQVASDMMVSVMKTLKVHSSGK XP_004872068.1/1-841 FLYSELSNKSKCGEK-QMFQRDSKEFADSISKGLMVYANQEASDMIVSVMKTLKVHSSGK *:***:.**.*.*:* ** ::****************** ****:**:********.** ENSP00000351327/1-854 PIPASVVLKRVLLRHTKEIVSDLIDSCMKNLHNITGVLMTDSDFVSAVKRNLFNQWKQNA ENSMUSP00000050962/1-849 PIPACVVLKRVLLKHTKEIVSDLIDSCMKNLHNITGVLMTDSDFVSAVKRNLFNHGKQNA ENSRNOP00000003939/1-729 PIPACVVLKRVLLKHTKEIVSDLIDSCMKNLHNITGVLMTDSDFVSAVKRNLFNHGKQNA ENSCPOP00000008074/1-804 PIPACVVLKRVLLKHTKEIVSDLIDSCMKNLHNITGVLMTDSDFVSAVKRNLFNHGKQNA XP_004872068.1/1-841 PIPACVVLKRVLLKHTKEIMSDLFDSCMKNLHNITRVLMTDSDFVSAVKSNLFNRGKQNA ****.********:*****:***:*********** ************* ****: **** ENSP00000351327/1-854 TDIMEAMLKRLVSALIGEEKETKSQSLSYASLKAGSHDPKCRNQSLEFSTMKAEMKERDK ENSMUSP00000050962/1-849 ADIMEAMLKRLVSALLGEKKETKSQSLAYATLKAGTNDPKCKNQSLEFSAMKAEMKGKDK ENSRNOP00000003939/1-729 ADIMEAMLKRLVSALLGEKKETKSQSLAYATLKAGTHDPKCKNQSLEFSAMKAEMKGKDK ENSCPOP00000008074/1-804 ADIMEAMLKRLVSALLGEKKETKSQSLSYASLKAGSQDPKCKNQSLEFSAMKAEMKGKDK XP_004872068.1/1-841 ADLMEAMLNRLVSALLSE-KETESQSLSYATLKTGSQDPKCKNQSLEFSSMKAEMKGKDK :*:*****:******:.* ***:****:**:**:*::****:*******:****** :** ENSP00000351327/1-854 GKMKSDP-CKSLTSAEKVGEHILKEGLTIW-NQKQGNSCKVATKA-CSNKDEKGEKINAS ENSMUSP00000050962/1-849 CKSKADPCCKSLTSAERVSEHILKESLTMWNNQKQGNQGKVTNKVCCTSKDEKREKISPS ENSRNOP00000003939/1-729 GKTKGDPCCKSLTSAERVSEHILKESLTMWNNQKQGTQGRVPNKV-CPSKDEKREKISPS ENSCPOP00000008074/1-804 GK-KSDQ-CKSLTSAEKVGEHILKESLTMW-NQKQGNPCKMAAKL-CASKDEKKENISSS XP_004872068.1/1-841 SKMKSDQ-CKSLTSAEKVSEHILKESLTMW-NQKQGNPCKRATKL-CANKDEKKENISPS * *.* ********:*.******.**:* *****. : . * *..**** *:*..* ENSP00000351327/1-854 TDSLAKDLIVSALKLIQYHLTQQTKGKDTCEEDCPGSTMGYMAQSTQYEKCGGGQSAKAL ENSMUSP00000050962/1-849 TDSLAKDLIVSALMLIQYHLTQQAKGKDPCEEECPGSSMGYMSQSAQYEKCGGGQSSKSL ENSRNOP00000003939/1-729 TDSLAKDLIVSALMLIQYHLTQQAKGKDPCEEECPGSSMGYMSQSAQYEKSGGGQSSKSL ENSCPOP00000008074/1-804 TDSLAKDLIVSALRLIQYHLTQQAKGKDVLDEDCSGSSLGYMAQSTQYEKCGSGQNARTL XP_004872068.1/1-841 MDSLAKDLIVSALRLIQYHLIQQAKGKDTLEEDCPGSSLGYVAPSTQYEKCGGCQSTRTL ************ ****** **:**** :*:*.