CLUSTAL W(1.81) multiple sequence alignment ENSCPOP00000007885/1-761 -----------G------------------------------------------------ XP_004856991.1/1-799 -----------MEDGS-----------------------------SNSTSCFRRLTECFL ENSP00000438284/1-789 -----------MEDGP-----------------------------SNNASCFRRLTECFL ENSMUSP00000086485/1-796 -----------MEDGP-----------------------------SNNASCFRRLTECFL ENSRNOP00000060834/1-849 PAGCLPITFKGGSKGPALLALRNRTDSRGQMSNDSPEGAVGSCNATGSTGSTGELGKEFH ENSCPOP00000007885/1-761 ------------------LTDEKVKAYLSLHPQVLDEFVSESVSTETVEKWLRRKNDKFG XP_004856991.1/1-799 SPS---------------LTDEKVKAYLSLHPQVLDEFVSESVSAETVEKWLKRKNNKLE ENSP00000438284/1-789 SPS---------------LTDEKVKAYLSLHPQVLDEFVSESVSAETVEKWLKRKNNKSE ENSMUSP00000086485/1-796 SPS---------------LTDEKVKAYLSLHPQVLDEFVSESVSAETVEKWLKRKTNKAK ENSRNOP00000060834/1-849 TPPRRKSASDSRLALCMGLTDEKVKAYLSLHPQVLDEFVSESVSAETVEKWLKRKNNKAE **************************:*******:**.:* ENSCPOP00000007885/1-761 DDSTPKEVSRYQDTNMQGVVYELNSYIEQRLDTGGDNQLLLYELSSIIKVATKADGFALY XP_004856991.1/1-799 DDSAPKEVSRYQDTNMQGVVYELNSYIEQRLDTGGDNHLLLYELSSIIKVATKADGFALY ENSP00000438284/1-789 DESAPKEVSRYQDTNMQGVVYELNSYIEQRLDTGGDNQLLLYELSSIIKIATKADGFALY ENSMUSP00000086485/1-796 DEPSPKEVSRYQDTNMQGVVYELNSYIEQRLDTGGDNHLLLYELSSIIRIATKADGFALY ENSRNOP00000060834/1-849 DEPSPKEVSRYQDTNMQGVVYELNSYIEQRLDTGGDNHLLLYELSSIIRIATKADGFALY *:.:*********************************:**********::********** ENSCPOP00000007885/1-761 FLGECNNSLCVFTPPGIKEGKPRLIPAGPITQGTTISAYVAKSRKTLLVEDILGDERFPN XP_004856991.1/1-799 FLGECNNSLCMFTPPGIKERKPRLIPAGPITQGTTISAYVAKSRKTLLVEDILGDERFPR ENSP00000438284/1-789 FLGECNNSLCIFTPPGIKEGKPRLIPAGPITQGTTVSAYVAKSRKTLLVEDILGDERFPR ENSMUSP00000086485/1-796 FLGECNNSLCVFIPPGMKEGQPRLIPAGPITQGTTISAYVAKSRKTLLVEDILGDERFPR ENSRNOP00000060834/1-849 FLGECNNSLCVFTPPGMKEGQPRLIPAGPITQGTTISAYVAKSRKTLLVEDILGDERFPR **********:* ***:** :**************:***********************. ENSCPOP00000007885/1-761 GTGLESGPRIQSVLCLPIVTAIGDLIGILELYRYWGKDAFCLSHQEVATANLAWASVAIH XP_004856991.1/1-799 GTGLESGTRIQSVLCLPIITAIGDLIGILELYRHWGKEAFCLSHQEVATANLAWASVAIH ENSP00000438284/1-789 GTGLESGTRIQSVLCLPIVTAIGDLIGILELYRHWGKEAFCLSHQEVATANLAWASVAIH ENSMUSP00000086485/1-796 GTGLESGTRIQSVLCLPIVTAIGDLIGILELYRHWGKEAFCLSHQEVATANLAWASVAIH ENSRNOP00000060834/1-849 GTGLESGTRIQSVLCLPIVTAIGDLIGILELYRHWGKEAFCLSHQEVATANLAWASVAIH *******.**********:**************:***:********************** ENSCPOP00000007885/1-761 QVQVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHK XP_004856991.1/1-799 QVQVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHK ENSP00000438284/1-789 QVQVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHK ENSMUSP00000086485/1-796 QVQVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHK ENSRNOP00000060834/1-849 QVQVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHK ************************************************************ ENSCPOP00000007885/1-761 NQELYSDLFDIGEEKEGKPVFKKTKEIRFSIEKGIAGQVARTGEVLNIPDAYADPRFNRE XP_004856991.1/1-799 NKELYSDLFDIGEEKEGKPVFKKTKEIRFSIEKGIAGQVARTGEVLNIPDAYADPRFNRE ENSP00000438284/1-789 NKELYSDLFDIGEEKEGKPVFKKTKEIRFSIEKGIAGQVARTGEVLNIPDAYADPRFNRE ENSMUSP00000086485/1-796 NKELYSDLFDIGEEKEGKPIFKKTKEIRFSIEKGIAGQVARTGEVLNIPDAYADPRFNRE ENSRNOP00000060834/1-849 NKELYSDLFDIGEEKEGKPVFKKTKEIRFSIEKGIAGQVARTGEVLNIPDAYADPRFNRE *:*****************:**************************************** ENSCPOP00000007885/1-761 VDLYTGYTTRNILCMPIVSRGSVIGVVQMVNKINGSAFSKTDENNFKMFAVFCALALHCA XP_004856991.1/1-799 VDLYTGYTTRNILCMPIVSRGSVIGVVQMVNKISGSAFSKTDENNFKMFAVFCALALHCA ENSP00000438284/1-789 VDLYTGYTTRNILCMPIVSRGSVIGVVQMVNKISGSAFSKTDENNFKMFAVFCALALHCA ENSMUSP00000086485/1-796 VDLYTGYTTRNILCMPIVSRGSVIGVVQMVNKISGSAFSKTDENNFKMFAVFCALALHCA ENSRNOP00000060834/1-849 VDLYTGYTTRNILCMPIVSRGSVIGVVQMVNKISGSAFSKTDENNFKMFAVFCALALHCA *********************************.