CLUSTAL W(1.81) multiple sequence alignment ENSMUSP00000035216/1-977 ------------------MDEELYSRQLYVLGLPAMQRIQEAKVLLCGLQGLGAEVAKNL ENSRNOP00000062984/1-676 ------------------MDEELYSRQLYVLGLPAMQRIREAKVLLCGLQGLGAEVAKNL ENSP00000333266/1-1012 ---------MDALDASKLLDEELYSRQLYVLGSPAMQRIQGARVLVSGLQGLGAEVAKNL ENSCPOP00000008020/1-1022 QLLSSPAFRMAVKESSQRLDRELYSRQLPVLGLPAMQRIQEAKVLLSGLQGLGAEVAKNL XP_004834114.1/1-1010 ---------MAVLEPSEWLDKELYSRQLPVLGPPAMQRIREAKVLLSGLQGLGAEVAKNL :*.******* *** ******: *:**:.************* ENSMUSP00000035216/1-977 VLTGVGSLTLHDPHPTCWADLAAQCFLSEESLGRNRAEASQAQLAQLNEAVQISVHSGDI ENSRNOP00000062984/1-676 VLMGVGSLTLHDPHPTCWADLAAQFFLSEESLGRSRAEASQPQLAQLNEAVQISVHRGDI ENSP00000333266/1-1012 VLMGVGSLTLHDPHPTCWSDLAAQFLLSEQDLERSRAEASQELLAQLNRAVQVVVHTGDI ENSCPOP00000008020/1-1022 VLMGVGSLTLHDPQPTCWSDLAAQFLLSEKDLGKSRAEASQKHLAQLNEAVQVFVHASDI XP_004834114.1/1-1010 VLMGVGSLTLHDPHPTCWSDLAAQVFLSERDLGKSRAEASQEHLAQLNEAVQVFVHPSDI ** **********:****:***** :***..* :.****** *****.***: ** .** ENSMUSP00000035216/1-977 TEDLLQGFQVVVLTDSKLEDQLKVGPLCHKHGVRFLMAETRGLVGRLFCDFGEDFTVLDP ENSRNOP00000062984/1-676 TEDLVRGFQVVVLTDSKLEDQLNMGALCHKNRVYFLMAETRGLVGRLFCDFGEDFTVVDP ENSP00000333266/1-1012 TEDLLLDFQVVVLTAAKLEEQLKVGTLCHKHGVCFLAADTRGLVGQLFCDFGEDFTVQDP ENSCPOP00000008020/1-1022 TEDLLLKFQVVVLTSSKLEDQLTMGALCHKHGVCFIMADTRGLVGQVFSDFGDEFVVNDP XP_004834114.1/1-1010 TEDLLLKFQVVVLTASKLEEQLMVGALCHKHGICFLVADTRGLVGQLFCDFGDEFIVHDP ****: ******* :***:** :*.****: : *: *:******::*.***::* * ** ENSMUSP00000035216/1-977 TEVEPMTAAIQDISQGFPGIVTLRGDTKRHSFHDGDLVIFSDIEGMVELNSCSPQSVRVQ ENSRNOP00000062984/1-676 TEVEPTSAAIQDISQGSPGIVTLRGGSKRPSFYDGDLVMFSDIEGMVELNSHSPQPVRVQ ENSP00000333266/1-1012 TEAEPLTAAIQHISQGSPGILTLRKGANTHYFRDGDLVTFSGIEGMVELNDCDPRSIHVR ENSCPOP00000008020/1-1022 TETEPLSPDIQHITQCSPDILTLREEDKELSFCDGDLVTFSGIEDMVELNGCPSQPIHVQ XP_004834114.1/1-1010 TEAEPLTAAIQHITQGFPGVLTLRGEDKEHSFCDGDLVTFSGIKGMVELNSCSPRPIRVQ **.** :. **.*:* *.::*** : * ***** **.*:.