CLUSTAL W(1.81) multiple sequence alignment ENSCPOP00000007853/1-1132 AIMSLTSAYQHKLAEKLTILNNRGQGVLIRMYNIKKVKLCIYQHIPYSPLLNKNLISLRM ENSMUSP00000035400/1-1134 --MSLTSAYQLKLAEKLTILNDRGQGVLIRMYNIKKT--CSDSKSKPPFLLEKSMESCLK ENSRNOP00000058936/1-1106 --MSLTSAYQHKLAEKLTILNDRGQGVLIRMYNIKKT--CSDPKSKPPFLLEKSMESCLK ENSP00000293373/1-1127 --MSLTSAYQHKLAEKLTILNDRGQGVLIRMYNIKKT--CSDPKSKPPFLLEKSMEPSLK XP_004872866.1/1-1134 --MSLTSAYQHKLAEKLTILNDRGQGVLIRMYNIKKT--CSDTKSKPSFLLEKSMESSVK ******** **********:**************. * : . **:*.: . ENSCPOP00000007853/1-1132 FRYCLCPQVTLINSQQHLGPVHREKSEIVRFLTSYYQSFVDVMEFRDHVYELLNTI-LCQ ENSMUSP00000035400/1-1134 YINKKFPNIDVRNSTQHLGPVHREKAEIIRFLTNYYQSFVDVMEFRDHVYELLNTIDACQ ENSRNOP00000058936/1-1106 YINKKFPNIDVRNSTQHLGPVHREKAEIIRFLTNYYQSFVDVMEFRDHVYELLNTIDACQ ENSP00000293373/1-1127 YINKKFPNIDVRNSTQHLGPVHREKAEIIRFLTNYYQSFVDVMEFRDHVYELLNTIDACQ XP_004872866.1/1-1134 YINKKFPNVDVRNSTQHLGPVHREKAEIIRFLTNYYQSFVDVMEFRDHVYELLNTIDACQ : *:: : ** **********:**:****.********************** ** ENSCPOP00000007853/1-1132 CHFDINLNFDFTRSYLDLIVTYTSVILLLSRIEDRRVLIGMYNCAHEMLHGHGDPSFARL ENSMUSP00000035400/1-1134 CHFDINLNFDFTRSYLDLIVTYTSVILLLSRIEDRRILIGMYNCAHEMLHGHSDPSFARL ENSRNOP00000058936/1-1106 CHFDINLNFDFTRSYLDLIVTYTSVILLLSRIEDRRLLIGMYNCAHEMLHGHGDPSFPRL ENSP00000293373/1-1127 CHFDINLNFDFTRSYLDLIVTYTSVILLLSRIEDRRILIGMYNCAHEMLHGHGDPSFARL XP_004872866.1/1-1134 CHFDINLNFDFTRSYLDLIVTYTSVILLLSRIEDRRVLIGMYNCAHEMLHGHSDSSFARL ************************************:***************.*.**.** ENSCPOP00000007853/1-1132 GQMVLEYDHPLKKLTEEFGPHTKAVSGALLSLHFLFVRRNQGAEQWRNAQLLSLLSTPPA ENSMUSP00000035400/1-1134 GQMVLEYDHPLKKLTEEFGPHTKAVSGALLSLHFLFVRRNQGAEQWRSAQLLSLISSPPA ENSRNOP00000058936/1-1106 GQMVLEYDHPLKKLTEEFGPHTKAVSGALLSLYFLFVRRNQGAEQWRSAQLLSLISSPPA ENSP00000293373/1-1127 GQMVLEYDHPLKKLTEEFGPHTKAVSGALLSLHFLFVRRNQGAEQWRSAQLLSLISNPPA XP_004872866.1/1-1134 GQMVLEYDHPLKKLTEEFGPHTKAMSGALLSLHFLFVRRNQGAEQWRSAQLLSLISTPPA ************************:*******:**************.******:*.*** ENSCPOP00000007853/1-1132 MINPANSETMACEYLSVEVMERWIIIGFLLCHGCLNSNSHCQKLWKLSLQGSLYVTLIRE ENSMUSP00000035400/1-1134 MINPANSDTMACEYLSVEVMERWIIIGFLLCHGCLNSNSQCQKLWKLCLEGSLYITLIRE ENSRNOP00000058936/1-1106 MINPANSDTMACEYLSVEVMERWIIIGFLLCHGCLNSNSQCQKLWKLCLEGSLYITLIRE ENSP00000293373/1-1127 MINPANSDTMACEYLSVEVMERWIIIGFLLCHGCLNSNSQCQKLWKLCLQGSLYITLIRE XP_004872866.1/1-1134 MINPAHSDTMACEYLSVEVMERWIIIGFLLCHGCLNSNSQCQKLWKLCLQGSLYITLIRE *****:*:*******************************:*******.