************************** ENSCPOP00000007885/1-761 NMYHRIRHSECIYRVTMEKLSYHTVCSAEEWQGLMHFTLPARLCKEIELFHFDIGPFENM XP_004856991.1/1-799 NMYHRIRHSEYIYRVTMEKLSYHSICTAEEWQGLMHFTLPVRLCKEIELFHFDIGPFENM ENSP00000438284/1-789 NMYHRIRHSECIYRVTMEKLSYHSICTSEEWQGLMQFTLPVRLCKEIELFHFDIGPFENM ENSMUSP00000086485/1-796 NMYHRIRHSECIYRVTMEKLSYHSICTSEEWQGLMRFNLPARICRDIELFHFDIGPFENM ENSRNOP00000060834/1-849 NMYHRIRHSECIYRVTMEKLSYHSICTSEEWQGLMHFNLPARICRDIELFHFDIGPFENM ********** ************::*::*******:*.**.*:*::************** ENSCPOP00000007885/1-761 WPGIFVHMVHQSCGPFCFDLEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILKNNH XP_004856991.1/1-799 WPGIFVYMVHQSCGTSCFDLEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNND ENSP00000438284/1-789 WPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNH ENSMUSP00000086485/1-796 WPGIFVYMIHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNN ENSRNOP00000060834/1-849 WPGIFVYMIHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNN ******:*:*:***. **:*************************************:**. ENSCPOP00000007885/1-761 SLFTELERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQL XP_004856991.1/1-799 GLFTDLERKGLLIACLCHDLDHRGFSNTYLQKFDHPLAALYSTSTMEQHHFSQTVSILQL ENSP00000438284/1-789 TLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQL ENSMUSP00000086485/1-796 GLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQL ENSRNOP00000060834/1-849 GLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQL ***:**********************:******************************** ENSCPOP00000007885/1-761 EGHNIFSSLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMHQAGSLNLHNQSHRDRV XP_004856991.1/1-799 EGHNIFSALSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLHNQAHRDRV ENSP00000438284/1-789 EGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRV ENSMUSP00000086485/1-796 EGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLHNQSHRDRV ENSRNOP00000060834/1-849 EGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLHNQSHRDRV *******:***********************************:*:*****:**:***** ENSCPOP00000007885/1-761 IGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQG XP_004856991.1/1-799 IGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQG ENSP00000438284/1-789 IGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQG ENSMUSP00000086485/1-796 IGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKRDEVPQG ENSRNOP00000060834/1-849 IGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKRDEVPQG *****************************************************:****** ENSCPOP00000007885/1-761 QIGFYNAVAIPCYTTLSQILPPTEPLLKACRDNLSQWEKVIRGEETGLWISAEG------ XP_004856991.1/1-799 QIGFYNAVAIPCYSTLTQILPPTEPLLKACRDNLSQWEKVIRGEETGLWISAPAPASPPA ENSP00000438284/1-789 QLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGEETATWISSPSVAQKAA ENSMUSP00000086485/1-796 QLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLNQWEKVIRGEETAMWISGPGPAPSKS ENSRNOP00000060834/1-849 QLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLNQWEKVIRGEETAMWISGPATSKS-- *:***********:**:*****************.***********. ***. . ENSCPOP00000007885/1-761 -----TSEK------- XP_004856991.1/1-799 PVAEGTSEK--HPVKD ENSP00000438284/1-789 -----ASED------- ENSMUSP00000086485/1-796 -----TPEKLNVKVED ENSRNOP00000060834/1-849 -----TSEKPTRKVDD :.*.