*****. .:.::*: ENSMUSP00000035216/1-977 KDGSLEIGDTTTFSRYLRGGVVTEVKRPKTVRHKPLDIALLQPHVVAQNTQEVQRAHCLH ENSRNOP00000062984/1-676 KDGSLEIGDTTTFSRYLRGGVVTEVKRPKTVKHKPLDIALLQPCMVVQNTQEIQRAHCLH ENSP00000333266/1-1012 EDGSLEIGDTTTFSRYLRGGAITEVKRPKTVRHKSLDTALLQPHVVAQSSQEVHHAHCLH ENSCPOP00000008020/1-1022 KDRSLEVEDTSTFSPYLCGGTVTKDKGSETVRHKPLDRALLEPCVVASNACEVRRALCLH XP_004834114.1/1-1010 KDRSLEIGDTSTFSPYLHGGIVTEVKRPETVRHKPLDRALIQPCVVAPSAQEAHRAHCLH :* ***: **:*** ** ** :*: * .:**:**.** **::* :*. .: * ::* *** ENSMUSP00000035216/1-977 QAFHVLHKFQQLHGRLPKPWDPDDAETVVELAQDLEPLKGTE----EESLDEALLRTIAL ENSRNOP00000062984/1-676 QTFHALHKFQQLHGRLPKPWDPDDAETVVWLAQDLEPLKGAK----EESLDEALLRTIAL ENSP00000333266/1-1012 QAFCALHKFQHLHGRPPQPWDPVDAETVVGLARDLEPLKRTEEEPLEEPLDEALVRTVAL ENSCPOP00000008020/1-1022 QAFRALHEFQHLYGRPLQPWDPVDAEIMVTLARNLGPLKEAE----EEPLDEALVRMVAL XP_004834114.1/1-1010 QAFRALHKFQNLHGRLPQPWDPVDAEIMVTLAQNLGPLKGAE----EEPLNEALLRTVAL *:* .**:**:*:** :**** *** :* **::* *** :: **.*:***:* :** ENSMUSP00000035216/1-977 SSAGTLSPMAAIMGGVAAQEVLKAISRKFMPLDQWLYFDALECLPEDETLLPSPEDCQPR ENSRNOP00000062984/1-676 SSAGSLSPMAAILGGVAAQEVLKAVSGKFMPLDQWLYFDALECLPEDETLLPSPEDCHPR ENSP00000333266/1-1012 SSAGVLSPMVAMLGAVAAQEVLKAISRKFMPLDQWLYFDALDCLPEDGELLPSPEDCALR ENSCPOP00000008020/1-1022 SSAGVLSPMAAILGAVAAQEVVKAISKKFMPLDQWLYFDALDCLPEDEKFLPNPEDCALK XP_004834114.1/1-1010 SSAGVLSPMASILGAVTAQEVLKAISRKFIPLDQWLYFDALDCLPEDEELFPNPEDCALR **** ****.:::*.*:****:**:* **:***********:***** ::*.**** : ENSMUSP00000035216/1-977 NCRYDGQIAVFGTDLQEKLSDQHYLLVGAGAIGCEMLKVFALVGLGVRANGGVTVADMDY ENSRNOP00000062984/1-676 NCRYDGQIAVFGTGFQEKLSYKHYLLVGAGAIGCEMLKGFALVGLGVRDNGGVTIADMDH ENSP00000333266/1-1012 GSRYDGQIAVFGAGFQEKLRRQHYLLVGAGAIGCELLKVFALVGLGAGNSGGLTVVDMDH ENSCPOP00000008020/1-1022 DWRYDGQIAVFGAGFQETLSCQRYLLVGAGAIGCELLKGFALMGLGAGTSGSVTVVDMDH XP_004834114.1/1-1010 DSRYDGQIAVFGAGFQETLSHQHYLLVGAGAIGCELLKGFALVGLGAGASGGVTVVDMDH . **********:.:**.* ::************:** ***:***. .*.:*:.