*:****:***** ENSCPOP00000007853/1-1132 DVLQVHKVTEDLFSSLKGYGKRVADIKESKEYVIANSGQFHSQRRQFLRVAVKELETVLT ENSMUSP00000035400/1-1134 DVLQVHKVTEDLFSSLKGYSKRVADIKESKEHAITNSGQFHCQRRQFLRTAVKELETVLN ENSRNOP00000058936/1-1106 DVLQVHKVTEDLFSSLKGYSKRVADIKESKEHAITNSGQFHCQRRQFLRTAVKELETVLN ENSP00000293373/1-1127 DVLQVHKVTEDLFSSLKGYGKRVADIKESKEHVIANSGQFHCQRRQFLRMAVKELETVLA XP_004872866.1/1-1134 DVLQVHKVTEDLFSGLKGYGKRVADIKECKEHMIANSGQFHCQRRQFLRMTVKELETVLT **************.****.********.**: *:******.******* :******** ENSCPOP00000007853/1-1132 DEPGLLGPKALFAFMALSFIRDEVTWLVRHTENVTKTKTPEDYADSNIAELLFLLEEIRA ENSMUSP00000035400/1-1134 DEPGLLGPKALFAFMALSFIRDEVTWLVRHTENVTKTKTPEDYADSSIAELLFLLEEIRA ENSRNOP00000058936/1-1106 DEPGLLGPKALFAFMALSFIRDEVTWLVRHTENVTKTKTPEDYADS-IAELLFLLEEIRA ENSP00000293373/1-1127 DEPGLLGPKALFAFMALSFIRDEVTWLVRHTENVTKTKTPEDYADSSIAELLFLLEGIRS XP_004872866.1/1-1134 DEPGLLGPKALFAFMALSFIRDEVTWLVRHTENVTKTKTPEDYADSSIAELLFLLEEIRA ********************************************** ********* **: ENSCPOP00000007853/1-1132 LVRRHIKVIQQYHLQYLARFDALVLSDVIQNLSVCPEEESVIMSSFVSTLSSLNLKQVDS ENSMUSP00000035400/1-1134 LVRRHIKVIQQYHLQYLARFDVLVLSDIIQNLSVCPEEESVIMSSFVSILSSLNLKQVDN ENSRNOP00000058936/1-1106 LVRRHIKVIQQYHLQYLARFDVLVLSDIIQNLTVCPEEESVIMSSFVSTLSSLNLKQVDN ENSP00000293373/1-1127 LVRRHIKVIQQYHLQYLARFDALVLSDIIQNLSVCPEEESIIMSSFVSILSSLNLKQVDN XP_004872866.1/1-1134 LVRRHIKVIQQYHLQYLARFDVLVLSDIIQNLSVCPEEESVIMSSFVSTLSSLNLKQVDS *********************.*****:****:*******:******* **********. ENSCPOP00000007853/1-1132 GEKFEFSGLRLDWFRLQAYTSVAKAPLHLHENPDLAKVMNLIVFHSQMLDSVEKVLVETS ENSMUSP00000035400/1-1134 EEKFDFSGLRLDWFRLQAYTSVSKAPLHLHENPDLAKVMNLIIFHSQMLDSVEKMLVETS ENSRNOP00000058936/1-1106 EEKFDFSGLRLDWFRLQAYTSVAKAPLHLHENPDLAKVMNLIIFHSQMLDSVEKMLVETS ENSP00000293373/1-1127 GEKFEFSGLRLDWFRLQAYTSVAKAPLHLHENPDLAKVMNLIVFHSRMLDSVEKLLVETS XP_004872866.1/1-1134 GEKFEFSGLRLDWFRLQAYTSVAKAPLHLHENPDLAKVMNLIVFHSQMLDSVDKVLVETS ***:*****************:*******************:***:*****:*:***** ENSCPOP00000007853/1-1132 DLSTFCFHLRTFEKMFAMTLEEPTMLRYAIAFPLICTHFVHCTHEMCPEEYPHLKNHGLH ENSMUSP00000035400/1-1134 DLSTFCFHLRTFEKMFATTLEEPTMLRYTIAFPLICAHFVHCVHEMCPEEYPHLKNHGLH ENSRNOP00000058936/1-1106 DLSTFCFHLRTFEKMFATTLEEPTMLRYTIAFPLICAHFVHCIHEMCPEEYPHLKNHGLH ENSP00000293373/1-1127 DLSTFCFHLRIFEKMFAMTLEESAMLRYAIAFPLICAHFVHCTHEMCPEEYPHLKNHGLH XP_004872866.1/1-1134 DLSTFCFHLRTFEKMFAMTLEEPTMLRYAIAFPLICAHFVHCTHEMCPEEYPHLKNHSLH ********** ****** ****.:****:*******:***** **************.