**::**:: *:****.*. *.:::* ENSP00000351327/1-854 SVKQLESHRAPGPSTCQKENQHLDSQKMDMSNIVLMLIQKLLNENPFKCEDPCEGENK-C ENSMUSP00000050962/1-849 SMKHFETRGAPGPSTCMKENQ-LESQKMDMSNMVLSLIQKLLSESPFSCDELTESDNKRC ENSRNOP00000003939/1-729 SMKHFESRGAPGPSTCAKENQ-LESQKMDMSNMVLSLIQKLLSESPFSCDELSESENKRC ENSCPOP00000008074/1-804 SMKHLESRGGPGPSTSLKENQQLASQKLDMSNIVLSLIQKLLSESPFSCDELCEGENK-S XP_004872068.1/1-841 SVKHLESRGTPGPSTSLKENQQLDCQKLDMSNIVLSLIQKLLSESPFSCDKLCEGENK-S *:*::*:: *****. **** * .**:****:** ******.*.**.*:. *.:** . ENSP00000351327/1-854 SEPRASKAASMSNRSDKAEEQCQEHQELDCTSGMKQANGQFIDKLVESVMKLCLIMAKYS ENSMUSP00000050962/1-849 CDPRSSKAAPMAKRP---EEQCQDNAELDFISGMKQMNRQFIDQLVESVMKLCLIMAKYS ENSRNOP00000003939/1-729 CDSRSKQAAPVAKRP---EDQSQDSTEMDFISGMKQMNRQFIDQLVESVMKLCLIMAKYS ENSCPOP00000008074/1-804 SEPRTNKASSVARRCDRGEVQCQDNAELDFVSGMKQMNRQFIDQLVESVMKLCMIMANYS XP_004872068.1/1-841 SEPRTNKASSMARRPDR-EVQCQDNAELDSISGMKQMNHQFIDQLVESVMKLCMIMANCS .:.*:.:*:.::.* * *.*: *:* ***** * ****:*********:***: * ENSP00000351327/1-854 NDGAALAELEEQAASANKPNFRGTRCIHSGAMPQNYQDSLGHEVIVNNQCSTNSLQKQLQ ENSMUSP00000050962/1-849 NNGAALAELEEQAALVGS----GSRCGRDAMMSQNYSETPGPEVIVNNQCSTTNLQKQLQ ENSRNOP00000003939/1-729 NNGAALAELEEQAALAS------------------------------------------- ENSCPOP00000008074/1-804 N-REAFAELEEQEAGFSN---NVNRCGQEATMSRN-RDSPRPEVIVNNQCSTSNLQKQLQ XP_004872068.1/1-841 NNREAFAELEEREAGLTN-NAGSSRHGQETTVLKN-QDYPGPEVIVNNQCSTSNLQKQLQ * *:*****: * ENSP00000351327/1-854 AVLQWIAASQFNVPMLYFMGDKDGQLEKLPQVSAKAAEKGYSVGGLLQEVMKFAKERQPD ENSMUSP00000050962/1-849 AVLQWIAASQFNVPMLYFMGDDDGQLEKLPEVSAKAAEKGYSVGDLLQEVMKFAKERQLD ENSRNOP00000003939/1-729 ------------------------------------------------------------ ENSCPOP00000008074/1-804 AVLQWIAASEFNVPMLYFMGDDDGQLEKLPEVSAKAAEKGYSVGDLLQEVMKFAKERQLD XP_004872068.1/1-841 AVLQWIAASEFNVPMLYFMGDDDGQLEKLPEVSAKAAEKGYSVGDLLQEVMRFAKEQQLD ENSP00000351327/1-854 EAVGKVARKQLLDWLLANL ENSMUSP00000050962/1-849 EAVGNMARKQLLDWLLANL ENSRNOP00000003939/1-729 ------------------- ENSCPOP00000008074/1-804 EAVGNMAKKQLLDWLLTNL XP_004872068.1/1-841 EAVVNMPKKQLLDWLLTNL