***: ENSMUSP00000035216/1-977 IERSNLSRQFLFRPKDVRRPKAEVAAAAAHRLNPDLRATPYTCPLDPTTEDIYDDSFFSR ENSRNOP00000062984/1-676 VERSNLSRQFLFRPKDTGRPKAEVAAEAAHRLNPDLQVTSHTCPLDPTTEDIYDDDFFSR ENSP00000333266/1-1012 IERSNLSRQFLFRSQDVGRPKAEVAAAAARGLNPDLQVIPLTYPLDPTTEHIYGDNFFSR ENSCPOP00000008020/1-1022 IEYSNLSRQFLFRPWDIGKSKAEVAAAATQDLNPDLEVTAYTRILDHTTEDIYADNFFSH XP_004834114.1/1-1010 IEYSNLSRQFLFRPWDIDKPKAEVAAAATQDLNPDLEVMAHVQVLDHTTEHIYGDNFFSH :* **********. * :.****** *:: *****.. . . ** ***.** *.***: ENSMUSP00000035216/1-977 VNGVVAALDSFQARHYVAARCTHYLKPLLEAGTQGTWGSASVFVPYVTEAYRGPASDAAS ENSRNOP00000062984/1-676 VDGVVAALDSFQARHYVAARCTHYLKPLLEAGTQGTRGSASVFVPYVTEVYKGPT---SA ENSP00000333266/1-1012 VDGVAAALDSFQARRYVAARCTHYLKPLLEAGTSGTWGSATVFMPHVTEAYRAPASAAAS ENSCPOP00000008020/1-1022 VDGVVAAVDTFKARYYLSARCIHYLKPLLEAGTLGTKGSASVFVPHVTEVYKGPV--EAS XP_004834114.1/1-1010 VDGVVAAVDSFEARHYVAARCIHYLKPLLEAGTQGTKGSASVFVPYVTEVYKGPASAEAS *:**.**:*:*:** *::*** *********** ** ***:**:*:***.*:.*. :: ENSMUSP00000035216/1-977 EDAPYPVCTLRHIPSSMEHSVQWAQDQFEGLFRLSTETINCYQQTCTSLSATDRTETLAL ENSRNOP00000062984/1-676 EEAPYPVCTLRHFPSTVEHSLQWAQDEFEGLFRLSAETINDYQQC--------------- ENSP00000333266/1-1012 EDAPYPVCTVRYFPSTAEHTLQWARHEFEELFRLSAETINHHQQAHTSLADMDEPQTLTL ENSCPOP00000008020/1-1022 EGAPAPVCTLRYFPGTYEHTLQWAQNEFEELFRLPAETINRYQQAATSLEDVSGLQMLTS XP_004834114.1/1-1010 EDAPTPVCTMRRFPSTYEHTLEWARNEFEGLFRLSAETISCYQQACTSLADVDGPQMLTS * ** ****:* :*.: **:::**:.:** ****.:***. :** ENSMUSP00000035216/1-977 LQQVMGVLRTRPQTWQDCVVWALGHWQLCFHD------------KVLEGGTQFSSGSNKC ENSRNOP00000062984/1-676 -------LRT----------------ELCSGQD-----------------------PKSA ENSP00000333266/1-1012 LKPVLGVLRVRPQNWQDCVAWALGHWKLCFHYGIKQLLRHFPPNKVLEDGTPFWSGPKQC ENSCPOP00000008020/1-1022 LQLLLGVLRVRPQTWQDCVEWALGHWRLRFCDDIIRLLRLFPPYKVHEDGAPFWSGPKQC XP_004834114.1/1-1010 LQRVLGVLRVRPQTWRDCVMWALGHWQLCFHDDIIQLLSLLPPDKVHEDGTPFWSGPKRC **. .* .: . ENSMUSP00000035216/1-977 PHPLQFDPNHDMHFLYVLAAANLYARMHGLPGSQSQPALRELLTRLLESD-SRPQNLF-- ENSRNOP00000062984/1-676 HIPCNLIPTK-----------------------------------------TRISSMY-- ENSP00000333266/1-1012 PQPLEFDTNQDTHLLYVLAAANLYAQMHGLPGSQDWTALRELLKLLPQPDPQQMAPIF-- ENSCPOP00000008020/1-1022 