** ENSCPOP00000007853/1-1132 HCNSFLEELAKQTSNCILEICAEQRNLSEQLLPKHCATTISKAKNKKTMKQRQAPRKGEP ENSMUSP00000035400/1-1134 HCNSFLEDLAKQTSNCVLEICAEQRNLNEQLLPKHCATTISKAKNKKSMKQRQAPRKGEP ENSRNOP00000058936/1-1106 HCNSFLEELAKQTSNCVLEICAEQRNLNEQLLPKHCATTISKAKNRKSMKQRQAPRKGEP ENSP00000293373/1-1127 HCNSFLEELAKQTSNCVLEICAEQRNLSEQLLPKHCATTISKAKNKKTRKQRQTPRKGEP XP_004872866.1/1-1134 HCNSFLEELAKQTSNCVLEICAEQRKLSNQLLPKHCATTISKAKNKKTMKQRQTPRKGEP *******:********:********:*.:****************:*: ****:****** ENSCPOP00000007853/1-1132 ERDKPGAESHRKNRSLVTNMDKLHQHLMELALTMNHVHTFSVFEHTIFPSEYLSSHLEAR ENSMUSP00000035400/1-1134 ERDKPGAESHRKNRSLVTNMDKLHLNLTELALAMNHVHSFSVFEHTIFPSEYLSSHLEAR ENSRNOP00000058936/1-1106 ERDKPGAESHRKNRSLVTNMDKLHLNLTELALAMNHVHSFSVFEHTIFPSEYLSSHLESR ENSP00000293373/1-1127 ERDKPGAESHRKNRSIVTNMDKLHLNLTELALTMNHVYSFSVFEHTIFPSEYLSSHLEAR XP_004872866.1/1-1134 ERDKPGAESRRKNRSLVTNMDKLHQHLMELALAMNHIHSFSVFEHTIFPSEYLSGHLEAR *********:*****:******** :* ****:***:::***************.***:* ENSCPOP00000007853/1-1132 LNRAIVCLAGYNTTTQEILRPSELLAGVKAYIGFIQSLAQFLGADVSRVIRNALLQQTQP ENSMUSP00000035400/1-1134 LNRAIVTLAGYNATTQEILRPSELLAGVKAYISFIQSLAQFLGADASRIVRNALLQQTQP ENSRNOP00000058936/1-1106 LNRAIVSLAGYNATTQEILRPSELLAGVKAYTSFIQSLAQFLGTDASRIVRNALLQQTQP ENSP00000293373/1-1127 LNRAIVWLAGYNATTQEIVRPSELLAGVKAYIGFIQSLAQFLGADASRVIRNALLQQTQP XP_004872866.1/1-1134 LSRAIVWLAGYNTTTQEILRPSELLAGVKAYIGFIQSMAQFLGADVCRVIRNALLQQTQP *.**** *****:*****:************ .****:*****:*..*::********** ENSCPOP00000007853/1-1132 LDSFGEQTITTLYTNWYLESLLRQASSGTIVLSPAMQAFISLPREGEQNFSAEEFSDISE ENSMUSP00000035400/1-1134 LDSSGEQTVTTLYTNWYLESLLRQASSGAIVLSPAMQAFISLPRDGEQNFSAEEFSDISE ENSRNOP00000058936/1-1106 LDSCGEQTVTTLYTNWYLESLLRQASSGTIVLSPAMQAFISLPRDGEQNFSAEEFSDISE ENSP00000293373/1-1127 LDSCGEQTITTLYTNWYLESLLRQASSGTIILSPAMQAFVSLPREGEQNFSAEEFSDISE XP_004872866.1/1-1134 LDSCGEQTITTLYTNWYLESLLRQASSGTIVLSPAMQAFVSLPREGEQNFSAEEFSDVSE *** ****:*******************:*:********:****:************:** ENSCPOP00000007853/1-1132 MRALAELLGPYGMKFLSENLMWHVTSQIVELKKLVVENMDTLVQIRSNFSKPDLMASLLP ENSMUSP00000035400/1-1134 MRALAEILGPYGMKFLSENLMWHVTSQIVELKKLVVENMDILVQIRSNFSKPELMASLLP ENSRNOP00000058936/1-1106 MRALAEILGPYGMKFLSENLMWHVTSQIVELKKLVVENMDILVQIRSNFTKPELMASLLP ENSP00000293373/1-1127 MRALAELLGPYGMKFLSENLMWHVTSQIVELKKLVVENMDILVQIRSNFSKPDLMASLLP XP_004872866.1/1-1134 MRALAELLGPYGMKFLSENLMWHVTSQIVELKKLVVENMDTLVQIRSNFSKPDLMASLLP ******:********************************* ********:**:******* ENSCPOP00000007853/1-1132 QLTGAENVLKRMTIIGVILSFRAMAQEGLREVFSSHCPFLMGPIECLKEFVTPDTDIKVT ENSMUSP00000035400/1-1134 QLTGAENVLKRMTIIGVILSFRAMAQEGLQEVFSAHCPFLMGPIECLKEFVTPDTDIKVT ENSRNOP00000058936/1-1106 QLTGAENVLKRMTIIGVILSFRAMAQEGLQE---------------------------VT ENSP00000293373/1-1127 QLTGAENVLKRMTIIGVILSFRAMAQEGLREVFSSHCPFLMGPIECLKEFVTPDTDIKVT XP_004872866.1/1-1134 QLTGAENVLKRMTIIGVILSFRAMAQDGLREVFSSHCPFLMSPIECLKEFVTPDTDIKVT **************************:**:* ** ENSCPOP00000007853/1-1132 LSVFELASAAGVDCDIDPALVAAIANLKADNSSPEEEYKVACLLLIFLAVSLPLLATDPS ENSMUSP00000035400/1-1134 LSVFELACAAGVSCDIDPALVAAIANLKADNSSPEEEYKVACLLLIFLAVSLPLLATDPS ENSRNOP00000058936/1-1106 LSVFELACAAGVSCDIDPALVAAIANLKADNSSPEEEYKVACLLLIFLAVSLPLLATDPS ENSP00000293373/1-1127 LSIFELASAAGVGCDIDPALVAAIANLKADTSSPEEEYKVACLLLIFLAVSLPLLATDPS XP_004872866.1/1-1134 LSVFELASAAGVGCDIDPALVAAIANLKADNSSPEEEYKLACLLLIFLAVSLPLLATDPS **:****.****.*****************.********:******************** ENSCPOP00000007853/1-1132 SFYSIEKDGYNNNIHCLTKAIIQVSAALFTLYNKNIETHLKEFLVVASVSLLQLGQETDK ENSMUSP00000035400/1-1134 SFFSIEKDGYNNNIHCLTKAIIQVSAALFTLYNKNIETHLKEFLVVASVSLLQLGQETDK ENSRNOP00000058936/1-1106 SFFSIEKDGYNNNIHCLTKAIIQVSAALFTLYNKNIETHLKEFLVVASVSLLQLGQETDK ENSP00000293373/1-1127 SFYSIEKDGYNNNIHCLTKAIIQVSAALFTLYNKNIETHLKEFLVVASVSLLQLGQETDK XP_004872866.1/1-1134 SFYSIEKDGYNNNIHCLTKAIIQVSAALFTLYNKNIETHLKEFLVVSSSSLLQLGQETDK **:*******************************************:* *********** ENSCPOP00000007853/1-1132 LKTRNRESISLLMRLVVEESSFLTLDMLESCFPYVLLRNAYREVSRAFHLSRV----- ENSMUSP00000035400/1-1134 LKTRNRESISLLMRLVVEESPFLTLDMLESCFPYVLLRNAYREVSRAFYLNRLPASSH ENSRNOP00000058936/1-1106 LKTRNRESISLLMRLVVEESPFLTLDMLESCFPYVLLRNAYREVSRAFYLNRLPASSH ENSP00000293373/1-1127 LKTRNRESISLLMRLVVEESSFLTLDMLESCFPYVLLRNAYREVSRAFHLN------- XP_004872866.1/1-1134 LKTRNRESISLLMRLVVEESSFLTLDMLESCFPYVLLRNAYREVSRAFHLNRVPANTY ********************.***************************:*.