PQPLEFDISQDMHFLYILAAANLYAQMHGLPGSLDQPALRVLLKLLLQTDPPHVASIFHR XP_004834114.1/1-1010 PQPLKFDISQDMHLLYILAAANLFAQMHGLPGSSDQIALRELLNLLLQTDPPHPAPVL-- * :: .: : : ENSMUSP00000035216/1-977 -----------SAEHGQEQLKELQETLDDWRKGPPLKPVLFVKDDDSNFHVDFVVAATDL ENSRNOP00000062984/1-676 -----------------------------WQ----------------------------- ENSP00000333266/1-1012 ASNLE--LASASAEFGPEQQKELNKALEVWSVGPPLKPLMFEKDDDSNFHVDFVVAAASL ENSCPOP00000008020/1-1022 KNTGDKGHSASTPLTDPEQLKELQESLEVWTKGPALKPLVFGKNEDSHFHVDFVRAAASL XP_004834114.1/1-1010 AESGE--HPEPTPLTGPEQLKELQEALEVWSKGPPLKSLVFEKDEDGNFHMDFVRAAASL * ENSMUSP00000035216/1-977 RCQNYGIL-PVNHARIKQIVGRIIPAIATSTAVVAGLLGLELYKVVSGLRSHGTFRHSYL ENSRNOP00000062984/1-676 -----------------------LP------TCMHGCMGCRAHKV--------------- ENSP00000333266/1-1012 RCQNYGIP-PVNRAQSKRIVGQIIPAIATTTAAVAGLLGLELYKVVSGPRPRSAFRHSYL ENSCPOP00000008020/1-1022 RSQNYGISEPADYAQSKRIMSQIIPAIATTTAAVAGLLGLEMYKVVGSPRPVGAFRHTYL XP_004834114.1/1-1010 QSQNYGISEPVDHAQSMRMVSQIIPAIATTTAAVAGLLGLELYKMVGRPRPVGAFRHTYL :* : : * :* . :*: ENSMUSP00000035216/1-977 HLAENHFIRSAPSAPAVQSFRDLKWTCWDRLKVPAVQPERTLKSLLAHLQEEHGLKVEML ENSRNOP00000062984/1-676 -------------------------------RLHSGN----------------------- ENSP00000333266/1-1012 HLAENYLIRYMPFAPAIQTFHHLKWTSWDRLKVPAGQPERTLESLLAHLQEQHGLRVRIL ENSCPOP00000008020/1-1022 DLAGNRLERSVPSAPAIQNFHHLQWTHWDRLKVHAGHPEMTLESLLAHLQEHHGLKVTML XP_004834114.1/1-1010 HLAENRLQRSVPSTPAIQKFHHLEWTRWDRLKVPAGQPERTLESLLAHLQEQHGLNVRML :: : : ENSMUSP00000035216/1-977 LHHQALLYSSGWSSEKQAQHLCLRVTELVQHVTGWKPKPG-LKVLVFELSCEGEEEEMAF ENSRNOP00000062984/1-676 --------------------------------------------------C--------- ENSP00000333266/1-1012 LHGSALLYAAGWSPEKQAQHLPLRVTELVQQLTGQAPAPG-QRVLVLELSCEGDDEDTAF ENSCPOP00000008020/1-1022 LYDNALLYSAQDSAECQAQRLPLRVTELVQQVTGWVPEPERQRVLVLELSCEGEEDDTAF XP_004834114.1/1-1010 LRGQALLYSARWSPESQAQYLPLRVTELVQQETDWVPEPG-LRVLVLELSCEGEEDNTAF * ENSMUSP00000035216/1-977 PPLHYEL- ENSRNOP00000062984/1-676 -------- ENSP00000333266/1-1012 PPLHYEL- ENSCPOP00000008020/1-1022 PPLHYELL XP_004834114.1/1-1010 PPLHYELW